• 제목/요약/키워드: Diagnostic multi-level

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당뇨병 환자의 혈당치 측정을 위한 다층 젤라틴 필름을 이용한 진단막의 제조에 관한 기초연구 (Basic Studies on the Preparation of Diagnostic Membranes by Using Multi-Layered Gelatin Films to Measure Blood Glucose Level of Diabetics)

  • 권석기;음성진
    • 멤브레인
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    • 제8권1호
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    • pp.22-28
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    • 1998
  • 혈중 글루코우즈의 농도를 측정하기 위한 진단막의 제조를 위해 다층 젤라틴 필름이 사용되었다. 혈당치를 얻기위해 glucose dehydrogenase와 diaphorase를 이용하여 다층 젤라틴 필름을 통과하는 글루코우즈의 확산속도를 측정하였다. 글루코우즈의 최대 확산속도에 미치는 코팅의 간격거리, 효소의 양, 필름의 두께, 그리고 외부 온도의 영향에 대해 조사하였다.

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Development and utility evaluation of new Multi-Leaf Collimator for Diagnostic X-ray Equipment

  • Ji, Hoon;Han, Su Chul;Baek, Jong Hyeun;Lee, Dong Hoon;Park, Seungwoo
    • Journal of Electrical Engineering and Technology
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    • 제13권2호
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    • pp.936-942
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    • 2018
  • The diagnostic multi-leaf collimator preventing unnecessary dose from entering into patients during the diagnostic examination was made in this study. The movement of the entire 50 leaves was embodied with the group of 25 ones thereof configured in a pair facing each other on the left and right of the median line. Dimensions of the length, width, and height of each shielding leaf were $5{\times}0.5{\times}0.5cm^3$ resulting in the maximum boost field of $10{\times}10cm^2$. The material of multi-leaf collimator had the excellence on the machinability with the use of the SKD-11 alloy tool steel having the high wear resistance against frequent movement, and it was devised to control both-side's shielding leaves by moving 2 motors unlike existing remedial multi-leaf collimator that use as many motors as the number of 50 shielding leaves. Thereafter, the transmission dose of leaves, cross-leaf leakage dose, and inter-leaf leakage dose were measured by the developed multi-leaf collimator attached to X-ray equipment. An ionization chamber was used to detect doses there from, and the comparative analysis was carried out by means of the radiographic film that was easy to detect the dose leakage in between each leaf. Results obtained from the test conducted in comparative analysis yielded approximately 98%, 96%, and 94% of shielding efficiency realized at each level of energy of 80kV, 100kV, and 120kV it was confirmed there was no dose leakage resulted from the varied level of irradiation energy. Thus the multi-leaf collimator to be developed based on this study is thought that it could fully reduce the unnecessary dose to patients in the diagnostic test and the shielding efficiency thereof is expected to be increasing if it is made in a miniaturized form with a way of increasing the thickness of each leaf later for an extended application to general diagnostic purposes.

Multi-level 네트워크의 보안 도메인을 위한 통합 아키텍쳐 설계 및 효율성 측정방법 연구 (A Study for the Designing and Efficiency Measuring Methods of Integrated Multi-level Network Security Domain Architecture)

  • 나상엽;노시춘
    • 디지털산업정보학회논문지
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    • 제5권4호
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    • pp.87-97
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    • 2009
  • Internet network routing system is used to prevent spread and distribution of malicious data traffic. This study is based on analysis of diagnostic weakness structure in the network security domain. We propose an improved integrated multi-level protection domain for in the internal route of groupware. This paper's protection domain is designed to handle the malicious data traffic in the groupware and finally leads to lighten the load of data traffic and improve network security in the groupware. Infrastructure of protection domain is transformed into five-stage blocking domain from two or three-stage blocking. Filtering and protections are executed for the entire server at the gateway level and internet traffic route ensures differentiated protection by dividing into five-stage. Five-stage multi-level network security domain's malicious data traffic protection performance is better than former one. In this paper, we use a trust evaluation metric for measuring the security domain's performance and suggested algorithm.

