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Long-term radiographic evaluation of GTR treatment in intrabony defect (골연하 결손부에서 조직유도재생술의 장기적 방사선학적 변화 관찰)

  • Choi, Mi-Hye;Park, Jin-Woo;Suh, Jo-Young;Lee, Jae-Mok
    • Journal of Periodontal and Implant Science
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    • v.37 no.2
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    • pp.181-192
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    • 2007
  • Periodontal surgery as part of the treatment of periodontal disease is mainly performed 1) to gain access to diseased areas for adequate cleaning; 2) to achieve pocket reduction or elimination; and 3) to restore the periodontal tissues lost through the disease; i.e., a new attachment formation of periodontal regeneration. To accomplish the latter, often referred to as the ultimate goal of periodontal therapy, a number of surgical procedures have been advocated throughout the years. Clinical studies have demonstrated that considerable gain of clinical attachment and bone can be achieved following guided tissue regeneration (GTR) therapy of intrabony defects. The aim of this study was to analyse the radiographic bone changes 2-year after GTR using a bone graft material and nonresorbable membrane. Patients attending the department of periodontics of Kyungpook National University Hospital were studied. Patients had clinical and radiographic evidence of intrabony defect(s), 33 sites of 30 patients aged 32 to 56 (mean age 45.6) were treated by GTR with a bone graft material and nonresorbable membrane. Baseline and 2-year follow-up radiographs were collected and evaluated for this study. Radiographic assessment includes a bone fill, bone crest change, defect resolution, and % of defect resolution. Pre- and post-treatment differences between variables (maxilla and mandible, defect depth, defect angle, bone graft materials) using the paired t-test were examined. We observed $2.86{\pm}1,87mm$ of bone fill, $065{\pm}0.79mm$ of crestal resorption, $3.49{\pm}2.11mm$ of defect resolution, and $44.42{\pm}19.51%$ of percentage of defect resolution. Mandible, deeper initial defect depth, narrower initial defect angle showed greater bone fill, defect resolution, and % of defect resolution. But no difference was observed between xenograft and allograft. Outcome of GTR as a therapy of intrabony defect was better than other therapy, but herein, good oral hygiene maintenance as a anti-infective treatment and periodic recall check of patients are essential.

An External Costs Assessment of the Impacts on Human Health from Nuclear Power Plants in Korea (국내원전운전(國內原電運轉)에 따른 보건영향(保健影響)의 외부비용평가(外部費用評價))

  • Kim, Kyoung-Pyo;Kang, Hee-Jung
    • Journal of Radiation Protection and Research
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    • v.33 no.2
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    • pp.67-76
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    • 2008
  • As the first comprehensive attempt at a national implementation, this study aims at assessing the external costs of major electricity generation technologies in Korea, particularly an evaluation of the impacts on human health resulting from exposures to atmospheric radiological emissions from nuclear power plants, and a monetary quantification of their damages. The methodology used for the assessment of the externalities of the selected fuel cycles has been developed by the International Atomic Energy Agency (IAEA), namely the SimPacts Model Package. The model is internationally recognized as a tool which can be applied to a wide range of fuels, different technologies and locations, for an externalities study. In this study, the relevant emissions are quantified first and then their impacts on human health are evaluated and compared. The study focused on all the nuclear power plants for the last 6 years ($2001{\sim}2006$) in Korea. With respect to nuclear power, the impact analysis only focuses on a power generation, however the front- and back-end nuclear fuel cycles are not included, namely uranium mining, conversion, enrichment, reprocessing, conditioning, etc., because these facilities are not present in Korea. The analysis results show that nuclear power in general, generates low external costs. The highest damage costs from the nuclear power plants among the 4 sites in Korea were estimated to be 3.9 mills/MWh, which is about 1/20th of the result for a similar case study conducted in the U.K., implemented through the ExternE project. This difference is largely due to the number of radionuclides included in the study and the amount of released radioactive emissions based on up-to-date information in Korea. In this study, the sensitivities of the major factors for nuclear power plants were also calculated. The analysis indicates that there was around a ${\pm}3%$ damage costs variation to a ${\pm}15%$ change of the reference population density and a ${\pm}1%$ damage cost variation to a $1{\sim}30$ meters change of the effective release height, respectively. These sensitive calculations show that there is only a minor difference when the reference costs are compared.

