• 핵의학기술
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• 제13권3호
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• pp.181-184
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• 2009

목적 : 자동 분주기 (TECAN)의 fixed tip 사용 시 충분한 세척에도 불구하고 고농도 검체 뒤에 연이은 검체가 영향을 받는 carryover 현상이 발생되는 경우가 있다. 이는 검사결과가 위 양성으로 나타날 수 있는 위험성이 있으므로 이상유무 판단을 위해 잦은 재검을 실시해야 하는 번거로움이 있다. 따라서 본 연구는 경제성이 높은 fixed tip을 사용하면서 carryover를 방지할 수 있는 방법을 개선하고자 한다. 실험재료 및 방법 : 자동분주기(Tecan)를 이용하여 HBs Ag, HBs Ab, HBc Ab(IgG) 검사를 대상으로 실행하였으며, fixed tip 방식의 분주시스템으로 일반 환자의 검체 분주 후에 생리식염수를 분주 할 수 있도록 배치하였다. 세척 단계는 0.25mol/L NaOH용액을 이용하였으며, 생리식염수의 검사결과 cpm을 측정하여 carryover의 발생 유무를 확인하였다. 또한 3가지 검사를 0.25 mol/L NaOH 용액이 검사에 미치는 영향을 분석하였다. 결과 : 생리식염수 결과는 100% 음성결과를 보였으며, 0.25 mol/L NaOH를 세척액으로 사용한 fixed tip에서 검체분주 시 환자 혈청은 HBc Ab (IgG)검사에서 cut-off zone (cut-off${\pm}$10%)을 제외한 모든 결과에서 기존 외래보고 결과와 동일한 값을 얻었다. 결론 : 생리식염수 검사결과 100% 음성을 보인 것은 실험에서 사용한 세척액으로 fixed tip을 세척하는 방법이 carryover를 방지할 수 있고, 이로 인해 발생하는 위양성을 방지할 수 있었다. 또한, 환자 검체의 결과 값이 기존 보고 결과와 일치함으로 0.25 mol/L NaOH 용액이 간염 검사결과에 영향을 끼치지 않음을 확인하였다. 따라서 본 실험에서 실시한 방법이 disposable tip보다 상대적으로 경제적인 fixed tip을 사용하면서도 carryover가 없는 정확한 결과를 얻을 수 있는 효과적인 방안임을 알 수 있다.

• 자원환경지질
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• 제47권3호
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• pp.237-246
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• 2014

본 연구는 산업연관표의 투입산출표와 거시계량경제모형을 연계하여 산업부문에 발생한 충격의 효과가 거시변수에 미치는 효과를 예측할 수 있도록 모형화 하였으며, 모형을 통해 광산품 부문의 수입대체에 따른 경제적 효과를 추정하였다. 구축한 모형의 전반적인 개요는 거시계량경제모형을 구축하고 산업연관표를 통해 도출된 피용자보수를 국민계정상 가처분소득의 대리변수로 이용하여 두 분석틀을 연계하였다. 거시계량경제모형은 한국은행이 작성한 1997년 기준 모형을 근간으로 하여 최근의 한국은행 모형을 통해 수정 및 보완하여 2011년 기준의 연간 거시계량경제모형을 구축하였으며, 산업연관분석과 연계되는 가처분소득과 총취업자수 부분을 수정도입하였다. 산업연관표 부분은 2005년~2011년의 통합대분류 경상표 및 그 계수표를 이용하였다. 구축된 모형을 적용하여 광산품 중간투입 중 1%의 수입대체가 미치는 경제효과를 추정하였는데, 2011년 기준으로 GDP 0.00073% 증가, 경상수지 0.01040% 증가, 실업률 0.00233%p 감소의 효과가 나타났다. 본 연구는 거시변수를 이용하여 지출측면 중심으로 활용되던 거시계량경제모형에 산업연관표를 활용함으로써 산업 수준의 충격과 투입부문을 고려할 수 있도록 하였다는 점에 의의가 있다.

