• Molecules and Cells
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• v.38 no.2
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• pp.180-186
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• 2015

Escherichia coli AcrAB-TolC is a multidrug efflux pump that expels a wide range of toxic substrates. The dynamic nature of the binding or low affinity between the components has impeded elucidation of how the three components assemble in the functional state. Here, we created fusion proteins composed of AcrB, a transmembrane linker, and two copies of AcrA. The fusion protein exhibited acridine pumping activity, suggesting that the protein reflects the functional structure in vivo. To discern the assembling mode with TolC, the AcrBA fusion protein was incubated with TolC or a chimeric protein containing the TolC aperture tip region. Three-dimensional structures of the complex proteins were determined through transmission electron microscopy. The overall structure exemplifies the adaptor bridging model, wherein the funnel-like AcrA hexamer forms an intermeshing cogwheel interaction with the ${\alpha}$-barrel tip region of TolC, and a direct interaction between AcrB and TolC is not allowed. These observations provide a structural blueprint for understanding multidrug resistance in pathogenic Gram-negative bacteria.

• Journal of the Korean Society for Nondestructive Testing
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• v.20 no.6
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• pp.521-537
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• 2000

Ultrasonic imaging is the most widely used modality among modern imaging device for medical diagnosis and the system performance has been improved dramatically since early 90's due to the rapid advances in DSP performance and VLSI technology that made it possible to employ more sophisticated algorithms. This paper describes "main stream" digital signal processing functions along with the associated implementation considerations in modern medical ultrasound imaging systems. Topics covered include signal processing methods for resolution improvement, ultrasound imaging system architectures, roles and necessity of the applications of DSP and VLSI technology in the development of the medical ultrasound imaging systems, and array signal processing techniques for ultrasound focusing.

• Proceedings of the Korea Water Resources Association Conference
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• 2018.05a
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• pp.148-148
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• 2018

Land subsidence caused by excessive groundwater pumping is a serious hydro-geological hazard. The spatial variability in land use, unbalanced groundwater extraction and aquifer characteristics are the key factors which make the problem more difficult to monitor using conventional methods. This study uses the European Space Agency (ESA) Sentinel satellites to investigate and monitor land subsidence varying with different land covers and groundwater use in the arid Quetta valley, Pakistan. The Persistent Scattering Differential Interferometry of Synthetic Aperture Radar (PS-DInSAR) method was used to develop 28 subsidence interferograms of the study area for the period between 16 Oct 2014 and 06 Oct 2016 using ESA's Sentinel-1 SAR data. The uncertainty of DInSAR result is first minimized by removing the dynamic effect caused by atmospheric factors and then filtered using the radar Amplitude Dispersion Index (ADI) to select only the stable pixels. Finally the subsidence maps were generated by spatially interpolating the land subsidence at the stable pixels, the comparison of DInSAR subsidence with GPS readings showed an R 2 of 0.94 and mean absolute error of $5.7{\pm}4.1mm$. The subsidence maps were also analysed for the effect of aquifer type and 4 land covers which were derived from Sentienl-2 multispectral images. The analysis show that during the two year period, the study area experienced highly non-linear land subsidence ranging from 10 to 280 mm. The subsidence at different land covers was significantly different from each other except between the urban and barren land. The barren land and seasonally cultivated area show minor to moderate subsidence while the orchard and urban area with high groundwater extraction rate showed excessive amount of land subsidence. Moreover, the land subsidence and groundwater drawdown was found to be linearly proportional to each other.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.23 no.5
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• pp.568-573
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• 2019

Modern Radars are evolving into MFRs which can search multiple targets simultaneously and then track them. Additionally they should be able to avoid some external jamming signals. Applying to these MFRs, Antennas should be able to perform DBF including to not only real-time beam steering but also multi-beam forming simultaneously. And they can cancel the beam at the specific direction. In this paper, we describe the implementation of sub-array type antenna hardware which can be applying DBF. Also we propose the modified amplitude aperture distribution for suppressing the side lobe level and explain the sub-array receiver design with amplitude tapering. It consists in making the amplitude weighting in 2 steps. In order to compare two weighting cases, we investigate the G/T performance for the array antenna. At the conclusion, we make a comparative study for the dynamic range of every sub-array receiver and present the hardware implementation that is more advantageous for sub-array alignment and calibration in DBF.

