• 제목/요약/키워드: Digital scan

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Feasibility of Reflecting Improvement of Tumor Hypoxia by Mild Hyperthermia in Experimental Mouse Tumors with $^18F-Fluoromisonidazole$ (저온온열치료에 의한 종양 내 저산소상태 개선효과를 $^18F$-Fluoromisonidazole의 섭취 변화를 이용한 평가)

  • Lee Sang-wook;Ryu Jin Sook;Oh Seung Joon;Im Ki Chun;Chen Gi Jeong;Lee So Ryung;Song Do Young;Im Soo Jeong;Moon Eun Sook;Kim Jong Hoon;Ahn Seung Do;Shin Seong Soo;Lee Kyeong Ryong
    • Radiation Oncology Journal
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    • v.22 no.4
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    • pp.288-297
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    • 2004
  • Puporse: The aims of this study were to evaluate the change of $[^18F]fluoromisonidazole$($[^18F]FMISO$) uptake in C3H mouse squamous cell carcinoma-VII (SCC-VII) treated with mild hyperthermia ($42^{circ}C$) and nicotinamide and to assess the biodistribution of the markers in normal tissues under similar conditions. Methods and Materials: $[^18F]FMISO$ was producedby our hospital. Female C3H mice with a C3H SCC-VII tumor grown on their extremities were used. Tumors were size matched. Non-anaesthetized, tumor-bearing mice underwent control or mild hyperthermia at $42^{circ}C$ for 60 min with nicotinamide (50 mg/kg i.p. injected) and were examined by gamma counter, autoradiography and animal PET scan 3 hours after tracer i.v. injected with breathing room air, The biodistribution of these agents were obtained at 3 h after $[^18F]FMISO$ injection. Blood, tumor, muscle, heart, lung, liver, kidney, brain, bone, spleen, and intestine were removed, counted for radioactivity and weighed. The tumor and liver were frozen and cut with a cryomicrotome into 10- um sections. The spatial distribution of radioactivity from the tissue sections was determined with digital autoradiography. Results: The mild hyperthermia with nicotinamide treatment had only slight effects on the biodistribution of either marker in normal tissues. We observed that the whole tumor radioactivity uptake ratios were higher in the control mice than in the mild hyperthermia with nicotinamide treated mice for $[^18F]FMISO$ ($1.56{\pm}1.03$ vs. $0.67{\pm}0.30$; p=0.063). In addition, autoradiography and animal PET scan demonstrated that the area and intensity of $[^18F]FMISO$ uptake was significantly decreased. Conclusion: Mild hyperthermla and nicotinamide significantly improved tumor hypoxia using $[^18F]FMISO$ and this uptake reflected tumor hypoxic status.

3D analysis of soft tissue around implant after flap folding suture (Flap folding suture를 활용한 판막의 고정에 따른 임플란트 주변 연조직 3차원 부피 변화 관찰)

  • Jung, Sae-Young;Kang, Dae-Young;Shin, Hyun-Seung;Park, Jung-Chul
    • Journal of Dental Rehabilitation and Applied Science
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    • v.37 no.3
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    • pp.130-137
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    • 2021
  • Purpose: The various suture techniques can be utilized in order to maximize the keratinized tissue healing around dental implants. The aim of this study is to compare the soft tissue healing pattern between two different suture techniques after implant placement. Materials and Methods: 15 patients with 18 implants were enrolled in this study. Simple implant placement without any additional bone graft was performed. Two different suture techniques were used to tug in the mobilized flap near the healing abutment after paramarginal flap design. Digital intraoral scan was performed at baseline, post-operation, stitch out, and 3 months after operation. The scan data were aligned using multiple points such as cusp, fossa of adjacent teeth, and/or healing abutment. After subtracting scan data at baseline with other time-point results, closed space indicating volume increment of peri-implant mucosa was selected. The volume of the close space was measured in mm3. The volume between two suture techniques at three time-points was compared using nonparametric rank-based analysis. Results: Healing was uneventful in both groups. Both suture technique groups showed increased soft tissue volume immediately after surgery. The amount of volume increment significantly decreased after 3 months (P < 0.001). Flap folding suture group showed higher median of volume increment than interrupted suture group after 3 months without any statistical significance (P > 0.05). Conclusion: After paramarginal flap reflection, the raised flaps stabilized by flap folding suture showed relatively higher volume maintenance after 3-month healing period. However, further studies are warranted.

