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A Study on the achievements of Baek Kwang-hyeon, a Doctor in Chosun Dynasty (의인(醫人) 백광현(白光玹)의 행적 연구)

  • Pahng, Sung-Hye;Kim, Namil;Kim, Do-Hoon;Cha, Wung-Seok
    • The Journal of Korean Medical History
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    • v.26 no.2
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    • pp.99-110
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    • 2013
  • The purpose of this study is to investigate the life and achievements of a doctor whose name is Baek Kwang-hyeon. He was at first a soldier and later became a doctor. After years of practicing, he was chosen as a acupuncture specialist doctor of Royal Office of Medicine. He was also chosen as a Royal doctor. The method to do this study was to read the book "Jisagongyousa Bukyunghumbang(知事公遺事 附經驗方)", which is writing about his life and medical achievements. Also "Seongjeongwon Ilgi(承政院日記)" was searched to find more about Dr. Baek's life. The results were as follows. More unknown records about his life and works could be found. His medical achievements and originality could also be clarified. Through above books and other records, the annual report of his life could be presented at the end of this stuy.

Design of dual-mode bandpass DR filter in a loaded cavity (유전체 공진기가 삽입된 공동공진기를 이용한 이중모드 대역통과 필터의 설계)

  • Park, Do-Young;Yoon, Soon-Il;Park, Mie-Hwa;Na, Seong-Uk;Lee, Kie-Jin
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2004.07b
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    • pp.578-581
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    • 2004
  • 유전체가 삽입된 공동 공진기는 유전체에 대부분의 전자계가 집속되어 있기 때문에, 도체 손실이 매우 적고 높은 Q값과 온도 안정성이 뛰어나다. 동일한 주파수에서 동작하는 다른 필터에 비해 상대적으로 작기 때문에 소형화에도 적합하다. 본 논문에서는 유전체가 삽입된 공동 공진기의 전자기 분포와 특성을 수치해석과 HFSS(High Frequency Structure Simulator)를 이용하여 분석하였고 이 결과를 토대로 HFSS를 이용한 순차적 방법을 도입하여 4-pole 이중모드 대역통과 필터를 설계, 제작하였다.

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Enhanced Anti-Cancer Effect of Snake Venom Activated NK Cells on Lung Cancer Cells by Inactivation of NF-κB

  • Kollipara, Pushpa Saranya;Won, Do Hee;Hwang, Chul Ju;Jung, Yu Yeon;Yoon, Heui Seoung;Park, Mi Hee;Song, Min Jong;Song, Ho Sueb;Hong, Jin Tae
    • Biomolecules & Therapeutics
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    • v.22 no.2
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    • pp.106-113
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    • 2014
  • In the present study, we investigated anti-cancer effect of snake venom activated NK cells (NK-92MI) in lung cancer cell lines. We used snake venom ($4{\mu}g/ml$) treated NK-92MI cells to co-culture with lung cancer cells. There was a further decrease in cancer cell growth up to 65% and 70% in A549 and NCI-H460 cell lines respectively, whereas 30-40% was decreased in cancer cell growth by snake venom or NK-92MI alone treatment. We further found that the expression of various apoptotic proteins such as that Bax, and cleaved caspase-3 as well as the expression of various death receptor proteins like DR3, DR4 and Fas was also further increased. Moreover, consistent with cancer cell growth inhibition, the DNA binding activity of NF-${\kappa}B$ was also further inhibited after treatment of snake venom activated NK-92MI cells. Thus, the present data showed that activated NK cells could further inhibit lung cancer cell growth.

Determination of Valid Dynamic Stability in Wheel Tracking Test of Asphalt Concretes (아스팔트 콘크리트 반복주행 시험에서의 동적안정도 정립에 관한 연구)

  • Kim, K.W.;Kim, J.E.;Kim, B.C.;Doh, Y.S.
    • International Journal of Highway Engineering
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    • v.6 no.3 s.21
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    • pp.37-46
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    • 2004
  • This study was performed to establish valid methodology for determining dynamic stability(DS) of deformation-cycle curve which is obtained through wheel tracking(WT) test, the most widely used method for forecast of rutting tendency of asphalt mixture. Existing Korean and Japanese methods for DS are unrealistic and do not really reflect characteristics of rut resistance of asphalt concretes especially when the slope of deformation-cycle curve is stabilized at the end. It was proved that the new DS developed in this study reflected rut resistance characteristics better than existing methods. It is especially effective to distinguish the mixtures with high DR(depth of rut) but stable slope at the end of curve from the mixture with lower DR and continuous slope. The field evaluation must be followed to prove whether the mixture which shows a high DS value this method perform well in the filed.