다층 진단 모델에 의한 광양만의 잔차류 수치 실험 (Numerical simulation of residual currents by diagnostic multi-level model in Kwangyang Bay, Korea)

  • 추효상;이병걸;이규형
    • 한국환경과학회지
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    • 제11권1호
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    • pp.41-56
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    • 2002
  • In order to estimate the quantitative roles of the tide induced residual currents, density currents and wind driven currents on the residual currents in Kwangynag Bay Korea, numerical experiments with a diagnostic multi-level model were carried out. Density currents were calculated from the temperature and salinity data observed in January, May, August and November 1998. Anti-clockwise circulations are formed at the western inner part of the bay, the location from the east of Myodo Is. to the south of POSCO Co. and the place between Yeosu peninsula and Namhae Is. from the calculation results of the tide induced residual currents. Velocities of the density currents are less than 3cm/s at the western inner part of the bay and about 5cm/s at the southern entrance of the bay. Density currents get strong in summer and weak in autumn. Wind driven currents at the surface layer flow in the directions of the given winds which are the daily mean winds when the temperature and salinity observations are carried out. In the middle and lower layers, however the wind driven currents flow in the opposite direction to the surface currents as supplementary currents. The surface wind driven currents are greater than the tide induced residual currents or the density currents. The calculated residual currents including the tide induced residual currents, density currents and wind driven currents agree with the results of the current observations approximately. In the Bay, the wind driven currents affect on the residual currents greatestly and tide induced residual currents and density currents do in the second place and the third place.

인지진단모형을 활용한 수학 학업성취 결과 분석 -2011년 국가수준 학업성취도 평가 자료를 중심으로- (The Analysis of Students' Mathematics Achievement by Applying Cognitive Diagnostic Model)

  • 김희경;김부미
    • 대한수학교육학회지:학교수학
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    • 제15권2호
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    • pp.289-314
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    • 2013
  • 본 연구는 2011년 학업성취도 평가 결과를 Fusion 모형이라는 인지진단모형을 적용하여 수학교과에서 학교급별, 성취수준별, 성별에 따른 인지요소 숙달 양상과 다문화가정의 인지요소 숙달 양상을 분석하였다. 연구결과, 초6은 12개의 인지요소에서 '귀납적으로 추론하기', 중3은 10개의 인지요소에서 '연역적으로 정당화하기', 고2는 10개의 인지요소 중 '사칙계산'이 가장 높은 숙달 비율을 보였다. 성취수준별로 인지요소의 숙달 양상을 분석한 결과, 초 중 고 모두 우수학력 집단은 전체 인지요소에서 94%이상의 숙달률을 보였으나, 기초학력이하 집단 학생들은 거의 모든 인지요소에서 초6과 중3의 경우 미숙달 비율이 70%이상이었고 고2는 99%이상이었다. 또한, 초6, 중3까지는 전반적으로 여학생의 인지요소 숙달 비율이 남학생보다 높으나 고2에서는 대부분의 인지요소에서 남학생이 여학생보다 숙달 비율이 높게 나타났다. 다문화가정 학생 집단과 일반가정 학생 집단 간 인지요소의 숙달 양상은 학교급별로 상이하게 나타났다.

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유연매체 이송 시스템의 고장 진단을 위한 Simulation (Simulation for Automatic Diagnosis of Defect in Media Transport System)

  • 이남훈;유상헌;구자춘;최연선
    • 한국소음진동공학회:학술대회논문집
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    • 한국소음진동공학회 2005년도 추계학술대회논문집
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    • pp.564-568
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    • 2005
  • As functional requirements of automatic office machines like printers, ATMs, copying machines are on a trend for the higher speed and precision, extensive technical advances are being developed and implemented in the industry. Media transport system is a device to convey a sheet of paper in ATMs and printers. The stability of media transport system is a matter of concern as their operating throughput rapidly increases. And defects of belts or rollers in a transport system directly affect the level of stability of the system. Therefore an automatic diagnostic system for predicting various defects is necessary for the stable operation of the media transport system. A simulation based on multi-body dynamics has been done for a feasibility study of a system design for the defect anticipation.

