• Title/Summary/Keyword: Dose conversion

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Screening and Characterization of a Novel Erythritol-producing Microorganism, Moniliella suaveloens var. nigra (새로운 에리스리톨 생산균주인 Moniliella suaveolens var. nigra의 탐색 및 특성)

  • 박지만;박홍우
    • KSBB Journal
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    • v.13 no.3
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    • pp.331-335
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    • 1998
  • Erythritol is a four-carbon sugar alcohol with a low calorific value and non-cariogenicity. Erythritol is a new functional sweetener which can be used as sugar alternative. Erytheitol dose not cause discomfort such as diarrhoea and flatulence upon ingestion. The purpose of this study is to develope a novel process of erythritol economically in a large scale. To obtain a high erythritol producer, we have screened 3500 colonies from molasses, honey and honey combs. We have selected 40 erythritol-producing microorganisms, one of which yields 140g/L erythritol in 40% glucose medium. We have tested this strain in 5L fermentor to examine the fermentation characteristics. Results of fermentation show that the erythritol production was about 1.4g/L$.$hr in 400g/L glucose media with a 42% conversion. Further improvements require mutation for a higher producer, process optimization to reduce glycerol, and suppression of excessive foaming.

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Application of Dose to Curie Conversion Method using MCNP-4C code for the evaluation of Radionuclide Inventory in a Radioactive Waste Container

  • Sang-hee, Kang;Hwang, Ki-ha;Lee, Sang-chul;Lee, Kun-jai;Kim, Tae-wook;Kim, Kyoung-deok;Herr, Young-hoi;Song, Myung-jae
    • Proceedings of the Korean Radioactive Waste Society Conference
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    • 2004.06a
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    • pp.174-174
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    • 2004
  • It is necessary to perform the radionuclide inventory assessment for the disposal of low and intermediate radioactive waste containers. The $\gamma$ nuclide analyzer can be used for the assessment of containers. However, if the radioactivity in the containers is extremely low or high, radionuclide inventory of the containers can not be evaluated properly. Also, gamma scanning method is time consuming and has economical burden to the utilities.(omitted)

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A Study on the Characteristics of Inverter Type X-Ray Genertator (보급형 인버터식 X선발생장치의 특성에 관한 연구)

  • 박수강
    • Proceedings of the KIPE Conference
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    • 2000.07a
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    • pp.26-29
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    • 2000
  • The conventional types of X-ray generators were bulky in physical size and heavy in weight and the control accuracies of the output voltages were not always satisfacotry. The high frequency switching inverter and converter technology on power conversion and control systems have been greatly closed up introducing power semiconducot devices. To decreasing the volume and the weight of high voltage transformer and to stabilize ripple. In this paper the newly developed x-ray generator in a low cost using duty modulation PWM inverter. This system verify improved performance by stabilize ripple of X-ray tube voltage and compared the reproducibility linearity and dose in single phase three phase and PSU.

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EFFECTS OF H2O2, TURBIDITY AND METALS ON SONOCHEMICAL DECOMPOSITION OF HUMIC SUBSTANCES IN WASTEWATER EFFLUENT

  • Kim, Il-Kyu
    • Journal of Korean Society on Water Environment
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    • v.18 no.3
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    • pp.271-282
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    • 2002
  • The sonochemical process has been applied as a treatment method to investigate its effect on the decomposition of humic substances (HS). The reaction kinetics and mechanisms in the process of sonochemical treatment for humic substances in wastewater have also been discussed. It was observed that the metal ions such Fe(II) and Mn(II) showed catalytic effects, while Al(III), Ca(II), and Mg(II) had inhibitory effects on the decomposition of humic substances in sonochemical reaction with hydrogen peroxide. Experimental results also showed factors such as hydrogen peroxide dose affected the formation of disinfection by-products. Two trihalomethanes, chloroform and dichlorobromomethane were formed as major disinfection by-products during chlorination. The depolymerization and the radical reaction of HS radicals appear to occur simultaneously. The final step of the reaction is the conversion of organic acids to carbon dioxide.

