• Korean Journal of Acupuncture
• /
• v.38 no.3
• /
• pp.189-195
• /
• 2021

Foot drop due to lumbar disc herniation is perceived to be an indication for surgery. A 44-year-old male presented with motor deficit in left ankle dorsiflexion along with radiating pain and paraesthesia. Motion Style Acupuncture Therapy (MSAT) was administered on the left side every other day. Acupuncture and Chuna were performed daily. Herbal medicine was taken 3 times a day. His symptoms rapidly improved throughout treatment, verified by decreased Numeric Rating Scale (NRS), Oswestry Disability Index (ODI), increased 5-level EuroQol-5 Dimension (EQ-5D-5L) scores, and improved motor grades. We suggest that a combination of MSAT with traditional Korean medicine could be a favorable option for foot drop in LDH patients in terms of rapid pain reduction and the improvement of quality of life.

• Communications for Statistical Applications and Methods
• /
• v.27 no.6
• /
• pp.603-624
• /
• 2020

There is an emerging interest in brain functional connectivity (FC) based on functional Magnetic Resonance Imaging in Alzheimer's disease (AD) studies. The complex and high-dimensional structure of FC makes it challenging to explore the association between altered connectivity and AD susceptibility. We develop a pipeline to refine FC as proper covariates in a penalized logistic regression model and classify normal and AD susceptible groups. Three different quantification methods are proposed for FC refinement. One of the methods is dimension reduction based on common component analysis (CCA), which is employed to address the limitations of the other methods. We applied the proposed pipeline to the Alzheimer's Disease Neuroimaging Initiative (ADNI) data and deduced pathogenic FC biomarkers associated with AD susceptibility. The refined FC biomarkers were related to brain regions for cognition, stimuli processing, and sensorimotor skills. We also demonstrated that a model using CCA performed better than others in terms of classification performance and goodness-of-fit.

• Journal of the Korean Society of Industry Convergence
• /
• v.25 no.3
• /
• pp.357-363
• /
• 2022

In this study, in order to develop an non-slip metal grating, the stability of the grating according to the span of the grating and the gap and height of the bearing bar was evaluated. The optimal shape design of the grating was performed using the results of determining the stability of the grating. The purpose of this study is to determine the stability according to the spacing and height of the bearing bar by applying the design pressure at the design stage to develop the anti-skid grating, and to design the optimal shape for cost reduction. In the optimal design, the target variable was set as the mass, and the optimal design of the grating was performed based on about 20%. Regardless of the height of the bearing bar of the grating, the stress and deformation of the span and the grating showed a proportional tendency to each other, and it was found that the stress decreased as the height of the bearing bar increased. Based on the structural analysis results, an optimal design was performed using mass as the objective variable, and the existing 2mm thickness was changed to 1.6mm, reducing the mass by about 19%. The stress increased by about 4.4% compared to the maximum stress of the existing grating, but the minimum safety factor was 3.1, indicating that the optimally designed grating was stable.

• Journal of Acupuncture Research
• /
• v.39 no.3
• /
• pp.234-238
• /
• 2022

A 53-year-old male who had received surgery on his right ankle joint 10 years previously was diagnosed with Complex Regional Pain Syndrome the following year. Despite various treatments (sympathetic nerve-block medication, pain relievers, corticosteroids, nerve blocks, and transcutaneous electrical nerve stimulation) over the years there was no improvement in his symptoms. Recently the patient was admitted to a Korean medicine hospital where he received treatment (acupuncture, pharmacopuncture, and herbal treatment) and his symptoms gradually showed improvement. The patient was concurrently on psychiatric medicine, antihistamine medication, and opioids for pain (when necessary). A decrease in numeric rating scale, Oswestry disability index scores, and an increase in the Korean version of the 5-level EuroQol-5 dimension score showed symptom improvement within 36 days. This study suggests complex Korean medicine treatment for Complex Regional Pain Syndrome may result in a reduction in pain and improved quality of life.

• Journal of the Korean Society of Manufacturing Process Engineers
• /
• v.21 no.3
• /
• pp.77-85
• /
• 2022

In this study, to diagnose the grinding state of a micro drill bit, a sensor attachment location was selected through random vibration analysis of the grinding unit of the micro drill-bit grinding system. In addition, the vibration data generated during the drill bit grinding were collected from the grinding unit for the grinding wheels under the steady and worn conditions, and data feature extraction and dimension reduction were performed. The wear of the micro-drill-bit grinding wheel was diagnosed by applying KNN, a machine-learning algorithm. The classification model showed excellent performance, with an accuracy of 99.2%. The precision, recall and f1-score were higher than 99% in both the steady and wear conditions.

