• 제목/요약/키워드: Distributed L-C

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EFFECTS OF SPIRAMINE ALKALOIDS ON THE PLATELET AGGREGATION

  • jiang, Hao-Xiao
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1998.11a
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    • pp.66-71
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    • 1998
  • Spiraea japonica L. F., a plant species belongs to the Spiraea genus of Rosaceae family, has seven varieties. There are all varieties distributed in Yunnan province of China, and S. japonica var. acuminata and S. japonica var. fortunei were used as the folk medicines to treat malaria and inflammation etc.. Since 1960s, Japanese and Russian scholars obtained C$\_$20/-diterpenoid alkaloids from S. japonica L.F., also Chinese scholars got a series of Hetisine-type C$\_$20/-diterpenoid alkaloids from S. japonica var. fortunei in 1985. Since then, we started the chemical and pharmaceutical studies of this complex. Here we wish to report the bioactive effects of spiramine alkaloids and their derivatives on the platelet aggregation induced by AA, PAF, or ADP.

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Low Noise Characteristics of SRM Drive with Hybrid Excitation (하이브리드 여자방식 SRM의 저소음 구동특성)

  • Kim, C.S.;Oh, S.G.;Ahn, J.W.;Kim, C.W.
    • Proceedings of the KIEE Conference
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    • 2001.04a
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    • pp.53-56
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    • 2001
  • The simple construction and low cost, fault tolerant power electronic drive has made the switched reluctance drive a strong contender for many applications. But the switched reluctance drive does exhibit higher levels of vibration and acoustic noise than most competing drives. The main source of vibration in the switched reluctance drive is generated by rapid change of radial force when phase current is extinguished by commutation action. In this paper, a hybrid excitation method is proposed to reduce vibration and acoustic noise of the switched reluctance drive. The hybrid excitation has 2-phase excitation by long dwell angle as well as conventional 1-phase excitation. The vibration and acoustic noise are reduced because the scheme reduces abrupt change of excitation level by distributed and balanced excitation.

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Karyotype Analysis of Lilium cernum Komrov by Means of C-banding Method (Giemsa 분염법에 의한 솔나리의 핵형 분석)

  • 손진호
    • Journal of Plant Biology
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    • v.21 no.1_4
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    • pp.29-32
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    • 1978
  • The karyotype of Lilium cernum has been analysed by means of C-banding technique. Most of clones observed were 2n=24 chromosomes which consist of two pairs of submetacentric and ten pairs of subtelocentric chromosomes, among which two pairs of chromosomes(B and E) showed secondary constriction in the short arm. In addition to these chromosomes a small supernumerary telocentric chromosome was seen in the eight clones. Sixtyeight bands were observed in the twentytwo chromosomes of complement and one band in the supernumerary chromosome. A pair of chromosome (L) did not show any band. The bnads on the chromosome. A pair of chromosome (L) did not show any band. The bands on the chromosomes were distributed in the centromere, secondary constriction and intercalary regions of arms. Of the twelve pairs of chromosomes ten pairs showed symmetric banding patterns in each, but two pairs (I and K) showed asymmetric banding patterns.

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Development of Mathematical Model for the Hydrolysis Fish Oil (물고기 기름의 가수분해에 대한 수학적 모형개발)

  • Kim Won-Ho;Lee Yong-Hoon;Park Ji-Suk;Hur Byung-Ki
    • KSBB Journal
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    • v.20 no.2 s.91
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    • pp.106-111
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    • 2005
  • The functional relationship between the number of mole of an i-fatty acid (Si) included in fish oil and the hydrolysis time(t) was expressed as a mathematical model, $S_i=-{\alpha_i}1n(t)+\beta_i$. The average errors of calculated values on the basis of the measured values were distributed in the range of less than $5\%$ for all the 15 fatty aids composing of fish oil. The equation of hydrolysis rate of each fatty acid was deduced as $v_i={\gamma_i}exp(\frac{S_i}{\alpha_i})$ from the above-mentioned $S_i=-{\alpha_i}ln(t)+{\beta_i}$. Therefore the hydrolysis yields of fatty acids were analyzed using the equation of $S_i\;Vs.\;t.$. The 15 fatty acids were categorized into 4groups from the view point of hydrolysis yield. The hydrolysis yields of the first group, including C14:0, C16:0, C16:1, C18:0, C18:1 (n-7) and 1l8:1 (n-9), were higher than $70\%$ at 48 hr of hydrolysis. Those of the second group, C20:1, C22:1, C18:3, C20:4 and C20:5, were distributed from $40\%,\;to\;60\%$, and third group were around $30\%$. The final group containing only C22:6 was very hard to be hydrolyzed and the yield was less than $20\%$ at the same time.

