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High level of estradiol in a Holstein-Friesian cow with sacroiliac luxation after calving

  • Mamuad, Lovelia L.;Seo, Bosung;Kang, Seogjin;Cho, Yong-Il
    • Korean Journal of Veterinary Research
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    • v.60 no.4
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    • pp.237-240
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    • 2020
  • This is the report of sacroiliac luxation in a Holstein-Friesian cow, describing the progression of the sacroiliac luxation from the onset of its development with changes in estradiol (E2) and serum chemistry. The high estrogen concentration was assumed to be a predisposing factor of the disease that relaxed the pelvic muscles and a secondary slippery finally caused the sacroiliac luxation. The E2 was present at levels four times higher in the cow with sacroiliac luxation (167 pg/mL) than in normal cows. Above normal levels of creatinine kinase, aspartate aminotransferase, and lactate dehydrogenase were also observed in cow with sacroiliac luxation.

Dual-phase-lag model on thermo-microstretch elastic solid Under the effect of initial stress and temperature-dependent

  • Othman, Mohamed I.A.;Zidan, Magda E.M.;Mohamed, Ibrahim E.A.
    • Steel and Composite Structures
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    • v.38 no.4
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    • pp.355-363
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    • 2021
  • The present paper attempts to investigate the propagation of plane waves in an isotropic elastic medium under the effect of initial stress and temperature-dependent properties. The modulus of elasticity is taken as a linear function of the reference temperature. The formulation is applied under the thermoelasticity theory with dual-phase-lag; the normal mode analysis is used to obtain the expressions for the displacement components, the temperature, the stress, and the strain components. Numerical results for the field quantities are given in the physical domain and illustrated graphically. Comparisons are made with the results predicted by different theories (Lord-Shulman theory, the classical coupled theory of thermoelasticity and the dual-phase-lag model) in the absence and presence of the initial stress as well as the case where the modulus of elasticity is independent of temperature.

LARGE DEVIATIONS FOR A SUPER-HEAVY TAILED 𝛽-MIXING SEQUENCE

  • Yu Miao;Qing Yin
    • Journal of the Korean Mathematical Society
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    • v.61 no.5
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    • pp.853-874
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    • 2024
  • Let {X, Xn; n ≥ 1} be a 𝛽-mixing sequence of identical nonnegative random variables with super-heavy tailed distributions and Sn = X1 + X2 + · · · + Xn. For 𝜀 > 0, b > 1 and appropriate values of x, we obtain the logarithmic asymptotics behaviors for the tail probabilities ℙ(Sn > e𝜀nx) and P(Sn > e𝜀bn). Moreover, our results are applied to the log-Pareto distribution and the distribution for the super-Petersburg game.

The Effects of Yanghyulsamultanggamibang to Allergic Contact Dermatitis (양혈사물탕가미방(凉血四物湯加味方)이 Allergy성(性) 접촉(接觸) 피부염(皮膚炎)에 미치는 영향(影響))

  • Kim, Chang-Hwan;Kim, Kyung-Jun
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.18 no.1
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    • pp.13-26
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    • 2005
  • Experimental drug was applied to a white male mouse taken ill with allergic contact dermatitis to investigate the effects of Yanghyulsamultanggamibang. 1. In case of skin moisture, when it was checked 72 hours later, there showed up meaningful differences among the normal, control, and sample groups. Especially, the moisture increased more noticeably in the sample group than in the control group. 2. With regards to RBC count in blood, it increased more in the control and sample groups than in the normal group when it was checked both in 24 hours and 72 hours. When it was checked in 48 hours, the number of RBC in the sample group increased the most, and the count in the control group increased more than in the normal group. 3. About the neutrophil rate in WBC count, it increased meaningfully more both on the control and sample groups than in the normal group in 24 hours. When the rate was checked in 48 hours, it increased the most in the sample group, and it increased more in the control group than in the normal group. When in checked72 hours later, it increased substantially more in the control group than both the sample and normal group. 4. As of the lymphocyte rate in WBC count, when measured in 24 hours, it increased in the normal group than in the control and sample groups. In 48 hours, it increased the most in the normal group, and it increased meaningfully more in the control group than in the sample group. 5. Regarding the total IgE, when measured 24 hours later, it increased noticeably more in the normal group than in the control and sample groups. In 48 hours, there showed up substantial differences among the normal, control and sample groups. In particular, it increased meaningfully more in the control group than in the sample group. 6. When the sample of skin tissue was examined, the corneal layer restoration increased more in the sample group than in the normal group. The above-mentioned results prove that Yanghyulsamultanggamibang can be taken when allergic contact dermatitis develops on the skin. Long-term observation afterward is also advised.

