• 제목/요약/키워드: Diagnostic pathology

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Focal nodular hyperplasia: Tripie-contrast enhanced MR imaging using gadolinium chelates, mangafodipir trisodium, and ferumoxides

  • Kim, Joo-Hee;Kim, Myeong-Jin;Park, Young-Nyun;Kim, Kyung-Sik;Lee, Jong-Tae;Yoon, Hyung-Sik
    • 대한자기공명의과학회:학술대회논문집
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    • 대한자기공명의과학회 2001년도 제6차 학술대회 초록집
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    • pp.140-140
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    • 2001
  • We present two cases of surgically proven focal nodular hyperplasia whou underwent tri contrast-enhance MR imaging using gadolinium chelates, mangafodipir trisodium, and ferumoxides After the unehanced MR images were obtained, dynamic gadolinium-enhanced T1-weighted imagi were performed, then mangafodipir enhanced and ferumoxides-enhanced images were obtained. In one case, the mass was isointense on both T1- and T2-weighted images on the unehanced M images, iso and slightly hyperintense on ferumoxides-enhanced FSE and GRE images, strong hyperintense on the mangafodipir enhanced and gadolinium enhanced arterial phase images. In th other case, the mass was isointense on T2-weighted and hypointense on T1-weighted image isointense on ferumoxides-enhanced images, and hyperintense on mangafodipir enhanced an gadolinium enhanced arterial phase images. Triple contrast enhanced MR images were useful correctly diagnose these two cases preoperatively.

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Pathological findings of the mixed infection with canine distemper virus and Streptococcus canis on farmed badger

  • Kim, Ji-hyeon;Lee, Kyunghyun;Jung, Ji-Youl;Choi, Eun-Jin;Kim, Ha-Young;So, ByungJae
    • 한국동물위생학회지
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    • 제41권1호
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    • pp.51-55
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    • 2018
  • Herein, we report a case of badgers showing high morbidity and mortality rate due to the mixed infection of canine distemper virus (CDV) and Streptococcus canis (S. canis) in a farm where wild animal, badger, is being reared for herbal medicine. During the period of about one month, 120 out of 320 badgers showed severe respiratory symptoms and died, and 3 bodies were submitted to the Animal and Plant Quarantine Agency for disease diagnosis. The lung with the most severe necropsy findings failed to collapse and showed dark reddening and had yellowish nodules on the cut surface. The characteristic and common histopathologic findings include multifocal necrosis with hemorrhage of the lung, severe lymphoid depletion of the spleen and intracytoplasmic or intranuclear inclusion bodies in almost all organs. Finally, CDV and S. canis were identified by immunohistochemistry and bacterial isolation, respectively. This is the first mixed infection case of CDV and S. canis in badgers being raised on the farm.

병리업무의 전산화(I) - 자동코딩 방식을 이용한 진단병리 업무의 체계화 및 기타 병리제반 업무의 간소화에 대한 연구 (Computerization of Surgical Pathology Work - A Study for Systemization of Surgical Pathology Work using Automatic Coding System and Simplification of Other Works in Pathology Department)

  • 김동석;최원희;이태숙
    • Journal of Yeungnam Medical Science
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    • 제7권1호
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    • pp.215-219
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    • 1990
  • 자동코딩 방식을 이용함으로써 업무 수행능력이 배가되고 용이하게 호출이 가능하며 디스켓에 따로 저장하는 보완장치가 있으므로 상당히 안전하리라 생각된다. 대형컴퓨터에 비해 그 소요경비가 무척 절감되었으며 언제든지 프로그램 보완이 가능하여 앞으로의 이용이 주목된다 하겠다.

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Key Imaging Findings for the Prospective Diagnosis of Rare Diseases of the Gallbladder and Cystic Duct

  • Shintaro Ichikawa;Naoki Oishi;Tetsuo Kondo;Hiroshi Onishi
    • Korean Journal of Radiology
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    • 제22권9호
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    • pp.1462-1474
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    • 2021
  • There are various diseases of the gallbladder and cystic duct, and imaging diagnosis is challenging for the rare among them. However, some rare diseases show characteristic imaging findings or patient history; therefore, familiarity with the imaging presentation of rare diseases may improve diagnostic accuracy and patient management. The purpose of this article is to describe the imaging findings of rare diseases of the gallbladder and cystic duct and identify their pathological correlations with these diseases.

Rapid Detection and Identification of Wuchereria bancrofti, Brugia malayi, B. pahangi, and Dirofilaria immitis in Mosquito Vectors and Blood Samples by High Resolution Melting Real-Time PCR

  • Thanchomnang, Tongjit;Intapan, Pewpan M.;Tantrawatpan, Chairat;Lulitanond, Viraphong;Chungpivat, Sudchit;Taweethavonsawat, Piyanan;Kaewkong, Worasak;Sanpool, Oranuch;Janwan, Penchom;Choochote, Wej;Maleewong, Wanchai
    • Parasites, Hosts and Diseases
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    • 제51권6호
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    • pp.645-650
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    • 2013
  • A simple, rapid, and high-throughput method for detection and identification of Wuchereria bancrofti, Brugia malayi, Brugia pahangi, and Dirofilaria immitis in mosquito vectors and blood samples was developed using a real-time PCR combined with high-resolution melting (HRM) analysis. Amplicons of the 4 filarial species were generated from 5S rRNA and spliced leader sequences by the real-time PCR and their melting temperatures were determined by the HRM method. Melting of amplicons from W. bancrofti, B. malayi, D. immitis, and B. pahangi peaked at $81.5{\pm}0.2^{\circ}C$, $79.0{\pm}0.3^{\circ}C$, $76.8{\pm}0.1^{\circ}C$, and $79.9{\pm}0.1^{\circ}C$, respectively. This assay is relatively cheap since it does not require synthesis of hybridization probes. Its sensitivity and specificity were 100%. It is a rapid and technically simple approach, and an important tool for population surveys as well as molecular xenomonitoring of parasites in vectors.

