• Animal cells and systems
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• 제10권2호
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• pp.73-77
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• 2006

Caspase-11 has been known as a dual regulator of apoptosis and inflammatory response. An unusual feature of caspase-11 is that its expression is induced by apoptotic or proinflammatory stimuli. Utilizing these unusual features of caspase-11, we have developed a simple and sensitive assay method to screen pro- or anti-apoptotic/inflammatory molecules. To develop this assay method, we generated a reporter construct where GFP expression is regulated by caspase-11 promoter. When several types of cultured cells were transfected with this reporter construct and subsequently treated with various apoptotic or proinflammatory molecules, expression of GFP by the activation of caspase-11 promoter was easily detected by fluorescence microscopy or spectrofluorometry. In addition, a reduction of the GFP fluorescence was detected when an agent reported to suppress caspase-11 induction was applied. These results suggest that our reporter system can be used to screen pro- or anti-apoptotic/inflammatory molecules.

• Physical Therapy Rehabilitation Science
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• 제11권4호
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• pp.446-453
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• 2022

Objective: The popularization of smartphones can lead to abnormal cervical alignment in university students. The aim of this study was to investigate the relationship among smartphone screen time, cervical alignment, and muscle function in university students. Design: Cross-sectional study. Methods: Seventy-five university students participated in the study. They completed the evaluation of cervical alignment and muscle function, such as handgrip strength, proprioception, and muscle quality (tone, stiffness, and relaxation time). All participants recorded their general characteristics and individual smartphone screen time before the evaluation. They were evaluated craniovertebral angle (CVA) using smartphone application (angle meter 360) for measuring cervical alignment. The muscle function was assessed using a digital hand-held dynamometer, dual inclinometer, and MyotonPRO device. Results: Of all participants, twenty-five university students had forward head posture (CVA<49°, 33.33%). Independent t-test revealed that there were significant differences on smartphone screen time, muscle stiffness, and muscle relaxation between the participants with and without forward head posture (p<0.05). There were significant correlations between the smartphone screen time and the CVA, muscle tone, and muscle relaxation (r=-0.493, 0.250, and -0.500, respectively). Conclusions: The results indicate that the university students with forward head posture had high smartphone screen time and muscle stiffness compared to the students without forward head posture, and smartphone screen time might be associated with cervical alignment and muscle quality.

• 한국전자파학회논문지
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• 제29권1호
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• pp.1-9
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• 2018

본 논문에서는 건물 내 무선 통신환경 개선을 위한 필름형 이중 대역 주파수 선택 구조를 제안하였다. 제안한 주파수 선택 구조는 간단한 설계 변수를 통해 2.4 GHz와 5 GHz 이중 대역의 공진 주파수를 제어할 수 있는 소형화된 구조로 얇은 투명 필름 위에 스크린 프린팅 방식을 사용하여 설계 및 제작하였으며, 측정을 통해 성능을 확인하였다. 건물 내에 전파환경 성능 분석이 가능한 소프트웨어를 사용하여 설계한 FSS 구조를 건물에 적용했을 때 실외로부터 유입되는 불요신호에 대한 감쇠 성능을 분석하였다. 또한 분석 결과를 검증하기 위하여 실제 건물 내벽에 제작한 FSS 필름을 적용하여 실내 환경의 신호강도를 측정하였다. 측정결과 제작된 이중 대역 주파수 선택 구조는 실제 건축물에 적용할 경우 2.4 GHz와 5 GHz 대역에서 각각 29.4 dB, 15.94 dB의 감쇠 성능을 가짐을 확인하였다.

• 융합정보논문지
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• 제11권4호
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• pp.161-167
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• 2021

본 연구는 노인운전자의 운전능력을 선별하는 검사로서 이중과제가 활용될 수 있는지 확인하고자 노인운전자의 이중과제 수행과 운전 행동간의 상관관계를 알아보았다. 총 32명의 정상 노인운전자를 대상으로 일반적 정보 및 운전 관련 정보를 조사하고 이중과제 수행정도를 알아보기 위하여 Y-DuCog(Yonsei-Dual task Cognitive screening test)를 평가하였다. 운전행동 수준은 K-DBQ(Korean-Driving Behavior Questionnaire)설문을 사용하였다. 연구결과 페그꽂기 과제와 동물이름 말하기를 활용한 이중과제 수행이 K-DBQ의 위반영역의 점수와 유의미한 상관관계를 보였다. 본 연구로 운전능력 선별검사로서 이중과제의 가능성을 확인할 수 있었다.

• 대한방사선기술학회지:방사선기술과학
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• 제29권4호
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• pp.241-247
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• 2006

