• Journal of Oriental Neuropsychiatry
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• v.21 no.2
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• pp.75-85
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• 2010

Objectives : This study was designed to evaluate the correlation between patterns of dyspepsia(acute dyspepsia, functional dyspepsia, dyspepsia with the organic disease) and autonomic nerve system dysfunction using HRV analysis. Methods : The patient group consisted of 88 patients diagnosed as a dyspepsia (Acute dyspepsia group-35 patients, Functional dyspepsia group-28 patients, Dyspepsia with the organic disease group-28 patients) who visited in the Oriental Medical Hospital of Dong-eui University from 2005.3.OO to 2008.8.OO. And the control group consisted of 33 patients diagnosed as a normal state of stomach during the same period. We checked HRV of the 4 groups over 5 minutes and compared the HRV index between groups. Results : 1. HF, LF, VLF and TP were significantly lower in the acute dyspepsia, functional dyspepsia and organic dyspepsia patient group than in the control group. 2. HF, LF, VLF and TP were higher in the acute dyspepsia patient group than in the organic dyspepsia patient group, but the differences were not statistically significant. 3. HF, LF, VLF and TP were higher in the acute dyspepsia patient group than in the functional dyspepsia patient group, but the differences were not statistically significant. 4. HF, LF, VLF and TP were lower in the functional dyspepsia patient group than in the organic dyspepsia patient group, but the differences were not statistically significant. Conclusions : Compared to the control group, all of the dyspepsia patient groups showed the tendency that the overall activity of the autonomic nervous system and the activity of sympathetic nerves decreased. Although there was no significant difference in the suppression of the autonomic nervous system, chronic dyspepsia patient group was lower than acute dyspepsia patient group, functional dyspepsia patient group was lower than the organic dyspepsia patient group in HRV.

• The Journal of Pediatrics of Korean Medicine
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• v.23 no.3
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• pp.121-131
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• 2009

Objectives This study is to report a case that has an important meaning as a result of treating functional dyspepsia with oriental treatment. We investigated functional dyspepsia in 6 years child who had to continue abdominal distention for a month after gastroenteritis. The child has recovered from all dyspepsia symptoms after treating with oriental medicine. Methods The patient had dyspepsia symptoms all day, especially repeated abdominal distention. He sometimes had nausea, vomiting, diarrhea, abdominal pain. For those symptoms, we treated him with herbal medicine and acupuncture. The aim of treatment was to improve functional dyspepsia without western treatment. We measured patient's abdomen circumference for change of abdominal distention. Results The symptoms of functional dyspepsia were vanished and the patient maintains his condition with oriental medicine treatment without western treatment. After herb medicine treatment and acupuncture treatment the patient's dyspepsia symptoms (nausea, vomiting, diarrhea, abdominal pain, and abdominal distention) were vanished and maintained his condition for two months after complete the treatment. Conclusions This study showed that oriental medicine can elevate the functional dyspepsia children's quality of life with continuous health care and treatment. For more accurate studies, further studies would be needed with more cases.

• The Journal of Internal Korean Medicine
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• v.29 no.4
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• pp.904-912
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• 2008

Objectives : The objective of this study was to investigate the correlation between swallowing acid symptom and autonomic nerve system in dyspepsia patients. Methods : The test for heart rate variability (HRV) was done to 50 dyspepsia patients at the Department of Internal Medicine, Kang-Nam Kyung-Hee Korean Hospital. 21 among 50 patients had swallowing acid symptom and 29 didn't. We checked HRV and compared HRV index between the two groups. We also divided the patients into functional dyspepsia and organic dyspepsia groups, and then checked HRV respectively. Results were as follows : 1. In dyspepsia patients with swallowing acid, LF/HF ratio was higher than the dyspepsia patients without swallowing acid but the result was not statistically significant. 2. TP, LF, VLF, and LF/HF ratio was higher in the functional dyspepsia group than in the organic dyspepsia group. Average age in the organic dyspepsia group was significantly higher than in the other group. Both results showed statistically significant difference. 3. In the functional dyspepsia group, LF/HF ratio was significantly higher in patients with swallowing acid symptom than those without. However, in eructation and nausea symptoms, HRV index was not statistically significant. Conclusion : This study shows the ratio of sympathetic and parasympathetic nerve system increased in the swallowing acid patient group compared with the non-swallowing acid patient group in functional dyspepsia patients.

