• Title/Summary/Keyword: Do-Hwa-Dong

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Clinical Characteristics of Pulmonary Tuberculosis Presenting Prolonged Fever Despite Primary Short-Course Anti-tuberculosis Treatment (1차 항결핵약제 치료 후에도 지속적으로 발열을 보인 폐결핵 환자의 임상상)

  • Kim, Eun-Kyung;Hwang, Jung-Hwa;Song, Kun-Sick;Lim, Chae-Man;Lee, Sang-Do;Koh, Youn-Suck;Kim, Woo-Sung;Kim, Dong-Soon;Kim, Won-Dong;Shim, Tae-Sun
    • Tuberculosis and Respiratory Diseases
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    • v.49 no.2
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    • pp.169-178
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    • 2000
  • Background : Usually fever subsides within one week in over 90% of pulmonary tuberculosis (TBp) patients after the start of short-course anti-tuberculosis therapy, but occasionally it persists over two weeks after treatment. When the fever persists, drug resistance, combined infection, or drug fever, and so on, are considered as an etiology and, in some cases, drugs are changed. But inadvertent discontinuation of a short-course regimen inevitably will extend the duration of treatment, and the treatment completion may be delayed. This study was performed to investigate the causes of prolonged fever (PF) and to identify the predictors of PF in drug-susceptible TBp patients in Korea. Method : Five hundred-ninety-eight patients, who were admitted to Asan Medical Center from January 1996 to March 1999, diagnosed with TBp and prescribed short-course, anti-tuberculosis treatment, were reviewed. PF was defined as having fever over two weeks despite treatment. The causes of PF were analyzed. Drug-sus-ceptible TBp patients who presented no causes for PF, except turberculosis itself, were selected(n=22), and they were compared with those who had no fever at diagnosis (n=22) and those who had fever at diagnosis, which had subsided within two weeks after treatment (n=22). Clinical, laboratory, and radiological parameters were compared among the three groups. Results : Twenty-eight (4.8%) of 598 patients showed PF over two weeks despite short-course treatment. The causes of PF were drug fever (n=2), multi-drug resistant tuberculosis (n=3), disseminated Mycobacterium kansasii infection (n=1), and drug-susceptible tuberculosis itself (n=22). The patients with PF had more risk factors for tuberculosis, long duration of symptoms before treatment, night sweats, weight long, numerous acid fast bacilli on sputum smear, anemia, hyponatremia, hypoalbuminemia, over three lung cavity numbers and extensive infiltration, indicating that they had prolonged and extensive lung diseases. Conclusion : The main cause of PF in TBp despite short-course regimen seems to be drug-susceptible but extensive disease in Korea. Any changes to the drug regiment provided for TBp patients with prolonged fever despite treatment should be carefully considered.

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Microbial Contamination Levels of Fresh Vegetables Distributed in Markets (유통 중인 신선 채소류의 미생물 오염도 평가)

  • Choi Jin-Won;Park Shin Young;Yeon Ji-Hye;Lee Min Jeong;Chung Duck Hwa;Lee Kyu-Ho;Kim Min-Gon;Lee Dong-Ha;Kim Keun-Sung;Ha Sang-Do
    • Journal of Food Hygiene and Safety
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    • v.20 no.1
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    • pp.43-47
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    • 2005
  • This study monitored and compared the contamination levels of total aerobic bacteria, coliforms, Escherichia coli, and L. monocytogenes of either lettuce, sesame leaf, or cucumber sampled from either 15 super markets(SM) or 21 traditional markets(TM) located in both Seoul and the southern part of Gyunggi. Contamination levels of total aerobic bacteria and coliforms in lettuce, sesame leaf, or cucumber from SM or TM were not (p>0.05) significantly different. The highest contamination levels of total aerobic bacteria were observed in lettuce and followed by sesame leaf and cucumber. The contamination levels of total aerobic bacteria in lettuce, sesame leafs, and cucumbers were $7.01{\pm}0.14\;log_{10}CFU/g(SM)$ and $7.10{\pm}0.11\;log_{10}CFU/g(TM)$, $6.69{\pm}0.20\;log_{10}CFU/g(SM)$ and $6.44{\pm}0.13\;log_{10}CFU/g(TM)$, and $5.37{\pm}0.25 \;log_{10}CFU/g(SM)$ and $5.27{\pm}0.19\;log_{10}CFU/g(TM)$, respectively. A similar pattern of contamination rank was observed with the coliforms in three vegetables as was observed with the total aerobic bacteria E. coli were not significantly (p>0.05) different between SM and TM and isolated over $30\%$ in lettuce and sesame leaf and below $10\%$ in cucumbers. L. monocytogenes were not detected in all three vegetables(ND: cucumber <3 CFU/g, lettuce and sesame leaf <10 CFU/g). The microbial contamination levels determined in the present study may be used as the primary data to execute microbial risk assessment of fresh vegetables.

