• 한국유기농업학회지
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• 제12권2호
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• pp.135-151
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• 2004

U.S. organic farming has grown rapidly-20 percent or more annually-throughout the 1990s, which kept pace with consumer demand for organically produced food. Thus certified organic acreage is the total to 235 million acres in 48 state in 2001, and SO the U.S. ranked fourth in land area managed under organic farming systems. And according to several surveys, consumer's reasons for purchasing organic food are health and nutrition, taste and environmental concerns. California and North Dakota were the top two states in 2001 for certified organic cropland; the former with mostly fruits and vegetables, and the latter with wheat, soybeans, and other crops. And the top two states for certified organic pasture were Colorado and Texas. And then several states such as Iowa and Minnesota have begun subsidizing conversion to organic farming systems as a way to capture the environmental benefits of these systems. The price of organic produce fluctuates rather broadly because of being traded by market economy principle and of demand-supply disequilibrium. Nevertheless, average price premiums for organic produce are higher than the prices for the produce under conventional farming. Future prospects for U.S. organic farming are as follows; Demand for organically grown foods is expected to continue growing at a rapid pace, as more growers convert to organic production and more processors and distributors expand organic selections in their product lines. And new processed products and new types of healthy foods are likely to appear on the market, and some new organic products will be aimed at mainstream markets.

• The Korean Journal of Pain
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• 제12권1호
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• pp.140-143
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• 1999

Ramsay-Hunt syndrome is a related but more serious disorder caused by herpes zoster viral infection of the geniculate ganglion. It is characterized by unilateral painful vesicular rash of the uvula, palate, auricle, ear canal, and postauricular area, but it can extend into the facial tissues as well. Paralysis of the facial nerve is often seen, and there can be disequilibrium and hearing problems also. We experienced continuous cervical epidural block (CCEB) with intermittent stellate ganglion block is effective in Ramsay-Hunt syndrome. CCEB should be considered to the treatment of choice in Ramsay-Hunt syndrome.

• 한국해안해양공학회지
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• 제12권1호
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• pp.19-26
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• 2000

폭풍발생에 따른 해안종단방향의 표시이동은 경빈과 사구의 침식, 연안사주의 생성등 해안단면변화에 있어 주요한 요인의 하나로 알려져 있다. 그러나 폭풍발생에 따른 표사이동은 표사의 입경, 수면상승높이, 쇄파고 등 많은 요소들에 의해 복합적으로 작용하기 때문에 현재에도 정확한 예측이 어려운 실정이다. 본 논문에서는 해안단면에서의 평형에너지소산개념과 표사량 예측에 있어 주요한 요소인 표사량 파라미터를 차원해석을 통하여 변수화하고 수치모델에 도입하여 폭풍발생에 따른 해안종단방향의 해안단면변화와 해빈침식에 대하여 분석하여 보았다. 해안종단방향의 해빈침식은 단면형상 파라미터, 표사량 파라미터, 수면상승높이에 의해 크게 영향을 받음을 알 수 있다.

• 자원환경지질
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• 제31권5호
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• pp.415-424
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• 1998

In order to investigate soil-gas $^{222}Rn$ concentrations, Kwanak Campus (Seoul National University), Boeun (Choong-buk) and Gapyung (Kyonggi) areas were selected and classified depending on their base rock types. Radon risk indices of these study areas decrease in the order of Gapyung>Kwanak Campus>Boeun areas, and in the order of rock type as banded gneiss>granite gneiss>granite>black slate-shale>mica schist>shale-lirnestone>phyllite-schist. Radon emanating trends with water content and grain size of soils were assessed by modified Morse 3 min. method. Radon emanation increases with the increase of water content in soils which is lower than 6~16 wt.%, and decreases in the range of higher than 6-16 wt. %. It shows that Rn emanation increases with the decrease of soil grain size. Radioactivity analysis of radionuclides of 238U series in some soil samples shows that radioactive disequilibrium state between $^{226}Ra$ and $^{238}U$ exists owing to different geochemical behavior of each radionuclide, and, it is necessary to carry out radioactive isotope geochemical approach for soil-gas $^{222}Rn$ study.

• 한국동물번식학회:학술대회논문집
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• 한국동물번식학회 2001년도 발생공학 국제심포지움 및 학술대회 발표자료집
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• pp.14-17
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• 2001

Positional cloning (map-based cloning) of mutations or genetic variations has been served as an invaluable tool to understand in-vivo functions of genes and to identify molecular components underlying phenotypes of interest. Mice homozygous for the cerebellar deficient folia (cdf) mutation are ataxic, with cerebellar hypoplasia and abnormal lobulation of the cerebellum. In the cdf mutant cerebellum approximately 40% of Purkinje cells are ectopically located within the white matter and the inner granule cell layer (IGL). To identify the cdf gene, a high-resolution genetic map for the cdf-gene-encompassing region was constructed using 1997 F2 mice generated from C3H/HeSnJ-cdf/cdf and CAST/Ei intercross. The cdf gene showed complete linkage disequilibrium with three tightly linked markers D6Mit208, D6Mit359, and D6Mit225. A contig using YAC, BAC, and P1 clones was constructed for the cdf critical region to identify the gene. A deletion in the cdf critical region on chromosome 6 that removes approximately 150kb of DNA was identified. A gene associated with this deletion was identified using cDNA selection. cdf mutant mice with the transgenic copy of the identified gene restored the brain abnormalities of the mutant mice. The positional cloning of cdf gene provides a good example showing the identification of a gene could lead to finding a new component of important molecular pathways.

