• Radiation Oncology Journal
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• v.11 no.2
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• pp.193-203
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• 1993

In understanding radiosensitivity a new concept of inherent radiosensitivity based on individuality and heterogeneity within a population has recently been explored. There has been some discussion of possible mechanism underlying differences in radiosensitivity between cells. Ataxia telangiectasia (AT), a rare autosomal recessive genetic disorder, is characterized by hypersensitivity to ionizing radiation and other DNA damaging agents at the cellular level. There have been a lot of efforts to describe the cause of this hypersensitivity to radiation. At the cellular level, chromosome repair kinetics study would be an appropriate approach. The purpose of this study was to better understand radiosensitivity En an approach to investigate kinetics of induction and repair of $G_2$ chromatic bleaks using normal, AT heterozygous (ATH), and AT homozygous lymphoblastoid cell lines. In an attempt to estimate initial damage, $9-{\beta}-D-arabinosyl-2-fluoroadenine,$ an inhibitor of DNA synthesis and repair, was used in this study. It was found from this study that radiation induces higher chromatid breaks in AT than in normal and ATH cells. There was no significant differences of initial chromatid breaks between normal and ATH cells. Repair kinetics was the same for all. So the higher level of breaks in AT $G_2$ cells is thought to be a reflection of the increased initial damage. The amount of initial damage correlated well with survival fraction at 2 Gy of cell survival curve following radiation. Therefore, the difference of radiosensitivity in terms of $G_2$ chromosomal sensitivity is thought to result from the difference of initial damage.

• Korean Journal of Clinical Laboratory Science
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• v.36 no.2
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• pp.137-143
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• 2004

Erythrocyte sedimentation rate(ESR) measurements were performed in a total of 191 blood samples from patients below a hematocrit of 35% by both the Test-1(SIRE Analytical Systems, Udine, Italy) and the Westergren method, endorsed as the reference method for ESR by the International Council for Standardization in Hematology(ICSH). The corrected Westergren ESR values were also obtained applying the formula of Fabry (corrected ESR = ESR measured x 15/55-Hct). Linear regression analysis showed a close correlation (r=0.85) between the two methods both before and after ESR correction in total samples. There was no significant correlation difference between two methods in both two groups with hemoglobin $${\geq_-}9g/dl$$ and <9g/dl before and after ESR correction (r=0.873, r=0.827 respectively before correction and r=0.867, r=0.830 respectively after correction). Also, for two groups with hematocrit $${\geq_-}24%$$ and <24%, no significant difference was observed (r=0.859, r=0.792 respectively before correction and r=0.782, r=0.842 respectively after correction). However, for samples with <60mm of Westergren ESR before correction, a better correlation coefficient was obtained than samples with $${\geq_-}60mm$$(r=0.701, r=0.541 respectively). In corrected Westergren ESR, also samples that were obtained with <40mm showed better correlation than samples with $${\geq_-}40mm$$ (r=0.690, r=0.347 respectively). In conclusion, we found a good correlation between Test-1 and Westergren measurements in patients with anemia but an expert group discussion is required to solve discrepancy between two methods in blood samples with very high ESR.

• Archives of Craniofacial Surgery
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• v.18 no.3
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• pp.162-165
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• 2017

Background: It is controversial issue that heparin decreases thrombosis for microsurgical anastomosis, and its effective role is under discussion. This study is for proving whether low-dose heparin is preventing thrombosis in free flap reconstruction. Methods: Through chart reviews of 134 patients, using low-dose heparin for free tissue transfer from 2011 to 2016, retrospective analysis was performed. 33 patients received low-dose heparin therapy after surgery. And 101 patients received no-heparin therapy. Complications included flap necrosis, hematoma formation, dehiscence and infection. Results: In no-heparin therapy group, comparing the flap necrosis revealed 16 cases (15.84%). And, flap necrosis was 6 cases (18.18%) in low-dose heparin therapy group. The statistical analysis of flap necrosis rate showed no significant difference (p=0.75). The results showed that there was no significant difference of flap necrosis rate between two groups. Conclusion: In this study, patients in the low-dose heparin group had no significantly lower rates of flap failure compared with no-heparin group. This suggests that low-dose heparin may not prevent thrombosis and subsequent flap failure to a significant extent.

