• The Journal of Korean Medicine
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• v.37 no.4
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• pp.30-35
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• 2016

Objectives: The patients who had arteriosclerotic occlusive disease were treated by reperforating procedures or vessel replacing operations. We divided them by two groups. one(control group) is treated by Pletaal(cilostazole), the other(CP group) is by Pletaal with cardiotonic pills(CP). Methods : Control group was treated by Pletaal, CP group was treated by Pretaal with CP for 8 weeks. We primarily evaluated the outcomes by visual analogue scale(VAS) of pain, coldness, numbness, and edema, secondarily hematologic tests. Results : Coldness, numbness and edema were reduced at both groups. In CP group, the VAS dropped more sharply than control group, but not significant. Otherwise, there was significant reduction of VAS on pain. In hematologic tests, there were no abnormal results of all items. Conclusion : The therapy of Pletaal with CP is effective to relieve PRS specially in pain and safety on hematologic tests.

• Proceedings of the ESK Conference
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• 1996.04a
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• pp.160-167
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• 1996

The early diagnosis has an very important role in curing dementia. But there was not an effective method to diagnose it until now. In this paper we analyzed the EEG in Alzheimer's disease and normal control groups to compare by nonlinear parameter such as the largest Lyapunov exponent $L_{1}$. We found that patients with Alzheimer's disease have significantly lower$L_{1}$ than normal groups. And we propose the nonlinear analysis of EEG as a useful tool for the early diagnosis of Alzheimer's disease.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.20 no.1 s.32
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• pp.265-284
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• 2007

Introduction : There are three major forms of Epidermolysis Bullosa(EB) - EB Simplex(EBS), Junctional EB(JEB) and Dystrophic EB(DEB). DEB is divided into two groups that Dominant DEB(DDEB) and Recessive DEB(RDEB). RDEB has two types that Hallopeau-Siemens(generalized type) and mitis(localized type). Objects : This study was carried out to observe the progress of Recessive Dystrophic Epidermolysis Bullosa-mitis(RDEB-mitis) disease and find effective remedy. Methods: Both diagnosis and treatment were divided into three groups voluntarily. l. diagnosis - dermatic symptoms, mucosal symptoms, general symptoms 2. treatment - herbal medications, moxibustion, medicines used extemally(外用藥) Results : After treating 9 months, the condition of the patient grew better and the grades of severity of ROEB-mitis disease were lower at each diagnosis item. Conclusions : As above results, oriental medical treatments were very effective for this disease. But more case studies are necessary for establishing more effective diagnosis and treatment methods.

• Health Policy and Management
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• v.31 no.1
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• pp.1-4
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• 2021

With this as a momentum of approval Pfizer vaccine against coronavirus disease 2019 (COVID-2019), it is changed to the era of vaccine rapidly. Most countries are trying to reserve effective vaccines and inoculate vaccines into high-risk populations for achieving community immunity. I reviewed several vaccine-related issues to be confronted for moving up to the end of COVID-2019: the efficacy and effectiveness of the approved vaccines, the priorities for vaccination into target groups, side effects, and distrust towards COVID-2019 vaccines. Evidence-based decision-making in the policy process and collaboration with professional groups are the most effective strategies for driving successful vaccination policy.

• Journal of Korean Academy of Nursing
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• v.32 no.2
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• pp.196-205
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• 2002

The purposes of this study was to evaluate an occupational health promotion program for the prevention of cardiovascular disease. Method: This study employed a quasi-experimental non-equivalent pre and post test to evaluate the program. The subjects of this study were 48 employees selected by convenience sampling who were suspected of having hypertension and hyperlipidemia in routine physical examinations and who were working in A University Hospital in Suwon. 25 subjects were assigned to the experimental group and 23 to the control group. Data collection was done using questionnaries before and after the subjects used the program. Results: The results of this study showed that systolic blood pressure, ALT, γ-GTP in the experimental group was lower than that of the control group. There were significant differences between two groups in the percentage of 'irregularity of diet' and in health behavior compliance. There were significant differences between the two groups in the number of complaints of symptoms after using the program. Conclusion: This study shows that there were no obvious differences between the two groups in all areas, but this program had a positive effect on health behavior changes. It is expected that employees' lifestyles can be changed through continuous health promotion programs.

• Journal of Nutrition and Health
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• v.28 no.5
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• pp.451-459
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• 1995

This study was intended to figure out the effects of the amount and the distribution of body fat on the risk fators of adult disease. Sixty-four male college students paticipatied in this study, whose to find out body fat distributions were classified on the basis of Waist/hip ratio(WHR) into three groups-upper body type(UBTM), intermediate body type (IBTM) and lower body type(LBTM). Various risk factors such as adiposity, body fat ammount, serum lipid amount and blood pressure and their intercorrelations were analyzed. The three bodys type groups showed significant differences each other in weight(P<0.001), WHR showed considerable correlations with BMI and the percentage of body fat. The frequency of obesity assessed by BMI$\geq$25 and body fat percentage were the highest in the UBTM of the three groups. Thus, we could conclude that the closer the body fat distribution is to the upper body type, the higher the BMI and body fat percentage. Waist/girth ratio(WTR, P<0.01) and BMI(P<0.05) were positively correlated with serum triglyceride levels, and % of body fat was positively correlated with both serum triglyceride (P<0.01) and serum total cholesterol(P<0.05) levels. WHR (P<0.05), BMI(P<0.01) and % of body fat(P<0.01) also showed positive correlations with systolic blood pressure. From the above results, we could conclude that body fat distribution was a good index reflecting adiposity and body fat amount and that blood and serum amount of triglyceride was highest in the upper body type group showing the highest frequency of obesity.

