• Title/Summary/Keyword: Du Pont System

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The PNPLA3 rs738409 Variant but not MBOAT7 rs641738 is a Risk Factor for Nonalcoholic Fatty Liver Disease in Obese U.S. Children of Hispanic Ethnicity

  • Mansoor, Sana;Maheshwari, Anshu;Guglielmo, Matthew Di;Furuya, Katryn;Wang, Makala;Crowgey, Erin;Molle-Rios, Zarela;He, Zhaoping
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.24 no.5
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    • pp.455-469
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    • 2021
  • Purpose: The rs641738 C>T in membrane-bound O-acyltransferase domain-containing protein 7 (MBOAT7) is implicated, along with the rs738409 C>G polymorphism in patatin-like phospholipase domain-containing protein 3 (PNPLA3), in nonalcoholic fatty liver disease (NAFLD). The association of these polymorphisms and NAFLD are investigated in Hispanic children with obesity. Methods: Obese children with and without NAFLD were enrolled at a pediatric tertiary care health system and genotyped for MBOAT7 rs641738 C>T and PNPLA3 rs738409 C>G. NAFLD was characterized by the ultrasonographic presence of hepatic steatosis along with persistently elevated liver enzymes. Genetic variants and demographic and biochemical data were analyzed for the effects on NAFLD. Results: Among 126 enrolled subjects, 84 in the case group had NAFLD and 42 in the control group did not. The two groups had similar demographic distribution. NAFLD was associated with abnormal liver enzymes and elevated triglycerides and cholesterol (p<0.05). Children with NAFLD had higher percentage of PNPLA3 GG genotype at 70.2% versus 31.0% in non-NAFLD, and lower MBOAT7 TT genotype at 4.8% versus 16.7% in non-NAFLD (p<0.05). PNPLA3 rs738409 C>G had an additive effect in NAFLD; however, MBOAT7 rs641738 C>T had no effects alone or synergistically with PNPLA3 polymorphism. NAFLD risk increased 3.7-fold in subjects carrying PNPLA3 GG genotype and decreased in MBOAT7 TT genotype. Conclusion: In Hispanic children with obesity, PNPLA3 rs738409 C>G polymorphism increased the risk for NAFLD. The role of MBOAT7 rs641738 variant in NAFLD is less evident.

Strategic Management for Growth in International Food Retail Market: Case of Carrefour SA

  • Kim, Renee B
    • Journal of Digital Convergence
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    • v.7 no.1
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    • pp.49-56
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    • 2009
  • This paper provides in-depth analysis of internal and external factors that are important to food retailers' international market expansion, presenting Carrefour as a case. Nine sources of risks inherent in international retail market operation are explored and examined which are critical for Carrefour's international expansion. Key financial ratios of Du Pont System are used to assess Carrefour's performance in local market and relative to competitors. Carrefour's competitive advantages are also explored and compared with Wal-Mart, its major competitor in the international expansion.

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Microstructure and Electrical Properties of $RuO_2$ System Thick Film Resistors ($RuO_2$계 후막저항체의 미세구조와 전기적성질)

  • 구본급;김호기
    • Journal of the Korean Ceramic Society
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    • v.27 no.3
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    • pp.337-344
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    • 1990
  • As a function of sintering temperature and time, the electrical properties of ruthenium based thick film resistors were investigated with microstructure. The variatio of resistivity and TCR(temperature coefficient of resistance)trends of sintered speciman at various sintering temperature were different low resistivity paste(Du Pont 1721) from high one(Du Pont 1741). These phenomena are deeply relative to microstructure of sintered film. With increasing the sintering temperature for 1721 system, the electrical sheet resistivity decreased, but again gradually increased above 80$0^{\circ}C$. And TCR trends in 1721 system are all positive. On the other hand the electrical sheet resistivity of 1741 resistor system decreased with sintering temperature. And TCR trends variable according to sintering temperature. TCR of speciman sintered at $700^{\circ}C$ was negative value, and TCR of 80$0^{\circ}C$ sintered speciman coexisted negative and positive value. But in case of speciman sintered at 90$0^{\circ}C$, TCR was positive value. As results of this fact, it was well known that the charge carrier contributied to electrical conduction in 1741 resistor system varied with sintering temperature.

