• 말소리와 음성과학
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• 제3권3호
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• pp.181-189
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• 2011

The present study aimed to determine the phonological errors of children in Korean-Vietnamese speaking multicultural families through comparison analyses with those of Korean monolingual peers with phonological disorders. The subjects were 38 children aged about 4-6 years. To examine phonological errors, the Urimal Test of Articulation and Phonation (words) was used. Performances were analyzed by frequency. The results showed some differences between the two groups. There was a tendency for children in Korean-Vietnamese speaking multicultural families to show a higher frequency of phonological errors than Korean monolingual children with phonological disorders. However, the former showed lower error percentages in a few error patterns than the latter such as syllable final consonant deletion, showing similar patterns to those of the normal children. They also showed very unique error patterns such as the highest error percentage in palatal affricates. It remains to be seen if these error patterns are just delay in acquisition or phonological disorders.

• 생물정신의학
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• 제21권4호
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• pp.128-140
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• 2014

Anxiety disorders are characterized by dysregulation of neuroendocrine, neurotransmitter and neuroanatomical functions. Substantial advances in research method offered new insights into the neurobiologic mechanisms in anxiety disorders. Advances in molecular biology have enabled illumination of hormone and neurotransmitters that have important roles in anxiety. The neuroanatomic circuits related to anxiety are also being elucidated by improvements in neuroimaging technology such as structural and functional magnetic resonance imaging. This article reviews the research data in relation to the neurobiology underlying fear and pathologic anxiety and discusses their implications for development of biological treatments for anxiety disorders.

• Journal of Preventive Medicine and Public Health
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• 제46권sup1호
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• pp.12-21
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• 2013

Several epidemiological studies have shown that exercise (EX) and physical activity (PA) can prevent or delay the onset of different mental disorders, and have therapeutic benefits when used as sole or adjunct treatment in mental disorders. This review summarizes studies that used EX interventions in patients with anxiety, affective, eating, and substance use disorders, as well as schizophrenia and dementia/mild cognitive impairment. Despite several decades of clinical evidence with EX interventions, controlled studies are sparse in most disorder groups. Preliminary evidence suggests that PA/EX can induce improvements in physical, subjective and disorder-specific clinical outcomes. Potential mechanisms of action are discussed, as well as implications for psychiatric research and practice.

• Journal of Genetic Medicine
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• 제18권1호
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• pp.16-23
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• 2021

GLB1-related disorders comprise two phenotypically unique disorders: GM1 gangliosidosis and Morquio B disease. These autosomal recessive disorders are caused by b-galactosidase deficiency. A hallmark of GM1 gangliosidosis is central nervous system degeneration where ganglioside synthesis is highest. The accumulation of keratan sulfate is the suspected cause of the bone findings in Morquio B disease. GM1 gangliosidosis is clinically characterized by a neurodegenerative disorder associated with dysostosis multiplex, while Morquio B disease is characterized by severe skeletal manifestations and the preservation of intelligence. Morquio B disease and GM1 gangliosidosis may be on a continuum of skeletal involvement. There is currently no effective treatment for GLB1-related disorders. Recently, multiple interventions have been developed and there are several ongoing clinical trials.

• PNF and Movement
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• 제17권1호
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• pp.145-156
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• 2019

Purpose: This study suggests clinical reasoning strategies for therapists with little experience in clinical reasoning for the evaluation and treatment of patients with neurological disorders. Methods: The suggested method was the mnemonic PT STRESS whose initials represent the body structure and functions that can affect the activity limits and the items that can cause problems at the functional level in patients with neurological disorders. Results: PT STRESS stands for pain (P), ability of the trunk (T), sensation (S), tone (T), range of motion (R), emotion and endurance (E), muscular strength (strength), and stability (S). It tests and measures problems in the body structure and functions. Conclusion: This study suggests easy clinical reasoning strategies that can be used by therapists who have insufficient experience in the evaluation or treatment of patients with neurological disorders. However, more factors need to be considered in the future with regard to clinical reasoning of the diverse problems of patients with neurological disorders.