Improvement of Signal Processing Circuit for Inspecting Cracks on the Express Train Wheel (고속 신호처리 회로에 의한 고속철도 차륜검사)

  • Hwang, Ji-Seong;Lee, Jin-Yi;Kwon, Suk-Jin
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2008.05a
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    • pp.579-584
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    • 2008
  • A novel nondestructive testing (NDT) system, which is able to detect a crack with high speed and high spatial resolution, is urgently required for inspecting small cracks on express train wheels. This paper proposes an improved signal processing circuits, which uses the multiple amplifying circuits and the crack indicating pulse output system of the previous scan-type magnetic camera. Hall sensors are arrayed linearly, and the wheel is rotated with static speed in the vertical direction to sensor array direction. Each Hall voltages are amplified, converted and immediately operated by using, amplifying circuits, analog-to-digital converters and $\mu$-processor, respectively. The operated results, ${\partial}V_H/{\partial}t$, are compared with a standard value, which indicates a crack existence. If the ${\partial}V_H/{\partial}t$ is larger than standard value, the pulse signal is output, and indicates the existence of crack. The effectiveness of the novel method was verified by examine using cracks on the wheel specimen model.

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A Development of Hanbok Jeogori Pattern from Virtual Garment Simulation - With a Focus on Women in their 50s - (가상착의를 활용한 한복 저고리 원형설계의 기초연구 - 50대 중년여성을 중심으로 -)

  • Lim, Ji-Young;Lee, Hae-Young
    • Fashion & Textile Research Journal
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    • v.14 no.4
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    • pp.607-613
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    • 2012
  • This study develops a Hanbok Jeogori pattern for middle-aged women with a 3D virtual-twin and virtual-garment simulation system. The including criteria for subjects in this study was a focus on women in their 50s, and a total of 345 females satisfying them were enrolled for 3D virtual model. Comparative Jeogori pattern, Baik & Choi's(2004) pattern, was selected for the development of Jeogori pattern. The results were: first, a new Jeogori pattern considerate of middle-aged women was developed. The basic numerical formula were: Front and back bust girth B/4+1.5, armhole depth B/4, sleeve width B/4, goedae width B/10-1.5 and git width 5.5. Second, according to the results of the new Jeogori patterns appearance evaluation, the new Jeogori pattern scored higher than the existing pattern in silhouette and ease amount, this confirmed that the new Jeogori pattern is appropriate for middle-aged women. Virtual models of production through data from 3D body scan, pattern draft, and virtual garment digital program were applied to a prototypic design method to enhance the fitness of ready-made Hanbok garments. This study serves as important basic data for ensuing studies that may utilize 3D Virtual Garment Simulation System with 2D patterns and for the future 3D Pattern Production Program development of Hanbok patterns.

A Development of the Uniform Pattern for Obese Junior-High School Girls from Virtual Garment Simulation (가상 착의 시스템에 의한 비만 여중생의 교복 원형 개발)