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A study on Quality Control of Mammography Equipment in the Gwang-Ju (일부지역 유방 촬영 장비의 정도관리 실태조사 연구)

  • Shin, Ji-Yun;Lee, Sang-Bock;Jin, Gye-Hwan;Lee, Sam-Yeol;Lee, Jun-Haeng
    • Journal of the Korean Society of Radiology
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    • v.2 no.4
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    • pp.11-25
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    • 2008
  • As breast cancer shows the highest incidence among women's cancers, the use of mammography is also increasing as a screening test. Mammography should produce high-quality images for accurate diagnosis. For this, it is necessary to manage the performance and image quality of mammography. Thus, in order to investigate quality control, the present study conducted a questionnaire survey of 37 hospitals registered as breast cancer medical examination centers in Gwang-Ju, concerning their quality control of mammography. In the results of surveying the characteristics of apparatus use for mammography, many respondents did not know about the equipment that they were using. Of the hospitals, 19 (49%) were using film, 19 (49%) CR, and 1 DR. In the results of asking how to do quality control, only 38% answered that they inspected according to the manual. In addition, all the surveyed hospitals had specialized agencies do quality control for them. As to the reason for using agencies, 65% mentioned limitations in personnel, time, distance, etc, and 44% mentioned the absence of machines and materials. These results suggest that quality control is being performed perfunctorily, as well as passively and indifferently as it relies on specialized agencies. Accordingly, it is necessary to provide regular education for enhancing people's perception of quality control and to perform quality control adequately in the presence of Radiologist.

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Performance Improvement of Map Matching Using Compensation Vectors (보정벡터를 이용한 맵 매칭의 성능 향상)

  • Ahn Do-Rang;Lee Dong-Wook
    • The Transactions of the Korean Institute of Electrical Engineers D
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    • v.54 no.2
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    • pp.97-103
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    • 2005
  • Most car navigation systems(CNS) estimate the vehicle's location using global positioning system(GPS) or dead reckoning(DR) system. However, the estimated location has undesirable errors because of various noise sources such as unpredictable GPS noises. As a result, the measured position is not lying on the road, although the vehicle is known to be restricted on the road network. The purpose of map matching is to locate the vehicle's position on the road network where the vehicle is most likely to be positioned. In this paper, we analyze some general map matching algorithms first. Then, we propose a map matching method using compensation vectors to improve the performance of map matching. The proposed method calculates a compensation vector from the discrepancy between a measured position and an estimated position. The compensation vector and a newly measured position are to be used to determine the next estimation. To show the performance improvement of the map matching using compensation vectors, the real time map matching experiments are performed. The real road experiments demonstrate the effectiveness and applicability of the proposed map matching.

The Study of Total Body Modification (TBM) Technique System (Total Body Modification(TBM) 기법에 관한 고찰)

  • Shin, Byung-Cheul;Woo, Young-Min
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.1 no.1
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    • pp.61-71
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    • 2006
  • Objectives : To introduce Total Body Modification(TBM) technique system developed by Dr. Victor Frank DC, DO, ND through combining chiropractic manipulation with osteopathy, acupuncture meridian system, and naturopathy based on his long-time clinical experiences and insights. Methods : After investigating the art, philosophy and science of TBM thechnique, and applying TBM practice under private clinical situation, we compared It with Chuna Korean manual medicine and oriental medicine system. Results : This system deals with correcting human body's functional physiology to potentiate in a favorable manner. TBM uses a neuromuscular reflex test and body access meridian points to tap into the body's biocomputer and read functional programs. Corrections are usually made by means of special respiratory spinal adjustment, cranial, soft tissue, or specific joint manipulation. Conclusions : We found similarities between TBM and Chuna system in the view of Korean Traditional meridian concept. The special combinations and sequences of various alarm points and associated points have clinical effects on the treatment of chronic spinal subluxation pattern. This suggests TBM has significance In the point of the future evolution of Chuna manual medicine in Korea.

