• Transactions of Materials Processing
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• v.15 no.5 s.86
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• pp.395-401
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• 2006

It is reported that semi-solid forming process takes many advantages over the conventional forming process, such as a long die life, good mechanical properties and energy saves. It is important to predict the deformation behavior for optimization of the forging process with semi-solid materials and to control liquid segregation for mechanical properties of materials. But rheology material has thixotropic, pseudo-plastic and shear-thinning characteristics. So, it is difficult for a numerical simulation of the rheology process to be performed because complicated processes such as the filling to include the state of the free surface and solidification in the phase transformation must be considered. General plastic or fluid dynamic analysis is not suitable for the analysis of the rheology material behavior. Recently, molecular dynamics is used for the behavior analysis of the rheology material and turned out to be suitable among several methods. In this study, molecular dynamics simulation was performed for the control of liquid segregation, forming velocity, and viscosity in compression experiment as a part of study on the analysis of rheology forming process.

• Journal of Korean Public Health Nursing
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• v.21 no.2
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• pp.217-229
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• 2007

Purpose: This study sought to investigate the relationship between smoking, drinking and the mental health of adolescents. Method: The study subjects included 1,092 randomly sampled third-year middle and high school students from N-City and the L-Kun area in Chonbuk Province. The data were collected using an anonymous questionnaire developed by the Ministry of Health and Welfare(2005). The data were analyzed using the SPSSWIN 15.0 Program. Result: The smoking rate in the adolescents was 10.1%, and the drinking rate was 43.2%. The stress recognition rate in normal daily life was 45.5%, the frequency of depressive symptoms was 33.2% and 40.0% of the subjects reported that they wanted to die at some point within the past year. The rate of stress recognition, depressive symptom experience, suicidal planning and attempt in smokers and drinkers was higher than that in non-smokers and non-drinkers (p<.05). Especially, the frequency of suicidal thoughts was higher in the drinkers than in the non-drinkers (p<.05). Conclusion: The smoking and drinking status of the adolescents was correlated with their mental health a sit relates to stress, depression and suicide. Therefore, an effective program for the prohibition of cigarette smoking and alcohol consumption is needed in order to prevent smoking and alcohol consumption in adolescents and improve their mental health status.

• Journal of environmental and Sanitary engineering
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• v.14 no.4
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• pp.77-84
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• 1999

Most river quality problems are generated by pollutants which are discharged into the river as a consequence of human activities. And eutrophication occurs when water is over enriched with nutrients, principally nitrate and phosphate. Both these nutrients are found in many waste products, especially sewage even when the waste is treated. Eutrophication is concerned in lakes, but it also causes problems in river. Wide growth of Phytoplankton in rivers, leads to blockage of channels, but the main concern is deoxygenation because of the increase in plant life's demand for oxygen in revers. Fish, plant and animals die due to lack of oxygen. The increase of algae floating on the tops of water looks ugly and has attracted public attention and concern in recent years. One way of controlling eutrophication is to restrict the amount of waste carrying nitrate or phosphate from entering the water in the first place. another way is to remove it from the water after it has been entered. This study was carried out to investigate on the trophic state, nutrients and Chlorophyll-a concentration in the Han River. The results were as follows:1. Concentrations of total nitrogen were 2.208~9.221(5.133)mg/$\ell$2. Concentrations of total phosphate were 0.045~0.614(0.195)mg/$\ell$3. Chlorophyll-a concentration were $0.0-25.3(9.6)mg/m^3$.4. The correlation coefficient between T-P and Chlorophyll-a concentration was r=-0.856 at Sungsan sampling site.5. The correlation coefficient was r=-0.578~-0.767, between Paldang Dam outflow and Chlorophyll-a concentration at all sampling sites.

• Journal of Computational Design and Engineering
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• v.3 no.1
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• pp.63-70
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• 2016

Deep drawing is a forming process in which a blank of sheet metal is radially drawn into a forming die by the mechanical action of a punch and converted to required shape. Deep drawing involves complex material flow conditions and force distributions. Radial drawing stresses and tangential compressive stresses are induced in flange region due to the material retention property. These compressive stresses result in wrinkling phenomenon in flange region. Normally blank holder is applied for restricting wrinkles. Tensile stresses in radial direction initiate thinning in the wall region of cup. The thinning results into cracking or fracture. The finite element method is widely applied worldwide to simulate the deep drawing process. For real-life simulations of deep drawing process an accurate numerical model, as well as an accurate description of material behavior and contact conditions, is necessary. The finite element method is a powerful tool to predict material thinning deformations before prototypes are made. The proposed innovative methodology combines two techniques for prediction and optimization of thinning in automotive sealing cover. Taguchi design of experiments and analysis of variance has been applied to analyze the influencing process parameters on Thinning. Mathematical relations have been developed to correlate input process parameters and Thinning. Optimization problem has been formulated for thinning and Genetic Algorithm has been applied for optimization. Experimental validation of results proves the applicability of newly proposed approach. The optimized component when manufactured is observed to be safe, no thinning or fracture is observed.