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Effect of Scutellaria baicalensis Water Extract on Antioxidative Activity and Epidermal Thickness in DNCB-induced Allergic Contact Dermatitis Animal Model (황금열수추출물이 DNCB로 유도된 알레르기성 접촉피부염 흰쥐의 항산화능 및 표피회복능에 미치는 영향)

  • Kim, Yun-Hee;Park, Young-Sook
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.35 no.5
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    • pp.543-548
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    • 2006
  • After allergic contact dermatitis (ACD) elicited by application of 1 mL of 2.5% 1-chloro-2,4-dinitrochloro-benzene (DNCB) onto dorsal skin, Sprague Dawley male rats fed Scutellaria baicalensis water extract were observed to investigate the mitigative effect of Scutellaria baicalensis water extract on ACD. The Scutellaria baicalensis water extract (100 mg/kg/day) was daily administered to rats suffered from ACD. Concentrations of TBARS in plasma and liver were increased in rats with ACD. The concentrations of TBARS in liver were significantly decreased in Scutellaria baicalensis-fed group (SBFG) compared to control group (CG), but not in plasma. Liver SOD activity was significantly increased in SBFG compared to that of normal group and CG. Serum Ig E level was significantly increased in CG compared to normal group, while that of SBFG was significantly decreased. The epidermal thickness of CG was significantly increased compared to that of normal group, while that of SBFG was significantly decreased compared to that of CG. These results indicated that the Scutellaria baicalensis water extract administration was effective for antioxidative activity in liver, serum Ig E level and epidermal thickness of rats with ACD.

The Antioxidant Effects of Sesimting on the Brain Tissue of Rat (세심탕(洗心湯)이 뇌조직(腦組織)의 산화작용(酸化作用)에 미치는 영향(影響))

  • Kim Seong-Hyeon;Lee Sang-Ryong
    • Journal of Oriental Neuropsychiatry
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    • v.8 no.2
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    • pp.39-50
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    • 1997
  • This experiment was to investigate the antioxidant effect of Sesimtang(SST) on brain tissues of mouse. The experimental groups were divided into three groups and treated ad follows for 15 days ; Normal group(NC), Vt.E admistrated group(PC), SST administrated Group(SST). After the extracting microsome from brain of mouse, those were measured the amounts of oxidant materials like MDA(malonaldehyde) and $H_2O_2$, then activities of antioxidant enzymes like SOD(superoxide dismutase), catalase, NADPH-cytochrome P-450 reductase. The results were as follows; 1. In TBA reaction to measure the amount of MDA, oxidant material of brain tissue of aged rat, both treated groups showed significant decrease. 2. Hydrogen peroxide formation was showed significant decrease in both treated groups than normal group. 3. Superoxide dismutase activity was increased in both treated groups than normal group, and showed little change in SST administrated group than normal group. 4. Catalase activity was increased in both treated groups than normal group. 5. NADPH-cytochrome P-450 reductase activity was increased in both treated groups than normal group.

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Experimental comparability between steam and normal curing methods on tensile behavior of RPC

  • Guo, Min;Gao, Ri
    • Advances in concrete construction
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    • v.11 no.4
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    • pp.347-356
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    • 2021
  • To address the limitation of the commonly used steam curing of reactive powder concrete (SC-RPC) in engineering, a preparation technology of normal curing reactive powder concrete (NC-RPC) is proposed. In this study, an experimental comparative research on the mechanical properties of NC-RPC and SC-RPC under uniaxial tension is conducted. Under the premise of giving full play to the ultra-high performance of RPC, the paper tries to explore whether normal curing can replace steam curing. The results show that various mechanical indexes of NC-RPC (e.g., tensile strength, ultimate tensile strain, elastic modulus and deformation performance) could basically reach the mechanical index values in steam curing at 28d age, some performance is even better at a longer age. So it affirms the feasibility of normal curing. In this paper, the influence of normal curing age on the tensile properties of RPC is discussed, and the relationship between each index and age is introduced in detail. Based on the experimental data, the tensile mechanism of RPC is analyzed theoretically, and two kinds of tensile constitutive models for RPC are proposed, one is curvilinear model, and another one is polygonal line model. The validity of the two models is further verified by the test results of others.

Hypoglycemic and Antioxidative Effects of Dietary Sea-Tangle Extracts Supplementation in Streptozotocin-Induced Diabetic Rats (Streptozotocin-유발 당뇨쥐에서 다시마 추출물 첨가식이의 항당뇨 및 항산화 효과)