Analysis on the Correlation Between Vegetation Structure and Environment Factors of the Geumosanseong-inside in Geumosan Provincial Park, in Korea (금오산도립공원의 금오산성 식생구조와 환경요인의 상관관계 분석)

  • Kim, Hyoun-Sook;Park, Gwan-Soo;Lee, Sang-Myong;Lee, Joong-Ku
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.23 no.2
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    • pp.49-67
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    • 2020
  • This study was conducted to compare and analyze forest vegetation distributed in Geumosanseong-inside in Geumosan Provincial Park from 2017.10 to 2019.6. The vegetation structure was classified by the phytosociological method and TWINSPAN and the correlation between the community structure and the environmental factors was analyzed using DCCA ordination analydsis. The vegetation structures are Quercus mongolica, Fraxinus mandshurica, Q. acutissima, Larix leptolepis, Prunus padus and Morus alba community by the phytosociological method and 16 communities under TWINSPAN. The importance value of Q. mongolica(64.5) was the highest, and followed by F. mandshurica, L. leptolepis, Acer pseudosieboldianum, M. alba, P. padus, Q. acutissima, Sorbus alnifolia, P. serrulata var. pubescens, F. sieboldiana, Rhododendron schlippenbachii and Castanea crenata which is consistent with species having the dominance status by analysis of the vegetation structure. As the results of DBH analysis for taxon with high importance values, Q. mongolica and M. alba represented normal distribution, and thus, the dominance status of these species is likely to continue. L. leptolepis will maintain the dominance status due to high density of large individuals as compared with species above medium size. However, it will decrease because of high mortality after increase in age class. F. mandshurica and P. padus continue to show dominance status due to high density of young individuals as compared with species above medium size. Q. acutissima have high density of individuals above intermediate size and low density of young individuals, and thus, will maintain the dominance status. A. pseudosieboldianum, F. sieboldiana and R.schlippenbachii which are arborescent will present continuously high dominance status because of high density of young individuals. Soil analysis shows that whereas pH, Ca2+ and Mg2+ in the research area were lower than the average values of overall forest soil and O.M, T-N, C.E.C and P2O5 were higher. We expected that these results were due to agricultures until 50 years ago in Geumosanseong-inside. As a result of DCCA ordination analysis using eleven environmental factors and communities classified by the phytosociological method analysis showed that Q. mongolica was distributed in the environment with higher elevation and O.M and steep slope, and lower P2O5, Mg2+ and Ca2+. In contrast to F. mandshurica, Q. acutissima was distributed in higher K+ and lower pH. L. leptolepsis was distributed in various environment.

The Effect of Injection Timing and Cavity Geometry on Fuel Mixture Formation in a Central Injected DI Gasoline Engine (중앙 분사방식의 직분식 가솔린 기관에서 연료 혼합기 형성에 미치는 분사시기와 캐비티 형상의 영향)

