• Title/Summary/Keyword: Dong-hae

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Experimental Adaptive Fuzzy Sliding Mode Control of an Inverted Pendulur (도립 진자의 적응 퍼지 슬라이딩 모드 제어기 실험)

  • Kim, Sung-Tae;Park, Hae-Min;Kim, Young-Tae
    • Proceedings of the KIEE Conference
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    • 2002.07d
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    • pp.2143-2145
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    • 2002
  • This paper proposes the control problem of an inverted pendulum system based on adaptive fuzzy sliding mode. The universal approximating capability, learning ability, adaptation capability and disturbance rejection are collected in one control strategy. The proposed scheme does not require an accurate dynamic model and the joint acceleration measurement, yet it guarantees asymptotic trajectory tracking. Experimental results perform with an inverted pendulum to show the effectiveness of the approach.

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The effects of the novel IDPc inhibitor, DA-11004, on NADPH generation, insulin secretion, and glucose level in zucker rats

  • Shin, Chang-Yell;Jeong, Mi-Young;Sohn, Jin-Bup;Lee, In-Ki;Son, Mi-Won;Bae, Cheol-Jun;Byun, Jong-Soo;Kim, Dong-Sung;Kim, Soon-Hae
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.130.3-131
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    • 2003
  • The biological effects of NADPH-dependent isocitrate dehydrogenase (IDPc) inhibitor. DA-11004, was examined in obese zucker rats or streptozotocin-induced diabetic SD rats. Diabetes was induced by injection of streptozotocin (50mg/kg) dissolved in citrate buffer (pH 4.8) into the tail vein and induction of diabetes was confirmed by the measurement of the tail blood glucose level at 48h. DA-11004 (30mg/kg, po) was injected for successive 7days and significantly reduced the plasma glucose in streptozotocin-induced diabetic rats (P<0.05). (omitted)

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The effects of the novel IDPc inhibitor, DA-11004, on NADPH generation, insulin secretion, and glucose level in obese diabetic (ob/ ob) mice

  • Lee, In-Ki;Yell, Shin-Chang;Bup, Sohn-Jin;Young, Jeong-Mi;Son-Miwon;Jun, Bae-Cheol;Soo, Byun-Jong;Kim, Dong-Sung;Kim, Soon-Hae
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.132.2-133
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    • 2003
  • The biological effects of NADPH-dependent isocitrate dehydrogenase (IDPc) inhibitor, DA-11004, was investigated in obese diabetic (ob/ ob) mice. DA-11004, metformin, and oxalomalate were daily injected (ip) for 8 weeks and after completing an 8-week period of experiment, mice were sacrificed at 1 hr after the last drugs treatment to collect their blood, liver, and adipose tissues(epididymal and retroperitoneal fat). (omitted)

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DA 11004, a synthetic IDPc inhibitor, inhibits the high fat high sucrose diet-induced obesity in C57BL/6 mice.

  • Jeong, Mi-Young;Shin, Chang-Yell;Sohn, Jin-Bup;Lee, In-Ki;Son, Mi-Won;Bae, Cheol-Jun;Byun, Jong-Soo;Kim, Dong-Sung;Kim, Soon-Hae
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.129.2-130
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    • 2003
  • Recently. it has been known that NADPH-dependent isocitrate dehydrogenase (IDPc) involves in the obesity through production of NADPH, an important cofactor. DA-11004 is a synthetic potent IDPc inhibitor that $IC_{50}$ for IDPc is 1.49$\mu\textrm{M}$ (0.9$\mu$g/ml). The purpose of this study was to evaluate the effects of DA-11004 on the high fat high sucrose (HF)-induced obesity in C57BL/6 mice. (omitted)

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Concentrations of PM10 and Heavy Metals in Incinerators Around of Dong-hae Area (동해시 소각시설 주변의 입자상물질 및 중금속 농도현황에 관한 연구)

  • Son, Bu Soon;Lee, Jong Dae;Jung, Soon Won;Chung, Tae Woong
    • Journal of Environmental Impact Assessment
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    • v.14 no.5
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    • pp.355-363
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    • 2005
  • We studied the concentrations of $PM_{10}$ and heavy metal in the incinerators around Dong-hae from December 2003 to April 2004. The seasonal mean of $PM_{10}$ concentration was less than the value of environmental standard, the lowest ($36.59mg/m^3$) in spring and the highest ($78.54mg/m^3$) in fall. The measured seasonal heavy metals were Fe $503,44ng/m^3$, Mg $410.85ng/m^3$, Na $134.14ng/m^3$, Zn $24.58ng/m^3$ in spring and Na $315.29ng/m^3$, Mg $48.36ng/m^3$, Fe $44.78ng/m^3$, Zn $23.34ng/m^3$ in summer and Na $88.53ng/m^3$, Fe $33.80ng/m^3$, Zn $20,43ng/m^3$, Pb $6.16ng/m^3$ in fall and Na $4603.72ng/m^3$, Fe $575,26ng/m^3$, Al $411.01ng/m^3$, Cr $203.51ng/m^3$ in winter. The relationship between measured metals concentrations showed that Na and Fe were associated with natural sources such as soil. Pb, Cr and Zn were strongly related to urban anthropogenic sources such as fuel combustion.