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Simultaneous Determination of Alkaline Earth Metal Ions by a Conventional High Performance Liquid Chromatographic System

  • Rho, Young-Soo;Choi, Seung-Gi
    • Archives of Pharmacal Research
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    • v.9 no.4
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    • pp.211-214
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    • 1986
  • A simultaneous determination method of alkaline earth metals was attempted with the conventional high performance liquid chromatographic system. Four cations, namely, magnesium, calcium, strontium and barium ion, were injected directly as aqueous solution into an eluent containing copper chloride solution and and were successfully separated and determined on a separating column (Zipax SCX, 4.6 mm i.d. ${\times}25$ cm length, Du Pont, USA) by using a variable wavelength UV detector. The linear calibration curves were obtianed in the range from $1.0{\times}10^{-4}M$ to $5.0{\times}10^{-4}M$ and the correlation coefficient of the calibration curve for each metal of magnesium and calcium in tap water. Alkaline earth metals were determined with the conventional high performance liquid chromatographic system.

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Effects of Dipping in Tooth Reserving Solution on Bond Strength of 4-META/MMA-TBB Dentin Bonding System.

  • Kubota, M.;Yanagidani, T.;Hashimoto, M.;Kudou, Y.
    • Proceedings of the KACD Conference
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    • 2001.11a
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    • pp.569.1-569
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    • 2001
  • The purpose of this investigation was to determine the effect of dipping in tooth reserving solution on bond strength of 4-META/MMA-TBB dentin bonding system. The flattened dentin surface of bovine lower incisor was used for this investigation. The tooth were dipped in the tooth reserving solution (ViaSpan; Du Pont Pharmatical / Teeth Server "NEO";Neo Dental Chemical products CO/LTD, Japan/ Saline, Fuso Chemical CO, LTD, Japan) for 30 min.(omitted)

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A Study on the Fluid H in Automotive Air Conditioning System as an Alternative Refrigerant (자동차 공조용 대체 냉매로서의 H냉매에 대한 연구)

  • Choi, Jeong-Won;Nam, Soo-Byeong;Bang, Scott
    • Transactions of the Korean Society of Automotive Engineers
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    • v.15 no.6
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    • pp.170-176
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    • 2007
  • It is time to prepare the phaseout of R134a, the current refrigerant, in automotive air conditioning system because the EC deadline has been coming with new platform vehicles in 2011 and all vehicles by 2017. Until now a high-pressure carbon dioxide($CO_2$) system is the leading replacement of R134a in European auto-makers but there is no firm agreement in the world automotive market. Recently three new fluids have been announced as the possibilities from Honeywell, DuPont and INEOS Fluor. The new alternative refrigerant should meet the requirements like non flammable, non toxic, no ozone depletion effect and low GWP(under 150 to meet EC regulation). The objectives of this paper are to review the fluid H from Honeywell, the more possible alternative refrigerant in 3 new fluids, compare the properties of R134a & fluid H and see the possibility as a replacement of R134a. In this experimental paper we ran and reviewed the cooling performance data in the bench system, the vehicle and the field test. We found the possibility of fluid H system to meet the R134a system performance with some hardware modifications but agreed that it is still needed to study about the long term safety, environmental effects, material compatibilities and so on.

A.C. Impedance Properties on $RuO_2$-Based Thick Film Resistors. ($RuO_2$계 후막저항체의 교류 임피던스특성)

  • Koo, Bon-Keup;Kim, Ho-Gi
    • Proceedings of the KIEE Conference
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    • 1990.07a
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    • pp.215-220
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    • 1990
  • A.C. impedance properties of $RuO_2$ based thick film resistors which having different resistivity value (DuPont 1721 : $100{\Omega}$/ sq., 1741 : $10K{\Omega}$/sq.) were investigated using by impedance analyzer. In case of lower resistivity 1721 system, the complex impedance was composed nearly R component for all speciman sintered at above $600^{\circ}C$, and the frequency dependancy on impedance was not affected very much up to 5MHz and again gradually increase with increasing the frequency. In case of higher resistivity 1741 resistor system, impedance properties were very depandant on sintering temperature. When sintering temperature was $600^{\circ}C$, the complex impedance plot shows a vertical line, which correspond to lone capacitance equivalant circuit, and the impedance linearly decreased with increasing frequency. In case of speciman sintered at $700-900^{\circ}C$, the complex impedance plot shows semi-circular are correspond to a lumped RC combination, and the impedance shows constant value to 5MHz, again decreased with increasing frequency. But the complex impedance behavior of speciman sintered at $1000^{\circ}C$ was shows the equivalent circuit correspont to parallel combined LCR component, and the impedance was not varied with frequency.