• Clinical and Experimental Reproductive Medicine
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• v.46 no.4
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• pp.206-210
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• 2019

Mucopolysaccharidosis type II (MPS II) is a rare X-linked recessive lysosomal storage disease caused by mutation of the iduronate-2-sulfatase gene. The mutation results in iduronate-2-sulfatase deficiency, which causes the progressive accumulation of heparan sulfate and dermatan sulfate in cellular lysosomes. The phenotype, age of onset, and symptoms of MPS II vary; accordingly, the disease can be classified into either the early-onset type or the late-onset type, depending on the age of onset and the severity of the symptoms. In patients with severe MPS II, symptoms typically first appear between 2 and 5 years of age. Patients with severe MPS II usually die in the second decade of life although some patients with less severe disease have survived into their fifth or sixth decade. Here, we report the establishment of a preimplantation genetic diagnosis (PGD) strategy using multiplex nested polymerase chain reaction, direct sequencing, and linkage analysis. Unaffected embryos were selected via the diagnosis of a single blastomere, and a healthy boy was delivered by a female carrier of MPS II. This is the first successful application of PGD in a patient with MPS II in Korea.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.24 no.5
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• pp.508-513
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• 2015

In this study, the effect of the helix angle and rake angle of a flat end-mill in the milling of titanium alloy was investigated. Tool shape parameters such as helix angle and rake angle affect the cutting force, cutting zone temperature, vibration, and chip flow mechanism, which in turn determine tool life, surface integrity, and dimensional accuracy of the milling process. To investigate the effect of the helix and rake angles, a certain range of parameters was selected, and three-dimensional tool models were generated for finite element analysis (FEA) for each case. The cutting force and pressure on the tool flank face and rake face were investigated by FEA. Further, several tool models were proposed for machining tests. The cutting force characteristics were investigated by the machining tests.

• Transactions of Materials Processing
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• v.13 no.1
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• pp.84-89
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• 2004

There is a growing interest to replace the commercial steels with non-heat treated steels, which does not involve the spheroidization and quenching-tempering treatment. However, Non-heat treated steels should satisfy high strength and good formability without performing heat treatment. Therefore, it is important to investigate optimum materials showing a good combination of strength and formability after the drawing process. In this study, Dual-Phase Steels were studied as candidate materials for non-heat treated steels, which have different martensite morphologies and volume fractions obtained through heat-treatment of intercritical quenching (IcQ), intermediate quenching (ImQ) and step quenching (SQ). The mechanical properties of DP steels were measured by tension and compression tests. Also, the cold formability of three DP steels which have similar tensile strength value was investigated by estimating the deformation resistance and the forming limit. The deformation resistance which is important factor in determining die life was estimated by calculating the deformation energy. And the forming limit was estimated by measuring the critical strain revealing crack initiation at the notch tip of the specimens.

• Journal of Korean Academy of Nursing
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• v.30 no.3
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• pp.584-594
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• 2000

The purpose of this study was to identify emotional responses, of stroke patients using Q analysis. From the data analysis, five types of emotional responses in stroke patients were classified as follows. 1. Acceptance and Overcoming : They attached to life strongly and had self-confidence of recovery. They were striving against their situation through using anything else good for their recovery. 2. Anger Type : They recognized a labile feeling and were angered easily. They had a self-confident and self-esteemed personality before they had a stroke. 3. Conflict Type : They wanted interaction with others. This individual recognized that no one knows their agonies. They were thankful to god or their family, while they could not control their minds. Their family supports were low. 4. Deficiency of self-esteem Type : They had a self-confidence of recovery, but they were in fear of interaction with others. Especially, they were ashamed of themselves. They have a high sense of responsibility and nigh self-esteem for themselves before they had a stroke. 5. Despair Type. : They were sorry to trouble their family. They felt depression, anxiety, darkness, uselessness of themselves, and they wanted to die. They recognized financial burden. for their family. The characteristics of the five types of stroke patient identified in this study will be used to assess emotional nursing needs for stroke patients. The findings of this study will provide practical guidelines for developing nursing interventions for stroke patients based on the characteristics of subjectivity types.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2006.05a
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• pp.19-20
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• 2006

As the Mobile and Display technology are being developed quickly, new wireless devices are released in great numbers. They reduce existing devices' life time and demand a reduction of developing period of portable devices. With these demands, existing film cutting mold used many films of portable devices, especially LCD Display, needs to be more precise, and cheaper. In this research, we have analyzed machining characteristics of cutter shapes, materials, and cutting conditions for application to other films. Cutter edge was machined by slot cutting method and CAD program to select the cutter shape and cutter angle. Also, we have determined the optimal cutting conditions using high speed machining experiments to improve the productivity.

• Molecules and Cells
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• v.42 no.12
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• pp.836-839
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• 2019

A tumor is an abnormal mass of tissue that arises when cells divide more than they should or do not die when they should. The cellular decision regarding whether to undergo division or death is made at the restriction (R)-point. Consistent with this, an increasingly large body of evidence indicates that deregulation of the R-point decision-making machinery accompanies the formation of most tumors. Although the R-point decision is literally a matter of life and death for the cell, and thus critical for the health of the organism, it remains unclear how a cell chooses its own fate. Recent work demonstrated that the R-point constitutes a novel oncogene surveillance mechanism operated by R-point-associated complexes of which RUNX3 and BRD2 are the core factors (Rpa-RX3 complexes). Here, we show that not only RUNX3 and BRD2, but also other members of the RUNX and BRD families (RUNX1, RUNX2, BRD3, and BRD4), are involved in R-point regulation.