• 제목/요약/키워드: Dmc1

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Septo-optic dysplasia associated with chromosome 15q13.3 duplication: a case report

  • Jeong A Ham;Sung Hyun Kim;Donghwi Park
    • Journal of Yeungnam Medical Science
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    • v.40 no.4
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    • pp.419-422
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    • 2023
  • Septo-optic dysplasia (SOD) is a rare congenital anomaly that is clinically defined by developmental delay and characteristic brain magnetic resonance imaging findings, including optic nerve hypoplasia, pituitary hormone abnormalities, and midline brain defects. The occurrence of SOD is generally sporadic; however, it can be inherited rarely. Although an association with HESX1, SOX2, and SOX3 mutations has been identified, the detailed etiology is multifactorial and unclear. Here, we present the case of a 7-year-old girl who was clinically diagnosed with SOD and 15q13.3 duplication. Patients with duplication at chromosome 15q13.3 were reported to be diagnosed with autism spectrum disorder, epilepsy, and schizophrenia in previous studies. The relationship between SOD and the microduplication of 15q13.3 has not yet been explored. In this study, we suggest that there may be an association between chromosome 15q13.3 microduplication and SOD.

Organic Electrolyte of the Additive the Gamma-Butyroloctone (GBL) for Additive Material Application to High Voltage Electrochemical Capacitor (Gamma-butyroloctone(GBL)을 첨가한 유기계 전해액의 고전압용 전기화학 커패시터로의 응용)

  • You, Sun-Kyung;Park, Soo-Gil
    • Journal of the Korean Electrochemical Society
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    • v.20 no.1
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    • pp.13-17
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    • 2017
  • In this study, we studied the organic electrolyte application to electrochemical capacitor for high operation voltage. For high operating voltage, 5 wt % of gamma butyroloctone (GBL) was added in the bare electrolyte. During the cycle performance, stable SEI layers were formed by reductive decomposition of additive GBL. As a result, columbic efficient of 1M $SBPBF_4$ in EC:DMC(1:1) with GBL composite was enhanced to 70% after the 2000th cycle at voltage range 0-3.5 V. Additionally, SEI layer protected the surface of electrode and prevent the side-reaction between electrolyte to electrode.

Hed1 Promotes Meiotic Crossover Formation in Saccharomyces cerevisiae

  • Kong, Yoon-Ju;Joo, Jeong-Hwan;Kim, Keun Pil;Hong, Soogil
    • Journal of Microbiology and Biotechnology
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    • v.27 no.2
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    • pp.405-411
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    • 2017
  • Homologous recombination occurs between homologous chromosomes and is significantly involved in programmed double-strand break (DSB) repair. Activation of two recombinases, Rad51 and Dmc1, is essential for an interhomolog bias during meiosis. Rad51 participates in both mitotic and meiotic recombination, and its strand exchange activity is regulated by an inhibitory factor during meiosis. Thus, activities of Rad51 and Dmc1 are coordinated to promote homolog bias. It has been reported that Hed1, a meiosis-specific protein in budding yeast, regulates Rad51-dependent recombination activity. Here, we investigated the role of Hed1 in meiotic recombination by ectopic expression of the protein after pre-meiotic replication in Saccharomyces cerevisiae. DNA physical analysis revealed that the overexpression of Hed1 delays the DSB-to-joint molecule (JM) transition and promotes interhomolog JM formation. The study indicates a possible role of Hed1 in controlling the strand exchange activity of Rad51 and, eventually, meiotic crossover formation.

A Kinetic Study on the Synthesis of Dimethylcarbonate by Using Immobilized Ionic Liquid Catalyst (고정화된 이온성 액체 촉매를 이용한 디메틸카보네이트 합성 반응에 대한 속도론적 고찰)

  • Kim, Dong-Woo;Kim, Dong-Kyu;Kim, Cheol-Woong;Koh, Jae-Cheon;Park, DaeWon
    • Korean Chemical Engineering Research
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    • v.48 no.3
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    • pp.332-336
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    • 2010
  • Ionic liquid immobilized on mesoporous amorphous silica was prepared from the coupling of 1-(triethoxysilylpropyl)-3-n-alkyl-imidzolium halides with tetraethyl orthosilicate(TEOS) through template-free condensation under strong acidic conditions. The immobilized 1-n-butyl-3-methyl imidazolium bromide ionic liquid on amorphous silica(BMImBr-AS) was proved to be an effective heterogeneous catalyst for the synthesis of dimethyl carbonate(DMC) from transesterification of ethylene carbonate(EC) with methanol. High temperature, high carbon dioxide pressure and long reaction time were favorable for the reactivity of BMImBr-AS. Kinetic studies based on two step reactions revealed that the proposed reaction model fitted well the experimental data. The apparent activation energy was estimated to be 67.4 kJ/mol.