  • Lim, Ji-Young
    • The Research Journal of the Costume Culture
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    • v.19 no.2
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    • pp.245-254
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    • 2011
  • The purpose of this study was to develop uniform pattern of obese junior-high school girls by using the virtual twin and 3D virtual garment simulation system. The results were as follows; first, by using 3D virtual garment simulation, new uniform pattern considered obese junior-high school girls was development. The basic numerical formula were as follows; bust girth=B/2+2.5, armhole depth=B/4, front waist girth=W/4+1.8, back waist girth=W/4+1, front hip girth=H/4+1, back hip girth=H/4+1, chest width=chest width+1.5, back width=back width+1 and back neck width 8cm. Second, according to the results of the new uniform pattern's appearance evaluation, it estimated more highly than existing pattern in silhouette and ease amount, confirming that new uniform pattern is appropriate for the obese junior-high school girls. Also, new uniform pattern was evaluated to allow proper space length of bust, waist, abdomen and hip. Virtual models production through 3D body scan data, pattern draft and virtual garment digital program were applied to prototypic design method so as to enhance the fitness of ready-made garments. This study is expected to serve as one of important basic data for ensuing studies that may utilize 3D virtual garment simulation system with 2D patterns, and also for future 3D pattern production program development.

The Biometric Authentication Scheme Capable of Multilevel Security Control (보안레벨 조절이 가능한 바이오메트릭 인증 기법)

  • Yun, Sunghyun
    • Journal of the Korea Convergence Society
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    • v.8 no.2
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    • pp.9-14
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    • 2017
  • A fingerprint is unique to each person and can be represented as a digital form. As the fingerprint is the part of human body, fingerprint recognition is much more easy to use and secure rather than using password or resident card for user authentication. In addition, as the newly released smart phones have built-in camera and fingerprint sensors, the demand for biometric authentication is increasing rapidly. But, the drawback is that the fingerprint can be counterfeited easily and if it's exposed to the hacker, it cannot be reused. Thus, the original fingerprint template should be transformed for registration and authentication purposes. Existing transformation functions use passcode to transform the original template to the cancelable form. Additional module is needed to input the passcode, so it requires more cost and lowers the usability. In this paper, we propose biometric authentication scheme that is economic and easy to use. The proposed scheme is consisted of cancelable biometric template creation, registration and user authentication protocols, and can control several security levels by configuring the number of fingerprints and scan times. We also analyzed that our scheme is secure against the brute-force attack and the active attacks.

Clinical evaluation of Acupuncture on Herniated of Cervical Intervertebral Disc by DITI (컴퓨터 적외선(赤外線) 전신체열촬영(全身體熱撮影)으로 본 경추추간판(頸椎椎間板) 탈출증(脫出症)의 침구치료효과(鍼灸治療效果))

  • Lee, Geon-Mok
    • The Journal of Korean Medicine
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    • v.16 no.1 s.29
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    • pp.132-140
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    • 1995
  • Object : This study is designed to evaluate the correlation between the data of DITI(Digital Infrared Thermographic Imaging)examination and the changes of clinical symptom after the therapy of acupuncture in the patients with herniated cervical intervertebral disc. Content : The conservative therapy with acupuncture was performed during $4{\sim}5$ weeks, The acupuncture points of SI3, B62, TE3, G34, LI4, S36, GV26, G21, SII5 were used. In the pre- and post therapy, DITI examinations were performed in patients who had HIVD and were treated by acupuncture simultaneously, and then tried to correlate the results of clinical symptoms with the difference of thermographic findings at pre-acupuncture and post-acupuncture. Setting : The standard routine thermoghaphic examinations were performed with thermography(DITI) in the 15 patients with lumbar disc herniations at pre- and post acupuncture. Patient : Thermographic imaging of 15 cases were analyzed. They has disc herniations in X-ray, CT scan and MRI and they were treated by acupuncture theraphy in our hospital from March, 1994 to January, 1995. Result : 1) The causes were trauma(60%), retention of phlegm and fluid(8.7%) and cold & moisture(33.3%) 2) Levels of herniated cervical disc are C2/3(1 case). C3/4(2 cases), C5/6 & C6/7 (2 cases), C6/7(4 cases), Normal(6 cases). 3) Classifications of thermographic pattern are radiculopathy(80%), spot(13.3%), and nonspecific(6.7%) in order. 4) In evaluation Results of clinical symptom are Excellent(80%), Good(6.7%), and Poor(6.7%). Data of DITI are Excellent(80%), Good(6.7%), Fair(6.7%), and Poor(6.7%). Conclusion ; Acupuncture showed good results over 86.7% in clinical evaluation and 86.7% in DITI. Thermographic examination was valuable in the evaluation of therapeutic effect of acupuncture treatment.

