• Title/Summary/Keyword: Diagnostic Possibility

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The Clinical Usefulness of Ultrasound-Guided Fine Needle Aspiration Cytology in Thyroid Nodules (갑상선 결절에서 초음파 유도 미세침흡인검사의 임상적 유용성)

  • Kim, Mi-Young;Park, Young-Sun
    • Journal of radiological science and technology
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    • v.31 no.2
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    • pp.141-147
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    • 2008
  • Thyroid nodules are a common disease in clinical practice. Fine needle aspiration (FNA) is an accurate and safe method for the diagnosis of thyroid nodules. One of the limitations of FNA is the variable rate of unsatisfactory specimens, especially in small sized, deep seated or complex cystic nodules. To overcome this problem, ultrasound-guided FNA (US-FNA) has been widely used. In this study, the clinical usefulness of US-FNA cytology in thyroid nodules was investigated. Female to male ratio was 6.58:1. The incidence of nodules were 157 (43.1%) cases on the right, 130 (35.7%) cases on the left and 9 (2.5%) cases in isthmus. Total 139 cases (38.2%) belong to less than 1cm and 225 cases (61.8%) belong to more than 1cm. As for the echo type in the nodules, solid types were 255(70.1%), cystic type 39 (10.7%) cases, and the percentage of mixed type was 19.2%. The results show that US-FNA reduces the possibility of unsatisfactory cytologic specimens and the rate of false-negative diagnosis, and improves the diagnostic accuracy in investigation thyroid nodules.

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Saliva-Based Screening of High-Risk Human Papillomavirus Strains: Detection in Female Indonesian and Thai Dental Students

  • Wimardhani, Yuniardini Septorini;Sasanti, Harum;Wardhany, Indriasti Indah;Sarsito, Afi Savitri;Pradono, Siti Aliyah;Subita, Gus Permana;Soegyanto, Anandina Irmagita;Rahmayanti, Febrina;Chamusri, Nutchapon;Iamaroon, Anak
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.13
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    • pp.5525-5529
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    • 2015
  • Background: Currently it is believed that human papillomaviruses (HPV) are associated with the development of some oral/oropharyngeal cancers. It has been suggested that these viruses influence carcinogenesis in both smokers and non-smokers. Data on the prevalence of HPV in healthy adults are thus needed to estimate the risk of oral/oropharyngeal cancer. The aim of this study was to assess the prevalence of oral HPV in healthy female adults in Indonesia and Thailand. Materials and Methods: Healthy female students from the Faculties of Dentistry of Universitas Indonesia and Chiang Mai University were asked to participate in this pilot study. DNA was extracted from saliva specimens and screened for HPV16 and HPV18 using PCR. Results: The age, marital status and sexual experience of the subjects between the two countries were not significantly different. Eight (4%) and 4 (2%) samples were positive for HPV16 and HPV18, respectively. Fisher's Exact test found a significant difference between HPV16 positivity in subjects who were married and had sexual intercourse but not for HPV18. Conclusions: This study successfully detected presence of HPV16 and HPV18 DNA in a number of saliva samples from female dental school students. Marital status, experience of sexual intercourse and safe sexual practice are related to the possibility of finding HPV DNA finding in saliva. Dentists, physicians and other health care professionals may gain significant value from the findings of this study, which provide an understanding of the nature of HPV infection and its risk to patient health and disease.

A Study in Preparation of $^{113m}In$ colloid as Scanning Agent and it's Organ Distribution in Rats (주사용(走査用) $^{113m}In$ 교질(膠質)의 조제(調製) 및 흰쥐에서의 장기분포(臟器分布)에 관(關)한 연구(硏究))

  • Koh, Chang-Soon;Rhee, Chong-Heon;Chang, Ko-Chang;Hong, Chang-Gi D.
    • The Korean Journal of Nuclear Medicine
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    • v.3 no.1
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    • pp.73-82
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    • 1969
  • The newly developed diagnostic method with application of $^{113}Sn-^{113m}In$ cow system ($^{113}Sn:\;T\frac{1}{2}$ 118 days, $^{113m}In:\;T\frac{1}{2}$ 1.7 hrs, 390 Kev, Single ${\gamma}$) has the remarkable advantages such as increased diagnostic ability by single large dose administration of $^{113m}In$ with no subsequent radiation hazard and shortened examining time. We reformed the research of following scope with the use of developed $^{113}Sn-^{113m}In$ cow (25 mCi) generator: The sizes of particles produced under various conditions were investigated, and possibility for application to the scannings of various organs such as brain, liver, lung, bone marrow and blood pool etc. were studied. Results: $^{113m}InCl_3$ solution eluted from diluted HCl solution (pH 1.5) passed through $^{113}Sn-^{113m}In$ generator, and there can be produced various sized particles of colloidal indium. And there observed the state of distribution of $^{113m}In$ in each organ which showed many differences according to the particle sizes of colloidal indium. The results are stated as follows: 1. The adjustment of pH is the most important factor in making the desirable particle size of colloidal indium. The colloid for blood pool showed the highest level as 7.1%/gm blood, at pH 1.7, the colloid of pH 3.5 for liver scanning showed the highest level, 88.4%, in the liver, the colloid pH 6 showed the highest level, 3.1%, in the spleen, and the colloid of pH 11.0 showed the highest level, 85.3%/gm, in the lung. 2. The colloid for liver scanning made with NaCl-NaOH system showed the highest liver uptake at pH 7.2, and at either higher or lower pH than 7.2 showed decrease of liver uptake more or less. 3. The activity of $^{113m}In$ eluted through $^{113}Sn-^{113m}In$ generator indicated over 90% in the initial 4 ml, and particularly 88.1%-86.0% in the initial 2 ml. 4. The incubation time, tempertaure and mechanical irritation related to colloid formation and coating of colloid were not the definite condition of influence.

