• Journal of Photoscience
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• v.9 no.2
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• pp.457-459
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• 2002

Sunlight causes various types of adverse skin changes on the sun-exposed areas of the skin, in which the most hazardous one is the induction of malignant skin tumours. FT -IR spectra were obtained from specimens excised from normal skin, BCCs, SCCs, MMs, nevi, lesions of solar keratosis and Bowen's disease. Tissue samples from freshly frozen specimens were cut into 2 sections in strictly sequential order to be stained with H & E for histopathological analysis, and then to be air-dried on CaF$_2$ slide glasses for further spectral data acquisition from defined area of interest. Intra- and inter-sample variations were estimated within grouped lesion categories according to each skin component. Mean spectra for each type of tissue pathology in the 800-1800 $cm^{-1}$ / region was interpreted using the classical group frequency approach that showed the most visible differences in spectra of benign, premalignant and malignant changes directly related to protein conformation and nucleic acid bases. The relative intensity of the nucleic acid peak was increased with progression to malignancy. In addition, PCA was able to evaluate and maximise the differences in the spectra by reducing the number of variables characterizing each patient and pathology category. This type of approach to non-destructively estimate the complexity of IR-spectra of inhomogeneous samples such as skin demonstrates the advantage of FT -IR microspectroscopy to be able to observe diseased states (benign, premalignant, malignant) and distinguish them from normal against a huge background of inter- and intra-subject variability.

• Journal of Families and Better Life
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• v.25 no.5
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• pp.31-46
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• 2007

The purpose of this study was to determine the differences in internet use motivations and problem behaviors among vocational high school students according to internet addiction and family system type. Five hundred vocational high school students from Daegu took part in the survey. The questionnaire survey consisted of an internet addiction self-assessment scale, a family system type scale, an internet use motivation scale, and a problem behavior scale. The data was analysed using MANOVA and Cronbach a, and the $Scheff\acute{e}$ test was used for post-hoc analysis. The major findings of this study were as follows: First, the study found significant differences in adolescent internet use motivation according to internet addiction. Adolescents in the high dangerous user group showed higher communicative, experiential, and addictive motivations than adolescents in potentially dangerous and normal user groups. Also, there were no significant differences in informative motivation according to internet addiction. Regardless of internet addiction, adolescents tend to use the internet to search for information and to solve problems. Second, there were significant differences in adolescents' problem behaviors according to internet addiction. More specifically, adolescents who were in the high dangerous user group displayed more problem behaviors toward their body, family, school, and society than adolescents in the potentially dangerous and the normal user groups. Third, an adolescent's family system type significantly influenced his/her internet use motivation. Adolescents from an extreme family showed higher communicative and addictive motivations than adolescents from middle and balanced families. Fourth, there were significant differences in the problem behaviors of adolescents according to family system types. Adolescents from an extreme family showed more problem behaviors toward their body, family, school, and society than adolescents from middle and balanced families.

• Bulletin of the Korean Chemical Society
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• v.31 no.5
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• pp.1349-1354
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• 2010

The geometries and isomerization of the alkylidene silylenoid $H_2C$ = SiLiF as well as its insertion reactions with R-H (R = F, OH, $NH_2$) have been systematically investigated at the B3LYP/6-311+$G^*$ level of theory. The potential barriers of the three insertion reactions are 97.5, 103.3, and 126.1 kJ/mol, respectively. Here, all the mechanisms of the three reactions are identical to each other, i.e., an intermediate has been formed first during the insertion reaction. Then, the intermediate could dissociate into the substituted silylene ($H_2C$ = SiHR) and LiF with a barrier corresponding to their respective dissociation energies. Correspondingly, the reaction energies for the three reactions are -36.4, -24.3, and 3.7 kJ/mol, respectively. Compared with the insertion reaction of $H_2C$ = Si: and R-H (R = F, OH and $NH_2$), the introduction of LiF makes the insertion reaction occur more easily. Furthermore, the effects of halogen (F, Cl, Br) substitution and inorganic salts employed on the reaction activity have also been discussed. As a result, the relative reactivity among the three insertion reactions should be as follows: H-F > H-OH > H-$NH_2$.

