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Genotype Distribution and Behavioral Risk Factor Analysis of Human Papillomavirus Infection in Uyghur Women

  • Sui, Shuang;Jiao, Zhen;Niyazi, Mayinuer;Sulaiya, Sulaiya;Lu, Ping;Qiao, You-Lin
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.10
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    • pp.5861-5865
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    • 2013
  • We investigated the distribution of HPV genotypes in Uyghur women in Xinjiang region of China, and behavioral factors which could predispose them to HPV infection. In this cross-sectional study, women aged 15-59 years were recruited by cluster sampling method in Yutian region in 2009. Liquid-based cytology samples were analyzed centrally for HPV genotype with a linear array detector. Univariate and multivariate logistic regression analyses were performed to identify behavioral risk factors for HPV infection. A total of 883 Uyghur women were recruited successfully. The prevalence of high-risk HPV and low-risk HPV were 7.25% and 1.58%, respectively; the most common HPVs were HPV16, 51, 31, 39 and 58. We found that age of first sexual intercourse was a strong predictor for HPV infection (odds ratio of 4.01 for ${\leq}15$ years versus ${\geq}25$). Having sexual partners ${\geq}3$ was the second predictor (OR 3.69, 95% CI 2.24-7.16). Cleaning the vagina after sex showed an increased risk of HPV infection (OR 2.72; 95% CI 1.98-5.13); Using the condom showed protective factors for HPV infection (OR 0.36; 95%CI0.12-0.53). HPV16, 51, 31, 39 and 58 were the priority types; the age of first sexual intercourse was identified as a major risk factor for HPV infection. Other notable risks were number of sexual partners and cleaning the vagina after sex. Changing these behavioral risk factors could help to reduce the occurrence of cervical cancer in this population.

Practical Implementation of Patient-Specific Quality Assurance for Small and Multiple Brain Tumors in CyberKnife with Fixed Collimators

  • Lee, Eungman;Park, Kwangwoo;Kim, Jin Sung;Kim, Yong Bae;Lee, Ho
    • Progress in Medical Physics
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    • v.29 no.2
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    • pp.53-58
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    • 2018
  • This paper evaluates patient-specific quality assurance (PSQA) in the treatment of small and multiple tumors by the CyberKnife system with fixed collimators, using an ion chamber and EBT3 films. We selected 49 patients with single or multiple brain tumors, and the treatment plans include one to four targets with total volumes ranging from 0.12 cc to 3.74 cc. All PSQA deliveries were performed with a stereotactic dose verification phantom. The A16 microchamber (Standard Imaging, WI, USA) and Gafchromic EBT3 film (Ashland ISP Advanced Materials, NJ, USA) were inserted into the phantom to measure the point dose of the target and the dose distribution, respectively. The film was scanned 1 hr after irradiation by a film digitizer scanner and analyzed using RIT software (Radiological Imaging Technology, CO, USA). The acceptance criteria was <5% for the point dose measurement and >90% gamma passing rate using 3%/3 mm and relative dose difference, respectively. The point dose errors between the calculated and measured dose by the ion chamber were in the range of -17.5% to 8.03%. The mean point dose differences for 5 mm, 7.5 mm, and 10 mm fixed cone size was -11.1%, -4.1%, and -1.5%, respectively. The mean gamma passing rates for all cases was 96.1%. Although the maximum dose distribution of multiple targets was not shown in the film, gamma distribution showed that dose verification for multiple tumors can be performed. The use of the microchamber and EBT3 film made it possible to verify the dosimetric and mechanical accuracy of small and multiple targets. In particular, the correction factors should be applied to small fixed collimators less than 10 mm.

