• Korean Journal of Biological Psychiatry
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• v.5 no.1
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• pp.134-137
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• 1998

Authors report a case of separation anxiety disorder, which developed as a side effect during haloperidol treatment of Tourette syndrome(TS). In this case, 14 years old boy developed attention deficit symptoms during his infancy. At 4th grade of primary school, he developed vocal tic, motor tic, and coprolalia. With 5mg/day of haloperidol treatment his symptoms of TS were subsided. During the treatment, he developed features of separation anxiety disorder, including dependence, pleading, clinging, and sadness. Symptoms of attention deficit and separation anxiety disorder were improved by 25mg/day of imipramine treatment. During haloperidol treatment of TS, careful observation may be needed whether separation anxiety disorder-like symptom develops.

• Journal of the Korean Data and Information Science Society
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• v.28 no.6
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• pp.1403-1414
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• 2017

The purpose of this study is to examine the factors that affect eating disorder of female adolescents. Collecting data from 297 female adolescents, we carried out logistice regression on SPSS Win 20.0. The significant predictors of eating disorder for female adolescents were BMI, body-shape satisfaction, subjective body-fatness, experience weight control (diet control and exercise), self-control, and body esteem. The results of this study may help to design a school health nursing program which treats female adolescents eating disorder.

• The Journal of Pediatrics of Korean Medicine
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• v.19 no.2
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• pp.153-163
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• 2005

Objectives : The purpose of this study is to find out whether Ondam-tang has any effects on adolescence with anxiety disorder Methods : The subject is in regard to 1 case with anxiety disorder who adnutted at ${\bigcirc}{\bigcirc}$ Oriental Medical hospital from 29th of June to 7th of July. The herbal therapy (Acupuncture, Moxa, Aroma therapy) is applied. Results : After treatment, in a week, most of symptoms (insomnia, anxiety, the problem of verbal expression, chest discomfort, palpitation, anorexia, digestion, headache, dizziness, thirst, eye discomfort, etc) were subsided. Conclusion : Anxiety disorder is similar to Simdamhugup in Oriental medicine. Ondam-tang has been used for long time for treatment on Simdamhugup. Ondam-tang is effective medication for adolescence with anxiety disorder, but more studies about adolescence and Oriental approach of psychiatries are needed.

• The Journal of Pediatrics of Korean Medicine
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• v.35 no.3
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• pp.28-42
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• 2021

Objectives The purpose of this study is to investigate the effect of Tuina treatment for children with Autism Spectrum Disorder (ASD), and to propose guidance to future studies or application in clinical setting. Methods The articles published from year 2000 to May 2021 by China National Knowledge Infrastructure (CNKI) were searched by setting up field as '中醫學', '中藥', '中西醫結合' and by setting up keyword as '小儿自閉症', '儿童自閉症', '自閉症譜系障碍', 'Autism', 'Autism spectrum disorder' that corresponds to participant and '推拿', '導引', '按摩', 'Tuina', 'massage'. Results Nine selected articles were analyzed and summarized by authors and year published, characteristics, diagnostic criteria, treatment methods and contents, treatment duration, evaluation criteria and results of the study. The articles were also reviewed by reported side effects, and evaluated the quality of the study according to Cochrane Handbook's Risk of Bias 2 (RoB 2) assessment of the Randomized Control Trial (RCT) articles. All studies used Tuina treatment to achieve effective results for pediatric autism spectrum disorder. Conclusion Pediatric Tuina treatment (TM) is a non-invasive treatment that does not stimulate patients with unstable ASD but increase patient adherence, and can be safely and simply operated. Therefore, pediatric Tuina treatment is worth utilizing as a clinical basis for further development of ASD treatment.

• Journal of Korea Game Society
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• v.19 no.1
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• pp.135-146
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• 2019

World Health Organization reveals its plan for listing 'Gaming Disorder' on the 11th International Disease Codes (ICD-11) in 2018 and it opens hot debate among scholars on its validity and timeliness. Korea, however, seems to have avoided the issue without appropriate academic refutation. In this paper, we review past academic studies related to game addiction or disorder focused on their validity of disorder measurement tools, research designs and the effect of neuroimaging studies. This analysis reveals that excessive use of gaming is not sufficient to register it as a disease and there is a risk of stigmatizing healthy gamers.

• Journal of Oriental Neuropsychiatry
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• v.30 no.3
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• pp.295-304
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• 2019

Objectives: The purpose of this case report was to propose Yangshimtang-Gamibang on three patients diagnosed with acute stress disorder. Methods: Yangshimtang-Gamibang was treated on three patients diagnosed with acute stress disorder after experiencing a traffic accident. The effects of Yangshimtang-Gamibang were evaluated through BAI (Beck Anxiety Inventory), NRS (Numerical rating scale), NDI (Neck Disability Index), ODI (Oswestry Disability Index), respectively, and quality of sleep was assessed with total sleep time and number of times waking up during sleep. Results: After the treatment, there was significant decrease in the value of BAI score, a measurement of anxiety, as well as the value of NRS, NDI, ODI, a measure of pain. Also, the sleep quality of three patients improved. Conclusions: The results indicate that Yangshimtang-Gamibang may have an effect on people with acute stress disorder who recently experienced a traffic accident.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.32 no.2
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• pp.51-62
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• 2021