Comparison of Standard and Lend Limit Test of Various Institutes on Lead Limit of Synthetic and Natural Food Additives (합성 및 천연 식품첨가물의 납함량에 대한 여러 기관의 규격기준 및 납시험법 비교)

  • Shin Dong-Hwa;Kim Yong-Suk;Jeong Do-Yeong;Lee Young-Hwan;Bang Jeong-Ho;Om Ae-Son;Shin Jae-Wook;Lee Tal-Soo;Jang Young-Mi;Hong Ki-Hyoung;Park Sung-Kwan;Park Sung-Kug;Kwon Yong-Kwan
    • Journal of Food Hygiene and Safety
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    • v.21 no.2
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    • pp.82-91
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    • 2006
  • Standard and lead limit test in general test method of Korea, Japan, Joint FAO/WHO Expert Committee of Food Additives (JECFA), USA, and EU on synthetic and natural food additives were compared. There were found that the general test methods in 'Korea Food Additives Code' were different from standards of various institutes on lead limit test. For the lead limit test of food additives, Korea used dithizone method, Japan used atomic absorption spectrophotometry, and USA used dithizone method, flame atomic absorption spectrophotometric method, atomic absorption spectrophotometric graphite furnace method, and APDC extraction method. In addition, JECFA and EU used dithizone method and atomic absorption spectrophotometric method. The dithizone methods of Korea, USA, and JECFA were nearly identical. In the case of USA, JECFA, and EU, the analytical methods for lead limit test were shown in individual monograph. Lead limit test against 13 synthetic, such as magnesium stearate and L-cystine, and 12 natural, such as gua gum and diatomaceous earth, food additives distributed in Korea were performed by the analytical method of each institute. Although all institutes use various methods for analysis of lead, contents of lead in food additives tested fell into the standard of each institute.

Compositions and Contents of Thinner and Reliability of MSDS sold in Busan and Gyeongnam Province (부산,경남에서 판매되는 시너(Thinner)의 구성 성분 중 벤젠 등 일부 독성물질의 함량과 물질안전보건자료에 관한 연구)

  • Kim, Yu Young;Yang, Seung Hyuk;Lee, Jung Sil;Lee, Hyoung Sook;Jang, Kong Hwa;Jin, Koo Won;Lee, Yong Il;Joo, Woo Hong;Paik, Do-Hyeon;Kang, Dae-Ook;Moon, Ja-Young;Cho, Yong-Kweon;Park, Dong Uk;Yoon, Chung Sik;Ha, Kwon Chul
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.16 no.4
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    • pp.314-323
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    • 2006
  • This study was conducted to identify ingredients of thinners and to confirm reliability of material safety data sheets (MSDS) of thinners for public and workers' health. The 41 thinner products were collected from paint shops located in Busan and Gyeongnam province. The 12 thinner products among them were identified using product MSDS. GC-MSD was used to analyze 41 kinds of thinners qualitatively and quantitatively. The 12 products MSDS were compared with thinner's component through qualitative analysis to confirm MSDS. Chemical ingredients, such as Benzene, Toluene, and Xylene etc., of thinners were analysed in quantity. The 41 thinner products contained 17 disclosed specific, trade name, or generically described chemical solvent ingredients. These 17 ingredients came under 6 classes: alcohols, aromatic hydrocarbons, esters, glycol ethers, ketones, and mixtures. These 17 ingredients were important in the view of industrial hygiene and had occupational exposure limit in the ambient, such as toluene, xylene, acetone, nonane, EGEE, heptane, cumene, MIBK, indene, tri-methyl benzene, etc, were found in 41 kinds of thinners. Aromatic hydrocarbons were the most identified ingredient in thinners. Especially, the benzene, which induces leukemia, was found in 4 kinds of thinners. The content rates of benzene in thinners were 0.25~1.18%. The benzene in enamel thinner, which were 0.39~0.72%, was highest from chemical classification. The contents of toluene, which was found from 27 kinds of thinners, were 5.35~64.16%, which were highest in sobu thinner as 58.80%. Xylene was found from 22 kinds of thinners and contents of xylene were 4.61~72.42%. Acrylic thinner's contents of xylene were 12.06~51.05%, which was most high. It was found that contents of benzene were increased and frequency of detection was decreased through comparison with other study. The MSDS possession rate of paint shops was low as 29.27%. So it did not provide information with public or workers. Mean of agreement rate between MSDS and components of thinners through qualitative analysis was 42.01% and it has wide range from 8.3% to 75%. There are many deficiencies in MSDS about component of thinners. In some case of sample, expecially, despite containing benzene, information was not written it on MSDS.