• International Journal of Concrete Structures and Materials
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• v.6 no.2
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• pp.65-78
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• 2012

An experimental study was carried out to evaluate fresh properties of a moderately high-strength (high-flowing) self-compacting concrete (SCC) and to investigate shear behavior and performance of deep beams made with SCC. Fresh and hardened properties of normal concrete (NC) and SCC were evaluated. The workability and compacting ability were observed based on casting time and number of surface cavities, respectively. Four-point loading tests on four deep beams (two made with SCC and two with NC) were then conducted to investigate their shear behavior and performance. Shear behavior and performance of beams having two different web reinforcements in shear were systematically investigated in terms of crack pattern, failure mode, and load-deflection response. It was found from the tests that the SCC specimen having a normal shear reinforcement condition exhibited a slightly higher load carrying capacity than the corresponding NC specimen, while the SCC specimen having congested shear reinforcement condition showed a similar load carrying capacity to the corresponding NC specimen. In addition, a comparative study between the present experimental results and theoretical results in accordance with ACI 318 (Building Code Requirements for Reinforced Concrete (ACI 318-89) and Commentary-ACI 318R-89, 1999), Hsu-Mau's explicit method (Hsu, Cem Concr Compos 20:419-435, 1998; Mau and Hsu, Struct J Am Concr Inst 86:516-523, 1989) and strut-and-tie model suggested by Uribe and Alcocer (2002) based on ACI 318 Appendix A (2008) was carried out to assess the applicability of the aforementioned methods to predict the shear strength of SCC specimens.

• Journal of the Korea Institute of Building Construction
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• v.13 no.3
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• pp.202-208
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• 2013

The method used to test lightweight aggregate concrete for its resistance to freezing and thawing is different in each country. In Korea, the method of KS F 2456 on normal concrete is adopted for lightweight aggregate concrete, while the testing method of ASTM C 330 lightweight aggregates for structural concrete is used in the majority of overseas countries. In this study, we identified differences between KS F 2456 and ASTM C 330 in terms of the testing method for freezing and thawing resistance, and we studied the influence of this on the freezing and thawing resistance of lightweight aggregate concrete. The results of this study were as follows: Blocked lightweight aggregates had a slight collapse of shape and lost weight by repeated freezing and thawing, but unblocked lightweight aggregates were badly collapsed. And while the freezing and thawing resistance tests of normal concrete showed similar results despite the difference in the KS and ASTM testing method, the results for lightweight aggregate concrete were very different. So the KS test method shows evaluation results that are much lower than the ASTM test method.

• Journal of the Korea Fashion and Costume Design Association
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• v.13 no.2
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• pp.47-62
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• 2011

The purpose of this study was to investigate the knitwear preferences and purchase behaviors of university students. The subjects were 493 university students in Daejeon and Chungnam Provinces. The method of this study was a survey and measurement instruments were 34 stimuli which were manipulated pullover patterns and shapes and self-administrated questionnaire with knitwear design preference items and knitwear purchase behavior items. Data were analyzed by factor analysis, frequency analysis, Cronbach'${\alpha}$, t-test, ANOVA and $Sch{\acute{e}}ffe$ test using SPSS program. The results of the study were as follows. First, university students most preferred achromatic colors, pastel tones, solid patterns, and 100% cotton. Second, as for knitwear purchase behaviors, university students considered the esthetical factor to be most important among 4 dimensions (comfortable, esthetical, economical, and conspicuous factors) as important purchase criteria, and they used internet web sites for knitwear purchases. Third, there were significant differences in preferred pullover shape depending on neckline shape, neck depth, sleeve shape and clothing length. University students preferred the classic pullover design with V neckline, normal neck depth, set-in sleeves and normal length. Fourth, university students preferred the cloud motif and riding man motif among the 9 Baekje traditional motifs and one point small pattern on the left chest and crosswise bending pattern for pattern arrangement.

• The Korea Journal of Herbology
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• v.31 no.2
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• pp.13-19
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• 2016

Objectives : The present study was designed to evaluate the protective effect of Allium tuberosum (AT) extract on atherosclerosis in LDL receptor knockout (LDLr KO) mouse fed western diet.Methods : The AT was extracted 70% ethanol. The experimental groups were divided with four groups of LDLr KO mice, one group fed a normal diet and the others fed a Western diets for 8weeks. Two Western diet groups were orally administered AT extract at dosage of 100 and 300 mg/kg body weight. The body weight and food intake were measured every day. We measured levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), triglyceride (TG), total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL), and Glucose in serum. Also, effect of AT extract performed using H&E staining.Results : The AT treatment groups showed decrease in body weight and food efficiency in comparison with control group. Blood biochemistry parameters such as TG, TC, LDL, and glucose levels were increased in control group, while AT treatment groups were reduced. Also, the increased levels of ALT and AST were improved by AT extract. We confirmed that the weights of liver, kidney, subcutaneous fat, epididymal fat, kidney leaf fat, and intraabdominal fat were change in LDLr KO mice treated AT extract. In addition, histopathological changes in liver and aorta were similar to normal group.Conclusions : Based on these results, the AT extract is considered to make prevention of atherosclerosis through reduction and functional improvement of the liver and vascular endothelial cells in the body fat accumulation and lipid content in LDLr ko mouse model.

