• 한국컴퓨터정보학회논문지
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• 제25권2호
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• pp.133-140
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• 2020

정보저장 소프트웨어는 DSS(Data Sharing Service), UDP와 같은 통신 방식을 사용하여 전투관리체계에서 송/수신되는 모든 메시지를 분석컴퓨터로 전송하는 기능을 수행한다. 정보저장 소프트웨어는 전투 관리체계에서 사용되는 모든 메시지를 처리하기 때문에 소스코드의 규모가 크며 메시지 변화에 의존성이 강한 특성을 가진다. 소프트웨어의 수정은 연쇄적으로 소프트웨어 신뢰성 시험과 같은 많은 노동력을 요구하는 작업이 발생하기 때문에, 소프트웨어 수정 최소화를 비롯한 소프트웨어 개발 비용 절감을 위한 연구가 지속적으로 이루어지고 있다. 본 논문에서는 전투관리체계 정보저장 소프트웨어의 메시지 변화에 대한 의존성을 최소화하고 수정 용이성의 향상을 위한 메시지 수신 방식 및 아키텍처 구조 개선 방안을 연구하였다. DSS와 UDP 프로토콜을 통하여 메시지를 송/수신하던 기존의 방식을 Packet Sniffing으로 변경함으로써 메시지에 대한 의존성을 줄였으며 팩토리 메소드 패턴(Factory Method Pattern)을 적용하여 소프트웨어 설계를 개선하였다. 기존 소프트웨어와 개발 요소를 비교하는 시험을 통해 소프트웨어의 수정 용이성과 재사용성이 향상 된 것을 확인하였다.

• Clinical and Experimental Reproductive Medicine
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• 제38권2호
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• pp.68-74
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• 2011

Objective: Previously, we found that oocyte specific homeobox (Obox) 4 plays significant role in completion of meiosis specifically at meiosis I-meiosis II (MI-MII) transition. The purpose of this study was to determine the mechanism of action of $Obox4$ in oocyte maturation by evaluating downstream signal networking. Methods: The $Obox4$ dsRNA was prepared by $in$ $vitro$ transcription and microinjected into the cytoplasm of germinal vesicle oocytes followed by $in$ $vitro$ maturation in the presence or absence of 0.2 mM 3-isobutyl-1-metyl-xanthine. Total RNA was extracted from 200 oocytes of each group using a PicoPure RNA isolation kit then amplified two-rounds. The probe hybridization and data analysis were used by Affymetrix Gene-Chip$^{(R)}$ Mouse Genome 430 2.0 array and GenPlex 3.0 (ISTECH, Korea) software, respectively. Results: Total 424 genes were up (n=80) and down (n=344) regulated after $Obox4$ RNA interference (RNAi). Genes mainly related to metabolic pathways and mitogen-activated protein kinase (MAPK) signaling pathway was changed. Among the protein kinase C (PKC) isoforms, PKC-alpha, beta, gamma were down-regulated and especially the MAPK signaling pathway PKC-gamma was dramatically decreased by $Obox4$ RNAi. In the cell cycle pathway, we evaluated the expression of genes involved in regulation of chromosome separation, and found that these genes were down-regulated. It may cause the aberrant chromosome segregation during MI-MII transition. Conclusion: From the results of this study, it is concluded that $Obox4$ is important upstream regulator of the PKC and anaphase-promoting complex action for maintaining intact germinal vesicle.

• Journal of Microbiology
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• 제45권3호
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• pp.187-192
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• 2007

REOviruses (Respiratory Enteric Orphan viruses) are ubiquitous, non-enveloped viruses containing 10 segments of double-stranded RNA (dsRNA) as their genome. They are common isolates of the respiratory and gastrointestinal tract of humans but are not associated with severe disease and are therefore considered relatively benign. An intriguing characteristic of reovirus is its innate oncolytic potential, which is linked to the transformed state of the cell. When immortalized cells are transfected in vitro with activated oncogenes such as Ras, Sos, v-erbB, or c-myc, they became susceptible to reovirus infection and subsequent cellular lysis, indicating that oncogene signaling pathways are exploited by reovirus. This observation has led to the use of the virus in clinical trials as an anti-cancer agent against oncogenic tumors. In addition to the exploitation of oncogene signaling, reovirus may further utilize host immune responses to enhance its antitumor activity in vivo due to its innate interferon induction ability. Reovirus is, however, not entirely benign to immunocompromised animal models. Reovirus causes so-called "black feet syndrome" in immunodeficient mice and can also harm neonatal animals. Because cancer patients often undergo immunosuppression due to heavy chemo/radiation-treatments or advanced tumor progression, this pathogenic response may be a hurdle in virus-based anticancer therapies. However, a genetically attenuated reovirus variant derived from persistent reovirus infection of cells in vitro is able to exert potent anti-tumor activity with significantly reduced viral pathogenesis in immunocompromised animals. Importantly, in this instance the attenuated, reovirus maintains its oncolytic potential while significantly reducing viral pathogenesis in vivo.