• Journal of Society of Preventive Korean Medicine
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• v.13 no.2
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• pp.19-26
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• 2009

Objectives : This study was investigated to the relationship ayurvedic constitution and each skin hydration and pH. Methods : The questionaire survey and skin analysis of female students attending university located in Chugnam was carried out in order to assess skin types according to ayurvedic constituion such as vata, pitta and kapha. Data analysis were used describe statistics, ANOVA in Duncan's multiple comparative test and Pearson's correlation by SPSS. Skin hydration and pH was measured by Corneometer and skin-pH meter. Results : The results of this study are as follows. First, in terms of knowledge of ayurvedic constitutional types most students are not aware of that. Second, the most common constitution in the ayurveda medical system was pitta. Third, in the analysis of skin type by constitution of ayurveda, vata had dry skin while pitta and kapha tended to have more combination skin. However, this result didn't show any statistically significant difference either. Forth, the analysis of skin tone by constitution of ayurveda showed that vata was white, and pitta and kapha were just average. Discussion and Conclusion : The results of this study was shown that the difference between Korean and Indian, so we should develop effective diagnosis tool for Korean people. In the future, we expect that ayurvedic skin and body program developed by this study spread and practical use at esthetic industry and domain of esthetics in Korea.

• Journal of Convergence for Information Technology
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• v.9 no.3
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• pp.128-133
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• 2019

The purpose of this study is to verify whether the data measured by the researcher and the smart shoe sensor data are the same or similar by performing the 6 - minute walking test and time up and go test after putting smart shoes on a normal person. Ten normal adult males participated. After wearing smart shoes, they performed a 6-minute walk test and a time up and go test. The results of this experiment show that the accuracy of the current sensor is high. The difference in the distance of the 6-minute walking test is that the difference is because the turning point, which is not calculated in the actual 30-m track, measures the distance. From this point of view, it can be seen that smart shoes measure more accurate distance and it is expected that various tests will be possible through smart sensors.

• Journal of Koreanology Reviews
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• v.1 no.1
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• pp.37-49
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• 2022

The purpose of this study is to discuss how Dongi People in ancient societies resided in the region including the Korean Peninsula shaped its economy, what kind of currency was used, and their economic activities using this currency. This study started from a skeptical point of view that the Dongi People were conducting economic activities with the currency used in the country made by the Jina People before and after the Gojoseon society. Currently, in China, all currencies issued in China are treated as their own currency. It is due to subjective interpretation from a nationalist point of view. Japan subjectively interprets and judges from a Japanese point of view and North Korea judges from the central point of view on the Korean Peninsula. This difference is due to the subjective interpretation from the researcher which has been affected by their associating academic area. This has caused the lack of objectivity. In other words, it means that there is a big difference in the perception of the interpretation of history between different academic areas. This study, therefore, tried to avoid the application of biased concept or academic research in order to define the distribution economics more objectively by conducting the study based on the literature sources from Chinese ancient books and field research materials as much as possible, as the study and research conducted based on the domestic sources are insufficient in the sense that there is a gap between different perceptions and interpretations. As a conclusion of this study, the excavation area of Myeong-do-jeon is perfectly consistent with the old river area of Gojoseon, and in particular, considering Gojoseon was in the hostile relationship with Yan, it was found that only Myeong-do-jeon was used without using any other Chinese currency in the entire Gojoseon area, not just some areas. It is also a decisive clue to prove that it is not the Yan currency. The limitation of this study in developing the discussion different from the current research and study is that there was a lack of exploration and investigation of various documents and relics. For future research, this study will become more meaningful when it is conducted simultaneously with the discovering of new documents as well as the relics.

• The Journal of Internal Korean Medicine
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• v.44 no.6
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• pp.1271-1278
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• 2023

