• Proceedings of the Korea Society for Simulation Conference
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• 1998.10a
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• pp.17-20
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• 1998

The purpose of this paper is to develop a port simulation program for Inchon Port. The arrival and departure data from Inchon Port are analyzed, several probability density functions for the interval time and service time are estimated, and the berthing rules are constructed based on experts experiences. The port simulation program is written in visual basic considering the interarrival p.d.f., service rate p.d.f., berthing rules, and dual-dock system, and is used to analyze the effects of the changes in ship arrival rate and service rate upon the demurrage. It is expected that we can use the simulation results in order to prepare proper service level and to evaluate the appropriate investment strategy to be planned.

• IE interfaces
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• v.20 no.1
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• pp.21-32
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• 2007

This paper deals with the simulation model for A-Mart logistic center design and operations. In developed simulation model, receiving docks, conveyor sorter, conveyor system, shipping docks, material handling devices and manual sorting stations are considered. Three types of cargo such as transfer center cargo, distribution center cargo and supermarket cargo are considered. The simulation model and process animation are developed using the simulation package ARENA. Among various design and operation alternatives consisting of the number of workers of receiving dock, allocation of receiving docks by cargo types, conveyor sorter velocity, the number of folk-lift, the number of manual sorting operators and overall layout, the best alternatives of each subsystem are selected by simulation analysis. The major performance measures such as sorter throughput, utilization of operators at each station, receiving docks utilization and folk-lift utilization are considered for the alternative evaluation.

• Journal of the Korean Chemical Society
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• v.49 no.5
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• pp.449-460
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• 2005

• Proceedings of the Korean Society of Computer Information Conference
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• 2015.07a
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• pp.89-90
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• 2015

본 논문에서는 폐 스마트폰을 활용하기 위한 원격제어 CCTV 시스템에 대하여 기술한다. 시스템은 폐 스마트폰용 애플리케이션과 폐 스마트폰을 거치할 수 있는 스마트독, 그리고 사용자용 애플리케이션으로 구성된다. 폐 스마트폰용 애플리케이션은 스마트독을 제어할 수 있고 영상을 전송할 수 있다. 스마트독은 온도, 습도, 적외선 센서와 서보모터가 장착되어 있다. 사용자용 애플리케이션은 영상을 확인할 수 있고 스마트독의 센서 데이터를 전송받을 수 있다. 본 논문에서 제안하는 시스템은 늘어나는 폐 스마트폰을 효율적으로 활용할 수 있고 적은 비용으로 실내 CCTV 환경을 구축할 수 있다는 장점이 있다.

• Journal of Integrative Natural Science
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• v.6 no.2
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• pp.100-103
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• 2013

Using computational approaches we can dock small molecules into the structures of Macromolecular targets and then score their potential complementarity to binding sites is widely used in hit identification and lead optimization techniques. This review seeks to provide the application of docking in structure-based drug design (binding mode prediction, Lead Identification and Lead optimization), and also discussed how to manage errors in docking methodology in order to overcome certain limitations of docking and scoring algorithm.

• Industrial Engineering and Management Systems
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• v.11 no.4
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• pp.299-309
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• 2012

This paper introduces some of the developments related to the handling equipment in container terminals and various new conceptual handling systems that have been proposed during the last several decades. The basic ideas behind the previous equipment improvements are analyzed to identify future directions that can be used for devising new handling systems. The handling systems in the container terminals include a quayside handling system, transport system, and yard system. In response to the deployment of mega-sized vessels for container transportation systems, productivity improvement has become one of the most urgent issues in the container terminals. This paper analyzes the previous improvements made for achieving higher productivity in the three subsystems of container handling. Some conceptual handling systems are introduced including the linear motor conveyance system (LMCS), automated storage and retrieval systems (AR/RS), overhead grid rail (GRAIL), SPEEDPORT, SuperDock, the automated container system by ZPMC (ACS-ZPMC), and AUTOCON.

• Proceeding of EDISON Challenge
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• 2013.04a
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• pp.125-137
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• 2013

2012년 G 단백질 연결 수용체(G-Protein Coupled Receptors ; GPCR) 연구가 노벨 화학상을 받았다. 상당히 많은 병과 관련되어 있어 잠재력이 크고, 많은 연구가 진행 중이다. 현재 리간드와 단백질간의 정전기적 포텐셜 연구를 통한 예측 연구가 진행되고 있지만, GPCR과 리간드 간의 연구에서 아직 리간드의 전하를 통한 단백질과 리간드간의 상호작용 예측 연구가 되어 있지 않다. 그렇기 때문에 이번 연구에서는 8가지 방법으로 전하(charge)를 띠게 하여서 단백질과 리간드의 상호작용을 계산을 통하여 예측하여 보았다.

• Proceeding of EDISON Challenge
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• 2013.04a
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• pp.13-24
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• 2013

Dopamine agonists and antagonists and its receptor play a critical role in the information transfer in the nervous system, and dopamine receptor-ligands interactions are deeply related to Parkinson's disease, schizophrenia and some other mental diseases. However, the only experimental 3D structure available for dopamine receptors is human D3 dopamine receptor. Therefore, it is important to create model of subtype dopamine receptor-ligands interactions. We report here the 3D structures of the human D1 and D2 dopamine receptor predicted by using GalaxyTBM, and its predicted binding site determined by using GalaxyDock. The highly conserved Asp on TM 3 and Phe on TM 6 have critical role in ligand binding. Also, highly conserved serines on TM 5 are essential for binding agonists and some kinds of antagonists. We identify differences between binding sites of agonists and antagonists of human D1 and D2 dopamine receptor, and find the reasons of selective binding of antagonists.

• Proceeding of EDISON Challenge
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• 2016.03a
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• pp.86-89
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• 2016

The Zika virus, which is a member of the flavivirus genus, poses a serious threat to humanity because there is no vaccine or cure. Zika is suspected to cause microcephaly, and it is rapidly spreading throughout parts of Brazil. Surprisingly, there are no known protein structures for the virus which are essential for drug and vaccine development. This paper investigates the Zika virus's nonstructural proteins with template-based modeling by using GalaxyTBM/Refine/SC. GalaxyDock was used to examine the effectiveness of various known serine protease inhibitors in inhibiting the Zika viral protease. In testing five inhibitors, Kunitz soybean trypsin inhibitor showed the strongest binding affinity (-10.082 kcal/mol). This paper provides a rudimentary foundation for further drug discovery research regarding the Zika virus.

• Journal of Korean Society of Water and Wastewater
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• v.12 no.4
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• pp.53-58
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• 1998

Dissolved Air flotation (DAF) has become increasingly important in the field of drinking water treatment, however, the research to investigate the mechanism of collision between bubble and particle has been limited. The electrostatic repulsion forces between them are critical to collide with each other. Zetapotential of bubble and particle show their electrostatic condition. In this research, a setup to measure the zetapotential of rising microbubble is made using electrophoresis method and measured ZP of bubble in our Lab. The results show the effect of pH on zetapotential of bubble. The findings from this research are compared with other results. It will he helpful to understand and explain the mechanism of collisions between bubble and particle on different conditions of bubble charge in DAF process.