Effect of $H_2O_2$ and Metals on The Sonochemical Decomposition of Humic Substances in Wastewater Effluent

  • Jung, Oh-Jun
    • Environmental Sciences Bulletin of The Korean Environmental Sciences Society
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    • v.10 no.S_3
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    • pp.127-137
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    • 2001
  • The sonochemical Process has been applied as a treatment method and was investigated its effect on the decomposition of humic substances(HS). The reaction kinetics and mechanisms in the Process of sonochemical treatment for humic substances(HS) in wastewater have also been discussed. It was observed that the metal ions such as Fe(II) and Mn(II) showed catalytic effects, while Al(III), Ca(II), and Mg(II) had inhibitory effects on the decomposition of humic substances in sonochemical reaction with hydrogen peroxide. Experimental results also showed factors such as hydrogen peroxide dose affected the formation of disinfection by-products. Two trihalomethanes, chloroform and dichlorobromomethane were formed as major disinfection by-products during chlorination. The mechanism of radical reaction is controlled by an oxidation process. The radicals are so reactive that most of them are consumed by HS radicals and hydroxyl radicals can be acted on organic solutes by hydroxyl addition, hydrogen abstraction, and electron transfer. The depolymerization and the radical reaction of HS radicals appear to occur simultaneously. The final steps of the reaction are the conversion of organic acids to carbon dioxide.

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Effect of Lead Ion on The Hepatic Xanthine Oxidase Activity in Vitro (납이온이 잔틴 옥시다제 활성에 미치는 영향)

  • Huh, Keun;Shin, Uk-Seob;Lee, Sang-Hoon;Ann, Won-Hyo
    • YAKHAK HOEJI
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    • v.39 no.5
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    • pp.521-527
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    • 1995
  • This study was done to determine the effect of lead acetate on the activities of the hepatic cytosofic xanthine oxidase and aldehyde oxidase which were well known as oxygen free radical generating enzyme in vitro. Lead ion accelerated the formation of lipid peroxide and the increment of xanthine oxidase(type O) activity and the type conversion ratio from xanthine dehydrogenase to xanthine oxidase dose-dependently. But xanthine dehydrogenase(type D) activity was decreased. Aldehyde oxidase activity was not changed by lead ion. These data suggested that lead-induced cellular to)dcity may be concerned partially with xanthine oxidase mediated lipid peroxidation.

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Numerical studies on the important fission products for estimating the source term during a severe accident

  • Lee, Yoonhee;Cho, Yong Jin;Lim, Kukhee
    • Nuclear Engineering and Technology
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    • v.54 no.7
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    • pp.2690-2701
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    • 2022
  • In this paper, we select important fission products for the estimation of the source term during a severe accident of a PWR. The selection is based on the numerical results obtained from depletion calculations for the typical PWR fuel via the in-house code named DEGETION (Depletion, Generation, and Transmutation of Isotopes on Nuclear Application), release fractions of the fission products derived from NUREG-1465, and effective dose conversion coefficients from ICRP 119. Then, for the selected fission products, we obtain the adjoint solutions of the Bateman equations for radioactive decay in order to determine the importance of precursors producing the aforementioned fission products via radioactive decay, which would provide insights into the assumption used in MACCS 2 for a level 3 PSA analysis in which up to six precursors are considered in the calculations of radioactive decays for the fission product after release from the reactor.

A Study on the Neutron Dosimetry with LiF Thermoluminescent Dosimeters

  • Yoo, Y.S.;Kim, P.S.;Moon, P.S.
    • Nuclear Engineering and Technology
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    • v.7 no.3
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    • pp.191-198
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    • 1975
  • A study was made on the neutron dosimetry in a mixed gamma-neutron field with LiF thermoluminescent dosimeter. In order to estimate the neutron dose in a mixed field, $^{6}$ LiF and $^{7}$ LiF dosimeters were used for fast and thermal neutron doses. The over-all conversion factors for the effects of dosimeter positions were derived for personnel monitoring and the glow curves of the LiF dosimeters for neutron and gamma-ray doses were also analyzed.