• Korean Journal of Veterinary Research
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• v.57 no.3
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• pp.197-200
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• 2017

This study evaluated the effect of a combination of acetaminophen and vitamin C (CAV) on reducing serum cortisol and tumor necrosis $factor-{\alpha}$ ($TNF-{\alpha}$) concentrations in piglets vaccinated with foot-and-mouth disease (FMD) vaccine. Piglets were vaccinated with FMD vaccine and treated with CAV at concentrations of 0.0, 0.5, 1.0, and 2.0 kg/ton feed (P-CON, AD-1, AD-2, and AD-3, groups, respectively) for 5 days post-vaccination. Cortisol and $TNF-{\alpha}$ levels at 5 days post-treatment in the AD-1-3 groups were significantly lower than that in the P-CON group (p < 0.05). There were no significant differences between AD-2 and AD-3 groups and non-vaccinated, non-CAV-treated piglets.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.13
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• pp.5169-5173
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• 2015

To determine the efficacy of postoperative adjuvant chemotherapy with paclitaxel plus cisplatin (Taxol + DDP, TP therapy) for stage IIA esophageal squamous cell carcinoma (ESCC) and to investigate the expression of RUNX3 in lymph node metastasis-negative esophageal cancer and its relationship with medical prognosis, a retrospective summary of clinical treatment of 143 cases of stage IIA esophageal squamous cell carcinoma patients was made. The patients were divided into two groups, a surgery alone control group (52 patients) and a chemotherapy group that received postoperative TP therapy (91 patients). The disease-free and 5 year survival rates were compared between the groups and a multivariate analysis of prognostic factors was performed. The same analysis was performed for cases classified as RUNX3 positive and negative, with post-operative specimens assessed by immunohistochemistry. Although the disease-free and 5 year survival rates in control and chemotherapy groups did not significantly differ and there was no significance in RUNX3 negative cases, postoperative adjuvant chemotherapy in the chemotherapy group was shown to improve disease-free and 5 year survival rate compared to the control group in RUNX3 positive cases. On Cox regression multivariate analysis, postoperative adjuvant chemotherapy (P<0.01) was an independent prognostic factor for RUNX3 positive cases, suggesting that postoperative TP may be effective as adjuvant chemotherapy for stage IIA esophageal cancer patients with RUNX3 positive lesions.

• Korean Journal of Veterinary Research
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• v.56 no.4
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• pp.205-208
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• 2016

The aim of the present study is to investigate the potential influence of obesity as a factor in 5-hydroxytryptamine (5-HT) concentration in myxomatous mitral valve disease (MMVD) dogs. Fifty-five client-owned dogs were enrolled in a randomized trial. Dogs were classified by echocardiography into healthy (control), mild, and moderate to severe MMVD groups. Each group was subclassified by using a 9-point body condition score (BCS); lean (BCS 5-6/9) and obese groups (BCS 7.5-9/9). Dogs with moderate to severe MMVD had lower serotonin (5-HT) concentrations than the control group (p = 0.03). Dogs with moderate to severe MMVD (p = 0.017) had lower serum 5-HT concentrations than the control group in the obese group (BCS 7.5-9/9). Significant difference was found between the lean and obese groups (p = 0.015) which are not consider severe in the MMVD group. These results suggested that 5-HT concentration was decreased with the increasing severity of MMVD, and obesity might be taken into consideration when interpreting the serotonin concentration in MMVD dogs.

• Journal of Korean Medicine Rehabilitation
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• v.25 no.2
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• pp.155-173
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• 2015

Objectives The purpose of this study is to investigate the characteristics of inpatients who were admitted to Korean medicine hospital due to shoulder pain. Methods Characteristics of four hundred ten shoulder pain inpatients of single institution from 2011 to 2013 were retrospectively reviewed through medical charts. Results Patients showed different characteristics in sex, age, motives, interval between onset and admission day, first occurrence or not, related medical history before admission, usage of west medication, admission days, treatment results, radiological examinations by shoulder pain disease groups. Accordingly, Korean medical treatment such as acupuncture, moxibustion, external treatment, cupping therapy, physiotherapy, herb-medication varied with the characteristics of shoulder pain disease groups. Conclusions Through retrospective medical charts review, characteristics of 410 single institution shoulder pain inpatients showed distinctive features and versatile Korean medicine treatments by disease groups. It is expected that this study would accelerate multi-institutional and large scale characteristic review of shoulder pain patients, which would raise reconsideration and expand boundary of Korean medicine.