Trace Elements Analysis and Source Assessment of School Dust in Daegu, Korea (대구지역 학교먼지에 함유된 미량원소성분 분석과 오염원 평가)

  • Song, Hee-Bong;Do, Hwa-Seok;Lee, Myoung-Sook;Shin, Dong-Chan;Yoon, Ho-Suk;Kwak, Jin-Hee;Jung, Cheol-Su;Kang, Jae-Hyung
    • Journal of Korean Society of Environmental Engineers
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    • v.29 no.12
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    • pp.1390-1399
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    • 2007
  • Samples of 45 school dust were collected in Daegu in January 2007, were sieved below 100 ${\mu}m$, and 14 elements were analyzed using ICP after an acid extraction. Results obtained from the source assessment of trace elements using enrichment factor showed that dust from playground were influenced by natural sources, while dust from classroom were influenced by urban anthropogenic sources. The measured values were remarkably higher in components from natural sources than in components from urban anthropogenic sources. Dust from classroom are highly concentrated than those from playground. Concentrations of dust in urban area are similar to those of dust in rural area and there was no significant difference in concentrations between classroom with playground soil and classroom with play-ground grass. Compared with other cities in Korea, concentrations of heavy metals in Daegu city were higher in classroom and lower in playground than those of heavy metals in other cities. Dust from classroom contained lower concentrations of trace elements than those from street in Daegu. Results of pollution indices of heavy metals indicated that playground was not contaminated with heavy metals and classroom was considered to be highly contaminated. No appreciable differences in playground were found between urban and rural areas but in case of classroom pollution, heavy metal concentrations were a little bit higher in urban areas than in rural areas. The correlation analysis among trace elements indicated that components in playground were significantly correlated, while components in classroom were less correlated. Trace element components of classroom dust were not significantly affected by those of playground dust.

Residual Characteristics of some Pesticides in/on Pepper Fruits and Leaves by Different Types, Growing and Processing Conditions (재배환경, 품종 및 가공 방법에 따른 고추와 고춧잎 중 농약의 잔류 특성)

  • Lee, Hee-Dong;You, Oh-Jong;Ihm, Yang-Bin;Kwon, Hye-Young;Jin, Yong-Duk;Kim, Jin-Bae;Kim, Yun-Han;Park, Seung-Soon;Oh, Kyeong-Seok;Ko, Sung-Lim;Kim, Tae-Hwa;Noh, Jae-Goan;Kyung, Kee-Sung
    • The Korean Journal of Pesticide Science
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    • v.10 no.2
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    • pp.99-106
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    • 2006
  • Chlorothalonil and imidacloprid sprayed onto the green peppers were degraded more faster at outdoor than in greenhouse. These results were affected by dew and photodegration, considering no rain during the experimental period. Chlorothalonil, esfenvalerate and imidacloprid in green pepper, green twist pepper and sweet pepper did not show any residual pattern, because green peppers are one of the continuous harvesting crops and pesticides could not be sprayed homogeneously on them. When green peppers were pickled with soy sauce and green twist peppers were fried with vegetable oil, the amounts of pesticides such as alpha-cypermethrin, bifenthrin, chlorfenapyr, esfenvalerate and imidacloprid were diminished to the levels of about $30{\sim}71$ and $20{\sim}41%$, respectively. Esfenvalerate and imidacloprid could not be detected in 2 month-old hot pepper paste. The removal rates of pesticide residues in leaves of green peppers were about $22{\sim}37%$ by washing, about $74{\sim}95%$ by parboiling, and about $17{\sim}55%$ by drying after parboiling.

