• The Journal of Engineering Geology
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• v.29 no.4
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• pp.461-468
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• 2019

Gamma-radiation dose rates were measured at 77 points around the Ogcheon lower phyllite zone (og2) in Goesan County, Korea, using gamma-ray spectrometry. Sample K contents were in the range 1.8-8.8% (average 4.6%), highest in Kgr. The eU contents were 0.2-217.9 ppm (average 16.7 ppm), highest in og2 (median 29.6 ppm). The eTh contents were 11.9-76.5 ppm (average 29.5 ppm) and the average eTh content of Kgr was 45.4 ppm, higher than those of Ogcheon meta-sedimentary rocks (og1, og2, and og3) (26.6-30.6 ppm). Except for some high-uranium sites in og2, ⁴⁰K is the main radioactive material contributing to the gamma-radiation dose in the study area. Our results indicate that the outdoor effective dose rate of the area is 0.08-1.71 mSv y^-1 (average 0.28 mSv y^-1), with most areas apart from three points in og2 displaying dose rates <1 mSv y^-1, which is the normal natural radiation background level.

• Journal of Veterinary Clinics
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• v.31 no.2
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• pp.95-101
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• 2014

Five dogs were used to determine whether 0.1% tacrolimus ointment application for one day would inhibit IgE-mediated late-phase reactions (LPRs). It was consisted of three periods: one period without therapeutic administration (control) and two periods of treatment with either the tacrolimus ointment or vehicle. Induction of IgE-mediated LPRs was induced by intradermal injections of 0.05 ml (0.14 mg/ml) of solution of goat anti-canine IgE polyclonal antibodies. Each section for mast cells (MCs) and eosinophils (EPs) was stained with acidified toluidine blue, and Luna's stain, respectively. Assessment of anti-inflammatory effect of tacrolimus ointment composed of cell counts of MC and EP from lesions of induced LPR. In normal canine biopsies, the number of dermal MCs and EPs were $12.3{\pm}1.4cells/mm^2$ and $3.1{\pm}1.3cells/mm^2$, respectively. MC counts dramatically decreased at time dependent manner after anti-IgE administration. However, the number of MCs on 6 hours after challenge was significantly less decreased in the groups treated with the tacrolimus, as compared with control and vehicle group. The number of EPs on 24 hours after challenge was significantly lower in the group treated with the tacrolimus than in the control and vehicle groups. In conclusion, this study revealed that 0.1% tacrolimus ointment in dogs may exert a potent anti-inflammatory effect on inhibition of MC degranulation and also secondary prevention of EP infiltration during LPR.

• Asian-Australasian Journal of Animal Sciences
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• v.17 no.8
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• pp.1158-1161
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• 2004

This study chiefly aims to ascertain the effect of birth weight and litter size on productive performance in rabbits. After delivery kits were removed from their mothers for individual weighing and randomly assigned to one of the following three experimental treatments: Group (KT 6) with six tiny kits (about 45 g) per litter (21 litters); Group (KT 8) with eight tiny kits (about 45 g) per litter (17 litters); Group (KN8) with eight normal kits (about 70 g) per litter (20 litters). The litters, separated from their mothers by putting them in a closed cage, suckled one time a day for 15 minutes. Daily milk production was measured by weighing the does immediately before and after suckling; body weight of kits was measured on a weekly basis. At weaning 60 rabbits per group were raised for six weeks to ascertain post-weaning performance and health. Compared with the two other groups, the kits of group KT8 ingested smaller quantities of milk both during the first 3 weeks (497.7 vs. 520.0 vs. 544.3 g, respectively for groups KT8, KN8, KT6) and the following period (261.3 vs. 285.0 vs. 302.7 g, respectively for KT8, KN8, KT6). The differences between groups KT8 and KT6 were statistically significant (p<0.01) in the first period while in the second period also KN8 group showed milk intake different in respect of KT8 (p<0.01) and KT6 (p<0.05) groups. Solid feed intake was significantly (p<0.05) lower in group KT6 (23.1 vs. 26.2 vs. 26.8 g/d, respectively for groups KT6, KN8, KT8). At weaning the kits of group KN8 always weighed more (966 vs. 894 vs. 888 g; p<0.01, respectively for groups KN8, KT6, KT8). After weaning, no parameter considered (daily weight gain, feed intake, feed conversion ratio, mortality and risk sanitary index) was affected by birth weight and litter size.