• 한국수정란이식학회지
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• 제15권3호
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• pp.295-302
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• 2000

The objective of this study was to compare different superovulation treatments using PMSG or PG600$^{ }$ and to determine the optimal time of oocyte recovery after hCG administration. A total of 90 prepubertal Yorkshire x Landrace gilts crossed with Duroc, 6~7 months old and 100~120 kg of body weight, were used. PMSG (1,500 IU/head) or 5~7.5 ml of PG600$^{ }$(400 IU of PMSG and 200 IU of hCG) were administrated subcutaneously, and then 1,000 IU of hCG were administered intramuscularly at 72 hours after PMSG or PG600$^{ }$ injection. At carious time of 44, 46, 48 and 50 hours after hCG injection, superovulated gilts were slaughtered in a local abattoir. Ovaries together with oviducts were excised from the body immediately after slaughtered and transported to laboratory in 39$^{\circ}C$ saline. Ovaries were examined fur the number of corpus hemorrhagicum and unovulated follicles present in the surface of ovary. The unovulated follicles were categorized into small (1~3 mm in diameter) and large (4~8 mm) groups according to their diameter. Oocytes were recovered by flushing both oviducts with micropipette tip (1~100 $\mu$l) attached to a 10-ml disposable syringe. The number of CH on ovary and recovered oocytes at 46, 48 and 50 hr after hCG injection in PG600$^{ }$ treated groups were significantly higher than the other group. Group of phCG 50 hr among PMSG treated groups had a greater number of CH and recovered oocytes(P<0.05). The number of CH on ovary and recovered oocytes at 50 hr after hCG injection in 1$\frac{1}{2}$ vial(7.5 ml) of PG600$^{ }$ treated groups was significantly higher than 1 vial(5 ml) of PG600$^{ }$ treated group(P<0.05). In conclusions, considering a number of corpus hemorrhagicum and recovered oocytes after superovulation in gilts, effective time of oocyte recovery by treatment with PMSG and hCG was post-hCG 50 hr and with PG600$^{ }$ plus hCG was post-hCG 46, 48 and 50 hr. Also, admini-stration of 1$\frac{1}{2}$ vial(7.5 ml) of PG600$^{ }$ treated group had a great number of CH and recovered oocytes.covered oocytes.

• 한국의료질향상학회지
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• 제2권2호
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• pp.156-171
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• 1996

Background: Nosocomial infection control is one of important means to assure the quality of medical care in the hospital, however, it has been neglected by most of the hospital personnels. Of nosocomial infections, urinary tract infection is the highest incidence, which is related to the indwelling catheter. It is, therefore, necessary to pay primary attention to the patients with the indwelling catheter in intensive care unit in order to control nosocomial Infection and to improve the quality of medical care in the hospital. Methods : The subjects of this study were patients with indwelling catheter who were admitted to the ICU of Pusan Paik Hospital from March 1994 to May 1995. The author calculated UTI rate among the subjects through the cultivation of the urine, identified the related factors of the UTI through brain storming of study team and head nurses working at ICU, and analized the effectiveness of the proposed approaches through comparing the infection rates of before and after activities. Results : The major activities carried out by the study team were to conduct in-service education programs for the staffs working at ICU about the importance of the nosocomial infection control in QA, and nursing intervention to reduce the UTI rate among the patients with indwelling catether. 1. The major nursing interventions that the study team had implemented were as follows ; 1) Drainage system was changed from partial open system to completely closed system. 2) Bladder irrigation which was routinely practised in all patients stopped among the noninfected patients. 3) Bladder irrigation set was changed to the disposable one. 4) Catheter was inserted under the anesthesia for patients to be operated. 5) Male patient receiving wrapped with gauze after perineal care was not wrapped. 6) Clamp which had not been before was newly attached to drainage tube. 7) Urine bag which had been packed into a lot of pieces was done into each piece. 8) The interval of change of indwelling catheter had regularly been four weeks, however it was used continously until it worked well. 9) Catheter was attached well at the defined site. 10) Paper towel was used instead of cotton towel. 11) Mats at the entrance were removed and cleansing of wards was enhanced. 2. The UTI rate by month was 34.4% in maximum and 9.8% in minimum during the period of this study, however it had gradually decreased. After 6 months from initiating infection control activities, the trend of rates was relatively stable. It was identified that UTI rate was different by season 12.5% in winter and 27.2% in summer. 3. Utilization rate of indwelling catheter was maintained at under 50%, but it was increased above 57% from April 1995. 4. The number of bladder irrigation sets used per day was 33.3 sets in maximum and 2.8 sets in minimum. The number used per day were also remarkably deceased. Conclusion : It was found that a program to control UTI could contribute to nosocomial infection control, and it was, in turn, a mean to assure the quality of medical care in the hospital. The nursing interventions which this study team had implemented were effective in the reduce of UTI rates.