Changes in Physicochemical Characteristics during Soaking of Persimmon Pickles Treated with Organic Acids and Sugars (단감 장아찌의 저염 침지 중 유기산과 당의 종류에 따른 이화학적 특성의 변화)

  • Jeong, Do-Yeong;Kim, Yong-Suk;Jung, Sung-Tae;Shin, Dong-Hwa
    • Korean Journal of Food Science and Technology
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    • v.38 no.3
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    • pp.392-399
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    • 2006
  • In order to develop a new persimmon pickle with a low salt concentration, changes in physicochemical characteristics during soaking of persimmon pickles treated with different organic acids and sugars were investigated at $15^{\circ}C$ for 70 days. The pH of persimmon pickles decreased from pH 6.64 at initial stage to pH 3.99 (control group), pH 2.76-3.33 (citric acid treatment, CT), and pH 3.08-3.34 (acetic acid treatment, AT) after 70-days of soaking. Titratable acidity of AT was higher (0.86-1.18%) than that of CT (0.61-0.78%). After 70-days of soaking, salinity of persimmon pickles treated with stevia leaf powder, sodium saccharin, sucrose, and isomalto-oligosaccharide were 4.94-4.96, 4.00-5.15, 2.99-3.31, and 3.03-3.30%, respectively, and 1.54-3.70% lower than that of the control group (6.69%). The hardness of persimmon pickles in all cases was increased up to 20-40-days of soaking and then decreased. L (lightness), a (redness), and b (yellowness) value of persimmon pickles treated with citric acid were higher than those of AT and the control group. Sensory evaluation of persimmon pickles after 70-days of soaking revealed that CT had the highest scores for color, texture, and overall acceptability. These results indicate that the salt concentration of persimmon pickles could be lowered by the addition of citric acid and various sugars during soaking.

Yeast Selection and Comparison of Sterilization Method for Making Strawberry Wine and Changes of Physicochemical Characteristics during Its Fermentation (딸기주 발효를 위한 효모 선발과 살균 방법의 비교 및 발효 중 이화학적 특성의 변화)

  • Jeong, Eun-Jeong;Kim, Yong-Suk;Jeong, Do-Youn;Shin, Dong-Hwa
    • Korean Journal of Food Science and Technology
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    • v.38 no.5
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    • pp.642-647
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    • 2006
  • Yeast selection and the sterilization methods of strawberry juice were optimized for making strawberry wine. In addition, changes in the physicochemical characteristics of the wine during its fermentation were estimated. Maehyang and Yukbo cultivars of strawberry were tested for wine making; they contained 9.8 and 9.3% soluble solids and 0.59 and 0.58% titratable acidities, respectively. Among six yeasts tested, the Wg-15 and Sc-51 strains were selected based on the alcohol yield in the strawberry wine. Alcohol and soluble solid contents following heat treatment ($85^{\circ}C$, 10 min) or $K_2S_2O_5$ (200 ppm) treatment for sterilization were 7.10-7.20% and 5.60-5.80%, respectively, and no differences were observed between the Wg-15 and the Sc-51 strains. However, the flavor of wine produced following heat treatment was slightly better than that following $K_2S_2O_5$ treatment. The greatest amounts of alcohol were produced after 2 days of fermentation at $26^{\circ}C$. The alcohol content in wines produced with 12, 14, and 16% sugar content in the initial stages were 5.1, 6.0-6.2, and 7.5-7.7%, and the soluble solid contents were 3.9-4.3, 4.1-4.3, and 5.0-5.3%, respectively; no significant differences were observed between the Wg-15 and the Sc-51 yeast strains. For making strawberry wine, we proposed that the sugar content of Maehyang or Yukbo cultivars be adjusted to 16% soluble solids in the initial stages with heat treated at $85^{\circ}C$ for 10 min and fermentation with the Wg-15 or Sc-51 yeast strains at $26^{\circ}C$ for 8 days.

Study on Temporal Decay Characteristics of Naturally Occurring Radionuclides in Groudwater in Two Mica Granite Area (복운모화강암지역 지하수 중 자연방사성 물질의 경시적 붕괴특성 연구)

