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Zinc status and growth of Korean infants fed human milk, casein-based, or soy-based formula: three-year longitudinal study

  • Han, Young-Hee;Yon, Mi-Yong;Han, Heon-Seok;Johnston, Kelley E.;Tamura, Tsunenobu;Hyun, Tai-Sun
    • Nutrition Research and Practice
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    • v.5 no.1
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    • pp.46-51
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    • 2011
  • To evaluate the effect of feeding methods on growth and zinc nutritional status of infants early in life, we monitored from birth to 36 months in 51 infants who were exclusively fed human milk (HM, n=20), casein-based formula (CBF, n=12), or soy-based formula (SBF, n=19) during the first five months of life. Zinc status was assessed by analyzing serum zinc concentrations and zinc intakes. Zinc contents in HM and formulas were measured. Zinc intake was estimated by weighing infants before and after feeding in the HM group and by collecting formula-intake records in the CBF and SBF groups. After solid foods were introduced, all foods consumed were also included to estimate zinc intake. The growth of infants in all groups was similar to that established for normal Korean infants. Human milk zinc concentrations declined as lactation progressed. Zinc concentrations in all formulas tested in this study were higher than HM and were also higher than those claimed by the manufacturers. During the first twelve months, mean serum zinc concentrations of infants were similar in all groups, although infants in the HM group consistently had the lowest zinc intake among the groups, and the overall zinc intake in infants fed SBF was highest. This finding could be explained by the difference zinc bioavailability of HM and formulas. In conclusion, infants fed HM, CBF or SBF has normal growth up to three years of age, although HM contained the lowest zinc concentration followed by CBF, then SBF.

An Adaptive Setting Method for the Overcurrent Relay of Distribution Feeders Considering the Interconnected Distributed Generations

  • Jang Sung-Il;Kim Kwang-Ho;Park Yong-Up;Choi Jung-Hwan;Kang Yong-Cheol;Kang Sang-Hee;Lee Seung-Jae;Oshida Hideharu;Park Jong-Keun
    • KIEE International Transactions on Power Engineering
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    • v.5A no.4
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    • pp.357-365
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    • 2005
  • This research investigates the influences of distributed generations (DG), which are interconnected to the bus by the dedicated lines, on the overcurrent relays (OCR) of the neighboring distribution feeders and also proposes a novel method to reduce the negative effects on the feeder protection. Due to the grid connected DG, the entire short-circuit capacity of the distribution networks increases, which may raise the current of the distribution feeder during normal operations as well as fault conditions. In particular, during the switching period for loop operation, the current level of the distribution feeder can be larger than the pickup value for the fault of the feeder's OCR, thereby causing the OCR to perform a mal-operation. This paper proposes the adaptive setting algorithm for the OCR of the distribution feeders having the neighboring dedicated feeders for the DG to prevent the mal-operations of the OCR under normal conditions. The proposed method changes the pickup value of the OCR by adapting the power output of the DG monitored at the relaying point in the distribution network. We tested the proposed method with the actual distribution network model of the Hoenggye substation at the Korea Electric Power Co., which is composed of five feeders supplying the power to network loads and two dedicated feeders for the wind turbine generators. The simulation results demonstrate that the proposed adaptive protection method could enhance the conventional OCR of the distribution feeders with the neighboring dedicated lines for the DG.

A Study on Logconductivity-Head Cross Covariance in Two-Dimensional Nonstationary Porous Formations (비정체형 2차원 다공성 매질의 대수투수계수-수두 교차공분산에 관한 연구)

  • 성관제
    • Water for future
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    • v.29 no.5
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    • pp.215-222
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    • 1996
  • An expression for the cross covariance of the logconductivity and the head in nonstationary porous formation is obtained. This cross covariance plays a key role in the inverse problem, i.e., in inferring the statistical characteristics of the conductivity field from head data. The nonstationary logconductivity is modeled as superposition of definite linear trend and stationary fluctuation and the hydraulic head in saturated aquifers is found through stochastic analysis of a steady, two-dimensional flow. The cross covariance with a Gaussian correlation function is investigated for two particular cases where the trend is either parallel or normal to the head gradient. The results show that cross covariances are stationary except along separation distances parallel to the mean flow direction for the case where the trend is parallel to head gradient. Also, unlike the stationary model, the cross covariance along distances normal to flow direction is non-zero. From these observations we conclude that when a trend in the conductivity field is suspected, this information must be incorporated in the analysis of groundwater flow and solute transjport.

