• Title/Summary/Keyword: Dual command

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Perioperative stress prolong post-surgical pain via miR-339-5p targeting oprm1 in the amygdala

  • Zhu, Yi;Sun, Mei;Liu, Peng;Shao, Weidong;Xiong, Ming;Xu, Bo
    • The Korean Journal of Pain
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    • v.35 no.4
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    • pp.423-432
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    • 2022
  • Background: The decreased expression of mu-opioid receptors (MOR) in the amygdala may be a key molecular in chronic post-surgical pain (CPSP). It is known that miR-339-5p expression in the amygdala of a stressed rat model was increased. Analyzed by RNAhybrid, miR-339-5p could target opioid receptor mu 1 (oprm1) which codes MOR directly. So, the authors hypothesized that miR-339-5p could regulate the expression of MOR via targeting oprm1 and cause the effects to CPSP. Methods: To simulate perioperative short-term stress, a perioperative stress prolongs incision-induced pain hypersensitivity without changing basal pain perception rat model was built. A pmiR-RB-REPORTTM dual luciferase assay was taken to verify whether miR-339-5p could act on oprm1 as a target. The serum glucocorticoid level of rats was test. Differential expressions of MOR, GFAP, and pERK1/2 in each group of the rats' amygdala were tested, and the expressions of miR-339-5p in each group of rats' amygdalas were also measured. Results: Perioperative stress prolonged the recovery time of incision pain. The expression of MOR was down-regulated in the amygdala of rats in stress + incision (S + IN) group significantly compared with other groups (P < 0.050). miR-339-5p was up-regulated in the amygdala of rats in group S + IN significantly compared with other groups (P < 0.050). miR-339-5p acts on oprm1 3'UTR and take MOR mRNA as a target. Conclusions: Perioperative stress could increase the expression of miR-339-5p, and miR-339-5p could cause the expression of MOR to decrease via targeting oprm1. This regulatory pathway maybe an important molecular mechanism of CPSP.

Implementation of Dual-Kernel based Control System and Evaluation of Real-time Control Performance for Intelligent Robots (지능형 로봇을 위한 이중 커널 구조의 제어 시스템 구현 및 실시간 제어 성능 분석)

  • Park, Jeong-Ho;Yi, Soo-Yeong;Choi, Byoung-Wook
    • Journal of Institute of Control, Robotics and Systems
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    • v.14 no.11
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    • pp.1117-1123
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    • 2008
  • This paper implements dual-kernel system using standard Linux and real-time embedded Linux for the real-time control of intelligent robot systems. Such system provides more useful services including standard Linux thread that is easy to implement complicated tasks and real-time tasks for the deterministic response to velocity control. Here, an open source real-time embedded Linux, XENOMAI, is ported on embedded target board. And for interfacing with motor controller we adopted a real-time serial device driver. The real-time task was implemented with a priority to keep the cyclic control command for trajectory control. In order to validate deterministic response of the proposed system, the performance measurement of the delay in performing trajectory control with feedback loop is evaluated with non real-time standard Linux. The proposed software architecture is anticipated to take advantage of features in both standard Linux and real-time operating systems for the intelligent robot systems.

Dual-Radio Tag System for RFID Tag Mesh Networking (RFID 태그간 메쉬 네트워킹을 위한 듀얼 라디오 태그 시스템)

  • Kim, Jin-Hwan;Yoo, Young-Hwan
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.34 no.11B
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    • pp.1272-1282
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    • 2009
  • This paper consists of two parts: the protocol for tag-to-tag mesh network and the implementation of dual-radio RFID system. Recently, RFID has been adopted in ports or warehouse, being attached to containers and palettes for loading/unloading automation. However, the RFID system has encountered one problem - some tags cannot receive any command from reader intermittently due to signal interference by containers or field equipments (e. g. cranes and yard tractors). This area where reader signal cannot reach is called dead-zone. The proposed method for solving the dead-zone problem is as follows. A zone which can be communicated directly between readers and tags communicates in 433MHz frequency band in compliance with ISO/IEC 18000-7 standard. On the other hand, dead-zone communicates in 2.4GHz frequency band by using tag-to-tag mesh network in compliance with IEEE 802.15.4 standard. The proposed method can not only save much cost to install additional readers but also help resolve the dead-zone problem. Furthermore, it can provide the easier, faster, and more economical network infrastructure.

A Voice Controlled Service Robot Using Support Vector Machine

  • Kim, Seong-Rock;Park, Jae-Suk;Park, Ju-Hyun;Lee, Suk-Gyu
    • 제어로봇시스템학회:학술대회논문집
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    • 2004.08a
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    • pp.1413-1415
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    • 2004
  • This paper proposes a SVM(Support Vector Machine) training algorithm to control a service robot with voice command. The service robot with a stereo vision system and dual manipulators of four degrees of freedom implements a User-Dependent Voice Control System. The training of SVM algorithm that is one of the statistical learning theories leads to a QP(quadratic programming) problem. In this paper, we present an efficient SVM speech recognition scheme especially based on less learning data comparing with conventional approaches. SVM discriminator decides rejection or acceptance of user's extracted voice features by the MFCC(Mel Frequency Cepstrum Coefficient). Among several SVM kernels, the exponential RBF function gives the best classification and the accurate user recognition. The numerical simulation and the experiment verified the usefulness of the proposed algorithm.

