• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.86.1-86.1
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• 2003

High-dose extracts from artichoke leaves are traditionally used for treatment of stress related disorder, that is, hepatic disease, dyspeptic disorder, hyperlipidemic disorder and diuretic disorder. The aim of this study was to investigate anti-stress effects of Artichoke extract(Archoke juice produced from Choa company). The experiments were performed with the use of young(6-8 weeks of age) male mice of ICR stain weighing between 20 and 25 g at the time of first treatment with Archoke juice. The were grouped normal, control, Ginseng, diazepam and Arcoke juice group. (omitted)

• 대한한의학회지
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• 제42권3호
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• pp.139-152
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• 2021

Objectives: The purpose of this review is to investigate the latest traditional Chinese medicine clinical studies on pediatric tic disorder with Tuina treatment and propose the directions of future studies and clinical applications. Methods: To obtain data from CNKI, set the field by '中醫學', '中藥', '中西醫結合' and used keywords '抽动障碍', '抽動穢語綜合', '小兒抽动', '兒童抽动' and '推拿', '導引', '按摩', 'Tuina', 'massage' in cross combination way. Results: 12 clinical studies were selected. These studies were analyzed by author & year, subjects, diagnostic criterion, evaluation criterion, syndrome differentiation, treatment period, methods& results, frequent acupoints and assessment of the quality of studies. All of reports achieved effective therapeutic results on the pediatric tic disorder with Tuina treatment. Conclusion: Tuina treatment has a positive effect and are easily accepted by children who have fear and rejection to traditional Korean Medicine such as acupuncture and Herbal remedy. It is also safe and simple to operate. So the Tuina treatment is worthy to disseminate potential for further development in the treatment of pediatric tic disorders.

• 대한한의학회지
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• 제43권1호
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• pp.180-189
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• 2022

Objectives: This study aims to find out the effect of herbal medicine on sleep disorder in developmental delayed children. Methods: 2 patients were treated by herbal medicine. For the progress evaluation, we used The Children's Sleep Habits Questionnaire (CSHQ). Results: The clinical symptoms were improved after the treatment. Conclusion: This study reports that the herbal medicine improved sleep disorder in developmental delayed children, but further studies are needed to clarify the effectiveness of the treatment.

• 대한감각통합치료학회지
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• 제18권1호
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• pp.56-72
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• 2020

목적 : 주의력결핍 과잉행동장애(Attention Deficit Hyperactivity Disorder; ADHD)의 증상을 완화시키는데 있어 부모 훈련 중재(Parent Training Intervention)의 효과를 분석하고 어떠한 효과가 있는지 그 근거를 제시하는데 목적이 있다. 연구방법 : 2009년부터 2019년까지 10년간 해외 학술지에 게재된 문헌을 Proquest, Scopus 데이터베이스를 통하여 수집하였다. 검색용어는 (ADHD OR Attention Deficit Hyperactivity Disorder) AND (Parent OR Mother OR Father) AND (Training OR Program OR Therapy OR Intervention) AND (Randomized OR Randomised OR Randomly)를 사용하였다. 연구의 질적 평가를 위해 PEDro척도를 활용하였고, Comprehensive Meta-Analysis 3.0을 통해 메타분석을 실시하였다. 결과 : 1차 검색된 628개의 연구를 확인하였고, 최종 20개의 논문을 선정하였다. ADHD 아동에 대한 부모 훈련 중재의 전체효과크기(0.431) 및 부모 대상 중재(0.391), 부모-아동 대상 중재(0.639)는 모두 중간 효과크기로 나타났다. 부모 대상 중재는 ADHD 증상-과잉행동 및 충동성(0.921), 아동 행동(1.075), 아동 정서(0.834)에서 큰 효과크기가 나타났으며, 부모-아동 대상 중재는 ADHD 증상-과잉행동 및 충동성(0.922), 아동 정서(1.335), 반항성 및 품행장애(2.555), 학교 기능 및 사회기술(0.990)에서 큰 효과크기가 나타났다. 이질성 검정 결과 유의미한 결과가 나타나 랜덤효과모형을 선택하였다. 결론 : 부모 훈련 중재가 ADHD 아동의 증상에 미치는 효과를 알 수 있었다. 이는 작업치료사에게 임상적 근거를 제공하기 위한 근거 자료로 사용될 수 있을 것이다. 추후에는 국내실정에 맞는 부모 훈련 중재와 관련된 다양한 연구들이 진행되어야 할 것이다.