Type Distribution of Lymphomas in Lebanon: Five-Year Single Institution Experience

  • Sader-Ghorra, Claude;Rassy, Marc;Naderi, Samah;Kourie, Hampig Raphael;Kattan, Joseph
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.14
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    • pp.5825-5828
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    • 2014
  • Background: Lymphomas represent the fifth most frequent cancer in Lebanon. However, little is known concerning epidemiologic characteristics and distribution of lymphoid neoplasms according to the 2008 WHO classification. Materials and Methods: We conducted a retrospective study of lymphoma cases diagnosed from 2008 till 2012 at $H\hat{o}tel$-Dieu de France University Hospital. Results: A total of 502 new cases of lymphoma were diagnosed at our institution during a five year period: 119 cases (24%) were Hodgkin lymphomas (HL) and 383 cases (76%) were non-Hodgkin lymphomas (NHL). HLs were equally distributed in both sexes with a mean age at diagnosis of 30 years. Among NHL, 87% (332 cases) were B cell lymphomas, 9% (34 cases) were T cell lymphomas and 4%(17 cases) were classified as precursor lymphoid neoplasms. Among B cell lymphomas, 44% (147 cases) were diffuse large B cell lymphomas (DLBCL), 20% (65 cases) follicular lymphomas and 8% (27 cases) mantle cell lymphomas. DLBCL were equally distributed in both sexes with a mean age of 58 years. Follicular lymphomas were characterized by a male predominance (57%) and a mean age of 60 years. Mantle cell lymphomas showed a pronounced male predominance (85%) with a mean age of 60 years in men and 70 years in women. Some 72% of patients having T cell lymphomas were men, with a mean age of 57 years in men and 45 years in women, while 65% of patients having precursor lymphoid neoplasms were women with a mean age of 22 years in women and 30 years in men. Conclusions: The lymphoma subtype distribution in Lebanon is unique when compared to other countries from around the world. In fact, Hodgkin and follicular lymphomas are more frequent than in most Far Eastern, European and American countries, while T-cell lymphomas and DLBCL are less frequent.

Histopathological Diversity in Parotidectomy Materials in Turkish Population: Clinicopathologic Analysis and Demographic Features of 136 Cases in a Tertiary Care Hospital

  • Altinay, Serdar;Taskın, Umit;Sar, Mehmet;Aydin, Salih;Oktay, Mehmet Faruk
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.14
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    • pp.5701-5707
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    • 2014
  • Background: Salivary gland tumours, which account for approximately 3% of head-neck cancers, are a heterogeneous group and thus it is difficult to identify their epidemiological characteristics. The aim of this study is to determine demographic features and histopathologic distribution of parotid neoplasms in a large sample from Turkey. Materials and Methods: This study was conducted retrospectively on 136 parotidectomy materials from operations between May 2009-May 2013. Age, gender, tumor diameter, histopathological diagnosis and surgical margin status were recorded. Results: The benign cases were 112 (82.4%), while the malignancies were 24 (17.6%). The accuracy rate of FNAC was 91%. There were 46 (33.8%) male and 90 (66.2%) female patients. Female/male ratio (M/F=0.5) was two, the Warthin (WT) tumor being more apparent in males (p<0.05). Pleomorphic adenoma (PA) was detected most frequently among benign pathologies at 61.6% (69/112), while the Warthin Tumor (WT) was detected as the second most frequent tumor at 20.5% (23/112). Mucoepidermoid carcinoma (MEC) and carcinoma ex pleomorphic adenoma (Ca ex PA) were detected at equal frequency at 20.8% (5/24) among malign tumors. These were followed by acinic cell carcinoma at 16.7% (4/24). While the surgical margin was positive in ten patients with malignant tumors (41.7%), all of the benign tumors were negative (p<0.01). No significant difference was detected in the age-gender of patients, tumor size and distribution of sites among benign and malignant groups (p>0.05). Conclusions: Pleomorphic adenoma is the most frequently reported benign tumor almost in all global literature. Yet, the distribution of malignant tumors displays geographical differences. Based on these data, we believe that our findings will provide a significant contribution to future epidemiological studies. We think that it will be beneficial to generate awareness on parotid tumors and ensure a fight against smoking as with all head-neck cancers.