Cycling Performance and Surface Chemistry of Si-Cu Anode in Ionic Liquid Battery Electrolyte Diluted with Dimethyl Carbonate

  • Nguyen, Cao Cuong;Kim, Dong-Won;Song, Seung-Wan
    • Journal of Electrochemical Science and Technology
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    • v.2 no.1
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    • pp.8-13
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    • 2011
  • Interfacial compatibility between the Si-Cu electrode and diluted ionic liquid electrolyte containing 50 vol.% of 1M lithium bis(trifluoromethanesulfonyl)imide (LiTFSI)/1-methyl-1-propylpyrrolidinium bis(trifluoromethylsulfonyl)imide (MPP-TFSI) and 50 vol.% dimethyl carbonate (DMC) in a lithium cell and dilution effect on surface chemistry are examined. ex-situ ATR FTIR analysis results reveal that the surface of the Si-Cu electrode cycled in the diluted ionic liquid electrolyte is effectively passivated with the SEI layer mainly composed of carboxylate salts-containing polymeric compounds produced by the decomposition of DMC. Surface species by the decomposition of TFSI anion and MPP cation are found to be relatively in a very low concentration level. Passivation of electrode surface with the SEI species contributes to protect from further interfacial reactions and to preserve the electrode structure over 200 cycles, delivering discharge capacity of > 1670 $mAhg^{-1}$ and capacity retention of 88% of maximum discharge capacity.

A Study on Implementation of 3D Player based on MPEG-4 Using Java Language (Java언어를 이용한 MPEG-4기반 3차원 플레이어의 구현에 관한 연구)

  • Park Young-Kyung;Kim Yong-Ho;Jung Jong-Jin;Kim Joong-Kyu;Ahn Sang-Woo;Choi Jin-Soo;Kim Jin-Woong;Ahn Chie-Teuk
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.29 no.1B
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    • pp.117-124
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    • 2004
  • With MPEG-4 3D mesh coding(3DMC), the problem of the need of a wide bandwidth can be solved to store and transmit 3D information because of its high compression rate. And to realize the 3D information service with broadcasting or internet, one needs to transmit not only the 3D contents but also the 3D player. Therefore, in this paper we implement a 3D player based on MPEG-4 using a java language. A well-known java language employed in this paper provides the player with a wider range of applications, for example, when the O/S or the platform are different, due to its properties of scalability and universality. The implemented player which has functions (translation, rotation, etc) that can manipulate contents decodes the 3D contents and displays them. In addition, the player has a network function that receives a 3D content from the server. This paper explains the architecture and characteristics of the player and shows its simulation results.

Totem-pole Bridgeless Boost PFC Converter Based on GaN FETs (GaN FET을 이용한 토템폴 구조의 브리지리스 부스트 PFC 컨버터)

  • Jang, Paul;Kang, Sang-Woo;Cho, Bo-Hyung;Kim, Jin-Han;Seo, Han-Sol;Park, Hyun-Soo
    • The Transactions of the Korean Institute of Power Electronics
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    • v.20 no.3
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    • pp.214-222
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    • 2015
  • The superiority of gallium nitride FET (GaN FET) over silicon MOSFET is examined in this paper. One of the outstanding features of GaN FET is low reverse-recovery charge, which enables continuous conduction mode operation of totem-pole bridgeless boost power factor correction (PFC) circuit. Among many bridgeless topologies, totem-pole bridgeless shows high efficiency and low conducted electromagnetic interference performance, with low cost and simple control scheme. The operation principle, control scheme, and circuit implementation of the proposed topology are provided. The converter is driven in two-module interleaved topology to operate at a power level of 5.5 kW, whereas phase-shedding control is adopted for light load efficiency improvement. Negative bias circuit is used in gate drivers to avoid the shoot-through induced by high speed switching. The superiority of GaN FET is verified by constructing a 5.5 kW prototype of two-module interleaved totem-pole bridgeless boost PFC converter. The experiment results show the highest efficiency of 98.7% at 1.6 kW load and an efficiency of 97.7% at the rated load.

