• The Journal of Korean Obstetrics and Gynecology
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• v.19 no.4
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• pp.61-76
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• 2006

Purpose : This study examined the non-toxic and the anti-oxidative effect of Dioscoreae Rhizoma on PC12 cells. Sanyak(Dioscoreae Rhizoma; chinese yam, shan yao) is well-known for its curing power for kidney, lung, spleen. Tonifies and augments the spleen and stomach. Tonifies the lung gi and augments the kidney yin. Tonifies the kidneys and also stabilizes and binds. it also binds the essence and treats spermatorrhea, frequent urination, and vaginal discharge. We are therefore interested in whether Dioscoreae Rhizoma is capable of causing abnormal apoptosis processes, and whether this condition can be rectified through Dioscoreae Rhizoma herb treatment. Methods : We used aqueous extract to treat PC12 cells with different concentrations treated with a water or a MeOH extract of Dioscoreae Rhizoma (0, x10, x20, x40, x80). The MTT (3, (4, 5-dimethyl-thiazol) 2, 5-diphenyl-tetraxolium bromide) reduction assay was employed to quantify the differences in cell activity and viability. The Bax expression level was monitored using western-blotting techniques. The patterns of the changes in expression were scanned and analyzed. Results : Bax and GSK-3${\beta}$ promotes cell death and down-regulated during the development of the PC12 cells. This is indicated that Dioscoreae Rhizoma is capable of inducing apoptosis in PC12 cells. The induced cell death and significantly inhibited by Dioscoreae Rhizoma, which can be explained by the increase in the inhibition of Bax and GSK-3${\beta}$ expression. It was also shown that Dioscoreae Rhizoma inhibits the release of $H_2O_2$ and prevents lipid peroxidation. Furthermore, the accumulation of wild type Bax protein significantly downregulated in a dose-dependent manner upon treatment with Dioscoreae Rhizoma. Conclusion : In conclusion, Dioscoreae Rhizoma can induce apoptosis via a Bax-dependent pathway or GSK-3${\beta}$ dependent pathway in PC12 cells into anti-oxidant and protective effect.

• Journal of the Korean Electrochemical Society
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• v.15 no.2
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• pp.95-100
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• 2012

$LiFePO_4$ is an attractive cathode material due to its low cost, good cyclability and safety. But it has low ionic conductivity and working voltage impose a limitation on its application for commercial products. In order to solve these problems, the iron($Fe^{2+}$)site in $LiFePO_4$ can be substituted with other transition metal ions such as $Mn^{2+}$ in pursuance of increase the working voltage. Also, reducing the size of electrode materials to nanometer scale can improve the power density because of a larger electrode-electrolyte contact area and shorter diffusion lengths for Li ions in crystals. Therefore, we chose electrospinning as a general method to prepare $Li[Fe_{0.9}Mn_{0.1}]PO_4$ to increase the surface area. Also, there have been very a few reports on the synthesis of cathode materials by electrospinning method for Lithium ion batteries. The morphology and nanostructure of the obtained $Li[Fe_{0.9}Mn_{0.1}]PO_4$ nanofibers were characterized using scanning electron microscopy(SEM). X-ray diffraction(XRD) measurements were also carried out in order to determine the structure of $Li[Fe_{0.9}Mn_{0.1}]PO_4$ nanofibers. Electrochemical properties of $Li[Fe_{0.9}Mn_{0.1}]PO_4$ were investigated with charge/discharge measurements, electrochemical impedance spectroscopy measurements(EIS).

• Applied Chemistry for Engineering
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• v.20 no.4
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• pp.402-406
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• 2009

$TiO_2$ thin films were surface-modified with atmospheric plasma and their photocatalytic activities were evaluated. The films were deposited on glass plates by dip-coating in a $TiO_2$ sol-gel solution and sintered at various temperatures for various times. Nitrogen plasma was used for the modification and the experiments were carried out varying operational parameters such as discharge power and treatment time. Photocatalytic activity was evaluated based on the degradation efficiency of methylene blue (MB) under irradiation of UV-A and fluorescent light. According to XPS analysis, a little amount of nitrogen was found to be doped in the film surface after the modification. As a result, photocatalytic activity increased under irradiation of UV-A and fluorescent light, especially fluorescent light.