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A STUDY OF GOLDEN PROPORTION APPLICATION IN KOREAN NORMAL DENTITION (조화된 치열의 황금분할에 관한 연구)

  • Ryu, Seong-Hee;Chung, Kyu-Rhim
    • The korean journal of orthodontics
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    • v.17 no.1
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    • pp.93-106
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    • 1987
  • The purpose of this study was to investigate the fittness of Golden relation items was advocated by Ricketts whether or not it is applicable to the young adult Korean dentitions and also to evaluate the several new Golden relation items conducted by the author. The material was consisted of 81 dental casts (34 male, 47 female) with ideal occlusion, which never undergone orthodontic, prosthodontic procedures. Measurements were made on the arch dimensions using sliding caliper (Mitutoyo. Co) and data were computerized and analyzed. The findings of this study were as follows, 1. The Golden proportion advocated by Ricketts dose not seem to directly applicable to the Korean normal dentition, however, the modification from the Ricketts' original shows the Golden proportion as follow: A first series of progressive Golden relations was found on the Golden ratio among the lower central incisors width, the inter mesioincisal width of the upper lateral incisors, and the upper first premolars width. A second series was found on the Golden ratio among the lower lateral incisors width, lower inter canine tips width and theupper first molar distal cusp tips width. A third series was found on the Golden ratio between the inter distal aspect width of e lower canine and the mesial cusp tips width of the lower second molars or inter cusp tips width of upper second premolars. 2. In addition to Ricketts' original, 4 new Golden proportions were found in young adult Korean dentition, these are as follows; The tips of lower canine width had Golden relation with the width of the upper first premolar buccal cusp tips or the width of the lower first molar central fossae. The distal aspect of the lower first premolars had Golden relation with the buccal surface widths of the lower or upper second molars. The width of upper lateral incisors had Golden relation with the upper second molar height. The width of the lower canine tips had Golden relation with the lower second molar height.

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Effects of Keonbodan (健步丹) on MIA-Induced Osteoarthritis in Rat (건보단(健步丹)이 MIA로 유도된 골관절염 Rat에 미치는 영향)

  • Lee, Eun-Jung;Oh, Min-Seok
    • Journal of Korean Medicine Rehabilitation
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    • v.24 no.2
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    • pp.51-64
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    • 2014
  • Objectives This study was carried out to know the effects of Keonbodan (hereinafter referred to KBD) in osteoarthritis induced by Monosodium iodoacetate(hereinafter referred to MIA) on Wistar rat. Methods Osteoarthritis was induced by injection of MIA into left knee joint cavities of rat. Osteoarthritis rats were divided into 4 groups (normal (n=6), control (n=6), indomethacin (n=6), KBD (n=6) group). The control group was administered normal saline and indomethacin group was administered indomethacin (2 mg/kg). And the KBD group was administered KBD (142 mg/kg). Each groups were administered by orally for 4 weeks. This experiment were carried out in vivo. In vivo, at the end of the experiment (5 weeks after MIA injection), effects on hepatotoxicity and nephrotoxicity, cytokines in serum, arachidonic acid, osteocalcin, MMP-9, TIMP-1 and cartilage volume were evaluated. And histopathological examinations on the articular structures of knee joints were performed. Results 1. In weight-bearing measurement, level of weight was increased. 2. In order to hepatotoxicity and nephrotoxicity, ALT, AST, BUN and creatinine were tested. And there were no significant changes. 3. In serum, levels of TNF-$\alpha$, IL-$1{\beta}$ were significantly decreased. IL-6 was insignificantly decreased. 4. In serum, level of MMP-9 and TIMP-1 was decreased. 5. In serum, level of $LTB_4$, $PGE_2$ and osteocalcin was decreased. 6. In ${\mu}$CT-arthrography, the cartilage volume was greater than that of the control group. 7. The joint damage induced by osteoarthritis was lesser than the control group in histopathologic observation (H&E, Safranin-O staining). Conclusions These results demonstrated that KBD suppressed the osteoarthritis- inducing effects of MIA in rat. And further studies are required to find out more effective substance and anti-osteoarthritic mechanism in the future.

