• Proceedings of the Korean Society of Embryo Transfer Conference
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• 2002.11a
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• pp.118-118
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• 2002

Programmed cell death (PCD) is thought as a well-controlled process by which unwanted cells are selectively eliminated. During the last decade many researches have elucidated molecules and their interactions involved in cell death by using largely in vitro induction of cell death or survival signals in a more defined manner, While these critical information and novel findings provide us with clearer understanding of mechanisms underlying cell death, it does by no means explain how PCD occurs and which cells or tissues are affected during normal embryonic development in vivo. In this study, we used zebrafish to examine whether the PCD is occurring selectively or randomly in developing embryos by whole mount in situ TUNEL analysis with specific markers for neural cells. The result revealed that the degree and distribution of TUNEL staining varied considerably throughout gastrulation stage, and there was also a number of TUNEL-negative embryos. Most of TUNEL-positive cells were scattered randomly throughout the blastoderm. During the gastrulation stage about 75 % of the embryos analyzed exhibited more than 5 TUNEL-positive cells. As the dorsal epiblast begins to thicken rather abruptly near the end of gastrulation, TUNEL-positive cells were mainly located along the dorsal side. Although there were some variations in TUNEL staining during segmentation and pharyngeal stages, TUNEL staining continued to be localized to the central nervous system, and was also detected in the sensory organs, trigeminal ganglions, and the primary sensory neurons. High levels of the cell death in developing brain between 20-somite and prim-6 stages are thought to play a role in the morphogenesis and organization of the brain. At prim-16 stage, cell death is considerably reduced in the brain region. Dying cells are mainly localized to the prospective brain region where ectodermal cells are about to initiate neurogenesis. As development progressed, high levels and more reproducible patterns of cell death were observed in the developing nervous system. Intensive TUNEL staining was restricted to the trigeminal ganglions, the primary sensory neurons, and sensory organs, such as olfactory pits and otic vesicles. Thus, PCD patterning in zebrafish embryos occurs randomly at early stages and becomes restricted to certain region of the embryos. The spatio-temporal pattern of PCD during the early embryonic development in zebrafish will provide basic information for further studies to elucidate genes involved in. regulation of PCD largely unknown in vivo during vertebrate embryogenesis.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.41 no.8
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• pp.9-18
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• 2004

The IEEE 802.11 Distributed Coordination Function(DCF) protocol provides a contention-based distribution channel access mechanism for stations to share the wireless medium. However, the performance of the DCF drops dramatically in terms of throughput, delay and delay jitter as the number of active stations becomes large. In this paper, we propose a simple and effective scheme, called DCF/VG(Distributed Coordination Function with Virtual Group), for improving the performance of the IEEE 802.11 DCF mechanism. In this scheme, each station independently decides the virtual group cycle using the information provided by the carrier sensing mechanism. The virtual group cycle consists of one or more virtual groups and a virtual group includes an idle period and a busy period. Each station operates in only one out of several virtual groups of the virtual group cycle and does not operate in the others. In other words, each station decreases its backoff counter and tries to transmit a packet only in its virtual group like the IEEE 802.11 DCF. Performance of the proposed scheme is investigated by numerical analysis and simulation. Numerical and simulation results show that the proposed scheme is very effective and has high throughput and low delay and jitter under a wide range of contention level.

• Journal of the Institute of Electronics and Information Engineers
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• v.53 no.5
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• pp.19-24
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• 2016

In Long Term Evolution-Advanced (LTE-A), small cell enhancement(SCE) has been developed as a cost-effective way of supporting exponentially increasing demand of wireless data services and satisfying the user quality of service(QoS). However, due to the dense and irregular distribution of a large number of small cells, the offloading scheme should be applied in the small cell network. In this paper, we propose an user offloading scheme for SCE in LTE-Advanced system. We divide the small cells into different clusters according to the reference signal received power(RSRP) from user equipment(UE). Within a cluster, We apply the user offloading scheme with the consideration of the number of users and interference conditions. Simulation results show that proposed scheme can improve the throughput, and spectral efficiency of small cell users. Eventually, proposed scheme can improve overall cell performance.