• 대한지역사회작업치료학회지
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• 제7권1호
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• pp.9-16
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• 2017

목적 : 본 연구는 수면장애 동물모델 쥐에게 환경변화를 적용하였을 때, 혈 중 멜라토닌의 변화를 통하여 수면장애 개선 효과를 확인하는데 그 목적이 있다. 연구방법 : 본 연구는 경북 소재의 동물실험실에서 실험을 진행하였고 수면장애 모델의 흰쥐 26마리에게 적용하였다. 3일간 환경변화를 적용한 실험군과 일반 케이지에서 환경변화를 적용받지 못한 대조군의 수면장애 모델 쥐 각각 13마리의 혈 중 멜라토닌의 농도를 확인하였다. 결과 : 수면장애 모델 쥐에게 환경변화를 적용한 결과, 환경 적용 후 실험군에서는 3일간 일별 멜라토닌 농도의 변화는 유의하게 증가하였고(p=.000), 대조군은 3일간 일별 멜라토닌 농도의 변화는 약간의 증가는 있었지만 유의한 변화는 없었다(p=.212). 환경 적용 전, 후 멜라토닌 농도의 변화는 실험군, 대조군 모두 유의한 차이를 보였지만 실험군에서는 멜라토닌 농도의 유의미한 증가가 있었고, 대조군에서는 멜라토닌 농도의 유의미한 감소가 있었다. 결론 : 수면장애 환자가 증가하고 있는 현대사회에서 환자들에게 적용되어지는 환경적용이 수면장애에 어떠한 영향을 주는지 확인하기 위해 동물모델을 제작하였고 인간의 환경변화와 유사한 환경변화를 적용하였으며 이를 통해 수면장애의 개선효과를 확인할 수 있었다.

• 한국융합학회논문지
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• 제13권5호
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• pp.279-286
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• 2022

이 연구는 청소년들의 범불안장애와 스마트폰 과의존의 관계에서 신체활동의 매개효과를 확인하는데 목적을 둔다. 청소년 시기 스마트폰 이용으로 인한 문제점을 해결하기 위한 방안으로 신체활동을 통한 청소년의 건강증진 프로그램의 필요성을 찾고자 하였다. 연구 목적을 위하여 교육부·보건복지부·질병관리청에서 공동으로 실시한 2020년 청소년건강행태조사자료를 이 연구의 분석 자료로 활용하였으며, SPSS 23.0을 이용하여 요인분석, 신뢰도분석, 빈도분석, 다중회귀분석 그리고 3단계 매개효과 분석을 실시하여 검증을 시도하였다. 연구결과 첫째, 범불안장애는 신체활동과 부적(-)인 관계가 있고 신체활동 역시 스마트폰 과의존과 부적(-)인 관계가 있는 것으로 나타났다. 둘째, 범불안장애와 스마트폰 과의존 경험 관계에서 신체활동의 매개효과를 분석한 결과 신체활동은 유의미한 매개변수인 것으로 나타났다. 셋째, 신체활동은 범불안장애와 스마트폰 과의존 경험의 관계에서 부분매개효과가 있다는 것을 확인하였다. 개인 스포츠활동보다는 팀스포츠활동을 통해 신체활동을 높이는 것은 스마트폰사용을 줄이는데 도움이 될 수 있다.

• 한국학교ㆍ지역보건교육학회지
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• 제24권1호
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• pp.17-31
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• 2023