Promoter Methylation Status of Two Novel Human Genes, UBE2Q1 and UBE2Q2, in Colorectal Cancer: a New Finding in Iranian Patients

  • Mokarram, Pooneh;Shakiba-Jam, Fatemeh;Kavousipour, Soudabeh;Sarabi, Mostafa Moradi;Seghatoleslam, Atefeh
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.18
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    • pp.8247-8252
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    • 2016
  • Background: The ubiquitin-proteasome system (UPS) degrades a variety of proteins which attach to specific signals. The ubiquitination pathway facilitates degradation of damaged proteins and regulates growth and stress responses. This pathway is altered in various cancers, including acute lymphoblastic leukemia, head and neck squamous cell carcinoma and breast cancer. Recently it has been reported that expression of newly characterized human genes, UBE2Q1 and UBE2Q2, putative members of ubiquitin-conjugating enzyme family (E2), has been also changed in colorectal cancer. Epigenetics is one of the fastest-growing areas of science and nowadays has become a central issue in biological studies of diseases. According to the lack of information about the role of epigenetic changes on gene expression profiling of UBE2Q1 and UBE2Q2, and the presence of CpG islands in the promoter of these two human genes, we decided to evaluate the promoter methylation status of these genes as a first step. Materials and Methods: The promoter methylation status of UBE2Q1 and UBE2Q2 was studied by methylation-specific PCR (MSP) in tumor samples of 60 colorectal cancer patients compared to adjacent normal tissues and 20 non-malignant controls. The frequency of the methylation for each gene was analyzed by chi-square method. Results: MSP results revealed that UBE2Q2 gene promoter were more unmethylated, while a higher level of methylated allele was observed for UBE2Q1 in tumor tissues compared to the adjacent normal tissues and the non malignant controls. Conclusions: UBE2Q1 and UBE2Q2 genes show different methylation profiles in CRC cases.

Multi-flexible Dynamic Modeling and Wheel Load Analysis of a Rubber Tired Gantry Crane in Container Cargo Working (컨테이너 하역작업 시 갠트리 크레인의 유연다물체 동역학 모델링 및 윤하중 해석)

  • Kim, Jungyun;Kim, Jingon
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.27 no.5
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    • pp.379-384
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    • 2014
  • This article describes the dynamic behaviors of a rubber tired gantry crane(RTGC) under typical load conditions which are used in the design of gantry cranes. In order to investigate the dynamic characteristics of an RTGC, we developed a finite element crane model for its huge structure. The finite element model was validated with the modal test results, e.g., natural frequencies and normal modes. And other components of RTGC were converted into detailed 3D CAD models and finally transformed to rigid body models in a dynamic simulation program ADAMS. The load conditions considered in this paper were a normal operating condition(OP1) and container hanging condition with no external loads. As a result, we could find there was large influence of crane's vibration owing to its structural stiffness and deformation. And the vibration of crane could made the movements of RTGC, which occurs crash or malfunction of crane works.

A Study on Knowledge and Attitude of a Group of Regional University Students (가족보건에 대한 지식 및 태도에 관한 조사연구 (일부 지방대학생을 중심으로))