• Journal of the Institute of Electronics and Information Engineers
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• v.53 no.5
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• pp.13-18
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• 2016

In Long Term Evolution-Advanced (LTE-A), small cell enhancement(SCE) has been developed as a cost-effective way of supporting exponentially increasing demand of wireless data services and satisfying the user quality of service(QoS). However, there are many problems such as the transmission rate and transmission quality degradation due to the dense and irregular distribution of a large number of small cells. In this paper, we propose a clustering based interference management scheme in dense small cell network. We divide the small cells into different clusters according to the reference signal received power(RSRP) from user equipment(UE). Within a cluster, an almost blank subframe(ABS) is implemented to mitigate interference between the small cells. In addition, we apply the power control to reduce the interference between the clusters. Simulation results show that proposed scheme can improve Signal to Interference plus Noise Ratio(SINR), throughput, and spectral efficiency of small cell users. Eventually, proposed scheme can improve overall cell performance.

• Journal of the Institute of Electronics and Information Engineers
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• v.52 no.3
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• pp.213-220
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• 2015

Wireless sensor network(WSN) is made up of a lot of battery operated inexpensive sensors that, once deployed, can not be replaced. Therefore, energy efficiency of WSN is essential. Among the methods for energy efficiency of the network, clustering algorithms, which divide a WSN into multiple smaller clusters and separate all sensors into cluster heads and their associated member nodes, are very energy efficient routing technique. The first cluster-based routing protocol, LEACH, randomly elects the cluster heads in accordance with the probability. However, if the distribution of selected cluster heads is not good, uniform energy consumption of cluster heads is not guaranteed and it is possible to decrease the number of active nodes. Here we propose a new routing scheme that, by comparing the remaining energy of all nodes in a cluster, selects the maximum remaining energy node as a cluster head. Because of decrease in energy gap of nodes, the node that was a cluster head operates as a member node much over. As a result, the network lifespan is increased and more data arrives at base station.

• Journal of the Institute of Electronics and Information Engineers
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• v.52 no.8
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• pp.67-73
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• 2015

In a distribution of digital image, there is a serious problem that is the image alteration by a forger. For the problem solution, this paper proposes the forensic decision algorithm of a median filtering (MF) image using the feature vector based on a coefficient of variation (c.v.) of Fourier transform. In the proposed algorithm, we compute Fourier transform (FT) coefficients of row and column line respectively of an image first, then c.v. between neighboring lines is computed. Subsquently, 10 Dim. feature vector is defined for the MF detection. On the experiment of MF detection, the proposed scheme is compared to MFR (Median Filter Residual) and Rhee's MF detection schemes that have the same 10 Dim. feature vector both. As a result, the performance is excellent at Unaltered, JPEG (QF=90), Down scaling (0.9) and Up scaling (1.1) images, and it showed good performance at Gaussian filtering ($3{\times}3$) image. However, in the performance evaluation of all measured items of the proposed scheme, AUC (Area Under ROC (Receiver Operating Characteristic) Curve) by the sensitivity and 1-specificity approached to 1 thus, it is confirmed that the grade of the performance evaluation is rated as 'Excellent (A)'.

• Journal of the Korean earth science society
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• v.26 no.5
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• pp.436-442
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• 2005