  • 김태안;강정중;김덕줄
    • Transactions of the Korean Society of Automotive Engineers
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    • v.12 no.2
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    • pp.32-38
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    • 2004
  • This study was performed to investigate the behavior of liquid and vapor phase of fuel mixtures with different piston cavity diameters in a optically accessible engine. The conventional engine was modified as Central Injected DI gasoline engine with swirl motion. Two dimensional spray fluorescence images of liquid and vapor phase were acquired to analyze spray behavior and fuel distribution inside of cylinder using exciplex fluorescence method. Piston cavity geometries were set by Type S, M and L. The results obtained are as follows. In the spray formation after SOI, the cone angle and width of the spray were decreased at late injection timing. With a fuel injection timing of BTDC $180^{\circ}C$, fuel was not greatly affected in a piston cavity but generally distributed as homogeneous mixture in the cylinder. With a fuel injection timings of BTDC $90{\circ}C$ and $60^{\circ}C$, fuel mixture was widely distributed in near the cavity center. As a injection timing was late in the compression stroke, residual width of fuel mixture was narrow in proportion to piston cavity.

Biomass of Shellfish in the Saemangeum Tidal Flat on the West Coast of Korea (새만금 갯벌의 패류 생물량)

  • KIM Jong-Sheek;HWANG Sun-Do
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.36 no.6
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    • pp.757-761
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    • 2003
  • Spatial distribution and biomass of commercial shellfish were investigated in the Saemangeum tidal flat on the west coast of Korea during August 1999. Thirteen species of shellifsh were collected. Major dominant species of the study area were Umbonium thomasi with a density of $6.7\;ind.{\cdot}m^{-2}\;(38.2\%)$, Mactra veneriformis with $6.6\;ind.{\cdot}m^{-2}\;(37.4\%)$ and Reticunassa festiva with $1.3\;ind.{\cdot}m^{-2}\;(7.2\%)$. Commercially important species such as M. veneriformis ($90.7\;ind.{\cdot}m^{-2}\;69.3\%$), M. lusoria ($15.6\;ind.{\cdot}m^{-2}\;11.9\%)$), C. sinensis ($8.7\;ind.{\cdot}m^{-2}\;6.7\%)$) were dominant in total weight. Most of the shellfish were distributed between the mid-littoral and sub-littoral zones, but C. sinensis and L. flexuosa were distributed mainly in the polluted areas of the supra-littoral zone. The spatial distribution pattern of each shellifsh species generally resembles the Mangyeong and Dongjin estuary. Biomass of commercially important species, M. veneriformis, M. lusoria, C. sinensis and Ruditapes philippinarum in the tidal flat (ca. 850 ha) was estimated to be 774, 135, 67 and 10 tons, respectively.

A Study on the Eutrophication in Artificial Lakes in Chonnam Area (全南地方의 一部 人工湖水의 富營養化에 관한 조사연구)

  • Kim, Seung Ho
    • Journal of Environmental Health Sciences
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    • v.11 no.1
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    • pp.15-28
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    • 1985
  • In order to analyze the water quality in artificial lakes in Chonnam area, a chemical and biological examination of Dongbock Lake and Changsung Lake was conducted from September to December 1983 and May 1984. A summary of the surveyed results is as follows 1. In Dongbock Lake, pH ranged from 7.2-8.1, D.O.: 8.2-12.6mg/l, B.O.D.: 4.4-22.1 mg/l, C.O.D.: 1.0-3.4rag/l, Cl$^-$: 5.9-11.9mg/l, Total-P: 0.001-0.071 mg/l, and Total -N: 0.016-0.697 mg/l, respectively. 2. In Changsung Lake, pH ranged from 7.2-8.1, D.O.: 8.1-9.8mg/l, B.O.D.: 0.9-2.9mg/l, C.O.D.: 1.9-3.4mg/l. Total- P: 0.006-0.016mg/l and Total -N:0.006-0.033mg/l, respectively. 3. The Phytoplankton identified in this investigation were distributed in a total of 46 genera and 76 spedes in Dongbock Lake 37 genera and 45 species in Changsung Lake. 4. In Dongbock Lake, it was found that the dominant algae were Melosira sp., Microcystis sp. and Synedra sp. in September Melosira sp. and Microcytis sp. in October, but Cymbella sp., Naviculla sp. and Nitzschis sp. were also observed in OctoberAsterionella sp., Melosira sp. and Microsystis sp. in November and Melosira sp., Asterionella sp sp. and Synedra sp. in December 1983. 5. In Changsung Lake, it was found that the dominant algae were Melosira sp., Lyngrbya sp. and Microcystis in September Melosira sp. and Synedra sp. in October and November and Melosira sp., Lyngbya sp. and Asterionella sp. in December 1983. The dominant algae were Melosira sp., Lyngbya sp. and Euglena sp. in May 1984. 6. It was found that the dominant algae in both Dongbock and Changsung Lakes were Microcystis sp., Melosira sp. and Asterionella sp.. Which are strongly related with water-bloom. Therefore, it could be suggested that the eutrophication phenomena is going to occur very easily in Dongbock Lake and possibly in Changsung Lake.

