• Korean Journal of Radiology
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• 제24권10호
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• pp.1006-1016
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• 2023

Objective: Computed tomography (CT) is an established method for the diagnosis, staging, and treatment of multiple myeloma. Here, we investigated the potential of photon-counting detector computed tomography (PCD-CT) in terms of image quality, diagnostic confidence, and radiation dose compared with energy-integrating detector CT (EID-CT). Materials and Methods: In this prospective study, patients with known multiple myeloma underwent clinically indicated whole-body PCD-CT. The image quality of PCD-CT was assessed qualitatively by three independent radiologists for overall image quality, edge sharpness, image noise, lesion conspicuity, and diagnostic confidence using a 5-point Likert scale (5 = excellent), and quantitatively for signal homogeneity using the coefficient of variation (CV) of Hounsfield Units (HU) values and modulation transfer function (MTF) via the full width at half maximum (FWHM) in the frequency space. The results were compared with those of the current clinical standard EID-CT protocols as controls. Additionally, the radiation dose (CTDIvol) was determined. Results: We enrolled 35 patients with multiple myeloma (mean age 69.8 ± 9.1 years; 18 [51%] males). Qualitative image analysis revealed superior scores (median [interquartile range]) for PCD-CT regarding overall image quality (4.0 [4.0-5.0] vs. 4.0 [3.0-4.0]), edge sharpness (4.0 [4.0-5.0] vs. 4.0 [3.0-4.0]), image noise (4.0 [4.0-4.0] vs. 3.0 [3.0-4.0]), lesion conspicuity (4.0 [4.0-5.0] vs. 4.0 [3.0-4.0]), and diagnostic confidence (4.0 [4.0-5.0] vs. 4.0 [3.0-4.0]) compared with EID-CT (P ≤ 0.004). In quantitative image analyses, PCD-CT compared with EID-CT revealed a substantially lower FWHM (2.89 vs. 25.68 cy/pixel) and a significantly more homogeneous signal (mean CV ± standard deviation [SD], 0.99 ± 0.65 vs. 1.66 ± 0.5; P < 0.001) at a significantly lower radiation dose (mean CTDIvol ± SD, 3.33 ± 0.82 vs. 7.19 ± 3.57 mGy; P < 0.001). Conclusion: Whole-body PCD-CT provides significantly higher subjective and objective image quality at significantly reduced radiation doses than the current clinical standard EID-CT protocols, along with readily available multi-spectral data, facilitating the potential for further advanced post-processing.

• 대한의용생체공학회:의공학회지
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• 제27권5호
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• pp.229-236
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• 2006

The acoustic field analysis method is the superior calibration method for rectifying the ultrasonic probe sensitivity. This method also can be applied to evaluate the probe performance in clinical fields without numerical analysis and precise measurements. In this paper, we propose the method of acoustic field pattern analysis with probe channel division for the evaluation of diagnostic ultrasound probe characterization. In order to verify our purpose, we performed a set of experiments. We measured the acoustic-field pattern of the three inferiority probes by channel division to evaluate an acoustic field distribution and impulse response characteristics. By comparing the results of acoustic field measurement method with that of conventional method such as impulse response and live image test for linear array probes, it is demonstrated that the ultrasound field measurement method is more effective then conventional method in detection of defective elements.

• 한국항만경제학회지
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• 제35권1호
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• pp.97-116
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• 2019

국가산업단지 및 수출입공항 항만은 물류의 주요 결절점으로 물류서비스 용이성은 국내 전체 공급망의 성공적인 운영과 밀접한 관계가 있다. 이에 국가에서는 각 시설에 대한 개발계획을 세워 지속적으로 관리하고 있으나, 명확한 현황진단방법의 부재로 인해 투자 대상의 선정 및 우선순위설정 등에 어려움을 겪고 있는 실정이다. 따라서 원활한 국가물류 및 투자 효율성 확보를 위해서는 국가산업단지, 수출입 공항 및 항만을 대상으로 물류서비스 수준에 대한 현황을 명확히 진단하고 이를 바탕으로 한 지속적인 관리 및 개발이 필요하다. 본 연구에서는 이용자가 인지하는 물류서비스요소와 실제 시설개선 대상인 물류시설요소로 구분되는 물류서비스 현황진단요소 구성안을 도출하였으며 이를 적용하여 실제 시설을 진단하고 부족한 물류서비스요소의 개선을 위한 물류시설요소들의 개선 우선순위를 결정하는 적용방법을 함께 제안하였다. 마지막으로 국가산업단지 3개소, 수출입항만 3개소, 수출입공항 2개소 등 실제 시설에 개발한 진단방법론을 적용함으로써 연구 결과의 활용성을 확인하였다.