The Medical Exchange of "SangHanChangHwaHunJiJip" ("상한창화훈지집(桑韓唱和塤篪集)"의 의학문답(醫學問答) 기록과 조일의학(朝日醫學) 교류)

  • Ham, Jeong-Sik;Cha, Wung-Seok;Ahn, Sang-Woo;Kim, Na-Mil
    • Korean Journal of Oriental Medicine
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    • v.14 no.3
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    • pp.155-171
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    • 2008
  • This study examined from "SangHanChangHwaHunJiJip" how medical exchange between doctors of Joseon and Japan affected medical science of Japan. "SangHanChangHwaHunJiJip" is a record that organized the written conversation between doctors and scholars of the Joseon and Edo period when the delegation so-called Joseon Tongsinsa visited Japan in 1719. Even though "SangHanChangHwaHunJiJip" was written by Japanese, but it was comprised of Joseon's advanced medical ideology, especially "DongEuiBogam" that has occupied an important part of the Joseon medical ideology. As a matter of fact, "SangHanChang HwaHunJiJip" contains general theme and medical subject. But until now, it has been hardly studied by medical historians. Many studies were generally made related to Joseon Tongsinsa, a governmental delegation, focused on literary and cultural exchange between Joseon and Japan by historians. "SangHanChangHwaHunJiJip" is no exception to this trend. We can find that doctors of the Joseon and Edo period entered into colloquium, a form of group discussion, about the clinical theme in "SangHanChangHwaHunJiJip". Concretely, the conversation between doctors of Joseon and Japan was about infant disease, infectious disease, folk remedies, medical herbs, moxa cautery, acupuncture, the study of nature, the study of medical books, etc. For example, when doctors of Japan ask a confirmed disease, doctors of Joseon explained it particularly. They had a great effect on in every cultural aspect of Japan, especially its medical field. Through this study of the medical questions and answers in "SangHanChangHwaHunJiJip", I came to know that the doctors of GiHae envoys gave great influence to the medical knowledge of Japan and the GiHae inherited and developed the medical tradition of SinMyo envoys. Through the examination of this study, I could deduct that "JeongJeongDongEuiBogam" which was published by the government of the Edo period is due to not only the contents of DongEuiBogam's advanced medical thought, but also the doctors of GiHae envoy. Also, "SangHanChangHwaHunJiJip" gives us an idea that doctors of GiHae envoys have medical trend of the OnBoHakFa and a group of Japanese doctors has medical trend of the study of nature. I am confident that the improvement of medical science and natural history of the Edo period is due to influence of medical exchange between Joseon and Japan. "SangHanChangHwaHunJiJip" confirms that medical exchange between two countries affected doctors and scholars of the Edo period.

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Metabolism of Eupatilin in the Rats Using Liquid Chromatography/Electrospray Mass Spectrometry

  • Ji, Hye-Young;Lee, Hye-Won;Lee, Hong-Il;Kim, Hae-Kyoung;Shim, Hyun-Joo;Kim, Soon-Hoe;Kim, Won-Bae;Lee, Hye-Suk
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.214.2-214.2
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    • 2003
  • Eupatilin (5,7-dihydroxy-3",4",6-trimethoxyflavone) is an active ingredient of an ethanol extract of Artemisia asiatica (DA-9601) that is used in the treatment of gastritis. In vitro and in vivo metabolism of eupatilin in the rats has been studied by LC- electrospray mass spectrometry. Rat liver microsomal incubation of eupatilin in the presence of NADPH and UDPGA resulted in the formation of four metabolites (M1-M4). M1, M2, M3 and M4 were tentatively identified as 3"- or- 4"-O-demethyl-eupatilin glucuronide, eupatilin glucuronide, 6-O-demethyleupatilin and 3"-or 4"-O-demethyl- eupatilin glucuronide, eupatilin glucuronide, 6-O-demethyleupatilin and 3"-or 4"-O- demethyl-eupatilin glucuronide, eupatilin glucuronide, 6-O demethyleupatilin and 3"-or 4"-O-demethyl-eupatilin glucuronide, respectively. (omitted)

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Comparison of CYP 3A4 metabolism between DA-8159 and Sildenafil in vitro and in vivo

  • Park, Kyung-Jin;Youn, Hae-Sun;Shim, Hyun-Joo;Kim, Soon-Hoe;Yoo, Moo-Hi;Kim, Won-Bae
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.253.1-253.1
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    • 2002
  • DA-8159 is a new PDEV inhibitor, synthesized by Dong-A Pharm, as an oral agent to treat male erectile dysfunction. DA-8159 and sildenafil are mainly metabolized by cytochrome P450 enzyme CYP 3A4. In this study. we compared the metabolism of DA-8159 with sildenafil in vitro and in vivo. First, we quantified the remaining gatio of original compound, DA-8159 and sidenafil., after we incubated drugs for 30 minutes with human liver microsome cytochrome P 450 3A4. (omitted)

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Portable Real-time Internet Streaming Service System (이동형 실시간 인터넷 스트리밍 서비스 시스템)

  • Park, Jin-A;Ju, Hye-Seon;Park, Ju-Eun;Kim, Hae-In;Choi, In-Seon;Lee, Sang-Un
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • 2017.11a
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    • pp.149-150
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    • 2017
  • 현재, 페이스북, 인스타그램 등 다양한 형태로 실시간 스트리밍 서비스를 제공되고 있다. 이로 인해 특정 소수가 아닌 일반인들도 손쉽게 실시간으로 인터넷 스트리밍이 가능하게 되었다. 과거, 스튜디오가 아닌 중계차가 갈 수 없는 곳에서는 실시간 스트리밍 서비스에 제약이 있었던 반면에 지금은 다양한 이동형 장비의 개발을 통해 공간적 제약이 현저히 줄어들었다. 따라서 본 논문에서는 촬영부터 송출까지 이동형 장비를 이용해 언제 어디에서나 실시간 스트리밍 서비스를 제공할 수 있는 시스템을 제안하였다.

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