A Laboratory Study on Erosional Properties of Fine Cohesive Sediments from Saemankeum Artificial Lake (새만금 인공호 점착성 퇴적물의 침식특성에 대한 실험적 연구)

  • Hwang, Kyu-Nam;Kim, Hyun-Min;Ahn, Ik-Jang
    • Journal of Korea Water Resources Association
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    • v.41 no.5
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    • pp.473-482
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    • 2008
  • The purpose of this study is to quantitatively estimate the erosional properties for cohesive sediment from Saemankeum artificial lake. A series of erosion tests were conducted with Chonbuk annular flume, which is the first one constructed in this country and verified with validities. Each erosion tests were conducted under a uniform bed condition but a different bed density respectively, and its critical shear stress for erosion(${\tau}_{ce}$) as well as the erosion rate coefficient (${\varepsilon}_M$) were determined quantitatively. Since the erosional properties of the cohesive sediments vary largely depending in the physico-chemical properties, such properties of Saemankeum sediments were also estimated and their effects on the erosional properties were analyzed. For Saemankeum sediments, it can be seen that ${\tau}_{ce}$ increases from $0.26N/m^2$ to $0.52N/m^2$ and ${\varepsilon}_M$ decreases exponentially from $14.28mg/cm^2\;hr$ to $6.02mg/cm^2\;hr$, as the bed density varies from $1.17g/cm^3$ to $1.34g/cm^3$. The erosional parameters of Saemankeum sediments are found to be remarkably different in quantity as compared with those for cohesive sediments from other sites. Particularly, ${\tau}_{ce}$ for Saemankeum sediments is known to be larger than that of Kunsan sediments but similar with that of Shihwa sediments, while ${\varepsilon}_M$ for Saemankeum sediments is shown to be smaller than that for Kunsan sediments.

Experimental Study on the Self-extinguishing Performance of Extruded Polystyrene Insulation for Buildings and Suggestions on Institutional Management (건축용 압출법 단열판(XPS)의 자기소화성에 대한 실험적 연구 및 제도적 관리에 관한 제언)

  • Kang, Jung Ki;Choi, Don Mook
    • Fire Science and Engineering
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    • v.34 no.3
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    • pp.141-149
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    • 2020
  • The Korea Industrial Standards (KS) stipulates methods and test procedures for measuring the horizontal combustibility of cellular plastics exposed to small flames (KS M ISO 9772:2018) and recommendations regarding the magnetic digestion of extruded polystyrene insulation (XPS) for measurement results (KS M 3808:2020). Although products that are certified to conform to KS standards must have burning characteristics (self-extinguishing), they are incinerated and spread by welds at construction sites, causing significant human and property damages. In this study, XPS produced by five companies, certified by KS, and sold in the market were purchased and tested for ignition and diffusion caused by a weld bullion at a construction site. The results showed that the five products had differences in performance. Three out of the five products were found to be self-saturated, but the other two were easily ignited and diffused, making it difficult for them to be self-extinguishing. Based on the result of this experimental investigation in line with the KS regulations, all the three types of products, including two types of products that were incinerated through weld defects, were found to be non-self-extinguishing, as specified in KS M 3808.

Assessment for Inhalation Exposure to Trihalomethanes (THMs) and Chroline and Efficiency of Ventilation for an Indoor Swimming Pool (일개 실내수영장의 공기 중 염소 및 트리할로메탄의 노출평가 및 환기 효율 평가)

  • Park, Hae-Dong;Park, Hyun-Hee;Shin, Jung-Ah;Kim, Tae-Ho
    • Journal of Environmental Health Sciences
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    • v.36 no.5
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    • pp.402-410
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    • 2010
  • The objectives of this study were to evaluate the air quality surrounding an indoor swimming pool, to estimate the cancer risk based on the airborne exposure to trihalomethanes (THMs), and to examine the ventilation efficiency by Computational Fluid Dynamics (CFD). Chlorine and THMs were measured poolside, and in the staff room and reception area. The indoor swimming pool was modeled using the Airpak program, with ventilation drawings and actual survey data. Temperature, flow and mean age of the air were analyzed. Levels of chlorine poolside, and in the staff room, and reception area were $203\;{\mu}g/m^3$, $5\;{\mu}g/m^3$, and $10\;{\mu}g/m^3$, respectively. Chloroform was the dominant THM in all sampling sites and mean concentrations were $16.30\;{\mu}g/m^3$, $0.51\;{\mu}g/m^3$, and $0.06\;{\mu}g/m^3$ poolside, in the staff room and reception area, respectively. Bromodichloromethane and Dibromochloromethane levels were respectively estimated as $10.3\;{\mu}g/m^3$ and $1.7\;{\mu}g/m^3$ poolside, $1.3\;{\mu}g/m^3$ and $0.1\;{\mu}g/m^3$ in the staff room, and were not detected in the reception area. The cancer risks from inhalation exposure to THMs were estimated between $3.37{\times}10^{-7}$ and $1.84{\times}10^{-5}$. A short circulation phenomenon was observed from the supply air vents to the exhaust air vents located in the ceiling. A high temperature layer was formed within one meter of the ceiling, and a low temperature layer was formed under this layer due to the low velocity and high temperature of the supply air, and the improper locations of the supply air vents and exhaust air vents. The stagnation was evident at the above adult pool and the mean age of the air was 22 minutes. Disinfection by-products in the indoor swimming pool were present in higher concentrations than in the outdoor air. In order to increase the removal of pollutants, adjustment was required of the supply air volume and the supply/exhaust position.