We have performed multiple geophysical surveys comprised of gravity, magnetic and resistivity methods at the Yangsan fault zone which runs through the Eonyang area, the eastern part of Kyeongsang in southeast Korea. The gravity and magnetic data provide information about geological structures. Furthermore, sections of electrical resistivity show the sharp contrast of electrical resistivity distribution across the fault zone. Since the fractured zone tends to be more conductive than fresh host rocks, the electrical resistivity survey is effective in determining the detailed structure of the fault zone. We have made gravity measurements at a total of 71 points alongside two profiles across the fault zone, and carried out an electrical resistivity survey with a dipole-dipole array at the same location using 40m dipole length. In addition, we have analyzed the aeromagnetic data on the corresponding area. The multiple geophysical properties appear to be abruptly changed in electrical resistivity, gravity and aeromagneticclearly show the different appearance across the fault zone. The fault is identified by its sub vertical attitude which is well known in the Yangsan fault zone. We have also confirmed that the magnitude of the response of the fault is much larger in the southern part of the survey area than the northern area. These results most likely to provide basic information for the further studies about the physical properties and the structures at the Yangsan fault.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.23 no.5
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• pp.897-907
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• 2013

Since various smart devices are being developed, a growing number of people are reading eBooks instead of paper books. However, people started making eBooks on their own by scanning paper books because there are not enough eBooks provided from market. The term "Bookscan" was made with this reason. The number of bookscan company is increasing because the equipment is too expensive. However, the commercial activity of bookscan company is against copyright law. Also bookscan files are in danger of being illegally distributed on web, because bookscan companies are not protecting copyright. Publication market follows the same procedure with sound market which was collapsed due to copyright problem. Therefore, the technical methods should be prepared for law system against bookscan. The previous ICOP(Illegal Copyrights Obstruction Program) system has been applied to sound and movie files, but not applied to publication. This paper suggests the framework for bookscan file management based on practical mechanism.

• Journal of the Korean GEO-environmental Society
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• v.19 no.5
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• pp.23-31
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• 2018

The dredging project became more important with the recent construction of off shore structures and reclamation projects. Accordingly, more exact quantitative estimation of the dredged amount should be required. The sub-sea ground information can be obtained generally by the boring investigation and the dredged amount can be estimated based on the depth or the deeper bound of a ceratin layer via 3D visualization program. During the estimation process, the input DB should be constructed with 1D elevation information from boring investigation for the spatially approximated distribution of a deeper bound of each ground layer. The input DB can be varied with the application of the borings and the approximation targets. Therefore, the 3D visualized ground profile and dredged amounts are compared on the actively dredged sites, vicinity of Saemangeum area and outer port area in Gunsan with regard to the input DB construction methods. Conclusively, the input DB based on the spatially approximated depths show higher precision results and more reasonable 3D visualized ground profiles.

• Genomics & Informatics
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• v.5 no.1
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• pp.10-18
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• 2007

Numerous studies have reported that genes with similar expression patterns are co-regulated. From gene expression data, we have assumed that genes having similar expression pattern would share similar transcription factor binding sites (TFBSs). These function as the binding regions for transcription factors (TFs) and thereby regulate gene expression. In this context, various analysis tools have been developed. However, they have shortcomings in the combined analysis of expression patterns and significant TFBSs and in the functional analysis of target genes of significantly overrepresented putative regulators. In this study, we present a web-based A Functional Clustering Analysis Tool for Predicted Transcription Regulatory Elements and Gene Ontology Terms (FCAnalyzer). This system integrates microarray clustering data with similar expression patterns, and TFBS data in each cluster. FCAnalyzer is designed to perform two independent clustering procedures. The first process clusters gene expression profiles using the K-means clustering method, and the second process clusters predicted TFBSs in the upstream region of previously clustered genes using the hierarchical biclustering method for simultaneous grouping of genes and samples. This system offers retrieved information for predicted TFBSs in each cluster using $Match^{TM}$ in the TRANSFAC database. We used gene ontology term analysis for functional annotation of genes in the same cluster. We also provide the user with a combinatorial TFBS analysis of TFBS pairs. The enrichment of TFBS analysis and GO term analysis is statistically by the calculation of P values based on Fisher’s exact test, hypergeometric distribution and Bonferroni correction. FCAnalyzer is a web-based, user-friendly functional clustering analysis system that facilitates the transcriptional regulatory analysis of co-expressed genes. This system presents the analyses of clustered genes, significant TFBSs, significantly enriched TFBS combinations, their target genes and TFBS-TF pairs.