• 대한신경과학회지
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• 제36권4호
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• pp.280-288
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• 2018

Vertigo/dizziness is a common complaint in patients who are seeking a primary health clinic. Vertigo is traditionally attributed to damage of the vestibular system. Many peripheral and central vestibular disorders are usually presented with vertigo. However, patients with benign paroxysmal positional vertigo (BPPV), a leading cause of vertigo, may present with postural lightheadedness, near faint, imbalance rather than true vertigo. On the contrary, patients with orthostatic hypotension may present with true spinning vertigo, not dizziness. Persistent postural perceptual dizziness, a second most common cause of dizziness (after BPPV), is mainly occurred after organic vestibular disorders such as BPPV or vestibular neuritis, and classified as a chronic functional vestibular disorder. This article describes non-vestibular disorders presenting dizziness and/or vertigos, which conditions may be misdiagnosed as structural vestibular disorders.

• 대한안전경영과학회지
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• 제23권2호
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• pp.25-30
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• 2021

The possibility of developing musculoskeletal disorders increases with the length of service of the worker. Musculoskeletal disorders can occur when performing repetitive and forceful movements. Therefore, Cargo drivers operate repeatedly in the wrong posture for a long time. When loading and unloading a cargo, the cargo driver works repeatedly with force. Cargo operators are also exposed to musculoskeletal disorders in the working environment due to poor posture and repetitive movements. In this study, we are going to conduct a study on the level of awareness and prevention of the possibility of musculoskeletal disorders in cargo drivers for long periods of time. As a result of the study, the factors that cause musculoskeletal disorders in each group can occur during the long-term operation and preparation of drivers.

• Perspectives in Nursing Science
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• 제18권1호
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• pp.1-9
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• 2021

Purpose: This study was undertaken for developing a cognitive behavioral therapy (CBT) program for adolescents with eating disorders. Methods: The specific process for the development of this program involved establishing a program goal, analyzing existing CBT programs, and constructing a CBT program. Results: The program consisted of 12 sessions, which is shorter than typical programs conducted for people with eating disorders, in order to reduce the dropout rate. Each session was 40~60 minutes long, and included the use of the psychoeducation, Dysfunctional Thought Record, and activity planning. The participants attended 5 sessions individually and 7 with their family members. Conclusion: This study presented a 12-session CBT program for adolescents with eating disorders. These results will provide valuable data for developing effective programs to improve the quality of life of these adolescents.

• Clinical and Experimental Pediatrics
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• 제65권2호
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• pp.56-64
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• 2022

Cerebrospinal fluid (CSF) is a dynamic metabolically active body fluid that has many important roles and is commonly analyzed in pediatric patients, mainly to diagnose central nervous system infection and inflammation disorders. CSF components have been extensively evaluated as biomarkers of neurological disorders in adult patients. Circulating microRNAs in CSF are a promising class of biomarkers for various neurological diseases. Due to the complexity of pediatric neurological disorders and difficulty in acquiring CSF samples from pediatric patients, there are challenges in developing CSF biomarkers of pediatric neurological disorders. This review aimed to provide an overview of novel CSF biomarkers of seizure disorders, infection, inflammation, tumor, traumatic brain injuries, intraventricular hemorrhage, and congenital hydrocephalus exclusively observed in pediatric patients.

• Journal of Oral Medicine and Pain
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• 제47권4호
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• pp.174-182
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• 2022

In chronic temporomandibular disorders (TMDs), constituent tissues such as muscles are sensitive to pain and psychological stress, which negatively affect the quality of life. In addition, since chronic TMDs is often accompanied by diseases such as psychological disorders and other chronic pain disorders, the diagnosis of those diseases and patient referrals are mandatory. The management of chronic pain in TMDs requires a multidisciplinary and holistic approach. Pharmacological therapy using cyclobenzaprine, serotonin and norepinephrine reuptake inhibitors, tricyclic antidepressants, progressive relaxation, and psychological approaches using cognitive behavioral therapy such as shifting negative thoughts about pain are all valid treatment options.