Shear Strength Characteristics of Artificial Soil Mixture with Pond Ash (매립석탄회가 혼합된 인공혼합토의 전단특성)

  • Kim, Kyoungo;Park, Seongwan
    • Journal of the Korean GEO-environmental Society
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    • v.14 no.10
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    • pp.39-47
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    • 2013
  • Recently, there have been various domestic construction activities related to the reclamation of the dredged soils to expand the land use. However, the reclaimed grounds made of the dredged soils cause various problems due to highly compressible and low shear strength nature. Particularly, this nature induces huge problems in case of the harbor facilities and road construction on the reclaimed sites. Furthermore, in the reclamation activities, the marine dredged soils are often used instead of the well sorted sand, which induces problems of compressibilities. Therefore, in this study, the mechanical characteristics of artificial soil mixture of kaolinite representing the marine dredged soils and the pond ash. A large consolidometer is designed and manufactured to produce the artificial soil mixture. To represent various mixing ratio between the fly ash and bottom ash in the pond ash, six samples with the same stress history are made with different mixing ratio among kaolinite, bottom ash and fly ash. Isotropically consolidated and undrained compression tests are performed to investigate the shear characteristics of soil mixtures. Based on the experimental results, as the components of mixed ash increase, the friction angle increase and the cohesion values decrease. Also, the porepressure parameters at failure, Af increase with the mixing components of the pond ash. The portion of bottom ash has more impact on the shear behavior than that of fly ash.

Soil and Vegetation Characteristics of Abandoned Paddy Field (묵논 습지의 토양 및 식생 특성)

  • Yun, Kwang-Sung
    • Journal of the Korean association of regional geographers
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    • v.13 no.2
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    • pp.129-142
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    • 2007
  • The Purpose of this study is to evaluate the value of abandoned paddy fields as wetland ecosystems and their suitability as habitats for various species. Physical and chemical characteristics of soils and the change of vegetation in paddy fields were analysed -with the passage of time after cease of cultivation. The results of analyses for soil characteristics, vegetation succession, and functional values of abandoned paddy fields as wetlands were as follows: First, top soils become coarser as years after abandonment increase. Second, as the years of abandonment passed. there were significant differences in organic matter, available phosphorate and calcium, while not in magnesium and cation exchange capacity(CEC). Third, species increased from early stage till middle stage, and decreased in late stage. In similarity analysis of species composition, sites were classified into three groups according to the stage of succession. Upper and lower terraces at Daetgol were classified as early stage of succession. The 1st, 2nd and 3rd terraces at Nonbanggol were in middle stage, while tile 4th and 5th were in late stage. Forth, according to evaluation sheets of MoE and RAM(Rapid Assessment Method) standards, me overall average of functional value of Nonbanggol site were 2.13, classified as "common".

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Study on Heavy Metal Contamination Characteristics and Plant Bioavailability for Soils in the Janghang Smelter Area (화학적 추출법에 따른 (구)장항제련소 주변 토양의 중금속 오염특성 분석과 식물 전이 가능량 예측)

  • Jeong, Seul-Ki;An, Jin-Sung;Kim, Young-Jin;Kim, Geon-Ha;Choi, Sang-Il;Nam, Kyoung-Phile
    • Journal of Soil and Groundwater Environment
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    • v.16 no.1
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    • pp.42-50
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    • 2011
  • Potential risk of heavy metals to various receptors including humans depends on the bioavailability of the heavy metals in soil. In this study, the heavy metal extraction methods using 0.1N HCl and aqua regia were compared with the Tessier's sequential extraction method to assess whether these two methods can be used to determine the plant-available heavy metal concentrations. The contamination characteristics of copper (Cu), cadmium (Cd), lead (Pb), and arsenic (As) found in soils collected from 75 sites around the closed Janghang smelter were analyzed by extracting heavy metals using 0.1 N HCl, aqua regia, and the Tessier's sequential extraction method. The portion of metals bioavailable to plants is considered as the sum of the fraction 1 (exchangeable) and the fraction 2 (carbonates binding) of the Tessier's 5-step sequential extraction method, which were determined to be 3.1 ${\pm}$ 3.82, 0.6 ${\pm}$ 0.15, 20.6 ${\pm}$ 18.78, and 7.0 ${\pm}$ 6.48 mg/kg for Cu, Cd, Pb, and As, respectively, in this study. When the extraction using aqua regia and the Tessier's extraction method were compared, the extracted Cu and Pb concentrations did not show significant differences, whereas the extracted Cd and As concentrations showed significant differences. These results indicate that the portion of Cd and As in the fraction 5 of the Tessier's sequential extraction can not be extracted using aqua regia. Using aqua regia, which is the official test method, higher concentrations of Cu, Cd, Pb and As were extracted than the sum of the fraction 1 and 2. The results show that only 9, 40, 39 and 10% of Cu, Cd, Pb and As using aqua regia can be uptaken by plants (i.e., plant-available). Using 0.1N HCl, the portion of Cd equivalent to about 66% the fraction 1 could be extracted, while, with Pb, the portion of the fraction 1 and about 90% of the fraction 2 could be extracted. With As, the portion equivalent to the fraction 1, 2 and 79% of the fraction 3 was extracted, while with Cu, the portion equivalent to the fraction 1, 2, 3 and 20% of the fraction 4 was extracted using 0.1N HCl.

