• Journal of Preventive Medicine and Public Health
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• 제34권3호
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• pp.277-283
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• 2001

Objectives : To investigate the prevalence of hazardous and harmful alcohol use, which are a subthreshold of alcohol related disorders, Methods : Direct-interview questionnaires to 1,183 rural persons (489 male, 694 female) were conducted in Chungju-city from July 2 to 20, 1998. As a screening instrument, the alcohol use disorders identification test (AUDIT) was used. Results : The prevalence of alcohol use was 41.7%. In males, it was 66.3% and in females, it was 24.4%. The mean of the AUDIT score of males and females was 13.2 and 5.6, respectively. As WHO guideline, the prevalence of hazardous alcohol use in males and females was 80.3% and 20.7%, respectively. This suggests that the prevalence of 'hazardous drinking' and 'harmful drinking' was 45.4% and 29.3% for males and 1.2% and 2.4% for females, respectively. Conclusions : This study presented the prevalence of hazardous and harmful drinking of a rural population in Korea and reviewed those health problems. Further evaluation to detect and treat lower alcoholic drinkers is recommended.

• 한국자동차공학회논문집
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• 제8권6호
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• pp.142-155
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• 2000

A MIMO model reference control scheme incorporating the variable structure theory for a vehicle four wheel steering system(4WS) is proposed and evaluated for a class of continuous-time nonlinear dynamics with known or unknown uncertainties. The scheme employs an neural network to identify the plant systems, where the neural network estimates the nonlinear dynamics of the plant. By the Lyapunov direct method, the algorithm is proven to be globally stable, with tracking errors converging to the neighborhood of zero. The merits of this scheme is that the global system stability is guaranteed and it is not necessary to know the exact structure of the system. With the resulting identification model which contains the neural networks, it does not need higher degrees of freedom vehicle model than 3 degree of freedom model. Th proposed scheme is applied to the active four wheel system and shows the validity is used to investigate vehicle handing performances. In simulation of the J-turn maneuver, the reduction of yaw rate overshoot of a typical mid-size car improved by 30% compared to a two wheel steering system(2WS) case, resulting that the proposed scheme gives faster yaw rate response and smaller side angle than the 2WS case.

• International Journal of Control, Automation, and Systems
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• 제5권5호
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• pp.559-569
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• 2007

In this paper, the dynamic controller design problem of a redundant planar 2-dof parallel manipulator is studied. Using the Euler-Lagrange equation, we formulate the dynamic model of the parallel manipulator in the joint space and propose an augmented PD controller with forward dynamic compensation for the parallel manipulator. By formulating the controller in the joint space, we eliminate the complex computation of the Jacobian matrix of joint angles with end-effector coordinate. So with less computation, our controller is easier to implement, and a shorter sampling period can be achieved, which makes the controller more suitable for high-speed motion control. Furthermore, with the combination of static friction model and viscous friction model, the active joint friction of the parallel manipulator is studied and compensated in the controller. Based on the dynamic parameters of the parallel manipulator evaluated by direct measurement and identification, motion control experiments are implemented. With the experiments, the validity of the dynamic model is proved and the performance of the controller is evaluated. Experiment results show that, with forward dynamic compensation, the augmented PD controller can improve the tracking performance of the parallel manipulator over the simple PD controller.

• 간호행정학회지
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• 제11권4호
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• pp.371-384
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• 2005

Purpose: The aim of this study was to analysis path model of the research variables. Methods: The subjects of this study were 647 nurses who were working in the 8 general hospitals located in Seoul and Incheon area. The data were collected by self-reporting questionnaires. The data were analyzed using descriptive statistics and path analysis. Results: In the modified path model, overall fitness indexes were $X^2$= 223.27, goodness of fit index=0.90, root mean square residual=0.039, root mean square error of approximation=0.12, non-normed fit index=0.96, and normed fit index=0.90. From the model, among research variables that influence organizational effectiveness motivator, job satisfaction and organizational identification affected directly work performance. In internal marketing factors, paid-leave, communication and reward affected directly motivator. Motivator and hygiene factors affected directly job satisfaction, organizational commitment and organizational identification. Conclusion: With these findings, paid-leave, communication, reward, motivator, job satisfaction and organizational identification were direct or indirect predictors of the work performance. Therefore nursing managers ought to develop internal marketing strategies and motivation enhancing system for nurses based on this path model in order to improve the nursing organizational effectiveness.

• Mycobiology
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• 제31권4호
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• pp.196-199
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• 2003

A very reliable and specific method for the identification of fungi in ectotrophic mycorrhizal symbiosis was developed using a specific PCR assay based on the amplification of the ITS1 region. To obtain specific data, an ITS-diagnostic assay was carried out that reveals genera and species specific sequences. Here, an application of one method is presented, which covers the identification of pure mycelia, basidiocarps as well as mixed samples such as ectomycorrhizal roots that were mingled with remains of the host plant. For this purpose a protocol was established that allowed the extraction of DNA from single mycorrhizal roots. In order to perform a specific ITS analysis we generated a new ITS-primer(ITS8) by a multiple alignment of five different genera and species of mycorrhizal fungi. The utilization of ITS1 and ITS8 resulted in specific PCR amplicons, which were characterized by sequencing without purification steps, even when the template DNA was associated with roots.

