• Title/Summary/Keyword: Diagnostic validation

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Diagnostic for Smoothing Parameter Estimate in Nonparametric Regression Model

  • In-Suk Lee;Won-Tae Jung
    • Communications for Statistical Applications and Methods
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    • v.2 no.2
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    • pp.266-276
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    • 1995
  • We have considered the study of local influence for smoothing parameter estimates in nonparametric regression model. Practically, generalized cross validation(GCV) does not work well in the presence of data perturbation. Thus we have proposed local influence measures for GCV estimates and examined effects of diagnostic by above measures.

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A Systematic Review of Validation Studies on Depression Rating Scales in Korea, with a Focus on Diagnostic Validity Information : Preliminary Study for Development of Korean Screening Tool for Depression (국내 우울증 평가도구 타당화 연구의 체계적 고찰-진단적 타당성을 중점으로 : 한국형 우울 선별 도구 개발을 위한 예비 연구)

  • Jung, Sooyun;Kim, Shin-Hyang;Park, Kiho;Jaekal, Eunju;Lee, Won-Hye;Choi, Younyoung;Lee, Seung-Hwan;Choi, Kee-Hong
    • Anxiety and mood
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    • v.13 no.2
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    • pp.53-59
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    • 2017
  • Reliable and valid diagnostic screening tools in the primary care setting enable accurate estimation of depression in individuals at risk or in need of treatment, and provide patients with an opportunity to receive optimal treatments. Although there have been extensive studies on screening tools for depression used in domestic mental health settings, there is little consideration and lack of a thorough review of the diagnostic validity of screening tools. In the current review, we selected 13 representative screening tools for depression which were evaluated in a total of 19 validation studies conducted in Korea. We summarized DSM-5 target domains, diagnostic indices, sensitivity, specificity, cut-off scores, and diagnostic validity information for each tool. Finally, the depression measurement expert group was constituted to evaluate the current status of screening tools for depression, and their recommendations for a new screening tool were summarized. This study was conducted as part of the Mental Health Technology Development project to develop the Korean screening tool for depression (K-DEP).

A Brief Screening Tool for PTSD: Validation of the Korean Version of the Primary Care PTSD Screen for DSM-5 (K-PC-PTSD-5)

  • Jung, Young-Eun;Kim, Daeho;Kim, Won-Hyoung;Roh, Daeyoung;Chae, Jeong-Ho;Park, Joo Eon
    • Journal of Korean Medical Science
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    • v.33 no.52
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    • pp.338.1-338.5
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    • 2018
  • The purpose of this study was to develop and evaluate psychometrically the Korean version of the Primary Care Posttraumatic Stress Disorder Screen for the Diagnostic and Statistical Manual-fifth edition (K-PC-PTSD-5). In total, 252 participants were interviewed with the Structured Clinical Interview for Diagnostic and Statistical Manual-fifth edition-research version (SCID-5-RV). The K-PC-PTSD-5 showed good internal consistency (${\alpha}=0.872$), test-retest reliability (r = 0.89), and concurrent validity (r = 0.81). A score of 3 was identified as the threshold for clinically significant posttraumatic stress disorder (PTSD) symptoms. Overall, the results indicate that the K-PC-PTSD-5 is a useful, timesaving instrument for screening PTSD symptoms.

Validation of Synovial Fluid Clinical Samples for Molecular Detection of Pathogens Causing Prosthetic Joint Infection Using GAPDH Housekeeping Gene as Internal Control

  • Jiyoung Lee;Eunyoung Baek;Hyesun Ahn;Youngnam Park;Geehyuk Kim;Sua Lim;Suchan Lee;Sunghyun Kim
    • Biomedical Science Letters
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    • v.29 no.4
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    • pp.220-230
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    • 2023
  • Identification of the pathogens causing infection is important in terms of patient's health management and infection control. Synovial fluids could be used as clinical samples to detect causative pathogens of prosthetic joint infections (PJIs) using molecular diagnostic assays, therefore, normalization and validation of clinical samples are necessary. Microbial culture is considered the gold standard for all infections, including PJIs. Recently, molecular diagnostic methods have been developed to overcome the limitation of microbial culture. Therefore, guideline for validating clinical samples to provide reliable results of molecular diagnostic assays for infectious diseases is required in clinical field. The present study aimed to develop an accurate validating method of synovial fluid clinical samples using GAPDH gene as an internal control to perform the quantitative PCR TaqMan probe assay to detect pathogens causing PJIs.