• The Journal of Internal Korean Medicine
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• v.29 no.3
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• pp.574-581
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• 2008

Objective : Functional dyspepsia is a common disease impeding subjective quality of life. The present study aimed to analyze syndrome differentiation of functional dyspepsia to help with development of oriental therapeutics. Methods : Sixty-eight subjects diagnosed with functional dyspepsia were analyzed and classified into one of five syndrome differentiations. We compared symptomatic characteristics according to the Nepean Dyspepsia Index (NDI), such as severity, kinds of dyspepsia-related complaints and functional dyspepsia quality of life (QOL) among groups. Results : Patients with disharmony between liver and stomach were most prevalent (52.9%), but no patients with complex of fever and cold. The scores of symptom severity and QOL were not significantly different between groups. Each group had a specified pattern of complaints. Conclusions : Clinical-study based analysis of functional dyspepsia constructed by this study, could be useful in objectively developing Oriental medicines for this disease.

• Herbal Formula Science
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• v.17 no.2
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• pp.203-213
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• 2009

Objectives : The aim of this study was to investigate an effect of Bojungiki-Tang in two cases of the Gastric dysmotility-like Dyspepsia in functional dyspepsia Methods : Subjects were 2 patients with Gastric dysmotility-like Dyspepsia. The patients had suffered from a dyspepsia that were not improved by medical treatments. We gave Bojungiki -Tang to the patients 30 minutes after each meal and tried acupuncture and moxibustion 2 times every day. And we had evaluated the condition of patients using a Ryodoraku test and ordinal scales. Results : After the comparison between an admission and discharge date at Ryodoraku test and ordinal scales, we knowed that conditions of two Gastric dysmotility-like Dyspepsia patients had improved. Conclusions : Bojungiki-Tang is effective on the improvement of conditions in the Gastric dysmotility-like Dyspepsia patients.

• Journal of International Academy of Physical Therapy Research
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• v.6 no.1
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• pp.802-808
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• 2015

The purpose of the present study is to apply Maitland orthopedic manual physical therapy to patients to examine the effects of the therapy on the digestive system through serum gastrin tests that can identify the motility of the digestive system and dyspepsia symptoms and can provide basic data for internal medicinal physical therapy. Maitland orthopedic manual physical therapy was implemented on 20 subjects in total, with 10 in a dyspepsia group and 10 in a control group, for 20 minutes per day, three days per week for three weeks, and the following results were obtained. In the control group, serum gastrin values significantly decreased between before and after treatment(p<.01), and among questionnaire items regarding dyspepsia, those regarding epigastric pain and belching showed significant decreases in these symptoms(p<.05). In the dyspepsia group, serum gastrin values significantly decreased between before and after treatment(p<.01) and all questions regarding dyspepsia showed significant decreases in all symptoms(p<.01). According to the analysis, the dyspepsia group decreased significantly more than the control group in serum gastrin values and all dyspepsia symptoms, except for belching(p<.001). Through the present study, it was identified that Maitland orthopedic manual physical therapy can improve dyspepsia symptoms and is an effective treatment method for internal diseases, such as dyspepsia, by improving gastric motility to become close to the normal state.

• The Journal of Internal Korean Medicine
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• v.29 no.2
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• pp.443-455
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• 2008

Objectives : This study was designed to research whether HRV can yield a suitable diagnosis for activity of autonomic nerve system on functional dyspepsia. Methods : The testing of HRV was carried out at the Oriental Medical Center of Dong-Eui University with the participation of 28 functional dyspepsia patients, 25 dyspepsia caused by organic disease patients and 33 control group people. We checked HRV of the three groups for 5 minutes and compared HRV index(frequency domain analysis: HF, LF, VLF, LF/HF Ratio, TP) between groups. Results were as follows : 1. In the frequency domain analysis, HF, LF, VLF, and TP were significantly lower than the control group in the functional dyspepsia patients and dyspepsia caused by organic disease groups. HF, LF, VLF, LF/HF ratio, and TP were not significantly different between functional dyspepsia group and dyspepsia caused by organic disease group. 2. Age in dyspepsia patient group was significantly higher than in the control group. 3. In the frequency domain analysis, LF, VLF, and TP were significantly lower in the functional dyspepsia group than the control group in age 20-30 years. HF, LF, VLF, LF/HF ratio, and TP were not significantly different between the control group and dyspepsia caused by organic disease group in ages 20-30 years. HF, LF, VLF, LF/HF ratio, and TP were not significantly different between functional dyspepsia group and dyspepsia caused by organic disease group in age 20-30 years. Conclusion : According to this study, autonomic nerve system and parasympathetic nerve system decreased more in the functional dyspepsia patient group compared with the control group.