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디지털 유방영상에서 멀티영상 기반의 컴퓨터 보조 진단에 관한 연구 (A Study on the Multi-View Based Computer Aided Diagnosis in Digital Mammography)

  • 최형식;조용호;조백환;문우경;임정기;김인영;김선일
    • 대한의용생체공학회:의공학회지
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    • 제28권1호
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    • pp.162-168
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    • 2007
  • For the past decade, the full-field digital mammography has been widely used for early diagnosis of breast cancer, and computer aided diagnosis has been developed to assist physicians as a second opinion. In this study, we try to predict the breast cancer using both mediolateral oblique(MLO) view and craniocaudal(CC) view together. A skilled radiologist selected 35 pairs of ROIs from both MLO view and CC view of digital mammogram. We extracted textural features using Spatial Grey Level Dependence matrix from each mammogram and evaluated the generalization performance of the classifier using Support Vector Machine. We compared the multi-view based classifier to single-view based classifier that is built from each mammogram view. The results represent that the multi-view based computer aided diagnosis in digital mammogram could improve the diagnostic performance and have good possibility for clinical use to assist physicians as a second opinion.

당뇨병 진단을 위한 젤라틴 진단막에 관한 연구(1) 온도와 습도가 글루코우즈의 확산 조절에 미치는 영향 (Studies on the Multi-Layered Gelatin Diagnostics Membranes for Diabetes(1) : Effects of Temperature and Humidity on the Diffusion-Controlled Rates of Glucose)

  • 권석기;이병철
    • 멤브레인
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    • 제9권2호
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    • pp.126-131
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    • 1999
  • 당뇨병 환자의 혈당치 측정을 위하여 다층젤라틴 필름으로 만들어진 진단막을 제조하였다. 플라즈마와 혈액 속의 글루코우즈의 농도 변화에 따른 최대확산속도를 측정하였다. 여러 가지 온도에서 3일, 2주, 4주 보관후 온도가 글루코우즈의 확산속도에 미치는 영향을 조사하였다. 다층 젤리탄 진단막의 안정성을 상대습도 80%에서 측정하였다.

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Exonic copy number variations in rare genetic disorders

  • Man Jin Kim
    • Journal of Genetic Medicine
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    • 제20권2호
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    • pp.46-51
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    • 2023
  • Exonic copy number variation (CNV), involving deletions and duplications at the gene's exon level, presents challenges in detection due to their variable impact on gene function. The study delves into the complexities of identifying large CNVs and investigates less familiar but recurrent exonic CNVs, notably enriched in East Asian populations. Examining specific cases like DRC1, STX16, LAMA2, and CFTR highlights the clinical implications and prevalence of exonic CNVs in diverse populations. The review addresses diagnostic challenges, particularly for single exon alterations, advocating for a strategic, multi-method approach. Diagnostic methods, including multiplex ligation-dependent probe amplification, droplet digital PCR, and CNV screening using next-generation sequencing data, are discussed, with whole genome sequencing emerging as a powerful tool. The study underscores the crucial role of ethnic considerations in understanding specific CNV prevalence and ongoing efforts to unravel subtle variations. The ultimate goal is to advance rare disease diagnosis and treatment through ethnically-specific therapeutic interventions.

개에서 컴퓨터단층촬영술을 이용하여 진단한 임상증상이 없는 간외성 전신문맥단락의 영상학적 평가 (Diagnostic Imaging Features of Asymptomatic Extrahepatic Portosystemic Shunt Detected by CT in Dogs)

  • 최수영;이인;최호정;이영원
    • 한국임상수의학회지
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    • 제30권4호
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    • pp.273-277
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    • 2013
  • This study was performed to compare clinical and diagnostic imaging features between asymptomatic and symptomatic extrahepatic portosystemic shunts in dogs. The data of thirty patients diagnosed with extrahepatic PSS by multi-detector CT were reviewed, and the dogs were divided into asymptomatic (9/30) and symptomatic (21/30) groups. Signalments, hematologic results, liver size, morphologic classifications and main portal vein to abdominal aortic ratio (PV/AO) at the porta hepatis level from CT images were evaluated in two groups. Shih-tzu (5/9) was the most frequent breed in asymptomatic group, and various breeds were presented in symptomatic group. Mean age of asymptomatic group ($9.2{\pm}3.2$ years) was significantly higher than that of symptomatic group ($4.5{\pm}3.2$ years). The most morphologic form of shunt vessel was the splenophrenic shunt (16/30). PV/AO of asymptomatic group ($1.1{\pm}0.19$) was significantly higher than the values of symptomatic group ($0.55{\pm}0.19$). Clinical signs, hematologic results and diagnostic imaging findings of asymptomatic PSS are too nonspecific to suspect PSS. Therefore, considering of patient's age and CT examination with application of PV/AO ratio could be useful for the diagnosis of asymptomatic PSS.