• Structural Engineering and Mechanics
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• v.14 no.5
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• pp.595-610
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• 2002

This paper presents an efficiency of various non-conforming (NC) modes in development of a series of new finite elements with the special emphasis on 4-node quadrilateral elements. The NC modes have been used as a key scheme to improve the behaviors of various types of new finite elements, i.e., Mindlin plate bending elements, membrane elements with drilling degrees of freedom, flat shell elements. The NC modes are classified into three groups according to the 'correction constants' of 'Direct Modification Method'. The first group is 'basic NC modes', which have been widely used by a number of researchers in the finite element communities. The basic NC modes are effective to improve the behaviors of regular shaped elements. The second group is 'hierarchical NC modes' which improve the behaviors of distorted elements effectively. The last group is 'higher order NC modes' which improve the behaviors of plate-bending elements. When the basic NC modes are combined with hierarchical or higher order NC modes, the elements become insensitive to mesh distortions. When the membrane component of a flat shell has 'hierarchical NC modes', the membrane locking can be suppressed. A number of numerical tests are carried out to show the positive effect of aforementioned various NC modes incorporated into various types of finite elements.

• Applied Chemistry for Engineering
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• v.21 no.4
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• pp.475-478
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• 2010

Fluorinated polymeric membranes were prepared by direct surface modification of PDMS with fluorine gas ($50{\sim}2000\;{\mu}mol/mol$ in nitrogen). The formed fluorinated polymeric membranes were characterized by FT-IR spectroscopy, GC (Gas chromatography), atomic force microscopy, and scanning electron microscopy. Direct fluorination resulted in the change of permeability and selectivity of various gases (pure gases such as $CO_2$, $O_2$, $N_2$, $C_2H_4$, mixture of He, Ne, Kr, Xe) through PDMS membranes. Fluorination resulted in the maximum 50% increase of selectivity through PDMS membrane.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.28 no.11
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• pp.1289-1301
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• 2004

Direct numerical simulation (DNS) of strongly-heated air flows moving upward in a vertical tube has been conducted to investigate the effect of gas property variations on turbulence modification. Three heating conditions(q$_1$$^{+}$=0.0045, 0.0035 and 0.0018) are selected to reflect the experiment of Shehata and McEligot (1998) at the inlet bulk Reynolds numbers of 4300 and 6000. At these conditions, the flow inside the heated tube remains turbululent or undergoes a transition to subturbulent or laminarizing flow. Consequently, a significant impairment of heat transfer occurs due to the reduction of flow turbulence. The predictions of integral parameters and mean profiles such as velocity and temperature distributions are in excellent agreement with the experiment. The computed turbulence data indicate that a reduction of flow turbulence occurs mainly due to strong flow acceleration effects for strongly-heated internal gas flows. Thus, buoyancy influences are secondary but not negligible especially for turbulent flow at low heating condition. Digital flow visualization also shows that vortical structures rapidly decay as the heating increases.s.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2001.11a
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• pp.409-412
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• 2001

Identification of systems operating in closed loop has long been of prime interest in industrial applications. The fundamental problem with closed-loop data is the correlation between the unmeasurable noise and the input. This is the reason why several methods that work in open loop fail when applied to closed-loop data. The prediction error based approaches to the closed-loop system are divided to direct method and indirect method. Both of direct and indirect methods are known to be applied to the closed-loop data without critical modification. But the direct method induces the bias error in the experimental frequency response function and this bias error may deteriorates the parameter estimation performance

• Journal of Ocean Engineering and Technology
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• v.25 no.4
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• pp.36-41
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• 2011

In the present paper, a direct forcing/fictitious domain (DF/FD) level set method is proposed to simulate the FSI (fluid-solid interaction) in two-phase flow. The main idea is to combine the direct-forcing/fictitious domain (DF/FD) method with the level set method in the Cartesian coordinates. The DF/FD method is a non-Lagrange-multiplier version of a distributed Lagrange multiplier/fictitious domain (DLM/FD) method. This method does not sacrifice the accuracy and robustness by employing a discrete ${\delta}$ (Dirac delta) function to transfer quantities between the Eulerian nodes and Lagrangian points explicitly as the immersed boundary method. The advantages of this approach are the simple concept, easy implementation, and utilization of the original governing equation without modification. Simulations of various water-entry problems have been conducted to validate the capability and accuracy of the present method in solving the FSI in two-phase flow. Consequently, the present results are found to be in good agreement with those of previous studies.