  • 박선섭
    • Korean Journal of Health Education and Promotion
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    • v.2 no.1
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    • pp.81-92
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    • 1984
  • To find out the amount of knowledge and the attitude which a group of students attending local universities have toward family health, I distributed 690 questionaires to three local universities which I chose. I arrived at the following conculsion after 628 questionnairs were returned. 1) 431 male students(89.8%) and 126 femals students (86.2%) felt that family health science is important enough to be part of the cirriculum. 2) 374 male students (74.5) and 132 female students (90.4%) answered that they get a basic knowledge of health and disease through massmedia. 3) Should an information bureau for health and diseare be retup, 369 students(63.2%) answered that they would join information bureau. 4) In regard to a basic knowledge of health, the report says that 419 ma1e students(83.4%) and 117 female students(80%) don't know about Blood pressure, and 422 male students(84%) and 124 female students (84.9%) don't know about normal pulse and 467 male students(93%) and 128 femal stdents(87.6%) don't know about normal respiration. 5) In regard to communicable disese, 186 male students(37.1%) and 61 female students(41.7%) have a basic knowledge of these disease. In regard to diseases which commonly afflict the eldrly, 157 male students (31.2%) and 62 female students (42.4%) have a basic knowledge of these diseases. In regard to other diseases, the finding of this report are that on the average male students(74.6%) and female students of(73.4%) don't have a basic knowledge of family health. 6) 182 male students (36.2%) and 50 female students (34.2%) anwered that the way to promote health and prevent disease is to have a medical examination regularly and also 142 male students (28.2%) and 33 female students(22.6%) answered that it is necessary to have knowledge about how to keep health. 7) 254 male students (50.4%) and 90 female students (61.6%) said that when they are sick they depend on help from the pharmacist.

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THE STUDY OF THE EFFECT OF DENTAL ARCH FROM ON CHEWING MOVEMENT I. THE PROSTHETIC CONSIDERATIONS ABOUT THE CLASSIFICATION OF DENTAL ARCH FORM (저작운동에 미치는 치열궁형태의 영향에 관한 연구 I. 치열궁형태의 분류에 대한 보철학적 검토에 대하여)

  • Jo Byung-Woan;Chang Heun-Soo;Kim Jong-Pil;Ahn Sang-Hun;Ahn Jae-Jin
    • The Journal of Korean Academy of Prosthodontics
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    • v.32 no.3
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    • pp.431-443
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    • 1994
  • As the dental arch is the curve connecting the cusp tip of tooth, the dental arch form, composing of the occlusion, is one the important factors of occlusal reconstruction. Many studies about the horizontal dental arch form have been reported, but until now, it is unclear to infer the position of the teeth in dental arch form, to evaluate the effect of the horizontal dental arch form on chewing movement. The purpose of this study is to make objective criteria to infer the position of the teeth in dental arch. In this study, 100 subjects with individdual normal occlusion were evaluated. By multiple regression analysis on the basis of the relation of the canine and the first molar, the positions of teeth in dental arch were inferred. According to buccolingual relationship of maxillary to mandibular posterior teeth, the dental arch forms were classified into five groups, i, e. the normal group, the group which the maxillary second molar positions buccal side, the group which the maxillary premolars position buccal side, the group which the maxillary premolar position lingual side. From the results, objective criterial to infer the positons of the first premolar, the second premolar, the second molar in dental arch were made.

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DECAY OF TURBULENCE IN FLUIDS WITH POLYTROPIC EQUATIONS OF STATE

  • Lim, Jeonghoon;Cho, Jungyeon
    • Journal of The Korean Astronomical Society
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    • v.53 no.2
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    • pp.49-57
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    • 2020
  • We present numerical simulations of decaying hydrodynamic turbulence initially driven by solenoidal (divergence-free) and compressive (curl-free) drivings. Most previous numerical studies for decaying turbulence assume an isothermal equation of state (EOS). Here we use a polytropic EOS, P ∝ ργ, with polytropic exponent γ ranging from 0.7 to 5/3. We mainly aim at determining the effects of γ and driving schemes on the decay law of turbulence energy, E ∝ t. We additionally study probability density function (PDF) of gas density and skewness of the distribution in polytropic turbulence driven by compressive driving. Our findings are as follows. First of all, we find that even if γ does not strongly change the decay law, the driving schemes weakly change the relation; in our all simulations, turbulence decays with α ≈ 1, but compressive driving yields smaller α than solenoidal driving at the same sonic Mach number. Second, we calculate compressive and solenoidal velocity components separately and compare their decay rates in turbulence initially driven by compressive driving. We find that the former decays much faster so that it ends up having a smaller fraction than the latter. Third, the density PDF of compressively driven turbulence with γ > 1 deviates from log-normal distribution: it has a power-law tail at low density as in the case of solenoidally driven turbulence. However, as it decays, the density PDF becomes approximately log-normal. We discuss why decay rates of compressive and solenoidal velocity components are different in compressively driven turbulence and astrophysical implication of our findings.