• Parasites, Hosts and Diseases
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• v.55 no.5
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• pp.473-480
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• 2017

Plasmodium vivax merozoite surface protein-1 (PvMSP1) gene codes for a major malaria vaccine candidate antigen. However, its polymorphic nature represents an obstacle to the design of a protective vaccine. In this study, we analyzed the genetic polymorphism and natural selection of the C-terminal 42 kDa fragment within PvMSP1 gene ($PvMSP1_{42}$) from 77 P. vivax isolates, collected from imported cases of China-Myanmar border (CMB) areas in Yunnan province and the inland cases from Anhui, Yunnan, and Zhejiang province in China during 2009-2012. Totally, 41 haplotypes were identified and 30 of them were new haplotypes. The differences between the rates of non-synonymous and synonymous mutations suggest that $PvMSP1_{42}$ has evolved under natural selection, and a high selective pressure preferentially acted on regions identified of $PvMSP1_{33}$. Our results also demonstrated that $PvMSP1_{42}$ of P. vivax isolates collected on China-Myanmar border areas display higher genetic polymorphisms than those collected from inland of China. Such results have significant implications for understanding the dynamic of the P. vivax population and may be useful information towards China malaria elimination campaign strategies.

• Journal of Surface Science and Engineering
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• v.34 no.5
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• pp.395-402
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• 2001

An induction thermal plasma system have been newly designed for advanced operation with a pulse modulated mode to control the plasma power in time domain and to create non-equilibrium effects such as fast quenching of the plasma to produce new functional materials in high rate. The system consists of MOSFET power supply with a maximum power of 50 kW with a frequency of 460 kHz, an induction plasma torch with a 10-turns coil of 80 mm diameter and 150 mm length and a vacuum chamber. The pulse modulated plasma was successfully generated at a plasma power of 30 kW and a high pressure of 100 kPa, with taking the on and off time as 10 ms, respectively. Measurements were carried out on the time-dependent spectral lines emitted from Ar species. The dynamic behavior of plasma temperature in a pulse cycle was estimated by the Boltzmann plot and the excitation temperature of Ar atom was found to be changed periodically from around 0.5 to 1.7 eV during the cycle. Two application regions of the induction thermal plasma newly generated were introduced to material processing with high rate synthesis based on non equilibrium effects, and to the finding of new arc quenching gases coming necessary for power circuit breaker, which is friendly with earth circumstance alternative to SF6 gas.

• Journal of the Korean Society for Precision Engineering
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• v.20 no.5
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• pp.204-209
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• 2003

An elastomeric bushing is a device used in automotive suspension systems to reduce the load transmitted from the wheel to the frame of the vehicle. A bushing is an elastomeric hollow cylinder which is bonded to a solid steel shaft at its inner surface and a steel sleeve at its outer surface. The relation between the load applied to the shaft or sleeve and the relative deformation of elastomeric bushing is nonlinear and exhibits features of viscoelasticity. A load-displacement relation for elastomeric bushing is important for dynamic numerical simulations. A boundary value problem for the bushing response leads to the load-displacement relation which requires complex calculations. Therefore, by modifying the constitutive equation fur a nonlinear viscoelastic incompressible material developed by Lianis, the data fur the elastomeric bushing material was obtained and this data was used to derive the new load-displacement relation for radial response of the bushing. After the load relaxation function for the bushing is obtained from the step displacement control test, Pipkin-Rogers model was developed, Solutions were allowed fur comparison between the results of Modified Lianis model and those of the proposed model. It is shown that the proposed Pipkin-Rogers model is in very good agreement with Modified Lianis model.