• 여성건강간호학회지
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• 제5권2호
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• pp.222-229
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• 1999

These days, as the society has been in the trends of highly industrialized and the family has been downsized, there is remarkably increasing number of women who follow occupation. These changes have made it more difficult for the family to help post-partum mother, which had been performed in side of house. By the help of social believe that during at least 1 month after childbirth professional nursing program is indispensable for both maternity protection and physical-mental recuperation, now many post-partum care centers for post-partum mother have been in operation. Although these post-partum care center have in use for a long time, no study was performed before this study on the same subject. Data were analyzed using by SAS. The results of study are as follow : 1. The general features of the user of the post-partum care center. The predominant band of user's age is extended from 26 to 30. The users are mainly housewives and they are in higher level of incomes and educations. As for the feature of delivery methods, they performed the normal spontaneous vaginal delivery method by 58.0% and the Caesarean operation method by 42.0%. As for the sexuality for babies, 59.3% of infants are male, and 40.7% are female. The highest delivery order of users is first and admission after 1-3days delivery is highest. 2. The results for the investigation into the actual condition of the post-partum care center are as follow : About the main reason for entrance of the post-partum care center was found to be the needs for the better nursing programs for recuperation after childbirth. This demands are also supported by their husbands. The average length of stay in the post-partum care center is 17.6 days and the besides promised expense ; powdered milk, milk-suckers, disposable dippers, skin cares, body shape cares, entrophics, injections. The post-partum have private rooms for mother and infants. Over the half of average expense is 229 million won. They are paying accessory fees the post-partum care center have similar step organization : the nurses, the skin carers, the cleaners. Mostly both ways of feeding powdered milk and breast feeding are in use, and mother's milk is preserved in the night time to be given to infant by nurse in charge. 3. The results of the investigation on users' nursing demand to the post-partum care center and satisfaction are as follow : The ranking order of nursing demand of mothers who used the is that ; infant care demands, environmental demands, emotional and mental care demands, education and training demands. As much as 70% of the respondents have dissatisfaction in nursing program, The ranking order of service satisfaction of mothers who used appears to be higher following order ; satisfaction in infant care demand, satisfaction in physical nursing demand, satisfaction in emotional and mental nursing demand, satisfaction in education and training demand, satisfaction in environment nursing demand. The results of pearson correlation. between nursing demand and service satisfaction of mothers who used are found to be relative noticeable in the level of 0.05. only infant care. The 61.7% of the women who used the post-partum care center. are responding that they will reuse the same post-partum care center again.

• Journal of Chest Surgery
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• 제4권2호
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• pp.69-80
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• 1971

Total body perfusion using Rygg-Kyvsgaard Heart-Lung-Machine, Mark IV, Polystan was attempted in the dogs by the hemodilution method with total prime of buffered Hartman's solution and under hypothermia. The first of all, the functions of Rygg--Kyvsgaard Heart-Lung-Machine and the effects of the hemodilution perfusion by buffered Hartman's solution was studied. At the same time the changes of blood pressure, oxygen consumption, and influence on the blood pictures were observed before, during, and in 1-3 days after perfusion. Hemodilution rates were the average 74. 22cc/Kg(the ranges of 67 to 81 cc/Kg) and perfusion flow rates were maintained in the mean 62. 6cc/Kg/min., Although it was possible to check up to 87 cc/ Kg/min. The total body perfusion continued for 60-80 minutes. Hypothermia was employed between $36^{\circ}C$ and $32^{\circ}C$ of the rectal temperature. Arterial pressure was ranged approximately between 68mmHg and 149mmHg, but generally, it was maintained over 80mmHg. Venous pressure was measured between 6.5cm $H_2O$and 11.5cm $H_2O$. Optimum oxygenation can be expected when oxygen flow into the disposable bubble oxygenator was maintained approximately at 3.5 L/min .. Inthis way, the oxygen contents were measured in the mean value of 13.11${\pm}$O.56 vol. % of arterial blood and 8.67+1.08 vol.% of venous blood(P${\pm}$0.86 vol.% in arteriovenous oxygen difference and 2. 97${\pm}$0.62cc/Kg in oxygen consumption were calculated. According to these dates, it is as plain as pikestaff that excellent oxygenation and good tissue perfusion was accomplished. Erythrocyte, hemoglobin and hematocrit were decreased about 38% during extracorporeal circulation and these were not recovered until 1-3 days after perfusion. These decrease was resulted from relatively high degree of hemodilution rate and no blood transfusion to compensate during these experimental studies. The platelets were also decreased about 76% during perfusion, but on the contrary, it was increased progressively after perfusion and in 1-3 days after perfusion was returned to the control level. Leucocyte were also decreased during perfusion, but it was increased progessively after perfusion and in 1-3 days after perfusion exceed the control level. This increase was resulted from postoperative infection of the wound, but its analysis were not changed significantly.