A study on the development of ADEX (ADEX 개발에 관한 연구)

  • Oh, Jae-Eung;Shin, Joon;Hahn, Chang-Soo
    • 제어로봇시스템학회:학술대회논문집
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    • 1992.10a
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    • pp.453-456
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    • 1992
  • Diagnostic prototype expert system was developed by analyzing the measured acoustical data of automobile. For the utilities of this system, 1/3 octave filter(band-pass filter) and A/D converter were used for data acquisition and then information was analyzed using signal processing technique and pattern recognition by Hamming network algorithm. In order to raise the reliability of the diagnostic results, fuzzy inference technique was applied and, the results were displayed as graphical method to help the novice in diagnostic field. The validation of this diagnostic system was checked through experiments and it showed and acceptable performance for diagnostic process.

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Validity of nursing diagnosis : Fluid volume deficit (체액량 부족(Fluid volume deficit) ; 간호진단의 타당도 조사 연구)

  • Byun Young-Soon;Kim Sook-Young
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.1 no.2
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    • pp.207-218
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    • 1994
  • A validation of the nursing diagnosis 'fluid volume deficit' was completed by using the diagnostic content validity method. Articles pertaining to fluid volume depletion were reviewed to identify the signs and symptoms used to describe the nursing diagnosis. The topics addressed in the articles included hypovolemic shock, hemorrhage, trauma, fluid balance, hydration, burn injury, thirst, dehydration. A validation instruments was constructed of 52 signs and symptoms. A validation tool was examined by expert nurses group who work on intensive care unit, kidney transplantation unit, internal medicine and general surgery unit. The study sample rated the signs and symptoms on a scale from one to five, evaluating their relevance to this diagnosis. Of the 52 signs and symptoms on the validation tool, 10 were categorized as critical indicators and 34 were categorized as defining characteristics.

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A Study on the Validation system of Detection for Biological Agents Using Real-Time PCR (실시간 중합효소 연쇄반응을 활용한 생물작용제 검증시스템 연구)

  • Cha, Younggil;Koo, Bonwoo;Kim, Seongjoo;Kim, Namil;Park, Hanoh
    • Journal of the Korea Institute of Military Science and Technology
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    • v.20 no.5
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    • pp.726-732
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    • 2017
  • Bacillus anthracis, Vibrio cholerae, Variola virus and Shigella dysenteriae are classified as category A and B biological weapons. In this study suggest that 4 genes of Bacillus anthracis, 2 genes of Vibrio cholerae, 1 gene of Variola virus and 1 gene of Shigella dysenteriae were detective 50~500 fg of target DNA per reaction using real-time PCR based assay. Also analytical specificity did not show any cross-reactivity with other related bacteria. Reliable and one reaction could be effective early diagnostic and treatment for detection of unknown samples.

Diagnostic Medical Image Compression Method using Visually Lossless Threshold on JPEG2000 (JPEG2000에서 시각적 무손실 임계값을 이용한 진단의료영상 압축기법)

  • Bong, Jeong-Sik;Yang, Gi-Joo;Jeon, Joon-Hyeon
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.34 no.7C
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    • pp.671-680
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    • 2009
  • The diagnostic medical images(CT, MRI) in PACS require large storage and long transmission time. A simple and cheap way of overcoming these limitations is to increase the compression ratio. However, this requires a clinical validation for accurate diagnostic applications. The aim of this paper is to improve the compression efficiency of lossless JPEG2000 for diagnostic CT images by performing a visual-Iossless threshold filtering in high frequency subband. A proposed method, based on 5/3 reversible DWT, provides different subband-threshold values according to the compression ratio and gives the high subjective quality to reconstructed diagnostic CT images.

Automobile diagnosis by euro-Fuzzy Technique (뉴로-퍼지 기법에 의한 자동차 진단)

  • Shin, Joon;Oh, Jae-Eung
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.16 no.10
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    • pp.1833-1840
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    • 1992
  • In the diagnostic process for automobile, Neuro-Fuzzy technique was compared with the conventional diagnostic method for the verification of performance, and proto-type system was developed. For the utilities of the system, 1/3 octave filter(band-pass filter) and A/D converter were used for data acquisition and then data were analyzed using octave band processing and pattern recognition using hamming network algorithm. In order to raise the reliability of the diagnostic results by considering many operating variables and condition of automobile to be diagnosed, fuzzy inference technique was applied in combining several information. The validation of this diagnostic system was examined through computer simulation and experiment, and it showed an acceptable performance for diagnostic process.