• 제목/요약/키워드: Drug targeting

검색결과 331건 처리시간 0.025초

Nasal Stability of PEGylated Salmon Calcitonins

  • Youn, Yu-Seok;Na, Dong-Hee;Jung, Ju-Young;Park, Eun-Ji;Lee, Sang-Deuk;Lee, Kang-Choon
    • 대한약학회:학술대회논문집
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    • 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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    • pp.222.1-222.1
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    • 2002

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Enhanced in vitro/in vivo Characteristics of Glucagon-like Peptide-1 by PEGylation

  • Han, H.S.;Youn, Y.S.;Oh, S.H.;Hong, S.T.;Lee, J.E.;Lee, S.O.;Lee, K.C.
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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    • pp.298.2-298.2
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    • 2003

  • The insulinotropic hormone, glucagons-like peptide-1 (GLP-1), which has been proposed as a new potential therapeutics for type-II diabetes, but this is metabolized extremely rapidly by the ubiquitous enzyme, dipeptidyl peptidase IV (DPP IV), forming a metabolite, which acts as an antagonist at the GLP-1 receptor. (omitted)

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