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The convergence effect of phenylephrine, isoprenaline and prazosin on vascular contractility (혈관 수축성에 대한 phenylephrine, isoprenaline 및 prazosin의 융합성 조절 효과)

  • Je, Hyun Dong;Min, Young Sil
    • Journal of Convergence for Information Technology
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    • v.12 no.4
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    • pp.119-125
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    • 2022
  • In the study, we endeavored to investigate the effect of phenylephrine, isoprenaline and prazosin on the tissue-specific vascular contractility and to determine the mechanism involved. There were few reports addressing the question whether thin or thick filament modulation is included in phenylephrine, isoprenaline and prazosin-induced regulation. We hypothesized that isoprenaline and prazosin play a role in tissue-dependent regulation of vascular contractility. Denuded arterial muscles of Sprague-Dawley male rats were suspended in organ baths and isometric tensions were transduced and recorded using isometric transducers and an automatic data acquisition system. Interestingly, sustained continuous contraction of thoracic and abdominal aorta. Furthermore, isoprenaline and prazosin together with phenylephrine inhibited transiently and persistently vasoconstriction of thoracic and abdominal aorta suggesting that additional mechanisms (e.g. decreased receptor density, chemical interaction, postreceptor signaling or distribution of agonists) might be included in the modulation of vascular contractility.

Quality Improvement Strategy Development based on Competitor Analysis of Manufacturing Companies: Application to the Dashboard Camera Market (제조업 경쟁사 분석을 통한 품질 개선 전략 수립: 대시보드 카메라 시장에 적용)

  • Kang, Chang Dong;Choi, Il Young;Kim, Jae Kyeong;Park, Jae Seung
    • Journal of Information Technology Services
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    • v.21 no.2
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    • pp.27-41
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    • 2022
  • In a fiercely competitive environment, quality is a key factor that enables dashboard camera makers to maintain their competitive advantage. Quality affects consumer satisfaction, brand loyalty, and firm performance. Therefore, to remain competitive, it is important that manufacturers maintain product quality that meets consumer expectations. To this end, it is necessary to investigate customer preferences and product performance in terms of product quality and to properly allocate resources to improve the quality level such that the firm can maintain a competitive advantage. In this paper, we proposed the various ways in which manufacturing firms can determine which quality dimensions need improvement in order to secure competitiveness. To this end, we analyzed a case study of Urive to develop a quality improvement strategy through importance performance competitor analysis (IPCA). Urive's IPCA results showed that 14 quality dimensions, namely performance, size, price, ease of use, country of origin, manufacturer, brand, product certificate, warranty, distribution channel, market share, reliability, durability, and conformance, were not absolutely competitive compared with those of Mando, Inavi, and Finevu. In terms of color, Urive had an absolute competitive advantage over Mando, but not Inavi and Finevu. Urive's appearance was more competitive than Mando's, but not Inavi's and Finevu's. In terms of advertisement and serviceability, Urive was absolutely less competitive than Mando and Inavi, but had a competitive advantage over Finevu. Therefore, it is necessary to put resources and time as the first priority for performance, reliability, and durability, which have a large performance difference in common among the three brands. The quality dimensions in which resources and time need to be put in second place are price and ease of use, which have a large performance difference in common among the two brands.

Reference dosimetry for inter-laboratory comparison on retrospective dosimetry techniques in realistic field irradiation experiment using 192Ir

  • Choi, Yoomi;Kim, Hyoungtaek;Kim, Min Chae;Yu, Hyungjoon;Lee, Hyunseok;Lee, Jeong Tae;Lee, Hanjin;Kim, Young-su;Kim, Han Sung;Lee, Jungil
    • Nuclear Engineering and Technology
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    • v.54 no.7
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    • pp.2599-2605
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    • 2022
  • The Korea Retrospective Dosimetry network (KREDOS) performed an inter-laboratory comparison to confirm the harmonization and reliability of the results of retrospective dosimetry using mobile phone. The mobile phones were exposed to 192Ir while attached to the human phantoms in the field experiment, and the exposure doses read by each laboratory were compared. This paper describes the reference dosimetry performed to present the reference values for inter-comparison and to obtain additional information about the dose distribution. Reference dosimetry included both measurement using LiF:Mg,Cu,Si and calculation via MCNP simulation to allow a comparison of doses obtained with the two different methodologies. When irradiating the phones, LiF elements were attached to the phones and phantoms and irradiated at the same time. The comparison results for the front of the phantoms were in good agreement, with an average relative difference of about 10%, while an average of about 16% relative difference occurred for the back and side of the phantom. The differences were attributed to the different characteristics of the physical and simulated phantoms, such as anatomical structure and constituent materials. Nevertheless, there was about 4% of under-estimation compared to measurements in the overall linear fitting, indicating the calculations were well matched to the measurements.