• Journal of Korean Academy of Nursing
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• v.28 no.4
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• pp.893-907
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• 1998

The purpose of this study was to determine the effect of regular exercise during dexamethasone injection on the body weight, weight of hindlimb muslces, myofibrillar protein content and glutamine synthetase activity. 180-200g female Wistar rats were divided into four groups : control, exercise, dexamethasone injection (dexa), and exercise during dexamethasone injection(D+E) group. The dexa group received daily subcutaneous injection of dexamethasone at a dose of 4mg/kg body weight for 7 days. The exercise group ran on a treadmill for 60min/day(20minutes every 4 hours) at 10m/min and a 10$^{\circ}$grade. The control group received daily subcutaneous injection of normal saline at a dose of 4mg/kg body weight for 7 days. The D+E group ran on a treadmill for 60min/day(20minutes every 4 hours) at 10m/min and a 10$^{\circ}$ grade during dexamethasone injection. Body weight of the control group increased significantly from days of experiment, that of the dexa group decreased significantly from day 4 of the experiment resulting in a 82.4% decrease compared to the first day of the experiment. Body weight of the D+E group decreased significantly from day 5 of experiment resulting in a 81.77% decrease comprared to the first day of the experiment. Body weights, muscle weight and myofibrillar protein content of the plantaris and gastrocnemius decreased significantly and muscle weight of the soleus tended to decrease with dexamethasone injection. Glutamine synthetase activity of the hindlimb muscles increased significantly with the dexamethasone injection. The relative weight of the soleus was comparable to the control group and that of plantaris decreased significantly and that of gastrocnemius tended to decrease compared to that of the control in the dexa group. Body weight and muscle weight of the plantaris and gastrocnemius of the excrcise group were comparable to the control group, and the muscle weight of soleus showed a tendencey to increase. The relative weight of the soleus increased significantly and that of the plantaris and gastrocnemius were comparable to the control in the exercise group. Myofibrillar protein content of the soleus and plantaris increased significantly and there was no change of GS activity of the hindlimb muscles compared to the control in the exercise group. Body weight of the D+E group was comparable to the dexa group, muscle weight of the plantaris increased significantly and that of the soleus and gastrocnemius showed a tendency to increase. The relative weight of the hindlimb muscles increased significantly. Myofibrillar protein content of the soleus and plantaris increased significantly and that of the gastrocnemius tended to increase compared to the dexa group. Body weight and muscle weight of the plantaris and gastrocnemius of the D+E group did not recover to that of the control group. Muscle weight of the soleus recovered to that of the control group. The relative weight and of myofibrillar protein content of the hindlimb muscles recovered to that of the control group. From these results, it is suggested that regular exercise during dexamethasone injection might attenuate the muscle atrophy of the hindlimb muscles.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.11
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• pp.4781-4786
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• 2015