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Anti-obesity Effect of Yogurt Fermented by Lactobacillus plantarum Q180 in Diet-induced Obese Rats

  • Park, Sun-Young;Seong, Ki-Seung;Lim, Sang-Dong
    • Food Science of Animal Resources
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    • v.36 no.1
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    • pp.77-83
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    • 2016
  • This study aimed to investigate the anti-obesity effects of yogurt fermented by Lactobacillus plantarum Q180 in diet-induced obese rats. To examine the effects, male Sprague-Dawley rats were fed on six different diets, as follows: Group A was fed an ND and orally administrated saline solution; Group B, an HFD and orally administrated saline solution; Group C, an HFD and orally administrated yogurt fermented by ABT-3 and L. plantarum Q180; Group D, an HFD and orally administrated yogurt with added Garcinia cambogia extract, fermented by ABT-3 and L. plantarum Q180; Group E, an HFD and orally administrated yogurt fermented by L. plantarum Q180; and Group F, an HFD and orally administrated yogurt with added Garcinia cambogia extract, fermented by L. plantarum Q180 for eight weeks. After eight weeks, the rate of increase in bodyweight was 5.14%, 6.5%, 3.35% and 10.81% lower in groups C, D, E and F, respectively, compared with group B; the epididymal fat weight of groups E and F was significantly lower than that of group B; and the level of triglyceride and leptin was significantly reduced in groups C, D, E and F compared to group B. In addition, the level of AST was reduced in group C compared to the other groups. To examine the effects of yogurt on the reduction of adipocyte size, the adipocyte sizes were measured. The number of large-size adipose tissue was less distributed in groups A, C, D, E and F than in group B.

Newly Designed Six-membered Azasugar-Containing Phosphorothioate Oligonucleotide as a Potent AIDS Therapeutic Drug

  • Bae, Yong-Soo
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.155-160
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    • 2002
  • A series of modified oligonucleotides containing a phosphorothioate (P=S) backbone and a six-membered azasugar (6-AZS) as a sugar substitute in a nucleotide were synthesized and tested for their ability to inhibit the human immunodeficiency virus type I(HIV-l) in vitro without the aid of any transfecting agents. While P=S oligonucleotides with natural nucleotides had little anti-HIV-l activity, the six-membered azasugar nucleotide (6-AZN)-containing P=S oligonucleotides (AZPSONs) potently inhibited the HIV-l/SHIV replication and syncytium formation (ECso = 0.02-0.2 /lM) without cytotoxicity up to 100 /lM. DBM-2198, the most effective in anti-HIV-l activity among the AZPSONs, consists of random sequence and five 6¬AZNs evenly distributed in 18 nucleotides. DBM-2198 showed strong antiviral activity against, not only laboratory strains, but also primary isolates and even drug-resistant strains of HIV-I. DBM-2198 was much more effective than ddI or ddC in its anti-HIV-l activity in vitro. Particularly noteworthy is that the anti-HIV-l activity of DBM-2198 was better than that of AZT with respect to its long-lasting efficacy after a single treatment. Nevertheless, the antiviral activity of the AZPSONs was very specific to HIV-I. Poliovirus, or even simian immunodeficiency virus (SIV), was not inhibited by the AZPSONs. Taken together, our results strongly suggest that AZPSON can be used as a safe and effective AIDS-therapeutic drug against a broad spectrum of HIV -1 strains.

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