Structural and Dynamic Analysis of a Unmanned Cargo Multicopter Using Hybrid Power System (하이브리드 추진 시스템을 이용한 수송용 멀티콥터 무인기의 구조 및 동특성 해석)

  • Kee, Youngjung;Kim, Taekyun
    • Journal of Aerospace System Engineering
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    • v.16 no.5
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    • pp.78-85
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    • 2022
  • Multicopter-type unmanned aerial vehicles (UAV) are increasingly for cargo transportation to mountainous and island regions, image information acquisition in disaster areas, and emergency rescue transport. In order to successfully perform these tasks, the aircraft structure must be able to safely support the loads induced by flight conditions while ensuring the vibration and aeroelastic stability of the prop-rotor. This study introduced a structural analysis model of a 40kg payload multicopter with an engine-generator hybrid power system. The deformation and stress distribution are investigated depending on the load conditions. In addition, the vibration characteristics and aeroelastic stability of the prop-rotor were also presented to flight speed and aircraft pitch angle. The maximum thrust generated by the prop-rotor and the landing load applied to the multicopter under normal and emergency landing conditions were reviewed., It confirmed that the structure could support without failure. In addition, it confirmed that the damping characteristics of each primary locate in the constant region according to the aircraft's flight speed and the prop-rotors rotating speed.

Aspects of the growth and reproductive biology of Oreochromis niloticus (Linnaeus, 1758) in a tropical Soda Lake, Lake Shala, Ethiopia

  • Wagaw, Solomon;Mengistou, Seyoum;Getahun, Abebe
    • Fisheries and Aquatic Sciences
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    • v.25 no.7
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    • pp.380-389
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    • 2022
  • Morphometric relationships, condition factor (CF) and reproductive biology are significant tools in fish stock management, fish biology, physiology, conservation and ecology. Growth and reproductive strategy of Oreochromis niloticus were studied from 343 fish specimens collected from Lake Shala between January and December 2018. Fish samples ranged from 7.7 cm to 33.0 cm in total length (TL) and from 7.80 g to 708.21 g in total weight (TW) were collected using gillnets of 4, 6, 8, 10, and 12 mm mesh sizes. The length-weight relationship of O. niloticus was TW = 0.0104TL3.19, indicating positive allometric growth of the fish. The sex ratio (0.93:1) was insignificant from the ideal fish distribution of 1:1 (χ2 = 0.47, p > 0.05). Mean CF for males, females and combined sexes was 1.04, 1.06 and 1.05, respectively and statistically insignificant (p > 0.05). The spawning peak occurred in July (rainy) and February (dry) periods, as defined by ripe females and the breeding season. Absolute mean fecundity was 806 eggs and correlated positively with TL and TW of the fish (p < 0.05) (F = 0.56TL2.29, R2 = 0.93, p < 0.05; F = 18.83TW0.67, R2 = 0.90, p < 0.05). The study provides the first detailed account of the morphometric relationships and reproductive biology of O. niloticus in Lake Shala, which can be used as baseline information for successive biological-based studies in Soda Lakes of Ethiopia.

The Impact of COVID-19 on the Volatility of Bangladeshi Stock Market: Evidence from GJR-GARCH Model

  • GOLDER, Uttam;RUMALY, Nishat;SHAHRIAR, A.H.M.;ALAM, Mohammad Jahangir;BISWAS, Al Amin;ISLAM, Mohammad Nazrul
    • The Journal of Asian Finance, Economics and Business
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    • v.9 no.4
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    • pp.29-38
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    • 2022
  • The enormous sway of COVID-19 on the international financial market has been felt across the globe. The financial markets of Bangladesh have also been similarly affected by the global epidemic and experienced a significant increase in volatility. To scrutinise the connection between COVID-19 and the Dhaka Stock Exchange (DSE) indices' return and instability, this study uses data of the DSE from February 2014 to September 2021. A comparative examination of the return and instability of the stock indices of the DSE has also been done considering the outbreak of the current COVID-19 situation. After using the GJR-GARCH (1,1) model, this review uncovers that the outbreak of COVID-19 has a statistically positive noteworthy association with the DSE stock indices' instability, which increases the market's volatility. Traders' fear and the rising frequency of COVID-19 reported patients could cause this. Besides, according to this study, COVID-19 shows a substantial positive linkage with stock market returns that increases the market's return. An appealing valuation, lower interest rates in the banking channel, economic rebound following the closure to prevent coronavirus transmission, improved remittance inflows, and a return of export revenues could all have contributed to this outcome. In addition, the findings also reveal that all market indices are in a mean-reverting phase.