The Abuse Potential of α-Piperidinopropiophenone (PIPP) and α-Piperidinopentiothiophenone (PIVT), Two New Synthetic Cathinones with Piperidine Ring Substituent

  • Botanas, Chrislean Jun;Yoon, Seong Shoon;de la Pena, June Bryan;dela Pena, Irene Joy;Kim, Mikyung;Woo, Taeseon;Seo, Joung-Wook;Jang, Choon-Gon;Park, Kyung-Tae;Lee, Young Hun;Lee, Yong Sup;Kim, Hee Jin;Cheong, Jae Hoon
    • Biomolecules & Therapeutics
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    • v.25 no.2
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    • pp.122-129
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    • 2017
  • A diversity of synthetic cathinones has flooded the recreational drug marketplace worldwide. This variety is often a response to legal control actions for one specific compound (e.g. methcathinone) which has resulted in the emergence of closely related replacement. Based on recent trends, the nitrogen atom is one of the sites in the cathinone molecule being explored by designer type modifications. In this study, we designed and synthesized two new synthetic cathinones, (1) ${\alpha}-piperidinopropiophenone$ (PIPP) and (2) ${\alpha}-piperidinopentiothiophenone$ (PIVT), which have piperidine ring substituent on their nitrogen atom. Thereafter, we evaluated whether these two compounds have an abuse potential through the conditioned place preference (CPP) in mice and self-administration (SA) in rats. We also investigated whether the substances can induce locomotor sensitization in mice following 7 days daily injection and challenge. qRT-PCR analyses were conducted to determine their effects on dopamine-related genes in the striatum. PIPP (10 and 30 mg/kg) induced CPP in mice, but not PIVT. However, both synthetic cathinones were not self-administered by the rats and did not induce locomotor sensitization in mice. qRT-PCR analyses showed that PIPP, but not PIVT, reduced dopamine transporter gene expression in the striatum. These data indicate that PIPP, but not PIVT, has rewarding effects, which may be attributed to its ability to affect dopamine transporter gene expression. Altogether, this study suggests that PIPP may have abuse potential. Careful monitoring of this type of cathinone and related drugs are advocated.

Ecosystem Diagnosis and Evaluations Using Various Stream Ecosystem Models (다양한 하천생태모델을 이용한 생태계 진단 및 평가)

  • Kim, Ja-Hyun;Lee, Eui-Haeng;An, Kwang-Guk
    • Korean Journal of Ecology and Environment
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    • v.40 no.3
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    • pp.370-378
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    • 2007
  • The objective of this research was to diagnose integrative ecological health in Bansuk Stream, one of the tributaries of Gap Stream, using the fish assemblage during July 2006${\sim}$April 2006. For this research, we selected six sampling sites and applied some approaches such as the Index of Biological Integrity (IBI), Qualitative Habitat Evaluation Index (QHEI), and necropsy-based Health Assessment Index (HAI). The stream health condition, based on the IBI values, averaged 24 (n= 18, range: $10{\sim}46$), indicating "poor${\sim}$fair" condition according to the criteria of US EPA (1993). Physical habitat condition, based on the QHEI, averaged 116 (n=6, range: $77{\sim}139$), indicating "fair${\sim}$good" condition. Values of IBI were more correlated with 3 metrics of instream cover ($M_1$, r=0.553, p=0.017, n=18), flow/velocity ($M_3$, r=0.627, p=0.005, n=18), and riffes/bends ($M_7$, r=0.631, p=0.005, n=18) than other metrics. Value of HAI in the control was zero (i.e., excellent condition), while the values in the T1 and T2 treatments were 5 (range: 0${\sim}$30) and 50 (range: 40${\sim}$80), respectively. The maximum values of IBI (46) were coincided with zero of HAI. Thus, these approaches seem to be a good tool for a diagnosis and evaluations of stream ecosystem health.