Sympatric Distribution of Three Human Taenia Tapeworms Collected between 1935 and 2005 in Korea

  • Jeon, Hyeong-Kyu;Kim, Kyu-Heon;Chai, Jong-Yil;Yang, Hyun-Jong;Rim, Han-Jong;Eom, Kee-Seon S.
    • Parasites, Hosts and Diseases
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    • v.46 no.4
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    • pp.235-241
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    • 2008
  • Taeniasis has been known as one of the prevalent parasitic infections in Korea. Until recently, Taenia saginata had long been considered a dominant, and widely distributed species but epidemiological profiles of human Taenia species in Korea still remain unclear. In order to better understand distribution patterns of human Taenia tapeworms in Korea, partial nucleotide sequences of mitochondrial cox1 and ITS2 (internal transcribed spacer 2) were determined, along with morphological examinations, on 68 Taenia specimens obtained from university museum collections deposited since 1935. Genomic DNA was extracted from formalin-preserved specimens. Phylogenetic relationships among the genotypes (cox1 haplotype) detected in this study were inferred using the neighbor-joining method as a tree building method. Morphological and genetic analyses identified 3 specimens as T. solium, 51 specimens as T. asiatica, and 14 specimens as T. saginata. Our results indicate that all 3 Taenia tapeworms are sympatrically distributed in Korea with T. asiatica dominating over T. saginata and T. solium.

Assessment of Flood Probability Based on Temporal Distribution of Forecasted-Rainfall in Cheongmicheon Watershed (예보강우의 시간분포에 따른 청미천 유역의 홍수 확률 평가)

  • Lee, Hyunji;Jun, Sang Min;Hwang, Soon Ho;Choi, Soon-Kun;Park, Jihoon;Kang, Moon Seong
    • Journal of The Korean Society of Agricultural Engineers
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    • v.62 no.1
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    • pp.17-27
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    • 2020
  • The objective of this study was to assess the flood probability based on temporal distribution of forecasted-rainfall in Cheongmicheon watershed. In this study, 6-hr rainfalls were disaggregated into hourly rainfall using the Multiplicative Random Cascade (MRC) model, which is a stochastic rainfall time disaggregation model and it was repeated 100 times to make 100 rainfalls for each storm event. The watershed runoff was estimated using the Clark unit hydrograph method with disaggregated rainfall and watershed characteristics. Using the peak discharges of the simulated hydrographs, the probability distribution was determined and parameters were estimated. Using the parameters, the probability density function is shown and the flood probability is calculated by comparing with the design flood of Cheongmicheon watershed. The flood probability results differed for various values of rainfall and rainfall duration. In addition, the flood probability calculated in this study was compared with the actual flood damage in Cheongmicheon watershed (R2 = 0.7). Further, this study results could be used for flood forecasting.

Descriptive Study of Occupational Accidents and their Causes among Electricity Distribution Company Workers at an Eight-year Period in Iran

  • Rahmani, Abdolrasoul;Khadem, Monireh;Madreseh, Elham;Aghaei, Habib-Allah;Raei, Mehdi;Karchani, Mohsen
    • Safety and Health at Work
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    • v.4 no.3
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    • pp.160-165
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    • 2013
  • Background: Occupational accidents are unplanned events that cause damage. The socio-economic impacts and human costs of accidents are tremendous around the world. Many fatalities happen every year in workplaces such as electricity distribution companies. Some electrical injuries are electrocution, electric shock, and burns. This study was conducted in an electricity distribution company (with rotational 12-hour shift work) in Iran during an 8-year period to survey descriptive factors of injuries. Methods: Variables collected included accident time, age of injured worker, employment type, work experience, injury cause, educational background, and other information about accidents. Results: Results indicated that most of the accidents occurred in summer, and 51.3% were during shift work. Worker negligence (malpractice) was the cause of 75% of deaths. Type of employment had a significant relationship with type of injuries (p < 0.05). Most injuries were electrical burns. Conclusion: High rate of accidents in summer may be due to the warm weather or insufficient professional skills in seasonal workers. Shift workers are at risk of sleep complaints leading to a high rate of work injuries. Acquiring knowledge about safety was related to job experiences. Temporary workers have no chance to work all year like permanent workers, therefore impressive experiences may be less in them. Because the lack of protective equipment and negligence are main causes of accidents, periodical inspections in workshops are necessary.