• Journal of the Korean Society of Radiology
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• v.83 no.3
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• pp.724-729
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• 2022

A duodenal web is an incomplete diaphragm of the duodenal lumen that causes a partial or (intermittent) complete obstruction. The size of a duodenal web's aperture determines the degree of obstruction, age at presentation, and radiologic findings. We report a case of duodenal web incidentally diagnosed in a 14-month-old boy who presented to the hospital after ingesting a foreign body. We provide a comprehensive report of multiple studies through abdominal radiograph, upper gastrointestinal study, endoscopy, and surgical findings. We emphasize that the duodenum should be considered as the location of the obstruction when infants exhibit delayed discharge or dynamic positioning of a foreign body in a radiologic examination.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.21 no.6
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• pp.573-582
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• 2010

In this paper, X-band transceiver for high resolution wideband SAR systems is designed and fabricated. Also as a technique for enhancing the performance, error compensation algorithm is presented. The transceiver for SAR system is composed of transmitter, receiver, switch matrix and frequency generator. The receiver especially has 2 channel mono-pulse structure for ground moving target indication. The transceiver is able to provide the deramping signal for high resolution mode and select the receive bandwidth for receiving according to the operation mode. The transceiver had over 300 MHz bandwidth in X-band and 13.3 dBm output power which is appropriate to drive the T/R module. The receiver gain and noise figure was 39 dB and 3.96 dB respectively. The receive dynamic range was 30 dB and amplitude imbalance and phase imbalance of I/Q channel was ${\pm}$0.38 dBm and ${\pm}$3.47 degree respectively. The transceiver meets the required electrical performances through the individual tests. This paper shows the pulse error term depending on SAR performance was analyzed and range IRF was enhanced by applying the compensation technique.

• The Journal of Engineering Geology
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• v.11 no.1
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• pp.1-11
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• 2001

The geological characteristics of Korea are that we can encounter the rock layer only after 10m of excavation, methods to presume the rock pressure distribution of the rock layer is urgently needed. When using the existing empiric science of Terzaghi-Peck, Tschebotarioff to measure the rock pressure of the rock layer, underestimate the real strength because of the cohesion is ignored. Therefore calculating the horizontal sliding force of wedge block, which includes the dips and shear strength of discontinuities and surcharge load etc., think to be to getting a closer rock stress of the real rock pressure acting upon the earth structure in rock mass. This research use Coulomb soil pressure theory assuming that the backfill soil will yield wedge failure when it has cohesion, applying Prakash-Saran(l963), and then it uses equilibrium of force and shear strength $\tau$=c+$\sigma$tan $\Phi$ of the cliscontinuities. Analyzing shear strength and dips of cliscontinuities using calculated theory according to the status of discontinuities aperture, we were able to find out that because the cohesion and friction angle of the rock layer itself is large enough, how the dip directions and dips facing the excavation face is the only factor deciding whether or not the rock stress is applied. The evaluated theory of this research should be strictly estimated, so that the many parameters such as c, $\Phi$value, types and structures of rock class, excessive lateral pressure, dynamic load, earthquake, needed later when calculating shear strength of discontinuities and especially the ground water effect acting on rock layer should be coumpted with many measuring data achieve at the insite to study the application.

• Journal of Cadastre & Land InformatiX
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• v.47 no.2
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• pp.79-90
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• 2017

Urban environment represent one of the most dynamic regions on earth. As in other countries, forests, green areas, agricultural lands are rapidly changing into residential or industrial areas in South Korea. Monitoring such rapid changes in land use requires rapid data acquisition, and satellite imagery can be an effective method to this demand. In general, SAR(Synthetic Aperture Radar) satellites acquire images with an active system, so the brightness of the image is determined by the surface roughness. Therefore, the water areas appears dark due to low reflection intensity, In the residential area where the artificial structures are distributed, the brightness value is higher than other areas due to the strong reflection intensity. If we use these characteristics of SAR images, settlement areas can be extracted efficiently. In this study, extraction of settlement areas was performed using TerraSAR-X of German high-resolution X-band SAR satellite and KOMPSAT-5 of South Korea, and object-oriented image classification method using the image segmentation technique is applied for extraction. In addition, to improve the accuracy of image segmentation, the speckle divergence was first calculated to adjust the reflection intensity of settlement areas. In order to evaluate the accuracy of the two satellite images, settlement areas are classified by applying a pixel-based K-means image classification method. As a result, in the case of TerraSAR-X, the accuracy of the object-oriented image classification technique was 88.5%, that of the pixel-based image classification was 75.9%, and that of KOMPSAT-5 was 87.3% and 74.4%, respectively.