• Journal of Korean Medicine Rehabilitation
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• v.25 no.4
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• pp.113-121
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• 2015

Objectives Functional dyspepsia is a type of disease characterized by bothersome postprandial fullness, early satiation, epigastric pain and burning without structural gastrointestinal disorders. The aim of this study was to evaluate changes in symptoms, quality of life, HRV (Heart Rate Variability) before and after abdominal manipulation therapy in functional dyspepsia patients. Methods We recruited twenty functional dyspepsia patients from the volunteers who applied for this clinical trial. State of Patients were assessed by NDI-K (Nepean Dyspepsia Index Korean Version), HRV (Heart Rate Variability) before treatment. After 4 times of abdominal manipulation therapy for 2 weeks, state of patients were assessed by the same methods. Results Total symptom score and total quality of life score of NDI-K were significantly improved by the abdominal manipulation therapy. After the treatment, the number of subjects within normal range of LF/HF ratio was significantly increased. Although the median of LF/HF ratio did not significantly changed, interquartile range was reduced. Conclusions Abdominal manipulation therapy possibly can be an effective treatment for functional dyspepsia patients, but further studies are needed to demonstrate the effectiveness of abdominal manipulation therapy for functional dyspepsia patients.

• The Journal of Internal Korean Medicine
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• v.32 no.4
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• pp.584-598
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• 2011

Objectives : Functional dyspepsia is a type of disease characterized by bothersome postprandial fullness, early satiation, epigastric pain and burning without structural gastrointestinal disease. The aim of this study was to analyze the characteristics of functional dyspepsia patients and evaluate changes in symptoms, quality of life, and electrogastrography parameters before and after oriental medical interventions. Methods : We recruited forty-six functional dyspepsia patients who visited gastroenterology clinic in the oriental medicine hospital of Kyung Hee University between November 2009 and February 2011. Patients were assessed for their frequency of dyspepsia (based on short form-Leeds Dyspepsia Questionnaire: SF-LDQ), quality of life (based on functional dyspepsia-related quality of life questionnaire: FD-QoL), gastric motility (based on electrogastrography: EGG) on the first visit. Then, the effect of oriental medical interventions was evaluated using EGG on the second visit. Results : The majority of patients had symptoms of nausea and indigestion. The largest decrease in EGG parameters was found in the indigestion group. The frequency of regurgitation and postprandial EGG power % bradygastria showed a significant correlation. Also, significant correlations were found between some items of FD-QoL and some EGG parameters. Compared to the EGG parameters before oriental medical interventions, some parameters after treatment had positive results, implying the improvement of gastric motility disorder. We also found improvement of EGG parameters in both digestant medicinal group and digestant combined with qi-tonifying medicinal group. Conclusions : The results of this study suggest that clinical application of EGG can be an objective diagnostic tool in functional dyspepsia patients visiting oriental medical hospital.

• Journal of Acupuncture Research
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• v.30 no.5
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• pp.77-86
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• 2013

Objectives : The aim of the study was to investigate the characteristics of Ryodoraku score according to dyspepsia in diagnosed as Soeumin by 'portable Ryodoraku device'. Methods : Using Mann-Whitney U test, we divided 34 'Soeumin' patients into two group(normal and with chronic dyspepsia) and analyzed Ryodoraku score, especially in 'the spleen meridian' and 'the stomach meridian' which is belived to be related with dyspepsia. Soeumin subjects are classified by 'Sasang constitutional program' in portable Ryodoraku device. All of them complete the questionnaire regarding their Digestive conditions. 'short from leeds dyspepsia questionnaire(SF-LDQ)' made by rome III diagnostic is chosed as questionnaire. Results: 1. We found the RS measured from a group of people who has chronic dyspepsia was significantly greater than that from control group. 2. Regarding the effect of 'dyspepsia' in Ryodoraku, the mean score of the F6(stomach meridian) in the chronic dyspepsia group was significantly higher than that in the control group. 3. The mean score of the F6(stomach meridian RS) in the chronic dyspepsia group was not significantly higher than that in the control group. 4. In cases where people has chronic dyspepsia, the difference between RS measured in the right-side of a body and that in the left-side of a body was mostly greater than 40, whereas the case of difference that is less than 2 was rare. Conclusions : Portable Ryodoraku device might be used to classify enforce 'Sasang constitution', and also it might be used to analyze 'Ryodoraku data' based on characteristic clinical symptoms of four constitution diagnosis alone.