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Parturition and Morphological Development of Larvae and Juvenile in Hippocampus kuda from Korea

  • Lee, Gi-Seok;Lee, Sung-Hun;Lee, Jin;Park, Jea-Min;Han, Kyeong-Ho
    • Development and Reproduction
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    • v.22 no.4
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    • pp.361-367
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    • 2018
  • The newborn, Hippocampus kuda larvae were 6.97-8.81, standard length (SL) mm (mean 7.89 mm) and mouth and anuse were open. Dorsal fin rays 15-18 and pectoral fin-rays were counted 8 and had 10-11+21 myotomes, body's bony plate ring being developed strongly in the central axis of myotomes part. 4 days after bearing, the SL was 7.02-9.47 mm (mean 8.24 mm) and nostrils began to open. 12 days after bearing, larvae attained to 8.91-11.2 SL mm (mean 10.0 mm). From this time, their unique predation habit appeared. 21 days bearing, larvae attained to 12.1-14.8 SL mm (mean 13.4 mm) the and thorn of back was enlarged among the plate formed around ring. 41 days bearing, seahorses attained to 17.1-17.8 SL mm (mean 17.4 mm) and the number of body's bony plate ring of the top of rings trunk was 11 and on the tail of them was 33-36, similar to figure of adult.

A Potential Role of fgf4, fgf24, and fgf17 in Pharyngeal Pouch Formation in Zebrafish

  • Sil Jin;Chong Pyo Choe
    • Development and Reproduction
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    • v.28 no.2
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    • pp.55-65
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    • 2024
  • In vertebrates, Fgf signaling is essential for the development of pharyngeal pouches, which controls facial skeletal development. Genetically, fgf3 and fgf8 are required for pouch formation in mice and zebrafish. However, loss-of-function phenotypes of fgf3 and fgf8 are milder than expected in mice and zebrafish, which suggests that an additional fgf gene(s) would be involved in pouch formation. Here, we analyzed the expression, regulation, and function of three fgfs, fgf4, fgf24, and fgf17, during pouch development in zebrafish. We find that they are expressed in the distinct regions of pharyngeal endoderm in pouch formation, with fgf4 and fgf17 also being expressed in the adjacent mesoderm, in addition to previously reported endodermal fgf3 and mesodermal fgf8 expression. The endodermal expression of fgf4, fgf24, and fgf17 and the mesodermal expression of fgf4 and fgf17 are positively regulated by Tbx1 but not by Fgf3, in pouch formation. Fgf8 is required to express the endodermal expression of fgf4 and fgf24. Interestingly, however, single mutant, all double mutant combinations, and triple mutant for fgf4, fgf24, and fgf17 do not show any defects in pouches and facial skeletons. Considering a high degree of genetic redundancy in the Fgf signaling components in craniofacial development in zebrafish, our result suggests that fgf4, fgf24, and fgf17 have a potential role for pouch formation, with a redundancy with other fgf gene(s).

The Significance of Independence Park in Korean Landscape Architectural History (독립공원의 조경사적 의의)

  • Lee, Yoo-Jick
    • Journal of the Korean Institute of Landscape Architecture
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    • v.36 no.1
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    • pp.103-115
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    • 2008
  • This paper investigates the historical significance of Independence Park in Korean landscape architecture by examining the idea and goal, master plan and scheme, and meaning and limitation of the park The construction was announced in July and began with the Independence Arch in the middle of September, 1896. Dr. Philip Jaisohn (Suh Jai-Pil), Counselor of The Privy Office and president of the Independence newspaper, played an important role in park construction. He formally advised the arrangements and general planning of the park, but he actually played a leading role in the park as much as he designed and superintended the erection of the arch. He had the conception of a productive park for cultivating and experimenting with a variety of trees surrounding the monument. In terms of the history of Korean landscape architecture, Independence Park is important in that it is the first modem city park that was tried independently as part of the modernizing-Seoul project and the only park of which object and scheme were revealed. It also strengthens the roots of Korean modem landscape architecture by pushing Korean history of public parks into the prior time to Japanese colonial period and enriches the contents of Korean modem landscape architecture. Independence Park is the original realization of a public park because it was constructed with participation and donations from the planning stage to the construction and use. In addition, it is the goal and means to inspire the spirit of national independence and patriotism in Korean people and lead them to voluntary awakening, enlightenment, and participation. Independence Park, however, was not constructed according to Dr. Jaisohn's original intent due to the lack of funds and the rudimentary level of landscape construction technology. In addition, the location was too far from downtown and accessibility was very difficult. For these reasons, many do not consider the park as having been constructed. However, this kind of view must be changed. Other parks of the time were not detailed and decorated like typical western parks, but were left as public spaces. In other words, these parks should not be judged by comparing them to western parks. This is the same concept as that of the first parks of modem Korea being called 'park land.' These parks were more natural environments than planned gardens.