Characteristics of Weather and Climate over the Okhotsk Sea

  • KIM Young Seup;HAN Young Ho;CHEONG Hyeong Bin;DASHKO Nina A.;PESTEREVA Nina M.;VARLAMOV Sergey M.
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.30 no.6
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    • pp.974-983
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    • 1997
  • The Okhotsk Sea is unique natural object with climatic peculiarities. The climate of the Okhotsk Sea results from the general distribution of solar radiation during a year, and the characteristics of the atmospheric circulation that varies through a year: In cold half year the main pressure formations are Siberian high and Aleutian low. Asian low centered on Afghanistan dominates over the Asian continent in summer. The North-Pacific sea surface is under effect of permanent North Pacific high. The changes in their position from year to year are very significant. The anticyclonic activity over the Far Eastern Seas is one of the main factors for the formation of weather anomalies over the adjacent territories. The analysis of summer weather characteristics over the coast of Okhotsk and East Sea using the data obtained from Hydrometeorological stations during $1949\~1990$ showed that, to a great extent, distribution of the air temperature depends on thermal state of the Okhotsk Sea and atmospheric circulation over it. We show some relations between weather characteristics and the intensity of atmospheric action center for the North Pacific high in summer when its ridge propagates to Okhotsk Sea. Correlation coefficients between air pressure over the Okhotsk Sea and air temperature for the coastal areas reach up to 0.7. Analysis of the spatial-temporal distribution of main meteorological values over the Okhotsk Sea such as air pressure, and air temperature are also performed.

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Improvement in the Simulation of Sea Surface Wind over the Complex Coastal Area Using WRF Model (WRF 모형을 통한 복잡 연안지역에서의 해상풍 모의 개선)

  • Kim, Yoo-Keun;Jeong, Ju-Hee;Bae, Joo-Hyun;Oh, In-Bo;Kweon, Ji-Hye;Seo, Jang-Won
    • Journal of Korean Society for Atmospheric Environment
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    • v.22 no.3
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    • pp.309-323
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    • 2006
  • We focus on the improvement in the simulation of sea surface wind over complex coastal area located in the southeastern Korea. In this study, it was carried out sensitivity experiment based on PBL schemes and dynamic frame of MM5 and WRF. Two widely used PBL parameterization schemes were chosen : Medium-Range Forecast (MRF) and Mellor-Yamada-Janjic (MYJ). Thereafter, two cases of sea fog days with weak wind speed and typhoon days with strong wind speed were simulated and analyzed. The result of experiments indicated that wind fold of WRF model was shown more similar distribution with observational data, compared with that of MM5. Simulation of sea surface wind during sea fog days with weak wind speed and typhoon days with strong wind speed were shown similar horizontal distribution with observational data using MYJ and MRF PBL schemes of WRF model, respectively. Horizontal distribution of sea surface wind was more sensitive according to dynamic frame and PBL Schemes of model during sea fog days and typhoon days, respectively.

A STATISTICAL STUDY ON WORKING LENGTH OF UPPER AND LOWER ANTERIOR TEETH IN ENDODONTIC TREATMENT (상·하악 전치부의 근관치료에 사용되는 시술길이(Working Length)에 관한 통계학적 연구)

  • Choe, Dong-Hun;Park, Dong-Soo;Lee, Chan-Young;Lee, Chung-Suck
    • Restorative Dentistry and Endodontics
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    • v.10 no.1
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    • pp.169-175
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    • 1984
  • This study was undertaken to obtain the average canal length of upper & lower anterior teeth which was important in canal length measuring procedure of endodontic treatment. It was based upon 827 out-patients who had endodontic treatment on their upper & lower anterior teeth at the Department of Operative Dentistry, Dental Infirmary, Yonsei Medical Center from February, 1978 to June, 1984. The 1249 teeth of these patients were devided into sex and age groups. The root canal length of these teeth were measured. The following results were obtained; 1. The mean root canal length of upper & lower anterior teeth were as follows; Upper central incisors : 21.8mm Upper lateral incisors : 21.0mm Upper canines : 24.1mm Lower central incisors : 18.6mm Lower lateral incisors : 19.9mm Lower canines : 22.6mm 2. There was no significant difference in root canal length between sex. (P > 0.05) 3. There was no significant difference in root canal length between age groups. (p > 0.05) 4. The distribution of upper central incisors showed the highest distribution followed by upper lateral incisors and lower central incisors between 10 to 40 year old age groups, and there was no signigicant difference in the rest of the age groups. There was no significant difference in sex distribution, which was 49.5% for males and 50.4% for females. The number of the upper anterior teeth was 74.3% of all the specimens and the lower anterior 25.7%, and 40.6% of all the specimens were upper central incisors.

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