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A Simulation Study on the Determination of Storage Location in Automated Warehousing Systems (자동창고 시스템의 저장위치 선정에 관한 시뮬레이션 연구)

  • Sohn, Kwon-Ik;Kim, Chang-Deog;Cho, Yong-Hwan
    • Journal of Industrial Technology
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    • v.14
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    • pp.49-61
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    • 1994
  • This study deals with the automated storage/retrieval systems (AS/RS) where the rack is discrete and the random storage assignment rule is adopted. New storage policies named FNSC (first no-cost zone, second closest-open location) and FNSH (first no-cost zone, second a half side closest-open location) are proposed. Simulation results indicate that performance of FNSH is slightly lower than that of the SCL but it does not need much time to perform. The "stay" strategy of S/R machine is examined as a means of increasing the frequency of dual command.

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An Optimal Boundary Shape for Class-Based Storage Assignment Policy in Automated Storage/Retrieval Systems (자동 입출고 시스템에서 계급 할당규칙에 대한 최적 경계모양)

  • Hwang, Hark;Ha, Jae-Won
    • Journal of Korean Institute of Industrial Engineers
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    • v.16 no.1
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    • pp.99-106
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    • 1990
  • With two-class-based storage assignment policy and dual command cycle in Automated Storage/Retrieval Systems(AS/RS), the problem of determining the region dedicated for class-one item is considered. First, the expected travel time of the S/R machine is derived when the boundary of the class-one region is square. Secondly, a heuristic procedure is proposed which determines sequentially the class-one region in a discrete rack. An application of the procedure generates leaf shape region which confirms that the L-shape partition is not necessarily optimal.

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Digital Transponder Technology for the Exploration of Space (우주 탐사를 위한 디지털 트랜스폰더 기술)

  • Won, Young-Jin;Lee, Jin-Ho;Kim, Jin-Hee;Lee, Sang-Ryool
    • Aerospace Engineering and Technology
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    • v.9 no.2
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    • pp.80-89
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    • 2010
  • Transponder is the significant equipment for the telemetry and telecommand operation between the ground station and the satellite. Recently, various transponder technology like Compact Standard Transponder(CST), Small User Transponder(SUT) for data relay satellite, Dual Mode TT&C Transponder(DMT) for large user, and Deep Space Transponder(DST) for deep space mission have been developed according to the communication method and user requirements. Especially, the transponder based on the digital technology comes into the spotlight in the satellite communication field. This paper describes the various analog transponder technology and the state-of-art digital transponder technology grafted onto the existing analog transponder technology.

Design the Guidance and Control for Precision Guidance Munitions using Reference Trajectory (기준궤적을 이용한 탄도수정탄 유도제어기 설계)

  • Sung, Jae min;Han, Eu Jene;Song, Min Sup;Kim, Byoung Soo
    • Journal of the Korea Institute of Military Science and Technology
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    • v.18 no.2
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    • pp.181-188
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    • 2015
  • This paper present, the result of the guidance and control law for a course correction munitions(CCM) with 2sets of canards positioned in the rotating nose section. The nonlinear simulation model of the CCM was developed based on 7DOF equation of motion. The ability of correcting position was verified by open-loop control input with nonlinear model. The guidance and control command was constructed by reference trajectory which can be obtained with no control. Finally, the performance of the guidance and control law was evaluated through Monte-carlo simulation. The CEP(Circular Error Probability) was obtained by considering the errors in muzzle velocity, aerodynamic coefficient, wind, elevation and azimuth angle and density.

Development of a 4kW, High Efficiency, Series-Resonant DAB Converter (4kW급 고효율 직렬 공진형 DAB 컨버터 개발)

  • Sangmin, Lee;Gil-Dong, Kim;Seung-Hwan, Lee
    • The Transactions of the Korean Institute of Power Electronics
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    • v.27 no.6
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    • pp.498-506
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    • 2022
  • This study proposes a design methodology for bidirectional, series-resonant, dual-active bridge (SRDAB) converters. The circuit parameters of the SRDAB converters are designed by considering the output power and efficiency of the converter. The proposed method can be used to design a high-power, high-efficiency SRDAB converter. A voltage controller is employed to manipulate the output voltage of the converter, and the controller gains are selected using the transfer function and frequency response of the controller. Simulation results show that the output power of the designed SRDAB converter is 2 kW per converter module as designed. In addition, the performance of the voltage controller is evaluated using the simulation and experimental results. The output voltage follows the reference voltage within 10 ms under the step change of the reference command. The output voltage also follows the reference voltage under the step load change. The efficiency of the designed SRDAB converter is 95.6%.

Integrated control of an air-breathing hypersonic vehicle considering the safety of propulsion system

  • Chengkun, Lv;Juntao, Chang;Lei, Dai
    • Advances in aircraft and spacecraft science
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    • v.10 no.1
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    • pp.1-18
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    • 2023
  • This paper investigates the integrated control of an air-breathing hypersonic vehicle considering the safety of propulsion system under acceleration. First, the vehicle/engine coupling model that contains a control-oriented vehicle model and a quasi-one-dimensional dual-mode scramjet model is established. Next, the coupling process of the integrated control system is introduced in detail. Based on the coupling model, the integrated control framework is studied and an integrated control system including acceleration command generator, vehicle attitude control loop and engine multivariable control loop is discussed. Then, the effectiveness and superiority of the integrated control system are verified through the comparison of normal case and limiting case of an air-breathing hypersonic scramjet coupling model. Finally, the main results show that under normal acceleration case and limiting acceleration case, the integrated control system can track the altitude and speed of the vehicle extremely well and adjust the angle deflection of elevator to offset the thrust moment to maintain the attitude stability of the vehicle, while assigning the two-stage fuel equivalent ratio to meet the thrust performance and safety margin of the engine. Meanwhile, the high-acceleration requirement of the air-breathing hypersonic vehicle makes the propulsion system operating closer to the extreme dangerous conditions. The above contents demonstrate that considering the propulsion system safety will make integrated control system more real and meaningful.