• Proceedings of the KSME Conference
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• 2003.04a
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• pp.415-419
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• 2003

An elastomeric bushing is a device used in automotive suspension systems to reduce the load transmitted from the wheel to the frame of the vehicle. A bushing is an elastomeric hollow cylinder which is bonded to a solid steel shaft at its inner surface and a steel sleeve at its outer surface. The relation between the load applied to the shaft or sleeve and the relative deformation of elastomeric bushing is nonlinear and exhibits features of viscoelasticity. A load-displacement relation for elastomeric bushing is important for dynamic numerical simulations. A boundary value problem for the bushing response leads to the load-displacement relation which requires complex calculations. Therefore, by modifying the constitutive equation for a nonlinear viscoelastic incompressible material developed by Lianis, the data for the elastomeric bushing material was obtained and this data was used to derive the new load-displacement for radial response of the bushing. After the load relaxation function for the bushing is obtained from the step displacement control test, Pipkin-Rogers model was developed. Solutions were allowed for comparison between the results of Modified Lianis model and those of the proposed model. It is shown that the proposed Pipkin-Rogers model is in very good agreement with Modified Lianis model.

• Journal of the Korean Society for Precision Engineering
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• v.24 no.8 s.197
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• pp.138-143
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• 2007

Microstereolithography technology is similar to the conventional stereolithography process and enables to fabricate a complex 3D microstructure. This is divided into scanning and projection type according to aiming at precision and fabrication speed. The scanning MSL fabricates each layer using position control of laser spot on the resin surface, whereas the projection MSL fabricates one layer with one exposure using a mask. In the projection MSL, DMD used to generate dynamic pattern consists of $1024{\times}768$ micromirrors which have $13.68{\mu}m$ per side. The fabrication range and resolution are determined by the field of view of the DMD and the magnification of the projection lens. If using the projection lens with high power, very fine microstructures can be fabricated. In this paper, the projection MSL system adapted to a large surface for array-type fabrication is presented. This system covers the meso range, which is defined as the intermediate range between micro and macro, with a resolution of a few ${\mu}m$. The fabrication of array-type microstructures has been demonstrated to verify the performance of implemented system.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2002.10a
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• pp.703-708
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• 2002

An elastomeric bushing is a device used in automotive suspension systems to reduce the load transmitted from the wheel to the frame of the vehicle. A bushing is an elastomeric hollow cylinder which is bonded to a solid steel shaft at its inner surface and a steel sleeve at its outer surface. The relation between the load applied to the shaft or sleeve and the relative deformation of Elastomeric bushing is nonlinear and exhibits features of viscoelasticity. A load-displacement relation fur elastomeric bushing is important fur dynamic numerical simulations. A boundary value problem for the bushing response leads to the load-displacement relation which requires complex calculations and is hence unsuitable. Therefore, by modifying the constitutive equation for a nonlinear viscoelastic incompressible material developed by Lianis, the data fur the elastomeric bushing material was obtained and this data was used to derive the new load-displacement relation fur radial response of the bushing. After the load relaxation function for the bushing is obtained from the step displacement control test, Pipkin-Rogers model was developed. Solutions were allowed for comparison between the results of Modified Lianis model and those of the proposed model. It is shown that the proposed Pipkin-Rogers model is in very good agreement with Modified Lianis model.

• Macromolecular Research
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• v.12 no.4
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• pp.342-351
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• 2004

Poly(ethylene glycol) (PEG1K) and sulfonated PEG (PEG1K-SO$_3$) methacrylate (MA) copolymers have been prepared and characterized. The structures of the synthesized copolymers were confirmed by $^1$H and $^{13}$ C NMR spectroscopy and elemental analysis. The bulk characteristics of the copolymers were evaluated by viscosity and thermal analysis. The surface properties of the copolymers were investigated using dynamic contact angle measurements and electron spectroscopy for chemical analysis. The hydrophilicity of the surfaces modified with PEG1KMA or PEG1K-SO$_3$MA increased, possibly as a result of the orientation of the hydrophilic PEG1KMA/PEG1K-SO$_3$MA chains into the water phase. Platelets adhered less to the surfaces of the copolymers than they did to a polyurethane control. In addition, adhesion of platelets to the copolymer surfaces decreased upon increasing the chain density of PEG1KMA and sulfonated PEG1KMA in the copolymers. Both bacterial adhesion and protein adsorption were significantly reduced on the copolymer surfaces and their levels differ depending on the kind of surface or media.