• Journal of Korea Water Resources Association
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• v.44 no.7
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• pp.553-563
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• 2011

According to the improvement of computer's performance, the development of Geographic Information System (GIS), and the activation of offering information, a distributed model for analyzing runoff has been studied a lot in recently years. The distribution model is a theoretical and physical model computing runoff as making target basin subdivided parted. In the distributed model developed by this study, the volume of runoff at the surface flow is calculated on the basis of the parameter determined by landcover data and a two-dimensional diffusion wave equation. Most of existing runoff models compute velocity and discharge of flow by applying Manning-Strickler's mean velocity equation and Manning's roughness coefficient. Manning's roughness coefficient is not matched with dimension and ambiguous at computation; Nevertheless, it is widely used in because of its convenience for use. In order to improve those problems, this study developed the runoff model by applying not only Manning-Strickler's equation but also Chezy's mean velocity equation. Furthermore, this study introduced a power law of exponential friction factor expressed by the function of roughness height. The distributed model developed in this study is applied to 6 events of fan-shape basin, oblong shape test basin and Anseongcheon basin as real field conditions. As a result the model is found to be excellent in comparison with the exiting runoff models using for practical engineering application.

• Journal of Korean Society of Environmental Engineers
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• v.39 no.8
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• pp.478-488
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• 2017

Stormwater filtration is widely used for the urban runoff treatment. However, intensive maintenance and lack of information about the performance have resulted in an increased need of proper evaluation. In this study, the performance of an upflow stormwater runoff filtration system, consisting of a supporting unit and a filtration unit filled with a ceramic media, was investigated. The maximum head loss increase was about 3 cm under the suspended solid (SS) load of $30kg/m^2$ and the SS removal was more than 96%, when the filtration velocity was 20-40 m/h. The head loss and the porosity of the media can successfully be described by a power model. It was confirmed that the a significant amount of SS can effectively be removed at supporting unit, minimizing SS load to the filter media bed. Several backwashing strategies have been tested to establish the optimum condition. It was found that the stagnant water discharge is important to minimize the SS release immediately after backwashing. Also, the filter bed loaded with $400-450kg/m^2$ SS can almost completely be washed to reduce the head loss to the that of empty bed. The results in this study indicate that the upflow ceramic media filter is an excellent alternative to stormwater treatment, with high SS removal and long lifespan.

• Journal of Navigation and Port Research
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• v.28 no.10 s.96
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• pp.947-953
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• 2004

As a large scale port development in coastal waters proceeds step by step and populations in the vicinity of port are getting increased, the issue on 'how to dispose the treated municipal water and wastewater in harbor' brings peoples' concern. The submarine outfall system discharges the primary or secondary treated effluent at the coastline or in deep water, or between these two. The effluent, which has a density similar to that of fresh water, rises to the sea surface forming plume or jet, together with entraining the surrounding sea water and becomes very dilute. We intended in this paper to investigate the impact on dilution of effluent and the behavior of flume under the conditions of the seasonal and spatial temperature variations, which have not been noticeable in designing effective marine outfall system. To predict and analyze the behaviour and dilution characteristics of plume not just with the effluent temperature, but also with the seasonal variation of temperature of surround water, CORMIX( Cornell Mixing Zone Expert System)-GI have been applied. The results should be used with caution in evaluation the mixing zone characteristics of discharged water. We hope to help for the effective operation of outfall system, probable outfall design, protection of water quality, and warm water discharges from a power plant, etc.