Siberian ginseng (Eleutherococcus senticosus) is used primarily as an adaptogen herb and also for its immune stimulant properties in Western herbal medicine. Another closely related species used in East Asian medicine systems i.e. Kampo, TCM (Manchuria, Korea, Japan and Ainu of Hokkaido) and also called Siberian ginseng (Acanthopanax senticosus) also displays immune-stimulant and anti-cancer properties. These may affect tumour growth and also provide an anti-fatigue effect for cancer patients, in particular for those suffering from lung cancer. There is some evidence that a carbohydrate in Siberian ginseng may possess not only immune stimulatory but also anti-tumour effects and also display other various anti-cancer properties. Our study aimed to determine the inhibitory and also proliferative effects of a methanol plant extract of Siberan ginseng (E. senticosus) on various cancer and normal cell lines including: A-549 (small cell lung cancer), XWLC-05 (Yunnan lung cancer cell line), CNE (human nasopharyngeal carcinoma cell line), HCT-116 (human colon cancer) and Beas-2b (human lung epithelial). These cell lines were treated with an extract from E. senticosus that was evaporated and reconstituted in DMSO. Treatment of A-549 (small cell lung cancer) cells with E. senticosus methanolic extract showed a concentration-dependent inhibitory trend from $12.5-50{\mu}g/mL$, and then a plateau, whereas at 12.5 and $25{\mu}g/mL$, there is a slight growth suppression in QBC-939 cells, but then a steady suppression from 50, 100 and $200{\mu}g/mL$. Further, in XWLC-05 (Yunnan lung cancer cell line), E. senticosus methanolic extract displayed an inhibitory effect which plateaued with increasing dosage. Next, in CNE (human nasopharyngeal carcinoma cell line) there was a dose dependent proliferative response, whereas in Beas-2 (human lung epithelial cell line), an inhibitory effect. Finally in colon cancer cell line (HCT-116) we observed an initially weak inhibitory effect and then plateau.

• Korean Journal of Acupuncture
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• v.30 no.4
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• pp.264-271
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• 2013

Objectives : To observe the changes in the expression of neurotransmitters NO and enzymes that create NO, such as nNOS, iNOS and eNOS, upon the needle insertion on river point, one of the five transport points of three yang meridians on the forefoot. Methods : Based on rats, needle was inserted on both sides of LI5, SI5 and TE6, which are river points of three yang meridians on the forefoot, and were retained for five minutes. After the retention, blood was drawn via cardiac puncture and tissues from each point around meridian vessels were extracted to be examined on the changes of the expression of NO, as well as of nNOS, iNOS and eNOS. Results : In terms of the effect on NO creation in tissues, none of the experimental groups showed any significant change compared to the Normal group. In terms of the effect on expression of nNOS within tissues, LI5 and SI5 showed significant increase based on the results of immunohistochemistry. In iNOS within tissues, LI5 and SI5 showed significant increase based on the results of immunohistochemistry. In eNOS within tissues, SI5 showed significant increase based on the results of immunohistochemistry. Conclusions : The effect on the function of NO, nNOS, iNOS and eNOS of needle insertion on the river points of three yang meridians on the forefoot could be observed, and based on this study, it is considered that the effect of needle stimulation on the changes of nervous system could be found out through additional research.

• Economic and Environmental Geology
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• v.34 no.1
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• pp.119-131
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• 2001

A mean characteristic remanent magnetization was obtained for the first time in Korea from volcanic and pyroclastic sedimentary rocks distributed in Haenam Area, located in southwestern part of the Korean Peninsula. The age of the prevailing rocks in this area belongs mostly to Late Cretaceous, with a few exceptions of Early Cretaceous, mainly based on K/Ar whole rock age dating. Characteristic remanent magnetizations of these have both normal and reverse polarities with antipodal direction, which were interpreted to be the primary remanent magnetizations obtained by the ambient Earth's magnetic field at the time of formation of the concerned rocks. The source magnetic minerals of the remanent magnetization has been identified as magnetite. The mean direction of characteristic remanent magnetization obtained from the Late Cretaceous rocks in this study is Dm/Im=21.4 supper(o)/57.1 supper(o) (${\alpha}_{95}=13.4^{\circ}$, k=350.0). The paleomagnetic pole position calculated from this result for the Late Cretaceous, is $72.5^{\circ}N/199.9^{\circ}E$ (dp/dm= $14.2^{\circ}/19.5^{\circ}E$), which matches well with those of 80 Ma ($76.2^{\circ}N/198.9^{\circ}E$) and 90 Ma ($76.2^{\circ}N/200.1^{\circ}E$) of the Eurasian Continent's APWP (Apparent Polar Wander Path). This result strongly indicates that the studied area, belonging to the Eurasian Continent, have suffered very little geotectonic movement after the Late Cretaceous. The deflection of declination of remanence from Early Cretaceous rocks in the study area may indicate that the micro-block was counterclockwisely rotated with vertical axis between the late of Early Cretaceous and the early of Late Cretaceous.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.24 no.6
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• pp.644-653
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• 2013