Electrochemical Properties of LiMnO2-organic Composite Cathodes with High Capacity for Lithium Ion Polymer Battery (리튬 이온 폴리머 전지용 고용량 LiMnO2-organic Composite 정극의 전기화학적 특성)

  • 김종욱;조영재;구할본
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.15 no.2
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    • pp.162-168
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    • 2002
  • The purpose of this study is to research and develop LiMnO$_2$-organic and Li$_{0.3}$MnO$_{2}$-organic composite with high energy density for Lithium ion polymer battery. This paper describes cyclic voltammetry, impedance sepctroscopy, electrochemical properties of LiMnO$_2$-organic and Li$_{0.3}$MnO$_{2}$-organic composite with polymer electrolyte as a function of a mixed ratio. The first discharge capacity of LiMnO$_2$-PAn with 3 wt.% PAn was 83mHA/g, while that of Li$_{0.3}$MnO$_{2}$-PPy composite was 136 mAh/g. The Ah efficiency was above 98% after the 2nd cycle. The LiMnO$_2$-PAn with DMcT 2 wt.% and Li$_{0.3}$MnO$_{2}$-PPy composites cathode with 5wt. PPy in PVDF-PC-EC-LiClO$_4$ electrolyte showed good capaity with cycling. The discharge capacity of LiMnO$_2$-PAn with wt.% DMcT was 80 and 130 mAh/g at 1st and 12th cycle, respectively. The capacity of LiMnO$_2$-PAn composite with 2 wt.% DMcT was higher than that of LiMnO$_2$-PAn composite.mposite.

Dislocation after Revision Total Hip Arthroplasty: A Comparison between Dual Mobility and Conventional Total Hip Arthroplasty

  • Hyun Sik Shin;Dong-Hong, Kim;Hyung Seok Kim;Hyung Seob Ahn;Yeesuk Kim
    • Hip & pelvis
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    • v.35 no.4
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    • pp.233-237
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    • 2023
  • Purpose: The objective of this study was to analyze the results from a cohort of patients who underwent a revision total hip arthroplasty (THA) using a dual mobility cup (DMC) implant. Materials and Methods: A retrospective review of revised THAs was conducted using the database from a single tertiary referral hospital. A total of 91 revision THAs from 91 patients were included in the study. There were 46 male hips and 45 female hips. The mean age was 56.3±14.6 years, and the mean follow-up period was 6.4±5.9 years. In performance of revision THAs, the DMC implants were used in 18 hips (19.8%), and the conventional implants were used in 73 hips (80.2%). Results: During the follow-up period, three dislocations were identified, and the overall dislocation rate was 3.3%. Early dislocation (at one month postoperatively) occurred in one patient, while late dislocation (at a mean of 7.5 years) occurred in two patients. There was no occurrence of dislocation in the DMC group (0%), and three dislocations were detected in the conventional group (4.1%). However, no significant difference in the rate of dislocation was observed between the two groups (P=0.891). Conclusion: Although the rate of dislocation was higher in the conventional group, there were no statistically significant differences between the two groups due to the small number of patients. Nevertheless, we believe that the dual mobility design is advantageous in terms of reducing dislocation rate and can be recommended as an option for a revision THA.

DAB 정책방향

  • 조광휘
    • Broadcasting and Media Magazine
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    • v.8 no.1
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    • pp.4-11
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    • 2003
  • 방송위원회는 산하 특별위원회로 운영한 2002년 디지털 방송추진위원회(제3기)의 논의사항을 토대로 최근 'DMB.데이터방송 및 DMC 등 디지털방송에 관한 종합계획'(심의의결: 2003년 2월 24일)을 마련하였다. 그 내용중 DMB 부문에 대한 방송위원회의 정책수립 배경과 결정사항을 설명하고자 한다.