• 한국환경과학회지
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• 제2권1호
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• pp.73-81
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• 1993

Adsorption process using granular activated carbon(GAC) has been considered as one of the most effective water treatment technologies to remove humic acid which is recon- niEed as trihalomethane(THM) precursor in chlorination. To design the most effective GAC process, it is necessary to conduct the test of adsor- ption performance by means of isothem, batch rate and column studies and to select the most effective activated carbon according to raw materials of GAC - lignite and coconut shell. The objective of this study is to investigate the adsorption performance of humid acid on two activated carbons - lignite activated carbon(LAC) and coconut shell activated car- bon(CAC) made in Korea. It is available to represent UV-abs and trihalomethane formation potential(THMFP) as concentration of humic acid due to good relationship. The adsorption capacity of humid acid is not concerned with surface area of activated carbon but with pore size related to about $100{\AA}$, and then LAC forming at the extent of mesopore is found to be eight times more effective in adsorption capacity than CAC forming at micropore. The adsorption capacity of LAC and CAC is better at pH 5.5 than at pH 7. Pore and surface diffusion coefficients calculated from the diffusion model are $7.61\times10^{-13}m^2/sec$, $3.52\times10^{-15}m^2/sec$ for CAC, and $3.38\times10^{-12}m^2$/sec and $Ds=1.48{\times}10^{-15}m^2/sec$ for GAC respectively. From the results of column test it shows that the performance of LAC is also better than CAC and the optimal EBCT(Empty Bed Contact Time) is 4.52min. and activated carbon removes selectively the components of humic acid to be easily formed to THM.

• 한국통신학회논문지
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• 제17권9호
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• pp.939-950
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• 1992

Collision-free 전송(傳送) 가능성과 2차 다중(多重) 접속 간섭(干涉)의 영향면에서 다중(多重) 캡쳐 수신기(受信機)를 사용한 단일확산(單一擴散)코드 방식의 성능(性能)이 송신기별(送信機別)(T/O) 코드분할 다중(多重)접속(CDMA) 방식(方式)의 성능(性能)과 비교(比較)된다. 성능비교(性能比較)를 위해, 단일(單一)코드 방식(方式)과 완전한 collision-free 전송(傳送)을 보장하는 T/O CDMA 방식(方式)에 대해 다중(多重)접속 간섭(干涉)의 특징이 서술(敍述)된다. 백색(白色) 가우시안 잡음(雜音)하에서 직접(直接)시퀀스 차동(差動) 위상(位相)편이키잉 데이터 변조(變調)와 forward 에러정정부호화(訂正符號化)를 (BCH 코드) 사용한 위의 두방식(方式)에 대해 throughput 성능(性能)이 평가(評價)된다. 라디오의 수(數)가 비교적 많은 경우에, 적당한 신호대(信號對) 잡음화(SNR)에서 단일(單一)코드 방식(方式)이 T/O CDMA방식보다 최대(最大) throughput을 증가(增加)시킬 수 있음을 확인(確認)하였다.

• 한국통신학회논문지
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• 제25권3B호
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• pp.472-486
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• 2000

This paper analysis the performance of joint receiving structure consisting of the decorrelating multiuser detection and beamfromenr-RAKE receive for DS-CDMA communication systems. In asynchronous transmission as the number of simultaneous users increase. the capacity of CDMA system becomes severly reduced due to the nonideal orthogonality between user-assigned PN sequences and improper power control. Accordingly, the CDMA receiving system becomes vulnerable to the multiple access interferences and the near-far problem under multipath fading channel environment. To withstand these undesired performance degradations, this paper proposes the new type of multiuser detection which has a form of the hybrid structure of concatenating beamformer-RAKE receiver and decorrelating multiuser detection. the beam former-RAKE receiver performs temporal and spatial diversity combining with alleviating fading effect and suppressing undesired interferences, and the multiuser detection plays a role of making the receiver robust to the near-far problem. Regarding the individual merit on the usage of either multiuser detection or beamformer-RAKE receiver, the hybrid one is expected to produce the enhanced performance in multipath fading CDMA channel. However major drawback of using decorrelating multiuser detection for practical deployment is arised from its computational complexity , which is exponentially increased as more number of users and transmitted symbols involve. To diminish the computational complexity, this paper exploits an efficient block Toeplitz inversion technique using matrix Levinson polynomial will be introduced. And this paper provided the mathematical analysis to show the efficiency of the proposed joint structure under the multipath propagation environment. And results of a series of exhaustive computer simulations are presented in order to demonstrate the overall performance of the proposed hybrid structure in multipath fading CDMA channel.