• International Journal of Naval Architecture and Ocean Engineering
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• v.9 no.1
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• pp.100-113
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• 2017

Snap rolling during hard turning and instability during emergency rising are important features of submarine operation. Hydrodynamics modeling using a high incidence flow angle is required to predict these phenomena. In the present study, a quasi-steady dynamics model of a submarine suitable for high-incidence-angle maneuvering applications is developed. To determine the hydrodynamic coefficients of the model, static tests, dynamic tests, and control surface tests were conducted in a towing tank and wind tunnel. The towing tank test is conducted utilizing a Reynolds number of $3.12{\times}10^6$, and the wind tunnel test is performed utilizing a Reynolds number of $5.11{\times}10^6$. In addition, least squares, golden section search, and surface fitting using polynomial models were used to analyze the experimental results. The obtained coefficients are presented in tabular form and can be used for various purposes such as hard turning simulation, emergency rising simulation, and controller design.

• Clinical and Experimental Reproductive Medicine
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• v.43 no.3
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• pp.146-151
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• 2016

Objective: This study was conducted to compare the effects of static culture, dynamic culture, and the combination of dynamic culture with specialized surfaces involving co-culture on human embryonic development. Embryos cultured using conventional static culture (SC) techniques served as a control group. We compared dynamic culture using micro-vibration culture (MVC) and micro-vibration with co-culture (MCoC), in which autologous cumulus cells were used as a specialized surface. Methods: We conducted a chart review of patients who were treated between January 2011 and November 2014 in order to compare embryonic development rates and pregnancy rates among the groups. Zygotes were cultured in micro-droplets, and embryos were subsequently selected for transfer. Some surplus embryos were cryopreserved, and the others were cultured for blastocyst development. A micro-vibrator was set at the frequency of 42 Hz for duration of 5 seconds per 60 minutes to facilitate embryo development. Results: No significant differences among the groups were present in patient's characteristics. However, the clinical pregnancy rates were significantly higher in the MVC group and the MCoC group than in the SC group. No significant differences were found in the blastocyst development rate between the SC group and the MVC group, but the blastocyst development rate in the MCoC group was significantly higher than in the SC and MVC groups. Conclusion: The clinical pregnancy rate was significantly increased by the application of micro-vibration to the embryonic cultures of poor responders. The blastocyst development rate was significantly increased by the application of MCoC to surplus embryos.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2023.11a
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• pp.19-20
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• 2023

The pre-qualification system related to floor impact noise is considered ineffective, and thus, the introduction of a post-verification system is being prepared. This is because the performance, which was notarized in the qualification test due to various reasons, was not uniformly confirmed on building construction fields. Industry practitioners perceive that this is due to the influence of factors such as the flatness, levelness and/or thickness of the floor. However, it is very difficult to confirm such facts in a short period of time on the fields, and since the practical application of technology to measure and evaluate quantitatively and the establishment of a system are insufficient, it cannot be said to be a problem that can be brought to the surface. In fact, even when considering the conventional measurement of the dynamic modulus of elasticity, measurements are performed under controlled variables, such as placing a 200mm×200mm buffer material on a flat test-floor. However, in the fields, it is common to lay down larger productions(for example, 900mm×600mm) on the bare floor where significant variables are not controlled, and to construct finishing layers corresponding to the pre-qualified floor system without separately confirming the realization of the dynamic modulus of elasticity in the field conditions. In this study, spatial information of the bare floor on the field was measured and evaluated through a laser scanner. Technical methods for assessing the smoothness, flatness, and thickness of construction surfaces were reviewed, providing key insights for grading the quality of construction based on these criteria. Through further detailed and thorough investigations, it is expected that results suitable for practical application and systematization will be derived.