최근 유방 영상 검사는 의료영상저장전송시스템(Picture Archiving and Communication System, PACS)의 도입과 특수의료장비에 관한 정도관리 실시로 인해 Computed Radiography(CR)과 Digital Radiography(DR)에 관한 관심도와 이용도가 증가하고 있는 추세이다. 본 연구는 유방영상검사에 이용되고 있는 각 시스템별 검출기의 영상 화질을 정도관리 시 사용되는 ACR 팬텀을 이용하여 비교 분석하였다. 평가 방법은 심리적인 방법으로 ACR 팬텀을 이용한 영상의 수치 값을 SPSS 통계프로그램을 이용하여 유의성과 신뢰도를 분석한 결과는 다음과 같다. 1. Fiber에서는 Screen-Film인 경우 3.9점, CR($50\;{\mu}m$)인 경우 4.2점, CR($100\;{\mu}m$)인 경우 3.2점, DR인 경우 4.2점을 얻어 CR($50\;{\mu}m$), DR, Screen-Film, CR($100\;{\mu}m$)순으로 높은 점수를 받았다(P<0.05). 2. Calcification은 Screen-Film인 경우 2.7점, CR($50\;{\mu}m$)인 경우 2.5점, CR($100\;{\mu}m$)인 경우 2.0점, DR인 경우 2.9점을 얻어 DR, Screen-Film, CR($50\;{\mu}m$), CR($100\;{\mu}m$) 순으로 높은 점수를 받았다(0.025(P<0.05). 3. Mass는 Screen-Film인 경우 3.8점, CR($50\;{\mu}m$)인 경우 3.8점, CR($100\;{\mu}m$)인 경우 3.6점, DR인 경우 4.5점을 얻어 DR, CR($50\;{\mu}m$), Screen-Film, CR($100\;{\mu}m$) 순으로 높은 점수를 받았다(P<0.1). 4. 합계점수 평가는 Screen-Film인 경우 10.4점, CR($50\;{\mu}m$)인 경우 10.6점, CR($100\;{\mu}m$)인 경우 8.7점, DR인 경우 11.3점을 얻어 DR, CR($50\;{\mu}m$), Screen-Film, CR($100\;{\mu}m$) 순으로 높은 점수를 받았다. 이상의 결과는 DR, Screen-Film시스템이 CR($100\;{\mu}m$)에 비해 화질이 우수하다는 것을 알 수 있다. 하지만 DR은 소자에 의한 불안정성, Screen-Film은 artifact에 의한 화질 저하 등 단점을 가지고 있으며, 화질 저하가 문제였던 CR시스템 중 Dual-Side방식의 CR($50\;{\mu}m$)을 사용한 경우에는 Screen-Film 시스템과 차이가 없는 것으로 나타났다. 향후 방사선 영상검사가 디지털화 되는 추세이므로 유방영상검사도 각 시스템의 발전과 보완이 필요할 것으로 사료된다.

• 한국염색가공학회:학술대회논문집
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• 한국염색가공학회 2009년도 학술발표대회
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• pp.207-208
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• 2009

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 1999년도 Japanese Journal of Medical Physics
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• pp.403-406
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• 1999

• 대한통합의학회지
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• 제11권1호
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• pp.21-29
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• 2023

Purpose : Using a smartphone while walking districts attention and increases the risk of losing balance or falling. Ankle instability is caused by decreased muscle strength and decreased neuromuscular ability leading to postural control problems. Dual tasks increases the risk of falls by reducing postural control in adults with ankle instability. This study aimed to investigate the effect of performing a dual task on balance and muscle activity in adults with ankle instability using a smartphone. Methods : Forty-nine individuals with ankle instability participated in this study. A game of finding the wrong picture was performed using a smartphone in the dual task, and only looking at the blank screen of a smartphone was evaluated in the single task. The participants randomly performed single and dual task to evalutate balance and muscle atcitivy. Balance was evaluated using the Biodex balance system (BBS), and muscle activity was evaluated using surface EMG. Muscle activity of the gastrocnemius and tibialis anterior was measured at the same time as balance. Results : The results of this study showed that overall, anteior/posterior, and medial/lateral balance indices all showed significant differences when performing the dual task compared with those during the single task (p<.05). The muscle activity results showed a significant difference compared with that of the gastronemius muscle on the nondominant side during the dual task (p>.05). Conclusion : The results of this study showed that maintaining balance is more difficult when performing the dual task than during the single task, and only the muscle activity of the nondominant gastrocnemius muscle decreased. The dual task causes a decrease in concentration for postural control, which negatively affects postural stability. Individuals with ankle ankle instability should refrain from performing dual tasks, such as using smartphones, to prevent ankle damage.

• 대한의용생체공학회:의공학회지
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• 제8권2호
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• pp.171-176
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• 1987

Wiener filtering method was applied to the dual energy imaging procedure in digital radiography(D.R.). A linear scanning photodiode arrays with 1024 elements(0.6mm H 1.3mm pixel size) were used to obtain chest images in 0.7 sec. For high energy image acquisition, X-ray tube was set at 140KVp, 100mA with a rare-earth phosphor screen. Low energy image was obtained with X-ray tube setting at 70KVp, 150mA. These measured dual energy images are represented in the vector matrix notation as a linear discrete model including the additive random noise. Then, the object images are restored in the minimum mean square error sense using Wiener filtering method in the transformed domain. These restored high and low energy images are used for computation of the basis image decomposition. Then the basis images are linearly combined to produce bone or tissue selective images. Using this process, we could improve the signal to noise ratio characteristics in the material selective images.

• 한국표면공학회지
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• 제54권6호
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• pp.307-314
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• 2021

Diamond-like carbon (DLC) is difficult to achieve sufficient adhesion because of weak bonding between DLC film and the substrate. The purpose of this study is to improve the adhesion between substrate and DLC film. DLC film was deposited on AISI H13 using linear ion source. To improve adhesion, the substrate was treated by dual post plasma nitriding. In order to define the mechanism of the improvement in adhesive strength, the gradient layer between substrate and DLC film was analyzed by Glow Discharge Spectrometer (GDS) and Scanning Electron Microscope (SEM). The microstructure of the DLC film was analyzed using a micro Raman spectrometer. Mechanical properties were measured by nano-indentation, micro vickers hardness tester and tribology tester. The characteristic of adhesion was observed by scratch test. The adhesion of the DLC film was enhanced by active screen plasma nitriding layer.