• 한국통신학회논문지
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• 제29권10C호
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• pp.1460-1468
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• 2004

본 논문에서는 실생활에 많이 사용되는 멀티미디어의 연산에 꼭 필요한 명령어를 수행할 수 있는 저면적의 저전력 SIMD MAC/MAS(Single Instruction Multiple Data Multiply and ACcumulate/Multiply And Subtract)를 개발하였다. 개발의 목적이 이전에 개발된 64-bit의 고면적, 고성능 MAC/MAS를 저면적, 저비용화하면서 성능 저하를 최소화 하는 것이었기 때문에 이전에 개발된 구조와 비교함으로써 이번 연구의 성과를 판단하였다. 본 논문의 내용은 크게 SIMD MAC의 설계에 대한 내용, 본 설계가 이전의 설계와의 차별성, 그리고 합성 결과 및 결론으로 이루어져 있다. 설계 결과, 이전에 설계되었던 고성능의 64비트 SIMD MAC/班AS에 비해 전체적인 하드웨어의 크기는 32%로 축소되었다. 이는 임베디드 DS(Digital Signal Processor)에 적합하도록 ISA(Instruction Set Architecture)를 개선하였고, 내부 데이터의 대역폭을 32비트로 줄였으며 하드웨어를 보다 최적화하여 설계하였기 때문으로 판단된다.

• 한국전자파학회논문지
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• 제13권1호
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• pp.33-39
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• 2002

이동통신 시스템에서 지하 주차장, 지하상가, 터널, 빌딩 내부 등과 같이 기지국에 의한 신호의 커버리지가 충분하지 못한 지역들이 발생하게 된다. 이러한 영역의 경제적인 해결 방안으로 중계기가 널리 사용된다. 그러나, 중계기의 수가 증가할수록 역방향 링크의 기지국으로 유입되는 잡음 전력이 중계기의 숫자에 비례하여 증가하기 때문에 채널 용량이 감소하게 된다. 수십, 수백개의 중계기가 하나의 기지국에 연결되는 상황에서 이러한 채널 용량의 감소는 더 이상 무시할 수 없다. 본 논문에서는 커버리지 내에 통화 중인 사용자가 없을 때에 자동적으로 동작하지 않는 스위칭 중계기론 제안하였다. 스위칭 중계기를 사용하면 중계기의 커버리지 내에 통화중인 사용자가 없을 때 불필요한 잡음 레벨을 줄일 수 있다. 스위칭 중계기를 사용한 이동통신 시스템의 역방향 링크 채널 용량을 수학적으로 분석하여 스위칭 중계기를 사용하지 않는 상황과 비교하였다. 그 결과 스위칭 중계기를 사용할 때 충분히 채널용량이 개선되었음을 알 수 있었다.

• 건설안전기술
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• 통권43호
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• pp.98-106
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• 2007

In this paper, a ground disturbance effects, strength and consolidation characteristics of soft clay through using the large block samples($\theta$:300mm, H:400mm) and the piston samples, f hose which had been gathered in west coast and south coast. Especially, we have assessed the coefficient of horizontal consolidation when penetrating the mandrel considering the variance of ratio between diameter and height in drainage sample through the experiment of the oedometer test and Rowecell and also investigated the disturbance area in smear zone by interior model test, the strength originated by disturbance, the variance in characteristics of the consolidation. As the result, the large block sample has been investigated that ihe uniaxial compression test(qu) was shown bigger than the piston sample by about 11-19%. Under the size of anistropy in consolidation, the coefficient ratio of consolidation(ch/cv,) perfomed by standard consolidation test(SC) was shown bigger than that of (Cro/Cv) by the Rowecell test. And the coefficient ratio of consolidation(Cro/Cv) perfomed by piston sample was evaluated bigger than that Of (Cro/Cv) by the large block sample by about 0.9-1.9. The coefficient ratio of consolidation along with the variance in ratio of between diameter and height when penetrating the mandrel was shown big difference according to the characteristics of soil of the specimen. In addition, ds/dw of smear zone at the marine clay in west-south was ranged from 1.6 to 4.2. The width of variance in rat io[(qud)/(quud)] of strength n the area between disturbance and undisturbance was shown big as about 72-91% but the principle was judged with the similiar range when the decrease of the strength in smear zone become the zone under 25% in unditurbance area.

• 한국대기환경학회지
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• 제24권1호
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• pp.43-54
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• 2008

Management and control of ammonia at the sources and ambient largely depend on sampling and measurement techniques. Good sampling and measurement techniques provide high quality data. The main purpose of the study is compare the analytical characteristics of the Indolphenol method which is one of the standard method in Korea with automatic analyzers for continued measuring gaseous ammonia. For comparison with other analytical methods, the verification test was designed to evaluate performance parameters; linearity, absorption efficiency, reproducibility and repeatability test, accuracy, and response time test. $R^2$ of calibration curve using IPM and CLM was very high (value is 1.000), but for EcSM $R^2$ value was estimated to be lower than IPM and CLM (as 0.991). The RSD of the CLM ranged from 0.1 to 2.3% over the nine concentration levels measured, %Ds was 0.1 to 10.7%, and average RA over all the measurements was 3.3%. The RSD of IPM and EcSM was ranged from 1.0 to 8.1, 3.9 to 14.0 respectively, and average RA were 8.71, 4.9% respectively. Rise in response times of EcSM was estimated to be 1 minute. It is found to be more sensitive than response time (which ranged from 2 to 9 minute) of CLM. For ammonia concentration measured using the IPM and the CLM from the same ammonia source, linear regression of IPM versus CLM show a slope of 0.805, an intercept of 637 ppb, and $R^2$ of 0.868.