• 대한구순구개열학회지
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• 제4권1호
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• pp.1-11
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• 2001

Disposable blade is widely used for palatal and oral mucosal incision in oral and maxillofadal surgery nowadays, But its design and durability need for improvement, Especially, there are so many hard tissues intraoral area, such as bone and tooth, therefor the sharpness of the surgical blade was easily destroyed, The purpose of this study was to make basic data for developing new design of surgical blade using in oral and maxillofacial area including for the patients who have cleft lip and palate deformities, Some questionnaires about the usefulness of currently used surgical blades were sent to 150 dentists, the 54 of them made a reply, Secondly, The used-once blade and fresh new blade were examined under the scanning electron microscope with the 4000-times magnification, Lastly, the tissue reaction following the surgical incision with a fresh-new and a used blade on rat buccal cheek mucosa and hard palate was evaluated with light microscope with hematoxilin-eosin staining, The time interval from the surgical trauma to taking a sample were 1 day, 3 days, 7 days, and 14 days, At each time schedule, 2 Sprague-Dawley rats were sacrificed, Many dentists were agreed to need for changing the design of the surgical blades and also demand to improve the durability of the blades, They were also eager to adopt the new design of blade if it was available, The blade used in surgical extraction procedure was heavily damaged in its sharpe edge of number 15 blade, The histological differences were not prominent, but the delayed healing was detected in buccal mucosal defects especially in the surgical group with used blade, There are slight different changes in hard palatal defects between a used and a new blade group, In this study, we could find that there are imperative demanding on improvement of surgical blade design and durability for oral and maxillofadal area, The blade currently using in surgical extraction was easily damaged, The animal model of this study was not perfect for the purpose of this study.

• 한국사회복지학
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• 제66권3호
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• pp.231-251
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• 2014

정부는 부유층 기초연금 수급과 관련한 부정적 여론에 대응하기 위해 2014년 7월부터 6억 이상 자녀명의 주택 거주노인에 대해 소득인정액 산정 시 무료임차추정소득을 부과하고 증여재산 산정기간을 연장하는 등의 방안을 실시하고 있다. 본 연구는 이러한 개혁안의 효과성과 적정성을 평가하기 위해 '한국복지패널(7차자료)'을 활용한 가구별 소득인정액을 산출하여 부유층 노인의 수급실태와 재정소요규모를 추정하고, 정부안의 모의분석을 통해 수급자격 변동 등 정책효과를 살펴보았다. 분석결과, 첫째 기존 연구경향을 반영하여 부유층의 기준을 소득상위 10%로 설정할 경우 부유층 노인수급가구의 규모는 전체 수급가구의 2.9%이며, 이로 인한 재정지출규모는 총 급여지출액의 2.6%에 불과한 것으로 나타났다. 둘째, 가처분 소득, 부채, 사적이전을 고려할 때 정부안이 적용되는 가구의 경제수준은 정부안이 적용되지 않는 유사 경제수준의 가구보다 월등하게 높다고 보기 어려우며, 실제 정부안이 시행된다 하더라도 수급권 조정이 발생되는 가구는 극소수(약 0.7%)에 불과하였다. 셋째, 정부의 대책은 노인부양 가구를 차별할 뿐 아니라, 전체 노인가구를 대상으로 선정기준액을 새롭게 설정하지 않는 한 단순 급여삭감 조치에 불과하여 기초연금제도는 전반적으로 후퇴할 것으로 판단된다. 이러한 분석결과를 토대로 본 연구는 정부의 개혁방안이 과학적 예측과 진지한 토론이 부재한 상태에서 일부 부유층 노인의 급여수급에 대한 부정적 여론에 편승하여 개인 노후소득보장제도인 기초연금에 사실상의 부양의무자 기준을 적용함으로써 제도를 잔여화하고 향후 복지삭감에 유리한 정책환경을 조성하는 프로그램적-체계적 복지축소전략이라는 점을 강조하였다. 더욱 우려할만한 점은 이러한 정부안이 우리나라 노후소득보장제도의 기반을 흔들 수 있는 적대적인 사안임에도 불구하고, 최근 기초연금 논의에서 거의 주목받지 못하고 있다는 것이다.