In this paper, a formulation for obliquely incident electromagnetic wave has been presented for an analysis of highpower electromagnetic pulse penetration into multilayered dispersive media. Based on generalized models of measured dielectric constants and propagation channels reflecting the Earth's general features, the propagation phenomenon of the obliquely incident early-time(E1) high altitude electromagnetic pulse(HEMP) is analyzed. In addition, the polarization and critical angle are also considered. It is found that the total reflection occurs at an incident angle of about 38 degrees at the soil-rock interface, and that the parallel-polarized E1 HEMP penetrates better than the perpendicular-polarized one. The peak level of the penetrating electric field is found to be 5.6 kV/m at normal incidence, regardless of the type of polarization, and E1 HEMP is greatly reduced near the critical angle. Moreover, the penetrating E1 HEMP is analyzed as a variation of moisture content and depth of materials, resulting E1 HEMP could be useful in determining the levels of shielding required for buried facilities.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.59 no.3
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• pp.239-244
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• 2014

Barnyard grasses are dominant weed that are not eliminated easily in the direct water seeding cultivation. So, deep water treatment can reduce their growth at the early growing stage of submerged paddy. This study was carried out to investigate the reducing growth of the barnyard grasses through flooding at seedling stages of rice plant in the green house. Under the normal condition, the plant height of rice variety, Samgwangbyeo, and 3 species of barnyard grass, E. caudata, E. pratocola and E. utilis were not showed the difference up to 10 days after seeding while the plant height of 3 barnyard grass species, especially E. utilis, was more elongated than the rice at 25 days after seeding. Plant height of the 3 barnyard grasses were not elongated largely during 3, 5 and 7 days of flooding treatment at 10 days after seeding. Interestingly, the rice seedlings was grown over 20 cm, and the flooding tolerance of rice seedling was higher than the 3 barnyard grass varieties. However, after flooding treatment for 3, 5 and 7 days, the elongation of plant height of 3 barnyard grasses, especially E. utilis was more speedy compared to rice seedlings as 6 to 9 days passes. And the protein spots from barnyard grasses were also reduced and eliminated more than the spots of rice seedling after flooding treatment.

• Korean Journal of Veterinary Research
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• v.36 no.3
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• pp.709-718
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• 1996

This experiment was carried out to clarify the effect of lead poisoning on the lead and essential trace elements homeostasis of tissues in rats. Fifty female Wistar rats, 7 weeks old, were divided into four experimental groups(B, C, D, and E) and a control(A). The four experimental groups received diets contaminated artificially with 10 (B group), 100 (C group), 1,000 (D group) and 5,000 (E group) ${\mu}g/g$ of lead as lead acetate, respectively. The control group received normal diet. Rats were necropsied on the 4th or 8th week of experimental periods and heart, liver, spleen, kidney, muscle, lung and hair were taken. The tissues were analysed for lead, copper, zinc, iron and calcium content by atomic absorption spectrophotometry. From these experiments following results ware obtained ; In C group, lead content of the heart, liver, kidney and hair were significantly increased both on the 4th and 8th week of experiment. In D and E group, lead content of all tissues including heart, liver, spleen, kidney, muscle, hair and lung were significantly increased in accordance with the lead contamination both on the 4th and 8th week of experiment. In C group, copper content of tissues were significantly increased in the heart, liver, kidney and lung on the 4th week and all tissues on the 8th week of experimental periods. In D and E group, copper content of the liver were significantly increased both on the 4th and 8th week of experiment. But the copper content of tissues were gradually decreased compared with C group in accordance with the lead contamination. Especially the content in spleen, heart or kidney were significantly decreased compared with the control group. The zinc content of kidney, heart, or spleen were decreased in D and E groups whereas the iron and calcium content showed no significant change.