• 한국산업정보학회논문지
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• 제7권1호
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• pp.10-15
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• 2002

시스템 외란과 계측 외란이 겹친 플랜트의 시스템과 외란 인식기술의 확장성을 소개하고자 한다. 시스템의 수의 상한영역과 외란주파수의 상한영역내에서 외란제거 모형과 외란효과가 외란이 겹친 입출력자료로부터 정기적인 외란의 직접적인 측정없이 정확히 회복될 수 있음을 보여 주고 있다. 시스템 및 외란 인식으로 계산되어 활용되는 자료: 성능관점의 모형 기저 반복학습제어시스템에 사용할 수 있게 된다. 이는 원치 않는 정기적인 외란을 제거하기 위함이다. 반복학습제어와 시스템 및 외란인식기술을 응용하면 복합구조물의 정밀도 품질보증 확보에 큰 기여를 하게 된다.

• Wind and Structures
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• 제36권1호
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• pp.61-73
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• 2023

In this article, a novel structural modal parameters identification methodology is developed to determine the natural frequencies and damping ratios of civil structures based on the symplectic geometry mode decomposition (SGMD) approach. The SGMD approach is a new decomposition algorithm that can decompose the complex response signals with better decomposition performance and robustness. The novel method firstly decomposes the measured structural vibration response signals into individual mode components using the SGMD approach. The natural excitation technique (NExT) method is then used to obtain the free vibration response of each individual mode component. Finally, modal natural frequencies and damping ratios are identified using the direct interpolating (DI) method and a curve fitting function. The effectiveness of the proposed method is demonstrated based on numerical simulation and field measurement. The structural modal parameters are identified utilizing the simulated non-stationary responses of a frame structure and the field measured non-stationary responses of a supertall building during a typhoon. The results demonstrate that the developed method can identify the natural frequencies and damping ratios of civil structures efficiently and accurately.

• Journal of Microbiology and Biotechnology
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• 제34권3호
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• pp.681-688
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• 2024

The accurate and rapid detection of methicillin-resistance of Staphylococcus aureus (SA) holds significant clinical importance. However, the methicillin-resistance detection strategies commonly require complicated cell lysis and gene extraction. Herein, we devised a novel colorimetric approach for the sensitive and accurate identification of methicillin-resistance of SA by combining allosteric probe-based target recognition with self-primer elongation-based target recycling. The PBP2a aptamer in the allosteric probe successfully identified the target MRSA, leading to the initiation of self-primer elongation based-cascade signal amplification. The peroxidase-like hemin/G-quadruplex undergo an isothermal autonomous process that effectively catalyzes the oxidation of ABTS2- and produces a distinct blue color, enabling the visual identification of MRSA at low concentrations. The method offers a shorter duration for bacteria cultivation compared to traditional susceptibility testing methods, as well as simplified manual procedures for gene analysis. The overall amplification time for this test is 60 min, and it has a detection limit of 3 CFU/ml. In addition, the approach has exceptional selectivity and reproducibility, demonstrating commendable performance when tested with real samples. Due to its advantages, this colorimetric assay exhibits considerable potential for integration into a sensor kit, thereby offering a viable and convenient alternative for the prompt and on-site detection of MRSA in patients with skin and soft tissue infections.

• Journal of Ginseng Research
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• 제33권1호
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• pp.55-58
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• 2009

Generally, the direct sequencing through PCR is faster, easier, cheaper, and more practical than clone sequencing. Frequently, standard PCR amplification is usually interpreted by mispriming internal or external regions of the target template. Normally, DNA fragments were eluted from the gel using Gel extraction kit and subjected to direct sequencing or cloning sequencing. Cloning sequencing has often troublesome and needs more time to analyze for many samples. Since touchdown (TD) PCR can generate sufficient and highly specific amplification, it reduces unwanted amplicon generation. Accordingly, TD PCR is a good method for direct sequencing due to amplifying wanted fragment. In plants the 5S-rRNA gene is separated by simple spacers. The 5S-rRNA gene sequence is very well-conserved between plant species while the spacer is species-specific. Therefore, the sequence has been used for phylogenetic studies and species identification. But frequent occurrences of spurious bands caused by complex genomes are encountered in the product spectrum of standard PCR amplification. In conclusion, the TD PCR method can be applied easily to amplify main 5S-rRNA and direct sequencing of panax ginseng cultivars.

• Asian Pacific Journal of Cancer Prevention
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• 제17권6호
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• pp.3007-3013
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• 2016

Background: Gastrointestinal cancers are common malignancies associated with high mortality rates. Healthcare systems are always faced with high costs of treatment of gastrointestinal cancers including stomach cancer. Identification and prioritization of these costs can help determine economic burden and then improve of health planning by policy-makers. This study was performed in 2015 in Kerman City aimed at estimating the direct hospital costs for patients with gastric cancer. Materials and Methods: In this cross-sectional study, the medical records of 160 patients with stomach cancer admitted from 2011 to 2014 to Shafa Hospital were examined, the current stage of the disease and the patients' health status were identified, and the direct costs related to the type of treatment in the public and private sectors were calculated. SPSS-19 was used for statistical analysis of the data. Results: Of the patients studied, 103 (65%) were men and 57 (35%) were women. The mean age of patients was 65 years. Distribution into four stages of the disease was 5%, 20%, 30%, and 45%, respectively. Direct costs in four stages of the disease were calculated as 2191.07, 2642.93, 2877, and 2674.07 USD (63,045,879, 76,047,934, 82,783,019, and 76,943,800 IRR), respectively. The highest percentage of costs was related to surgery in Stage I and to medication in Stages II, III, and IV. According to the results of direct costs of treatment for stomach cancer in Kerman, the mean total cost of treating a patient in the public sector was estimated at 74,705,158 IRR, of which averages of 60,141,384 IRR and 14,563,774 IRR were the shares of insurance and patients, respectively. Conclusions: The high prevalence and diagnosis of disease in old age and at advanced stages of disease impose great costs on the patients and the health system. Early diagnosis through screening and selecting an appropriate treatment method might largely ameliorate the economic burden of the disease.