Objective: The 19 Mechanisms of Disease were first described in Huangdi Neijing. When examining Yixuexinwu, three descriptions that were different from Huangdi Neijing were found. Methods and Results: After examining the two books, three differences in the description of the 19 Mechanisms of Disease were discovered: 1) The upper and lower locations of dyspnea (喘症) are reversed. 2) The ratio of provisions for "fire (火)" and "cold (寒)" is different. 3) The organ affiliation for pain is different. Conclusion: 1) The upper and lower locations of dyspnea (喘症) are reversed. : Regarding external contraction dyspnea (外感喘), Yixuexinwu used the disease of the upper location (lung 上, 肺) in the same way as in Huangdi Neijing. In terms of internal damage (內傷喘), it was separately classified as a disease of the lower location (kidney 下, 腎). 2) The ratio of provisions for "fire (火)" and "cold (寒)" is different. : Arithmetically, if you round off the number after calculating the fraction, the difference between the two ratios becomes the same. Theoretically, five provisions of "fire" are replaced by four provisions of "heat (熱)", and the difference in ratios is exactly the same. Empirically, it emphasizes that there are more illnesses from fire and heat than from cold. 3) The organ affiliation for pain is different. : Huangdi Neijing described general inflammatory pain, while the Yixuexinwu described only stress-related abdominal pain (肝木乘脾 腹痛).

• Journal of Radiation Protection and Research
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• v.49 no.1
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• pp.50-64
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• 2024

Background: The reference dose coefficients (DCs) of the International Commission on Radiological Protection (ICRP) have been widely used to estimate organ doses of individuals for risk assessments. This approach has been well accepted because individual anatomy data are usually unavailable, although dosimetric uncertainty exists due to the anatomical difference between the reference phantoms and the individuals. We attempted to quantify the individual variation of organ doses for photon external exposures by calculating and comparing organ DCs for 30 individuals against the ICRP reference DCs. Materials and Methods: We acquired computed tomography images from 30 patients in which eight organs (brain, breasts, liver, lungs, skeleton, skin, stomach, and urinary bladder) were segmented using the ImageJ software to create voxel phantoms. The phantoms were implemented into the Monte Carlo N-Particle 6 (MCNP6) code and then irradiated by broad parallel photon beams (10 keV to 10 MeV) at four directions (antero-posterior, postero-anterior, left-lateral, right-lateral) to calculate organ DCs. Results and Discussion: There was significant variation in organ doses due to the difference in anatomy among the individuals, especially in the kilovoltage region (e.g., <100 keV). For example, the red bone marrow doses at 0.01 MeV varied from 3 to 7 orders of the magnitude depending on the irradiation geometry. In contrast, in the megavoltage region (1-10 MeV), the individual variation of the organ doses was found to be negligibly small (differences <10%). It was also interesting to observe that the organ doses of the ICRP reference phantoms showed good agreement with the mean values of the organ doses among the patients in many cases. Conclusion: The results of this study would be informative to improve insights in individual-specific dosimetry. It should be extended to further studies in terms of many different aspects (e.g., other particles such as neutrons, other exposures such as internal exposures, and a larger number of individuals/patients) in the future.

• Journal of Korean Society of Rural Planning
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• v.18 no.2
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• pp.27-37
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• 2012

The purpose of this study is on comparing complementary forest of village between Korea and China. For this, Jinan of Korea and Qingzhou of China were selected through the pre-survey about the representative region of both country. The main research method was literature study, field study and interview with local residents. The comparative analysis between two regions was performed by frequency analysis of surveyed data. Which shows complementary forest of village in two regions has so much in common and also has many differences which is related with the local practical life. As a result, it was identified that the area and remained number, concentration degree of Jinan were greater than those of Cheongju. But it was identified that the linear form and location were similar in both regions. Through these identification, it is helpful to establish policy direction of both countries about the complementary forest.

• 제어로봇시스템학회:학술대회논문집
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• 1996.10a
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• pp.434-437
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• 1996

Symmetry is one of the important structural properties of shapes both in perceptual psychology and in computer vision. Recently, a number of automatic symmetry finding algorithms have been reported. Among them, the algorithm based on the use of principal axes of objects is the most general and practical. It is, however, of no use when shapes concerned have some asymmetry. Asymmetric shapes which make us associate with certain kinds of symmetry are practically important and they are called shapes with potential symmetry in this paper. The algorithm we have already proposed can cope with those shapes having potential axial symmetry. The algorithm employs a reflected image of the original and a certain evaluation function. In the former paper, areal minimization was employed for the evaluation function and it yielded satisfactory experimental results. However, it could not cope with those shapes which have larger asymmetry. In this paper, we propose the employment of variance as an alternative evaluation index with respect to the difference image between the reflected and the original shape. The technique is examined its performance by real video images as well as synthetic data. Experimental results are shown and discussion is given.