  • 조영자;방미애
    • Journal of Nutrition and Health
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    • v.37 no.1
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    • pp.5-14
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    • 2004
  • The purpose of this study was to investigate the effect of dietary sea-tangle extracts on blood glucose levels, serum lipid levels, thiobarbituric acid reactive substance (TBARS) and glutathione enzymes in diabetic rats treated with streptozotocin (STZ) Four groups of rats (Sprague-Dawley male rats, 180 - 200g) were consisted of normal rats fed control diet (C), diabetic rats fed control diet (CD), normal rats fed sea-tangl extracts diet (E), and diabetic rats fed sea-tangle extracts diet (ED). Diabetes was induced by single injection of streptozotocin (60 mg/kg B.W.). After 7 weeks, rats were sacrificed, serum glucose, serum total cholesterol, triglyceride levels and glutathione enzymes were measured. Urine was significantly higher in CD and ED groups than those of others (p < 0.05). Levels of amylase, calcium, uric acid, hemoglobin, cholesterol and low density lipoprotein (LDL)-cholesterol were different among four groups. But high density cholesterol (HDL)-cholesterol of ED group was significantly higher (p < 0.05) than other groups (C and E group) And the weekly change of serum glucose was decreased in the 3th,4th and 5th weeks. But serum triglyceride (TG) of diabetic rats fed sea-tangle extracts diet (ED) was lower than diabetic rats fed control diet (CD). Activity of hepatic microsomal G6Pase was significantly increased CD and ED groups higher than C and E group, but kidney was decreased ED group. Hepateic glutathione S-transferase (GST) of CD and ED group were significantly lower than C and E group (p<0.05), glutathione peroxidase (GPX) of E and ED group were significantly higher than C and CD group (p<0.05), glutathione reductase (GR) activities of ED group was significantly lower than other groups, malondialdehyde (MDA) of ED was lower than E and CD group, but kidney was increased significant in ED group compared to liver. These results suggested that dietary sea-tangle extracts reduce .hepatic disorders such as oxidant than kidney. In conclusion, dietary sea-tangle extracts groups reduced blood TG and hepatic MDA levels in STZ-induced diabetic rats.

Antidiabetic activity of Argyreia speciosa (sweet) (Burm.f.)Boj. in normoglycemic and Streptozotocin-induced diabetic rats

  • Habbu, P.V.;Mahadevan, K.M.;Kulkarni, V.H.;Marietta, P.;Pratap, V.;Thippeswamy, B.S.;Veerapur, V.P.
    • Advances in Traditional Medicine
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    • v.10 no.2
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    • pp.90-102
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    • 2010
  • Effect of ethanol (ASE) and water (ASW) extracts of Argyreia speciosa on blood glucose and lipid profile was investigated in normoglycemic and Streptozotocin (STZ)-induced diabetic animals. In oral glucose and sucrose tolerance test, treatment with ASE and ASW (100 and 200 mg/kg) and Glidenclamide (10 mg/kg) significantly improved the glucose and sucrose tolerance in normal animals. In addition, respective treatment for fifteen-day resulted in significant percentage reduction in serum glucose (SG) ie., 30.39% (lower dose of ASE) and 33.21% (higher dose of ASW). In standardized STZ (50 mg/kg, iv)-induced diabetic rats, a single dose of ASE and ASW treatment exhibited reduction in SG levels at different time intervals compared to basal levels. Administration of both the doses of ASE and ASW for fifteen-day days exhibited greater percentage reduction in glycemia (24.6%, 24.7%, 23.9% and 21.9% respectively) and also ameliorated restored to near normal value of all tested lipid parameters. Further, treatment also exhibited significantly improved glucose tolerance over the period of 120 min compared to diabetic control group. Eventhough treatment failed to increase serum insulin levels significantly but peripheral utilization of insulin was increased as evident by insulin tolerance test. Taken together, present study supports the traditional usage of title plant in the treatment of diabetes mellitus.

Shear behavior of foam-conditioned gravelly sands: Insights from pressurized vane shear tests

  • Shuying Wang;Jiazheng Zhong;Qiujing Pan;Tongming Qu;Fanlin Ling
    • Geomechanics and Engineering
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    • v.34 no.6
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    • pp.637-648
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    • 2023
  • When an earth pressure balance (EPB) shield machine bores a tunnel in gravelly sand stratum, the excavated natural soil is normally transformed using foam and water to reduce cutter wear and the risk of direct muck squeezing out of the screw conveyor (i.e., muck spewing). Understanding the undrained shear behavior of conditioned soils under pressure is a potential perspective for optimizing the earth pressure balance shield tunnelling strategies. Owing to the unconventional properties of conditioned soil, a pressurized vane shear apparatus was utilized to investigate the undrained shear behavior of foam-conditioned gravelly sands under normal pressure. The results showed that the shear stress-displacement curves exhibited strain-softening behavior only when the initial void ratio (e0) of the foam-conditioned sand was less than the maximum void ratio (emax) of the unconditioned sand. The peak and residual strength increased with an increase in normal pressure and a decrease in foam injection ratio. A unique relation between the void ratio and the shear strength in the residual stage was observed in the e-ln(τ) space. When e0 was greater than emax, the fluid-like specimens had quite low strengths. Besides, the stick-slip behavior, characterized by the variation coefficient of measured shear stress in the residual stage, was more evident under lower pressure but it appeared to be independent of the foam injection. A comparison between the results of pressurized vane shear tests and those of slump tests indicated that the slump test has its limitations to characterize the chamber muck fluidity and build the optimal conditioning parameters.