• Journal of Korea Water Resources Association
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• v.48 no.8
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• pp.605-612
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• 2015

The purpose of this study is to compare and analyze design flood estimation methods which are the basis for determining the size of a flood control structure. The result from a flood frequency analysis which is considered as the best way for estimating design flood was assumed as a true value, and a method of simulating runoff and performing frequency analysis of the maximum discharge data were compared with a design storm method. For a comparative analysis of design flood estimation, seven basins (Namgang reservoir basin, Soyanggang reservoir basin, Andong reservoir basin, Seomjingang reservoir basin, Imha reservoir basin, Chungju reservoir basin, Hapcheon reservoir basin) were selected. For the Seomjingang, Hapcheon, and Imha reservoir basins, the method proposed in this study showed better results, whereas the conventional method showed better results for the Namgang, Soyanggang, and Chungju reservoir basins. The results show that the conventional method (the design storm method) is not the best way for estimating design flood and the proposed method can be used as an alternative for small basins.

• Journal of Environmental Policy
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• v.11 no.4
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• pp.85-105
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• 2012

In this paper, the energy efficiency of wastewater utilities was evaluated to explore ways to save energy via operational measures. The correlation of each wastewater characteristic parameter to energy was assessed to find a set of parameters that explained most of the variations in energy use among utilities. The results show that increases in inflow, influent COD concentration, and ratio of advanced treatment generally increased the energy use. On the other hand, increases in load factor (influentaverage flow/design flow) reduced the energy use. In the regression analysis, the energy efficiency was highest in the A2O advanced process. On the other hand, the membrane process (among the advanced processes) and the contacted aeration process (among the secondary processes) require more efforts in saving energy. However, the data base system related to energy use must be supplemented in order for more accurate analysis of energy consumption in wastewater treatment facilities. In particular, i) electricity consumption of relay pumps and, ii) energy usage per unit process, iii) pump power usage to discharge treated wastewater in a long distance, if necessary, and iv) alternative energy production and utilization status must be recorded. By utilizing the results of the analysis conducted in this study, it is possible to quantify a level of energy savings needed and establish customized energy saving measures to achieve a certain target level for benchmarking a successful case of wastewater utilities.

• Journal of the Korean Electrochemical Society
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• v.9 no.1
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• pp.1-5
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• 2006

Lithium titanium oxide $(Li_4Ti_5O_{12})$ with spinel-framework structures as anode material for lithium-ion battery was prepared by sol-gel and high energy ball milling (HEBH) method. According to the X-ray diffraction (XRD), Particle Size Analyses(PSA) and scanning electron microscopy (SEM) analysis, uniformly distributed $Li_4Ti_5O_{12}$ particles with grain sizes of 100 nm were observed. Half cells, consisting of $Li_4Ti_5O_{12}$ as working electrode and lithium foil as both counter and reference electrodes showed the high performance of high rate discharge capacity and 173 mAh/g at 0.2C in the range of $1.0\sim2.5 V$. Furthermore, the crystalline structure of $Li_4Ti_5O_{12}$ didn't transform during the lithium intercalation and deintercalation process.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.46 no.12
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• pp.105-112
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• 2009

In this paper, we investigated abnormal ESD failure on guard-rings in the smart power IC fabricated with $0.35{\mu}m$ Bipolar-CMOS-DMOS (BCD) technology. Initially, ESD failure occurred below 200 V in the Machine Model (MM) test due to current crowding in the parasitic diode associated with the guard-rings which are generally adopted to prevent latch-up in high voltage devices. Optical Beam Induced Resistance Charge (OBIRCH) and Scanning Electronic Microscope (SEM) were used to find the failure spot and 3-D TCAD was used to verify cause of failure. According to the simulation results, excessive current flows at the comer of the guard-ring isolated by Local Oxidation of Silicon (LOCOS) in the ESD event. Eventually, the ESD failure occurs at that comer of the guard-ring. The modified comer design of the guard-ring is proposed to resolve such ESD failure. The test chips designed by the proposed modification passed MM test over 200 V. Analyzing the test chips statistically, ESD immunity was increased over 20 % in MM mode test. In order to avoid such ESD failure, the automatic method to check the weak point in the guard-ring is also proposed by modifying the Design Rule Check (DRC) used in BCD technology. This DRC was used to check other similar products and 24 errors were found. After correcting the errors, the measured ESD level fulfilled the general industry specification such as HBM 2000 V and MM 200V.