Objectives: Tic disorder is a neurodevelopmental disorder characterized by multiple involuntary movements of muscles or vocalization. Although tic symptoms subside as the patient ages, some patients suffer from significant functional impairments related to severe tic symptoms. This manuscript aimed to review the latest scientific evidences for the effect of cognitive-behavioral interventions on tic disorder. Methods: The relevant studies were identified by searching medical research databases. We focused our search on studies published between 2000 and 2020 in order to reflect the latest scientific evidence. A total of 821 articles were identified in the initial database search and 27 articles were finally included for the review after the exclusion of duplicated and irrelevant articles. Results: Behavioral therapies including habit reversal training, Comprehensive Behavioral Intervention for Tics, and exposure and response prevention were the most widely studied interventions for tic disorder and are recommended as first-line treatments for tic disorders with high confidence. Cognitive psychophysiologic approaches were also reported to be effective. Conclusion: Further studies are needed to support the future treatment of tics with low-cost and more widely available treatments, in order to ensure better treatment outcomes.

• Journal of the Korean Society of Food Culture
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• v.21 no.2
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• pp.193-201
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• 2006

The purpose of this study was to examine the relationships of snack intake and ADHD (Attention Deficit Hyperactivity Disorder) among 284 children aged $4{\sim}7$ years. The degree of ADHD (Attention Deficit Hyperactivity Disorder) were assessed by both children's mother and their teachers using Behavior check list. The subjects who had a higher ADHD (Attention Deficit Hyperactivity Disorder) score ate more pizza, hamburger, chicken, processed milk, carbonated beverage. These results indicate ADHD (Attention Deficit Hyperactivity Disorder) were related positively for snack(pizza, hamburger, chicken, processed milk, carbonated beverage etc.) intake.

• Herbal Formula Science
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• v.11 no.2
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• pp.185-196
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• 2003

Depression is very common mental disorder, so many people suffer from it, which makes the treatment of depression important. Many drugs to treat depression were developed and being prescripted. But they have a lot of side effects, so it needs to develop drugs without side effects or with less side effects. Herbal medicines have been used to treat not only physical disorder but also mental disorder and it has been reported that they have less side effects. Therefore, there is the need to discover and use herbal medicine with antidepressant effect. The purpose of this study was to reseach Antidepressant effect of Licium chinense Mill. and its influence on serotonin and its metabolite of depression model rats. We used 'forced swimming test(FST)' to know antidepressant effect of Licium chinense Mill. and HPLC to check the influence on serotonin and its metabolite(5-HIAA) of Licium chinense Mill. after rats' brains were divided into cerebral cortex, striatum, hypothalamus and hippocampus. The results were obtained as follows : In the study of antidepressant effect by 'forced swimming test(FST)' method, Licium chinense Mill. had a significant antidepressant effect. In the study of influence on serotonin and 5-HIAA by HPLC, Licium chinense Mill. mainly increased serotonin and 5-HlAA of cerebral cortex and striatum signigficantly among 4 parts of rat's brain above-mentioned. These results suggest that Licium chinense Mill. has antidepressant effect that may be related with the increase of serotonin and its metabolite as its mechanism, but more precise experiments will be need to prove their relation.

• Korean Journal of Clinical Pharmacy
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• v.28 no.3
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• pp.204-215
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• 2018

Background: In this systematic review and meta-analysis, the effect of metformin on weight loss was assessed to determine whether metformin should be recommended for the prevention or treatment of weight gain in patients receiving antipsychotic medication for the treatment of schizophrenia or schizoaffective disorder. Methods: The PubMed, Embase, and Cochrane Library databases were searched for all published randomized controlled trials (RCTs) from inception to June 2018. In addition, the references of relevant articles were also examined. Using Review Manager 5, the pooled estimates of the weighted mean difference (WMD) of the changes in body weight and body mass index (BMI) and the corresponding 95 % confidence intervals (CIs) were calculated. Results: The meta-analysis included 15 RCTs. The pooled analysis showed that compared with placebo, metformin led to significant reductions in body weight (WMD: -2.09, 95% CI: -2.59, -1.60; p<0.00001) and BMI (WMD: -0.90, 95% CI: -1.08, -0.72; p<0.00001). The effect of metformin on weight loss was greater in patients receiving olanzapine than in patients receiving clozapine (body weight, WMD: -2.39, 95% CI: -3.76, -1.02; p=0.0006 for olanzapine; -1.99, 95% C: -3.47, -0.51; p=0.009 for clozapine; BMI, WMD: -1.15, 95% CI: -1.74, -0.57, p=0.0001 for olanzapine; WMD: 0.76, 95% CI: -1.23, -0.28; p=0.002 for clozapine). Conclusion: Metformin can be recommended to manage olanzapine-induced weight gain in patients with schizophrenia or schizoaffective disorder. The magnitude of the reductionss in body weight and BMI implieds that the use of metformin to attenuate olanzapine-induced weight gain can minimize the risk of coronary heart disease.