질병예측자료로서 사과(四科) . 사류형상(四類形象)의 의의와 미병진단적 가치 연구 (Study on the Meaning of Four Subjects and Four Species as a Disease-Prediction Data and Diagnostic Value on Ante-Disease)

  • 김종원;전수형;이인선;김규곤;이용태;김경철;엄현섭;지규용
    • 동의생리병리학회지
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    • 제23권2호
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    • pp.325-330
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    • 2009
  • In Korea, medical diagnostic equipments and biochemical examination can not be used in order for diagnosing sub-healthy state or ante-disease state in oriental medicine clinic. So morphic analogical method used in oriental medicine can be a good tool as a disease-predictable signs in order to enable preventive diagnosis and therapy. Therefore the four geometrical subjects; Essence, Pneuma, Spirit, Blood(四科;精氣紳血) and the four taxonomical species; Pisces, Quadruped, Aves, Carapaces(四類;魚走鳥甲) are chosen as morphic models in this paper. The differences of two classifying methods with four subjects and four species were as follows. The diagnostic category was meta-medical and synthetic against medical specific. The diagnostic object was body in contrast with face. They were able to be applicant in psychology and classification of characteristics against diagnostics and therapeutics directly in oriental medicine. The theoretical basis was basic diagrams of four unit-fluids of body and morphological analogy with four animal species respectively. And the therapeutic aims were systemic pathogenesis following five phase theory against congestion and deficiency of Essence, Pneuma, Spirit, Blood. The four subjects and four species are mixed each other practically in clinic. But it should be used limitedly because of the above reasons described and must divide the principal and secondary factors and follow the pathology of principal shape factor. In order to improve the diagnostic value of ante-disease state, the discriminable standards, measurement methods, limit of interrelating interpretation and the criteria of abnormal disproportion were needed to be defined more clearly in advance.

국내 아메리칸 핏불테리어에서 발생한 열사병 증례 보고 (Heatstroke occurred in an American Pit Bull Terrier in Korea)

  • 이승희;정지열;정재훈;이현경;박중원;이경기;김종완;소병재;윤순식
    • 한국동물위생학회지
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    • 제41권3호
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    • pp.211-216
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    • 2018
  • Heat stroke in a dog is a life-threatening syndrome characterized by a high body temperature over $41^{\circ}C$, by the central nervous system dysfunction, and by multiple organ dysfunction. A 11-month-old male American Pit Bull Terrier was presented to clarify the cause of death to diagnostic laboratory. This dog showed clinical signs such as high body temperature ($42^{\circ}C$), severe tachypnea, hematochezia, epistaxis and hemoptysis after transportation at hot summer time. At necropsy, there were hemorrhages in skin, serosa of stomach and small intestine, and also dark red fluid in lumen of intestine. Histopathologic examination revealed extensive hemorrhages in stomach, muscle, skin, and tongue. In microbiology, pathologic bacteria such as Pasteurella, Boedetella, Salmonella, Clostridium, and circulating virus in Korea such as CDV, CIV, CAV, CHV, CCV, CPIV were negative except CPV. There were many gross and microscopic lesions suggesting hest stroke while pathologic agents and related lesions were not detected. Therefore we diagnosed this case as heatstroke.

Future Directions in Veterinary Pathology

  • Cho, Doo-Youn
    • 한국수의병리학회:학술대회논문집
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    • 한국수의병리학회 2000년도 추계학술대회 및 정기총회
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    • pp.11-11
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    • 2000
  • The development of new investigative technology and the changing roles of other biological and medical disciplines will result in major changes in the way veterinary pathology is practiced in the future. Unless the pathologists strategically prepare themselves to adopt and incorporate these changes into their modest operandi, the veterinary pathologist's traditional dominance in the diagnosis of spontaneous animal diseases and experimentally induced lesions in animals will be at risk. Although the distinguishing feature of pathologist is their artful ability to read and interpret the pathologic changes of cells and tissues, we must strive to enhance and expand our ability beyond and above the simple reading of H&E stained slides. Also, we must be prepared to meet the ever increasing demand of diagnostic accuracy and timeliness. To do so, we have to employ the new biological and toxicological technologies into our routine. (omitted)

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Canine Multicentric Large B Cell Lymphoma with Increased Mott Cells Diagnosed by Flow Cytometry

  • Yang, Yeseul;Jung, Jae-Ha;Hwang, Sung-Hyun;Kim, Yongbaek
    • 한국임상수의학회지
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    • 제38권1호
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    • pp.36-40
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    • 2021
  • A 12-year-old dog was referred due to multiple superficial lymphadenopathy. On cytology, each lymph node showed different cell populations where some of them consisted of intermediate to large lymphocytes with frequent Mott cells. Presence of Mott cells along with immature lymphocytes made the cytological diagnosis challenging, and therefore, supplementary diagnostic tests including PCR for Antigen Receptor Rearrangement (PARR) assay and flow cytometry were performed. This case report illustrates the value of flow cytometry in the diagnosis of lymphadenopathy with ambiguous cytologic findings.