• 한국환경성돌연변이발암원학회지
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• 제22권1호
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• pp.30-38
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• 2002

In view of the effect of antithrombin III on essential hypertension, we investigated the 5' untranslated exon 1 length (I/D) polymorphism and intron 5'-DdeI RFLP of the human antithrombin III gene in the Korean patients with essential hypertension. There were no significant differences in the allele, genotype and haplotype frequencies of these polymorphisms between normotensive and essential hypertensive subjects. The significant linkage disequilibrium was however, detected between I/D polymorphism and Dde I RFLP. The I/D polymorphism was also significantly associated with BMI, total cholesterol (TC) and HDL- cholesterol levels, while DdeI polymorphism with age and BMI. Therefore, our results suggest that the significant association between the genetic polymorphisms in the antithrombin III gene and variable cardiovascular risk factors may reflect the potential role of human antithrombin III gene in cardiovascular function.

• Genomics & Informatics
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• 제12권4호
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• pp.165-170
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• 2014

Genome-wide association (GWA) studies have found many important genetic variants that affect various traits. Since these studies are useful to investigate untyped but causal variants using linkage disequilibrium (LD), it would be useful to explore the haplotypes of single-nucleotide polymorphisms (SNPs) within the same LD block of significant associations based on high-density variants from population references. Here, we tried to make a haplotype catalog affecting body mass index (BMI) through an integrative analysis of previously published whole-genome next-generation sequencing (NGS) data of 7 representative Korean individuals and previously known Korean GWA signals. We selected 435 SNPs that were significantly associated with BMI from the GWA analysis and searched 53 LD ranges nearby those SNPs. With the NGS data, the haplotypes were phased within the LDs. A total of 44 possible haplotype blocks for Korean BMI were cataloged. Although the current result constitutes little data, this study provides new insights that may help to identify important haplotypes for traits and low variants nearby significant SNPs. Furthermore, we can build a more comprehensive catalog as a larger dataset becomes available.

• 생물정신의학
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• 제16권2호
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• pp.121-126
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• 2009

Objectives : The serotonin transporter gene(SLC6A4) is one of the most widely studied candidate genes in autism spectrum disorder(ASD), but there have been conflicting results from studies into the association between SLC6A4 and ASD. The aim of this study was to evaluate the association between single nucleotide polymorphisms(SNPs) in the SLC6A4 gene and ASD in the Korean population. Methods : We selected 12 SNPs in SLC6A4 and observed the genotype of 151 Korean ASD trios. We tested the family-based association for each individual polymorphism and haplotype by using the standard TDT method in Haploview(http://www.broad.mit.edu/mpg/haploview/). Results : Through transmission-disequilibrium testing and haplotype analysis, we could not find any statistically significant transmitted allele or haplotype. In addition, a case-control association test with Korean HapMap data did not reveal any statistical significance. Conclusion : Although serotonin-related genes must be considered candidate genes for ASD, we suggest that common SNPs of SLC6A4 are not important markers for associations with Korean ASD.

• 산업경영시스템학회지
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• 제8권12호
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• pp.65-77
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• 1985

The mainpoints of General Theory is 1) the mainspring of economic activity is effective demand which can expand or control in relation to supply as a result of spontaneous decision by customer or government. 2) change in effective demand Produce change in output and employment in the same direction 3) which given productivity of labour the Vice level depend on the money supply affect the in downward direction 4) change in the money supply affect the economy through the rates of interest 5) the only automatic mechanism through which the economy can adjust itself to a deficiency of effective demand is the long process which unemployment reduces wage rates and consequently the demand for money and interest rates, above summarized contents are General Theory frame-work. The neo-classical macro general equilibrium theory, which has been reconstructed subsequent to Keyneses critism is treated the neo-classical macro-general equilibrium theory which inherits the classical theories of labour market and the aggregate production function, on demand side, it introduce the Keyneses macro-general equilibrium theory, which function through flexible movement of prices, wage and interest. Nowadays, Keynes General Theory is being developed into new dimension i, e. the macro-disequilibrium theory, and adequacy, and appropriateness of the theory and its significant contributions to modern economics are being reinterpreted and substantiated.

• Agribusiness and Information Management
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• 제12권2호
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• pp.40-54
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• 2021

Market integration and prices in pulse crops like black gram play an important role in determining the production decisions of the farmers and diversification towards high value nutritious crops. In this context, the present study explores extent of market integration and price transmission in selected major black gram markets in Andhra Pradesh using Johansen co-integration, Vector Error Correction Model and Granger causality test. The study used monthly prices data of black gram (Rs/quintal) sourced from selected markets of Srikakulam, Krishna and Kurnool spanning January, 1990 to December, 2019. The results of the study strongly buttressed the existence of co-integration and interdependence of selected black gram markets in Andhra Pradesh. However, the speed of adjustment of the prices found to be moderate in Krishna market and quite weaker in Srikakulam market and thereby prices correct a small percentage of the disequilibrium in these markets with the greatest percentage by the external and internal forces. So, it necessitates the need for future research, to investigate the influence of external and internal factors such as market infrastructure, Government policy and self-sufficient production, product characteristics and utilization towards market integration. As there exists only unidirectional causality from Krishna to Kurnool and from Krishna to Srikakulam markets, it calls for strengthening the information technology for flow of market information regularly to help the farmers for increasing their income.