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A study on influence of vehicle interior noise according to design parameters of thermoplastic turbo charger intake hose (열가소성 플라스틱 흡기 터보차져호스의 설계 변수에 따른 차량 실내 소음에 미치는 영향에 관한 연구)

  • Jin, Yong-Sun;Youn, Jee-Young;Lee, Choon-Soo
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2012.04a
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    • pp.367-368
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    • 2012
  • In resent years, engineering thermoplastics represent a means for designers to integrate parts, facilitate assembly, reduce weight and lower the costs of their parts to improve the fuel efficiency and competitiveness of the cars. Thermoplastic turbo charger intake hose is one of most sophisticated application in thermoplastics under the hood. Used as part of weight & cost reduction and performance improvement program, thermoplastic turbo charger intake hose has been developed as rubber and metal replacement. For optimized product, NVH performance is a important criteria while keeping same durability required with current system. Though a number of studies have been conducted on the resonator hose and its analytical models, the most of studies were focused on transmission loss itself. This paper presents contribution of vehicle interior noise according to design parameters like profile, bellows type, bellows position, material characteristic. And we will review the design guidance for optimized product of thermoplastic turbo charger intake hose.

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Further Investigations on the Financial Attributes of the Firms listed in the KOSDAQ Stock Market

  • Kim, Hanjoon
    • International Journal of Contents
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    • v.9 no.2
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    • pp.27-37
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    • 2013
  • From the perspective of the domestic capital markets, there have been few researches on the financial characteristics of the firms belonging to the KOSDAQ(Korea Securities Dealers Automated Quotation) market, in comparison with those of the firms in the KOSPI. This study has performed three hypothesis tests to obtain the following results: By employing the 'panel data' analysis, it was found that, for the book-value based leverage, all of the six proposed IDVs were statistically significant as the financial determinants of leverage, across the two proxies measuring profitability (i.e., PFT and ROE), while all of the IDVs except VOLATILITY, also seemed to be the attributes to explain the market based dependent variable in the model with the PFT. Moreover, there may be statistically significant (structural) changes (or quasi-experiment) ) between the pre- and post-U.S. financial crisis in the year of 2008, when measured the leverage with the market-value basis with utilizing the Chow F-test. Finally, based upon the logistic regression results, the probability for a firm to be classified into the Prime section in the KOSDAQ market, may be higher, as its profit margin and asset turnover increase.

Recent Development of Rapid and Automation Technology for Food Microbiological Examination

  • Hiroshi Kurata
    • Proceedings of the Korean Society of Food Hygiene and Safety Conference
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    • 1996.06a
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    • pp.33-33
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    • 1996
  • Interests in the field of rapid methods and automation in microbiology have been growing steadily on an international scale in recent years. International meetings concerned this problem have been held in elsewhere in the world countries since the past twenty years. But, unfortunately in the field of microbial examination in food hygiene, this problem have not yet been developed so much as in the field of clinical microbiology. Today, I would like to introduce you here present aspects of rapid and automation technologies, those which are manly carrying in milk and meats industries. My illustration will be given recent improved technologies using automatic apparatus and instruments along with process of microbial count procedure. Recent direct microbiological counting system (ChemeScan \ulcorner) as real time ultrasensitive analysis created by Cheminex Ltd., France is now most evolutional instrument to provide direct microbial counts, down to one cell, within 30 minutes. The results from these evaluations how a good correlation between the ChemScan system and the standard plate count method. This system will be successful application for not only in the field of pharmacology but also food microbiology. In addition, current identification of microbes by sophisticated instruments suitable for food microbiology, one of which Biology is manual system (BIOLOG\ulcorner), provides reference-level capability at a modes price. For the manual system, the color reactions in the microplate are read by eye and manually keyed into personal computer. Species identification appears on the computer screen within seconds, along with biotype patterns, a list of closely related species, and other useful statistics. In present this is useful application for microbial ecology and epidemiological survey. RiboPrinter system newly produced by DuPont is now focusing among microbiologists in the world, and is one of the biggest microbial characterization system using a DNA-based approach. The technology analyzer is bacterial culture for its genetic fingerprint or riboprint pattern. Finally Bio-cellTracer system for automatic measurement of fungal growth and Fukitori-Maseter, a Surface Hygiene Monitoring Kit by using swabe procedure in food processing environment are briefly illustrated in this presentation.