• Journal of Microbiology and Biotechnology
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• v.9 no.1
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• pp.1-8
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• 1999

Most carbohydrates exist in nature in an insoluble state, which reduces their susceptibility towards various carbohydrases. Accordingly, they require intensive pretreatment for structural modification to enhance an enzyme reaction. The direct conversion of insoluble carbohydrates has distinct advantages for special types of reaction, especially exo-type carbohydrase; however, its application is limited due to structural constraints. This paper introduces two novel heterogeneous enzyme reaction systems for direct conversion of insoluble carbohydrates; one is an attrition coupled enzyme reaction system containing attrition-milling media for enhancing the enzyme reaction, and the other is a heterogeneous enzyme reaction system using extruded starch as an insoluble substrate. The direct conversion of typically insoluble carbohydrates, including cellulose, starch, and chitin with their corresponding carbohydrases, including cellulase, amylase, chitinase, and cyclodextrin glucanotransferase, was carried out using two proposed enzyme reaction systems. The conceptual features of the systems, their reaction characteristics and mechanism, and the industrial applications of the various carbohydrates are analyzed in this review.

• Korean Journal of Food Science and Technology
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• v.22 no.5
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• pp.562-568
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• 1990

The modified direct GLC method was evaluated for analysis of volatile compounds associated with WOF of cooked meat. This modified method was pertaining to collection of volatiles from the samples that contain quantities of water. The modification was appropriate for the studies of low molecular weight saturated aldehydes (C5-C15), unsaturated aldehydes (C5-C9), and saturated alcohols (C5-C9).

• Journal of the Korean Recycled Construction Resources Institute
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• v.8 no.2
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• pp.175-182
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• 2020

The application of epoxy coated reinforcements is increased as a means to prevent a corrosion of reinforcements embedded in reinforced concrete structures, However, epoxy coating may reduce the bond capacity between concrete and reinforcement, which results a longer development length and lap splice length. This paper aims to the possibility of modification in lap splice length from reduction of basic development length which was confirmed using a direct pull out test. Total 36 beam specimens were tested to compare the lap splice properties of normal and epoxy coated reinforcements with beam-end test for various lap lengths and diameters of reinforcements. According to the results on failure modes, deformations, and crack widths of this experiments, the modification factor of 1.2 should be used, though the direct bond capacity is assured through direct pull out test.

• The Korean Journal of Physiology and Pharmacology
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• v.24 no.6
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• pp.463-472
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• 2020

Direct reprogramming, also known as a trans-differentiation, is a technique to allow mature cells to be converted into other types of cells without inducing a pluripotent stage. It has been suggested as a major strategy to acquire the desired type of cells in cell-based therapies to repair damaged tissues. Studies related to switching the fate of cells through epigenetic modification have been progressing and they can bypass safety issues raised by the virus-based transfection methods. In this study, a protocol was established to directly convert fully differentiated fibroblasts into diverse mesenchymal-lineage cells, such as osteoblasts, adipocytes, chondrocytes, and ectodermal cells, including neurons, by means of DNA demethylation, immediately followed by culturing in various differentiating media. First, 24 h exposure of 5-azacytidine (5-aza-CN), a well-characterized DNA methyl transferase inhibitor, to NIH-3T3 murine fibroblast cells induced the expression of stem-cell markers, that is, increasing cell plasticity. Next, 5-aza-CN treated fibroblasts were cultured in osteogenic, adipogenic, chondrogenic, and neurogenic media with or without bone morphogenetic protein 2 for a designated period. Differentiation of each desired type of cell was verified by quantitative reverse transcriptase-polymerase chain reaction/western blot assays for appropriate marker expression and by various staining methods, such as alkaline phosphatase/alizarin red S/oil red O/alcian blue. These proposed procedures allowed easier acquisition of the desired cells without any transgenic modification, using direct reprogramming technology, and thus may help make it more available in the clinical fields of regenerative medicine.

• Journal of KIISE:Computer Systems and Theory
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• v.33 no.4
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• pp.205-215
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• 2006

Pen-input displays, such as LCD tablets and tablet PCs, are already popular for its usability in CAD design, in particular. in concept design phase. We propose an intuitive B-Spline modification scheme that can be used for the CAD systems targeting for such devices. Differently from the control point based modification schemes for the B-splines, our scheme relates user pen marking to determining the final shape of the target curve and surface. This, eventually, reduces time for interacting with the shape parameters (i.e., by control points or direct manipulators), which has been regarded as an unavoidable routine tasks for design. To prove its usability, we made an experiments with selected subjects who have been working for industrial design.