• 콘크리트학회논문집
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• 제18권3호
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• pp.303-312
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• 2006

본 연구에서는 GFRP 보강근의 인장특성치 시험을 위한 그립 시스템의 적합성을 검증하기 위하여 캐나다 규준에서 제안하는 그립(CSA 그립), ASTM에서 제안하는 그립(ASTM 그립) 및 프리스트레싱 강연선의 정착에 일반적으로 사용되는 쐐기형 그립 등을 사용하여 GFRP 보강근에 대한 인장특성치 시험을 실시하였다. 또한, 현재 외국에서 상용화되고 있는 대표적인 2종류의 GFRP 보강근(나선형 GFRP 보강근, 모래분사형 GFRP 보강근) 및 국내에서 자체 제작한 원형 GFRP 보강근을 대상으로 하여 인장특성치 분석을 위한 시험을 실시하고 각각의 제안된 그립의 적용성 여부를 검토하였다. 본 시험에 사용된 시험편의 제작, 가력 및 측정장치의 설치 등은 CSA S806-02에서 제안하는 권고사항에 따라 실시하였다. 외국의 상용화된 GFRP 보강근에 대하여 그립의 종류를 달리하여 실시된 본 시험결과에 의하면, CSA 그립을 사용하여 시험된 GFRP 보강근의 인장강도가 가장 높은 값을 보이는 것으로 나타났다. 그러나 ASTM 그립을 사용한 시험편에서 관측되는 강도저하 현상은 CSA 그립을 사용한 시험체에 비하여 약 10% 미만인 것으로 관측되었다. 한편, CSA 그립은 제작공정이 까다로울 뿐만 아니라 재사용이 불가능하여 경제성 측면에서도 불리한 것으로 파악되었다. 따라서, 실용적인 측면에서 판단하면 GFRF 보강근의 인장시험에는 ASTM 그립이 적절할 것으로 판단된다.

• 한국안광학회지
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• 제15권2호
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• pp.137-144
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• 2010

목적: 본 연구는 프리즘 밸러스트 디자인 원데이 토릭 소프트 콘택트렌즈의 임상적 성능을 평가하고 안경교정 상태와 시기능의 질을 비교하기 위해 실시하였다. 방법: 대상자는 구면 -2.75 D이고 -0.75 DC에서 -2.25 DC 사이의 직난시를 갖는 건강한 대학생 15명(30안)을 대상으로 프리즘 밸러스트 디자인 렌즈를 양안에서 처방하여 2주간 착용시켰다. 대상자들은 토릭렌즈의 임상성능(렌즈 안정 위치, 중심안정, 렌즈 움직임, 타이트한 정도, 렌즈 안정성, 회전 회복, 자각증상)을 평가하고 양안시 검사 값 및 대비감도를 초기 방문과 2주간 적응 후 검사하여 안경교정 상태와 비교였다. 결과, 프리즘 밸러스트 디자인의 토릭 소프트 콘택트렌즈를 2주간 착용한 후에 렌즈 방향안정, 회전 회복, 자각증상을 평가한 결과, 적응 전보다 향상되었다. 양안시 검사 값과 대비감도가 안경 착용 상태와 비교할 때 통계적으로 유의한 차이가 없는 것으로 나타났다. 결론: 프리즘 밸러스트 디자인의 토릭 소프트 콘택트렌즈를 착용한 후 임상적 기능이 증진하였다. 양안시 검사값과 대비감도가 안경교정 상태와 차이가 없는 것으로 평가되었다. 본 연구를 통해서 토릭 소프트 콘택트렌즈 착용자가 안경교정 자와 유사한 시생활을 영위할 수 있는 것으로 사료된다.