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A Study on Usefulness of Clinical Application of Metal Artifact Reduction Algorithm in Radiotherapy (방사선치료 시 Metal artifact reduction Algorithm의 임상적용 유용성평가)

  • Park, Ja Ram;Kim, Min Su;Kim, Jeong Mi;Chung, Hyeon Suk;Lee, Chung Hwan;Back, Geum Mun
    • The Journal of Korean Society for Radiation Therapy
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    • v.29 no.2
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    • pp.9-17
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    • 2017
  • Purpose: The tissue description and electron density indicated by the Computed Tomography(CT) number (also known as Hounsfield Unit) in radiotherapy are important in ensuring the accuracy of CT-based computerized radiotherapy planning. The internal metal implants, however, not only reduce the accuracy of CT number but also introduce uncertainty into tissue description, leading to development of many clinical algorithms for reducing metal artifacts. The purpose of this study was, therefore, to investigate the accuracy and the clinical applicability by analyzing date from SMART MAR (GE) used in our institution. Methode: and material: For assessment of images, the original images were obtained after forming ROIs with identical volumes by using CIRS ED phantom and inserting rods of six tissues and then non-SMART MAR and SMART MAR images were obtained and compared in terms of CT number and SD value. For determination of the difference in dose by the changes in CT number due to metal artifacts, the original images were obtained by forming PTV at two sites of CIRS ED phantom CT images with Computerized Treatment Planning (CTP system), the identical treatment plans were established for non-SMART MAR and SMART MAR images by obtaining unilateral and bilateral titanium insertion images, and mean doses, Homogeneity Index(HI), and Conformity Index(CI) for both PTVs were compared. The absorbed doses at both sites were measured by calculating the dose conversion constant (cCy/nC) from ylinder acrylic phantom, 0.125cc ionchamber, and electrometer and obtaining non-SMART MAR and SMART MAR images from images resulting from insertions of unilateral and bilateral titanium rods, and compared with point doses from CTP. Result: The results of image assessment showed that the CT number of SMART MAR images compared to those of non-SMART MAR images were more close to those of original images, and the SD decreased more in SMART compared to non-SMART ones. The results of dose determinations showed that the mean doses, HI and CI of non-SMART MAR images compared to those of SMART MAR images were more close to those of original images, however the differences did not reach statistical significance. The results of absorbed dose measurement showed that the difference between actual absorbed dose and point dose on CTP in absorbed dose were 2.69 and 3.63 % in non-SMRT MAR images, however decreased to 0.56 and 0.68 %, respectively in SMART MAR images. Conclusion: The application of SMART MAR in CT images from patients with metal implants improved quality of images, being demonstrated by improvement in accuracy of CT number and decrease in SD, therefore it is considered that this method is useful in dose calculation and forming contour between tumor and normal tissues.

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Amino acid, fatty acid, and carbohydrate metabolomic profiles with ginsenoside-induced insecticidal efficacy against Ostrinia furnacalis (Guenee)

  • Liu, Shuangli;Wang, Xiaohui;Zhang, Rui;Song, Mingjie;Zhang, Nanqi;Li, Wanying;Wang, Yingping;Xu, Yonghua;Zhang, Lianxue
    • Journal of Ginseng Research
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    • v.44 no.4
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    • pp.544-551
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    • 2020
  • Background: Previous studies have shown the insecticidal efficacy of ginsenosides. In the present study, we aimed to investigate the metabolic mechanism related to the inhibitory effect of panaxadiol saponins (PDSs) against the Asian corn borer Ostrinia furnacalis (Guenee). Methods: Third instar larvae of O. furnacalis were fed normal diets with different concentrations of PDSs for 4 days. The consumption index, relative growth rate, approximate digestibility, and conversion of ingested and digested food were recorded. A targeted gas chromatographye-mass spectrometry assay was performed to detect the profiles of amino acids, fatty acids, and carbohydrates in larvae of O. furnacalis. In addition, the activity of detoxification-related enzymes was determined. Results and Conclusions: PDSs decreased the consumption index, relative growth rate, approximate digestibility, and conversion of ingested and digested food in the 3rd instar larvae of O. furnacalis in a dose-dependent manner. PDSs decreased 15 free amino acids, 16 free fatty acids, and 5 carbohydrates and increased the levels of palmitoleic acid, palmitic acid, and 9-octadecenoic acid in the 3rd instar larvae. The activity of detoxification-related enzymes, such as acetylcholinesterase, glutathione S-transferase, cytochrome P450, carboxylesterase, trehalase, acid phosphatase, and alkaline phosphatase, was reduced in a dose-dependent manner in the 3rd instar larvae exposed to PDSs. These data confirmed the inhibitory effect of PDSs against growth, food utilization, and detoxification in the 3rd instar larvae of O. furnacalis and the potential for using PDSs as an efficient tool for insect pest management for O. furnacalis larvae.