• International Journal of Computer Science & Network Security
• /
• v.22 no.12
• /
• pp.125-131
• /
• 2022

The diversity and complexity of criminal, administrative and civil cases resolved by the courts makes it difficult to develop universal automated tools for the analysis and evaluation of justice. However, big data generated in the scope of justice gives hope that this problem will be resolved as soon as possible. The big data applying makes it possible to identify typical options for resolving cases, form detailed rules for the individualization of a court decision, and correlate these rules with an abstract provisions of law. This approach allows us to somewhat overcome the contradiction between the abstract and the concrete in law, to automate the analysis of justice and to model e-justice for scientific and practical purposes. The article presents the results of using dimension reduction, SHAP value, and p-value to identify, analyze and evaluate the individualization of justice and the differentiation of legal regulation. Processing and analysis of arrays of court decisions by computational methods make it possible to identify the typical views of courts on questions of fact and questions of law. This knowledge, obtained automatically, is promising for the scientific study of justice issues, the improvement of the prescriptions of the law and the probabilistic prediction of a court decision with a known set of facts.

• The Korean Journal of Applied Statistics
• /
• v.36 no.2
• /
• pp.167-173
• /
• 2023

This paper investigates several methods of visualizing high-dimensional data in a low-dimensional space. At first, principal component analysis and multidimensional scaling are briefly introduced as linear approaches, and then kernel principal component analysis, self-organizing map, locally linear embedding, Isomap, Laplacian Eigenmaps, and local multidimensional scaling are introduced as nonlinear approaches. In particular, t-SNE, which is widely used but relatively unfamiliar in the field of statistics, is described in more detail. We also present a simple example for several methods, including t-SNE. Finally, we provide a review of several recent studies pointing out the limitations of t-SNE and discuss the future research problems presented.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
• /
• v.49 no.3
• /
• pp.107-113
• /
• 2023

Bimaxillary transverse width discrepancies are commonly encountered among patients with dentofacial deformities. Skeletal discrepancies should be diagnosed and managed appropriately with possible surgical corrections. Transverse width deficiencies can present in varieties of combinations involving the maxilla and mandible. We observed that in a significant proportion of cases, the maxilla is normal, and the mandible showed deficiency in the transverse dimension after pre-surgical orthodontics. We designed novel osteotomy techniques to enhance mandibular transverse width correction, as well as simultaneous genioplasty. Chin repositioning along any plane is applicable concomitant with mandibular midline arch widening. When there is a requirement for larger widening, gonial angle reduction may be necessary. This technical note focuses on key points in management of patients with transversely deficient mandible and the factors affecting the outcome and stability. Further research on the maximum amount of stable widening will be conducted. We believe that developing evidence-based additional modifications to existing conventional surgical procedures can aid precise correction of complex dentofacial deformities.

• Proceedings of the Korean Society of Computer Information Conference
• /
• 2022.07a
• /
• pp.61-62
• /
• 2022

알츠하이머성 치매는 현존하는 치료법이 없어 경도인지장애 단계에서의 예방이 중요하다. 지금까지의 알츠하이머 연구는 대부분이 뇌영상 마커와 뇌척수액 마커에 집중되어 있었으며, 경도 인지 장애 단계에서의 탐색은 더욱 적었다. 이러한 점에서 혈액 유전자 발현을 이용한 경도 인지장애 단계 예측은 인지 능력에 따른 관련 유전자 식별과 접근 가능한 진단 및 치료 바이오 마커 탐색에 기여할 수 있다. 그러나 유전자 발현 데이터의 경우 환자 수에 비해 높은 차원을 가지기 때문에 과적합을 막고 질병 관련 유전자를 식별하기 위해서는 데이터에서의 의미 있는 차원만을 뽑아내는 차원 축소가 선행되야 한다. 본 연구는 유전자 발현데이터에서의 인지장애 분류를 위해 차원 축소기법과 신경망을 적용하여 인지 장애 정도를 예측하였다. 그 결과, Lasso 이용 차원축소와 신경망을 이용하여 97%의 정확도로 정상과 조기 경도 인지장애, 후기 경도 인지장애 환자를 분류 할 수 있었으며, 더 적은 차원에서도 분류가 가능했다. 이는 혈액 유전자 발현을 이용해 경도 인지장애 단계를 예측한 첫 번째 연구이며, 인지능력 저하에 따른 혈액 유전자 발현의 연관성을 확인하고 향후 조기 진단, 치료 표적 탐색에 기여한다.

• Journal of Korean Medicine Rehabilitation
• /
• v.34 no.2
• /
• pp.173-180
• /
• 2024

Objectives The purpose of this study is to report the effects of Korean medicine treatment on tibia, fibula, and patellar fractures with sequelae of poliomyelitis. Methods A 64-year-old male patient was treated with acupuncture, herbal medicine, cupping, moxibustion, and exercise treatment for 59 days after open reduction and internal fixation and tension band wiring surgery. The effects were evaluated using a visual analog scale (VAS), manual muscle testing (MMT), range of motion (ROM), Western Ontario and McMaster Universities (WOMAC), and EuroQol-5 dimension (EQ-5D) index. Results After treatment, VAS decreased from 7 to 2. MMT, ROM, WOMAC, EQ-5D and walking ability were improved. Conclusions This case study suggests that Korean medicine treatment could be effective for tibia, fibula, patellar fractures in patients with sequelae of poliomyelitis.