• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.16 no.7 s.112
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• pp.739-745
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• 2006

This paper presents a novel type of hybrid dispensing head for IC fabrication and surface mount technology. The proposed mechanism consists of solenoid valve and piezoelectric stack as actuators, and provides positive-displacement and jet dispensing. The positive-displacement dispensing can produce desired adhesive amount without viscosity effect, while the jet dispensing can produce high precision adhesive amount. In order to determine the relationship between required voltage of the piezoelectric actuator and needle displacement, both static and dynamic analysis are undertaken, In addition, finite element analysis is performed in order to find optimal design parameters. Dispensing flow rate and pressure in the chamber are evaluated through fluid dynamic model.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2006.05a
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• pp.821-826
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• 2006

This paper presents a novel type of hybrid dispensing head for IC fabrication and surface mount technology. The proposed mechanism consists of solenoid valve and piezoelectric stack as actuators, and provides positive-displacement and jet dispensing. The positive-displacement dispensing can produce desired adhesive amount without viscosity effect, while the jet dispensing can produce high precision adhesive amount. In order to determine the relationship between required voltage of the piezo actuator and needle displacement, both static and dynamic analysis are undertaken, In addition, finite element analysis is performed in order to find optimal design parameters. Dispensing flow rate and pressure in the chamber are evaluated through fluid dynamic model.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.35 no.11
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• pp.1127-1131
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• 2011

We report on a pumpless cell culture chip in which a constant medium perfusion rate is maintained by balanced droplet dispensing. Previous chips had a decreasing perfusion rate due to the decreasing hydraulic-head difference ${\Delta}h$ between the inlet and drain. However, the present chip maintains a constant medium perfusion rate due to the constant ${\Delta}h$ between the inlet and drain maintained by balanced droplet dispensing. The perfusion rate Q was measured to be 0.1-$0.3{\mu}l$/min with a maximum deviation and error of 9.96% and 6.92%, respectively. In the perfusion culture (Q = 0.1-$0.3{\mu}l$/min), the maximum growth-rate of H358 cells was measured to be $57.8%{\pm}21.1%$ per day, which is 1.9 times higher than that of a static culture. The perfusion culture also resulted in higher cell viability than a static culture. The present chip offers a favorable environment with a high growth-rate and viability and thus has potential for use in the integrated cell culture system.