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Breast Cytology Diagnosis using a Hybrid Case-based Reasoning and Genetic Algorithms Approach

  • Ahn, Hyun-Chul;Kim, Kyoung-Jae
    • Proceedings of the Korea Inteligent Information System Society Conference
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    • 2007.05a
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    • pp.389-398
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    • 2007
  • Case-based reasoning (CBR) is one of the most popular prediction techniques for medical diagnosis because it is easy to apply, has no possibility of overfitting, and provides a good explanation for the output. However, it has a critical limitation - its prediction performance is generally lower than other artificial intelligence techniques like artificial neural networks (ANNs). In order to obtain accurate results from CBR, effective retrieval and matching of useful prior cases for the problem is essential, but it is still a controversial issue to design a good matching and retrieval mechanism for CBR systems. In this study, we propose a novel approach to enhance the prediction performance of CBR. Our suggestion is the simultaneous optimization of feature weights, instance selection, and the number of neighbors that combine using genetic algorithms (GAs). Our model improves the prediction performance in three ways - (1) measuring similarity between cases more accurately by considering relative importance of each feature, (2) eliminating redundant or erroneous reference cases, and (3) combining several similar cases represent significant patterns. To validate the usefulness of our model, this study applied it to a real-world case for evaluating cytological features derived directly from a digital scan of breast fine needle aspirate (FNA) slides. Experimental results showed that the prediction accuracy of conventional CBR may be improved significantly by using our model. We also found that our proposed model outperformed all the other optimized models for CBR using GA.

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Video Index Generation and Search using Trie Structure (Trie 구조를 이용한 비디오 인덱스 생성 및 검색)

  • 현기호;김정엽;박상현
    • Journal of KIISE:Software and Applications
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    • v.30 no.7_8
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    • pp.610-617
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    • 2003
  • Similarity matching in video database is of growing importance in many new applications such as video clustering and digital video libraries. In order to provide efficient access to relevant data in large databases, there have been many research efforts in video indexing with diverse spatial and temporal features. however, most of the previous works relied on sequential matching methods or memory-based inverted file techniques, thus making them unsuitable for a large volume of video databases. In order to resolve this problem, this paper proposes an effective and scalable indexing technique using a trie, originally proposed for string matching, as an index structure. For building an index, we convert each frame into a symbol sequence using a window order heuristic and build a disk-resident trie from a set of symbol sequences. For query processing, we perform a depth-first search on the trie and execute a temporal segmentation. To verify the superiority of our approach, we perform several experiments with real and synthetic data sets. The results reveal that our approach consistently outperforms the sequential scan method, and the performance gain is maintained even with a large volume of video databases.

Development of Radiometric Scanning System for the Evaluation of the Pipeline (배관 검사용 Radiometric Scanning System 제작 및 시험)

  • Kim, Yong-Kyun;Hong, Seok-Boong;Chung, Chong-Eun;Lee, Yoon-Ho;Jung, Yong-Ha;Lee, Jeong-Ki
    • Journal of the Korean Society for Nondestructive Testing
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    • v.22 no.5
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    • pp.474-482
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    • 2002
  • One dimensional Radiometric scanning system was fabricated and tested as a filmless radiographic inspection system, which could be applied to the evaluation of the corrosion and deposits in the pipeline. This system is composed of the single radioactive source of the collimated focusing beam, and single scintillation detector of BGO, and the mechanical scanning system to transport and align the source and detector, and the operating software to automatically control the mechanical scan system. The performance of the system was simulated using GEANT4 software. This system is applied to one specimen having an artificial falw(flat bottom hole) in the pipe and the other specimen with thickness variation. For the inspection by using the radioactive source in the pipeline, it is possible to evaluate the corrosion and deposits in real time and without film.