  • Kim, Moon Su;Kim, Tae Seung;Kim, Hyun Koo;Kim, Dong Su;Jeong, Do Hwan;Ju, Byoung Kyu;Hong, Jung Ki;Kim, Hye Jin;Park, Sun Hwa;Jeong, Chan Ho;Cho, Byong Wook;Han, Jin Seok
    • Journal of Soil and Groundwater Environment
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    • v.18 no.4
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    • pp.19-31
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    • 2013
  • To figure out the decay characteristics of naturally occurring radionuclides, eight sampled groundwaters from a monitoring borehole having high levels of uranium and radon concentrations in a two mica granitic area have analyzed by liquid scintillation counters (LSC) for over 1 year. In December 2011, three groundwater samples (DJ1, DJ2, DJ3) were obtained from each aquifer system located at -20 m, -40 m, -60 m of the monitoring borehole below the ground surface, respectively. Five samples (DJ4, DJ5, DJ6, DJ7, DJ8) were additionally gained from each aquifer positioned -20 m, -40 m, -60 m, -100 m, -105 m of the borehole in February 2012, respectively. Temporal variation characteristics of uranium and radon concentrations have showed over maximum 2.1 times and 1.4 times fluctuations of the values in the same sampling intervals over time, respectively. The intervals of -40 m and -105 m in the borehole have the highest values of uranium and radon concentrations, respectively. This may imply that the concentrations of naturally occurring radionuclides such as uranium and radon in groundwater have been changed over time and indicate that the qualities of groundwaters from the aquifers developed at each interval in the borehole are different each other. This discrepancy, moreover, could be caused by behaviour differences between uranium which is in ionic status having a half life of 4.6 billion years and is transported along with the flowing groundwater, and radon which is in gaseous status having a 3.82 day's half life in the aquifer systems. Physicochemical characteristics of groundwaters from the aquifer systems could be identified by the results of the on-situ measuring items such as pH and Eh, and the major ionic contents. The CPM values of eight groundwater samples analysed by LSC over one year have shown not to follow the theoretical decay curve of the radon. The CPM values of the samples have ranged from 2 to 7.5 after it had passed two months when the theoretical CPM values of the radon started zero since the initial analysis. Alpha and beta particle spectrums have shown the peaks of radium-226, however they have not revealed any peaks of radon and it's daughter products such as polonium-218 and 214, bismuth-214 for the late stage of the analysis. This implies that the groundwater from the borehole may contain radium-226 having a half life of 1,600 years which decays continuously.

A Study of the Garden Remains in Mountain Bukak in Dohwadong, Seoul (서울 북악산 도화동 원림유적에 대한 고찰)

  • Kim, Hong-Gon;Kim, Young-Mo
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.28 no.1
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    • pp.66-80
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    • 2010
  • In this thesis, the garden remains in Dohwadong which is located in Seoul Buk-ak Mountain was examined, together with reference discovery and historical research, and onsite academic research conducted, for the purpose of studying the location of the garden remains in Dohwadong, its historical transitions and original landscape. As a result of the study, the location of the garden remains in Dohwadong was found; through the research of relevant historical sources, its historical transitions, its original landscape, and the value it has as a garden remains were examined. The following is the summary of the original form of the garden remains in Dohwadong and the value it has as a garden remains derived from this study. First, the garden remains in Dohwadong had earlier known as a remains related to the housing site of Namgon or Daeunahm. However, it has been verified that is it Dohwadong which is an original word of a royal family formed by King Kojong's order in 1889 since the characters carved on rocks which is recorded in the book of "Chong Sweh Rok" perfectly conform to those within the garden remains in Dohwadong. Second, it was learned that Dohwadong was the greatest renowned place for entertaining next to Pilundae; according to the book of "Hankyung Jiryak", the name, Dohwadong, is known to have come from the fact that there are a large number of peach trees in the area; the records of those books, "Ahjungyugoh", "Yonahmjip", etc., also state that literary men gathered in Dohwadong and held ceremonies and entertained. Third, it was learned that the garden remains in Dohwadong had been used as a place for holding ceremonies by the Ahndong Kims including Myonggongsukhyon; after Heungsundaewongun's governance, it was removed and neglected as the Ahndong Kims were purged and changed into a place for the royal family by the command of King Kojong in 1889. Fourth, Dohwadong followed the geographical features of nature, embraced the elegant surrounding scenery naturally, and gave significance to the sceneries of the season and its element and, in this way, it, as an ideal landscape model, is a valuable garden remains which realized the symbolic Dohwa landscape and presents its original scenery of the traditional garden. As mentioned above, this study, based on historical sources, has made progress in understanding the truth of the garden remains in Dohwadong and its value as a garden remains through the onsite research and academic historical investigation. However, since it is located within a military region, research was limitedly made. And also the range and structure of the garden remains was difficult to examine. Overall excavation is needed to figure out the remains and original terrain. Accordingly, in order to find out the truth of the garden remains in Dohwadong and for further preservation and application, it needs to be designated as a historical site and additional academic excavation research needs to be conducted; maintenance and preservation policies including removal of the cement and embankment, which disturb the original terrain within the remains, also need to be carried out.