A Study on the Gamification of SNS Challenge Contents (SNS 챌린지 콘텐츠의 게이미피케이션 연구)

  • Oh, Yoon-Ji;Lee, Jin
    • The Journal of the Korea Contents Association
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    • v.22 no.1
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    • pp.1-9
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    • 2022
  • The purpose of this study is to comprehensively consider the challenge contents enjoyed based on SNS through the concept of Gamification and MDA framework. Regardless of the top-down and bottom-up divisions, in common, the participants show an active figure leading the creation and enjoyment of contents. As a result of analyzing the challenge contents using the MDA framework, the mechanics of 'relative level', 'challenge with expressive purpose', and 'Paidia rules' were found. This leads to the dynamics of participants who express an inner sense of achievement such as 'selection and competition for better expression' and 'selflessness and superiority', creating an environment where they can continuously participate in the challenge contents. Lastly, looking at the aesthetics of the challenge contents, it can be seen that participants are actively forming a play culture that leads the creation and enjoyment of contents. This phenomenon has resulted in breaking down the hegemony of content creation and distribution, which was the responsibility of society in the field of information transmission and commercial advertising.

Study of the mechanical properties and effects of particles for oxide dispersion strengthened Zircaloy-4 via a 3D representative volume element model

  • Kim, Dong-Hyun;Hong, Jong-Dae;Kim, Hyochan;Kim, Jaeyong;Kim, Hak-Sung
    • Nuclear Engineering and Technology
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    • v.54 no.5
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    • pp.1549-1559
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    • 2022
  • As an accident tolerant fuel (ATF) concept, oxide dispersion strengthened Zircaloy-4 (ODS Zry-4) cladding has been developed to enhance the mechanical properties of cladding using laser processing technology. In this study, a simulation technique was established to investigate the mechanical properties and effects of Y2O3 particles for the ODS Zry-4. A 3D representative volume element (RVE) model was developed considering the parameters of the size, shape, distribution and volume fraction (VF) of the Y2O3 particles. From the 3D RVE model, the Young's modulus, coefficient of thermal expansion (CTE) and creep strain rate of the ODS Zry-4 were effectively calculated. It was observed that the VF of Y2O3 particles had a significant effect on the aforementioned mechanical properties. In addition, the predicted properties of ODS Zry-4 were applied to a simulation model to investigate cladding deformation under a transient condition. The ODS Zry-4 cladding showed better performance, such as a delay in large deformation compared to Zry-4 cladding, which was also found experimentally. Accordingly, it is expected that the simulation approach developed here can be efficiently employed to predict more properties and to provide useful information with which to improve ODS Zry-4.

The Impact of Country of Origin on Consumption Intention: A Case Study of COVID-19 Vaccines in Vietnam

  • VO, Minh Sang;TRAN, Ngoc Phu;NGUYEN, Thi Kieu Thu;HUYNH, Thi Cam Tien;NGUYEN, Thi Kim Loi;THACH, Le Phuong Nghi;THAI, Gia Nhu;TRAN, Thi Thanh Sang
    • The Journal of Asian Finance, Economics and Business
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    • v.9 no.4
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    • pp.121-129
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    • 2022
  • This study intends to analyze the impact of the country of origin on the intention to ingest COVID-19 vaccinations by measuring Vietnamese people's perceptions of India in the manufacture of COVID-19 vaccines. The research is done using a quantitative method, and primary data was obtained using a conventional manner based on the willingness of the research respondents, who are Vietnamese persons aged 18 and up, to contribute information. The findings revealed that perceived brand association and perceived brand quality directly positively impact the COVID-19 vaccine's consumption intention and willingness. Meanwhile, while the perceived country image component has no direct effect on consumption intention, it does have a positive indirect effect on consumption intention through perceived brand linkage and perceived brand quality. The findings also emphasize the importance and significance of a country's image in brand association and quality perception. The study's findings imply that to increase consumers' willingness to buy India's COVID-19 vaccination, the country should develop communication initiatives to improve consumer perceptions of the country's image, the perceived value of the brand association, and brand quality.

Preliminary study of passive acoustic monitoring of finless porpoises Neophocaena asiaeorientalis around the Southwest offshore wind farm in Korea (서남해 해상풍력 실증단지 주변에서의 수동 음향 관측을 이용한 상괭이 모니터링 가능성 연구)

  • Yoon, Young Geul;Yang, Wonjun;Choi, Jee Woong
    • The Journal of the Acoustical Society of Korea
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    • v.40 no.6
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    • pp.537-545
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    • 2021
  • Due to the accelerated development and transformation of coastal waters by humans, damage to marine mammals is a concern. To understand how coastal development may affect marine mammals, it is essential to determine their distribution characteristics. In this study, the appearance of finless porpoises was confirmed by passive acoustic monitoring around the Southwest offshore wind farm in July, 2020. Although there were no visual observation results of finless porpoises in the research area, the clicks measured in the offshore wind farm were verified by comparing with acoustic characteristics of the clicks measured in the area with a high detection rate. During the experimental period, clicks of finless porpoises were recorded for ten consecutive days, and Clicks per Porpoise Positive Minute (CPPM) was 40.7 clicks min-1, Porpoise Positive Minutes (PPM) was 9.7 %, Encounter duration and waiting time were 18.2 min and 94.9 min respectively. This study provides information on the appearance of them in the Southwest offshore wind farm and this result may help to monitor the impact of marine mammals from wind farm operation.