• Journal of Pharmacopuncture
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• v.17 no.2
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• pp.27-33
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• 2014

Objectives: The main objective of this study was to evaluate the anti-depressant effects of pharmacopuncture using sumsu (Bufonis venenum). Methods: Animals were divided into three groups (control, sham, and experimental), with eight mice per group. The sham and the experimental groups were exposed to 2 hours of immobilization stress daily for 14 days. They were also injected with normal saline (sham) or subjected to pharmacopuncture with sumsu at the acupoints HT7, SP6, and GV20 (experimental). The depression or anxiety-like behaviors of the mice in each group were evaluated 1 day after treatment. Results: There was no difference in locomotor activity between the groups during the open-field test; i.e., all groups had normal motor function. However, the open-field and the forced-swimming tests revealed that depression and anxiety-like behaviors were decreased significantly in the group treated with sumsu pharmacopuncture. Conclusion: Sumsu pharmacopuncture attenuated depressive or anxiety-like behavior in mice stressed with chronic immobilization. These results suggest that sumsu pharmacopuncture has therapeutic potential for treating neuropsychiatric disorders such as anxiety or depression disorder.

• International Journal of Highway Engineering
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• v.16 no.2
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• pp.19-24
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• 2014

PURPOSES : The study objective was to evaluate rheology and physical properties of SBS-modified warm-mix asphalt (WMA) binders in comparison with hot-mix asphalt (HMA) binders. METHODS : Four different SBS polymers were used to prepare polymer-modified asphalt (PMA) binders, and three different warm-mix additives (WAD) were used to prepare a total of 12 WMA PMA binders. The kinematic viscosity was measured at 115, $135^{\circ}C$. The PG was determined using DSR and BBR. The pass/fail (P/F) temperatures for high and low PG grading were evaluated for HMA PMA and WMA PMA binders. RESULTS : PG 76-22 binders could be prepared by modifying the base binder (PG 64-22) using 4.5 wt% of SBS. The kinematic viscosity (KV) of SBS PMA was increased by 3 times higher than that of base asphalt. The SBS PMA with WAD showed 10% lower KV than that of the normal SBS PMA at $115^{\circ}C$ The high P/F temperatures showed almost no difference between HMA PMA and WMA PMA binders. The high P/F temperature showed very high correlations with KV ($R^2$ > 0.97). The result of SBS modification caused increase of low P/F temperature by $2.7^{\circ}C$ on average. CONCLUSIONS : Since the PMA with WAD showed 10% lower KV than normal (HMA) PMA at $115^{\circ}C$, reducing PMA mixture temperature down to a WMA level was possible in this study. The higher KV binders showed the higher P/F temperature. There was almost no change in high P/F temperature due to the use of WAD. The SBS PMA, showing an increased low P/F temperature, might show somewhat poorer performance at low-temperature, even though the lower PG grade was staying at the same level, i.e., $-22^{\circ}C$.

• Journal of Acupuncture Research
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• v.33 no.2
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• pp.35-49
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• 2016

Objectives : This study was designed to investigate the anti-osteoarthritic effects of clematidis radix pharmacopuncture on the MIA-induced osteoarthritis rats. Methods : The subjects were divided into 4 groups ; Normal rat group(N, n=5), MIA-induced osteoarthritis control rat group(C, n=5), MIA-induced osteoarthritis rat group injected with normal saline at ST36(NS, n=5), and MIA-induced osteoarthritis rat group injected with clematidis radix pharmacopuncture at ST36(CR, n=5). The experiment was conducted over a period of 21 days after injecting MIA. We analyzed body weight, hind paw weight distribution, liver and renal function, immunocytes, cykokines, inflammatory mediators, inflammatory proteins and mRNA expressions, as well as histopathological changes. Results : The CR group showed a significant increase in the hind paw weight distribution, and significant decreases in IL-$1{\beta}$, IL-6, $PGE_2$, $LTB_4$, osteocalcin, deoxypyridinoline level, the protein expression of COX2, arachidonate 5 lipoxygenase, and the mRNA expression of COX2, TNF-${\alpha}$, IL-$1{\beta}$, and NOS-II. In terms of the joint damages induced by osteoarthritis, the CR group showed a greater protective effect than group C in histopathologic observation (H&E, Safranin-O staining). Conclusion : These results demonstrated that clematidis radix pharmacopuncture had anti-inflammatory and analgesic effects. In addition, these results showed that it inhibited the progression of osteoarthritis.