• Journal of the Korean Data and Information Science Society
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• 제16권3호
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• pp.665-682
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• 2005

The sample reuse bootstrap technique has been successful to attract both applied and theoretical statisticians since its origination. In recent years a good deal of attention has been focused on the applications of bootstrap methods in regression analysis. It is easier but more accurate computation methods heavily depend on high-speed computers and warrant tough mathematical justification for their validity. It is now evident that the presence of multiple unusual observations could make a great deal of damage to the inferential procedure. We suspect that bootstrap methods may not be free from this problem. We at first present few examples in favour of our suspicion and propose a new method diagnostic-before-bootstrap method for regression purpose. The usefulness of our newly proposed method is investigated through few well-known examples and a Monte Carlo simulation under a variety of error and leverage structures.

• Journal of Power Electronics
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• 제16권4호
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• pp.1415-1425
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• 2016

This paper presents a new approach for fault diagnosis in three-level neutral point clamped inverters. The proposed method is based on the average values of the positive and negative parts of normalized output currents. This method is capable of detecting and locating multiple open-circuit faults in the controlled power switches of converters in half of a fundamental period of those currents. The implementation of this diagnostic approach only requires two output currents of the inverter. Therefore, no additional sensors are needed other than the ones already used by the control system of a drive based on this type of converter. Moreover, through the normalization of currents, the diagnosis is independent of the load level of the converter. The performance and effectiveness of the proposed diagnostic technique are validated by experimental results obtained under steady-state and transient conditions.

• Communications for Statistical Applications and Methods
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• 제20권3호
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• pp.217-223
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• 2013

Two influence diagnostic methods for the common mean model are proposed. First, an investigation of the influence of observations according to minor perturbations of the common mean model is made by adapting the local influence method which is based on the likelihood displacement. It is well known that the maximum likelihood estimates are in general sensitive to influential observations. Case-deletions can be a candidate for detecting influential observations. However, the maximum likelihood estimators are iteratively computed and therefore case-deletions involve an enormous amount of computations. An approximation by Newton's method to the maximum likelihood estimator obtained after a single observation was deleted can reduce much of computational burden, which will be treated in this work. A numerical example is given for illustration and it shows that the proposed diagnostic methods can be useful tools.

• 한국유체기계학회 논문집
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• 제12권2호
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• pp.31-38
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• 2009

The valve performance has been evaluated from the theoretical equation based on design information such as packing thrust, spring preload and friction coefficient(${\mu}$). The accuracy of those data can be lower than that of vendor's initial design data. Especially, the friction coefficient can be degraded with time than the original condition and the valve performance calculated using the previous friction coefficient can not be available. Accordingly, this paper is describing a new performance evaluation method of valve based on diagnostic test data which are acquired from a site valve tested in static and dynamic conditions. Especially, this paper provides a new method using friction coefficient(${\mu}$) which is derived from the diagnostic test data acquired in the valve's design basis condition.

• 대한기계학회논문집A
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• 제30권9호
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• pp.1154-1159
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• 2006

In this paper, time-frequency analysis and multi-dimensional spectral analysis methods are applied to source identification and diagnostic of non-stationary sound vibration signals. By checking the coherences for concerned time, this simulation is very well coincident to expected results. The proposed method analyzes the signal instantaneously in both time and frequency domains. The MDSA (Multiple Dimensional Spectral Analysis) analyzes the signal in the plane of instantaneous time and instantaneous frequency at the same time. And it was verified by using the 1500cc passenger car which is accelerated from 70Hz to 95Hz in 4 seconds, the proposed method is effective in determining the vehicle diagnostic problems.

• Nuclear Engineering and Technology
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• 제53권7호
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• pp.2133-2150
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• 2021

In this work, Esfahan light water subcritical reactor (ELWSCR) is analysed using experimental and theoretical diagnostic methods. Important neutronic parameters of the system such as prompt neutron lifetime, delayed neutron fraction, prompt neutron decay constant, negative reactivity of the core, fuel and moderator temperature coefficient of reactivity, and overall and local void coefficient of reactivity are estimated. Also, neutron flux distribution, reflector saving, water level effect, and lattice pitch of the core including operating point of the facility are studied in details. Theoretical results are calculated by MCNPX and measurements are performed utilizing zero power reactor noise method. Detailed descriptions of the results are explained in the text.

• 한국수산과학회지
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• 제51권1호
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• pp.23-30
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• 2018

Kudoa septempunctata, a myxosporean parasite that infects olive flounder Paralichthys olivaceus is known to cause Kudoa food poisoning. Entire trunk muscle (ETM) is used for diagnosis of the parasite in fish and this method demands sacrifice of the host, causing a loss of commercial value. We developed a non-destructive method that uses a plastic syringe-style implanter to draw the sample, called the part-point muscle (PPM) sampling technique. We validated the PPM method in fish infected with K. septempunctata at the level detectable by the ETM method. We confirmed that the PPM method is equally sensitive in comparison to the ETM method for diagnosing K. septempunctata spores in olive flounder muscle. Our study also confirmed that the parasite is uniformly distributed in the dorsal muscle of infected fish. Over a period of 1 month, we observed no mortality of the host fish used for sampling by the PPM method. Thus, our studies demonstrate that the PPM sampling technique is an efficient, non-destructive method for diagnosing K. septempunctata in olive flounder.