Objectives: The purpose of this study is to identify differences in fear of COVID-19 according to types of positive mental health in college students, and to verify the moderating effect of mental well-being in the relationship between mental disorders and fear of COVID-19. Methods: The results of 1,542 college students' responses to the COVID-19 Fear Scale, Korean Mental Disorder Scale, and Korean Mental Health Scale were analyzed. According to the presence of mental disorders and the level of mental well-being (high, medium, and low) of the participants which were assessed by the Korean Mental Disorder Scale and the Korean Mental Health Scale, participants were classified into five mental health groups. And the difference in fear of COVID-19 between groups was identified by one-way ANOVA. In addition, it was identified whether the moderating effect of mental well-being was significant in the relationship between mental disorders and fear of COVID-19 using hierarchical regression analysis. Results: When participants were classified by positive mental health types, the flourish group had significantly lower fear of COVID-19 than the moderate mental health group and the languishing group. The moderating effect of mental well-being was significant in the relationship between mental disorder and fear of COVID-19. Additionally, the reducing effect of mental well-being upon fear of COVID-19 was greater when the severity of mental disorder was lower. Conclusions: Basically, in the case of groups with mental disorders, efforts to reduce mental disorders should be given first and foremost. In contrast, for groups without mental disorders, psychological interventions to raise levels of mental well-being are likely to help reduce fear of COVID-19.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제19권3호
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• pp.147-155
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• 2008

Objectives: The purpose of this study was to evaluate the efficacy and tolerability of osmotic release oral system-methylphenidate (OROS-MPH) in children with attention-deficit hyperactivity disorder (ADHD) and comorbid psychiatric disorders. Methods: This was an 8-week open label study of OROS-MPH monotherapy. The subjects were 113 children with ADHD aged 6-12 years. Outcome measures were the Korean version of the parent ADHD Rating Scale (K-ARS), Korean version of the Conners Parent Rating Scale (K-CPRS), Clinical Global Impression-Severity and Clinical Global Impression-Improvement. Side effects were monitored using Barkley's Side Effect Rating Scale. We compared the change-over-time in the mean scores of the outcome measure according to the comorbidity of disruptive behavior disorder, depressive disorder, anxiety disorder, and tic disorder. Results: The mean K-ARS and K-CPRS scores were significantly decreased, regardless of the comorbidity. The mean doses of OROS-MPH and dropout rate did not differ significantly according to comorbidity. The OROS-MPH was well tolerated, regardless of the comorbidity. However, children with tic disorder reported a higher frequency of tics or nervous movements between the $2^{nd}\;and\;8^{th}$ week than those without tic disorder. Conclusion: The OROS-MPH is effective for decreasing the symptoms of ADHD, and it is well tolerated, even by patients with comorbid psychiatric disorders.

• 대한불안의학회지
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• 제12권1호
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• pp.1-6
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• 2016

Objective : This study was performed to confirm the hypothesis that the more one applies positive thinking, the less severe the symptoms of stress and the better the therapeutic responsein panic disorder and major depressive disorders. Methods : The study included 50 subjects with confirmed diagnoses of panic disorder or major depressive disorders. Positive thinking was assessed using Positive thinking scale. Beck Depression Inventory was used as a subjective measure for depression, and to ensure an objective measure for depression and anxiety, the Hamilton Depression and Hamilton Anxiety rating scales were implemented. Results : The positive thinking scale measured at the initial visit had shown a strong negative correlation with objective depression. Although patients with a high level of positive thinking had shown a tendency to respond better to the treatment, as compared with those with a lower level, the differences were not statistically significant. Conclusion : Positive thinking is likely to ameliorate major depressive disorder, panic disorder-induced depression, and anxiety. Nevertheless, it was not possible to confirm the effects of positive thinking on the patients' treatment responses.

• 말소리와 음성과학
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• 제8권2호
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• pp.65-71
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• 2016

The purpose of this study is to examine the prosodic pattern of the children with high functioning autism spectrum disorder(HFASD) according to sentence type. The participants were 18 children aged from 7 - 9 years; 9 children with HFASD and 9 typical development children(TD) of the same chronological age with HFASD children. Sentence reading tasks were conducted in this study. Seven interrogative sentences and 7 declarative sentences were presented to the participants and were asked to read the sentences three times. Mean values of F0, F0 range, intensity, speech rate and pitch contour were measured for each sentence. The results showed that for F0 range, significant main effect and interaction effect were observed in the subject group and sentence type. There were significant differences in intensity, mean F0, speech rate, pitch contour across sentence types. The results of this study indicated that HFASD showed no difference in intonation across sentence types. Speakers' intention may have a negative effect on pragmatic aspects. These results suggest that the assessment and intervention of prosody be important for HFASD.