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A Trend Analysis on Mathematics Underachievers in the Elementary School (초등학교 수학 학습 부진 발생 경향 분석)

  • Park, Ju Gyoung;Oh, Youngyoul
    • Journal of Elementary Mathematics Education in Korea
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    • v.17 no.2
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    • pp.265-283
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    • 2013
  • This research puts the purpose in examining the general trend of mathematics underachievers in the elementary school based on the analysis results of mathematics diagnostic assessment of mathematics underachievers and the recognition of teachers and students. To achieve research questions, this research analyzed the results of diagnostic assessment of mathematics underachievers from the third grade to the sixth grade of two elementary schools, Seoul, carried out in March, 2010. Results were classified according to grades and genders. Each analysis was performed under the standards of frequency and frequency level. Secondly, questionnaires were conducted, and general trend of mathematics underachievers were analyzed. Conclusion based on research results above can be drawn as follows: Firstly, as a result of analyzing the general trend of mathematics underachievers in the elementary school, mathematics underachievers appeared to be accumulated and intensified as their grade is ascended. Therefore, support and encouraging students to experience mathematics positively and successfully from the elementary school is needed. In addition, to prevent the accumulation of learning deficiency, preventive measures should be taken from the lower grades. Secondly, the possibility of accumulating learning deficiency due to the selection method in deciding underachieving only with total scores should not be disregarded. Therefore, since the accumulation of learning deficiency can be worked as a new factor of learning underachieving, the amendment of teaching methods in learning underachieving based on objective data analysis is required. Thirdly, teachers and students recognized that the learner is the main factor of mathematics underachieving. This indicates that mathematics learning difficulty is improved through the education of learners. Therefore, studies on mathematics underachievers should be activated, and the effective education program should be developed.

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Clinical Evaluation of Surgical Treatment for Hemoptysis Patients (객혈환자의 외과적 처치에 대한 임상적평가)

  • 이성주;문승철
    • Journal of Chest Surgery
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    • v.30 no.11
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    • pp.1097-1104
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    • 1997
  • The expectoration of blood is always a fearful experience for the patient and a matter of grave concern to the attending physician, because it may be the warning sign of serious diseases. When such bleeding occurs, the possibility of its being due to pulmonary tuberculosis, bronchiectasis or carcinoma of the lung is promptly suggested. Nowadays, with the advance of modern diagnostic studies, differential diagnosis has become possible for the hemoptysis patients to have appropriate treatment. This evaluation is based on the review of 75 cases of patients whom we performed emergency open thoracotomies for 6 years from March 1992 to February 1997 in the Department of Thoracic and Cardiovascular Surgery, Seoul Adventist Hospital. The mean age of the patients was 36.6 years old with a range from 19 to 68, and most prevalent age group was thirties. The most common underlying lung disease causin hemoptysis was tuberculosis(44%). Most accurate diagnostic study was bronchoscopy during hemoptysis(95 Vo) and right middle & lower lobe(17.3%) was the most common site of lesion. Lobectomy(50%) was the most frequent operative method and recurrent hemoptysis(31.6%) was the most common postoperative complication. But most of the patients(82.6%) were completely recovered by surgical treatment. Now we concluded that the proper management of hemoptysis was completed by surgical approach with definite diagnosis and supportive medication.

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Research on Vehicle Diagnostic and Monitoring technology Using WiBro Portable Device (와이브로 휴대기기를 사용한 차량진단 및 모니터링 기술에 관한 연구)

  • Ryoo, Hee-Soo;Won, Yong-Gwan;Park, Kwon-Chul;Ahn, Yong-Beom
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.47 no.10
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    • pp.17-26
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    • 2010
  • This is concerned with the technology to monitor the vehicle operation, failure and disorder by using WiBro portable device. More precisely, the technology makes it possible that the information collection device is connected to both ECU(Electronic Control Unit) which is the device for controlling engine, transmission, brake, air-bag, etc that are connected to in-vehicle network and OBD-II connector that is for data collection from various sensors. In addition, with a WiBro portable device (cell phone, PDA, PMP, UMPC, etc). equipped with a vehicle diagnostic programs, information for operation, failure and malfunction can be obtained and analyzed in real-time, and alarm is alerted when the vehicle is in abnormal status, which makes the early reactions to the status. Furthermore, the collected data can be sent through WiBro network to the server managed by the company specialized in managing the vehicles, thus the technology could help the drivers who have less knowledge about their auto-vehicles have safe and economic driving. There is always a possibility of malfunction due to various types of noise that are caused by wring-harness when the device is wired-connected. In this research, in order to overcome this problem, we propose a system configuration that can do monitoring and diagnosis with a device for collecting data from vehicle and a personal WiBro device. Also, we performed research on data acquisition and interlock for the system defined by the definition for information and data sharing platform.

Ex Vivo Raman Spectroscopy Measurement of a Mouse Model of Alzheimer's Disease (라만 기반 치매 모델의 뇌조직 분광 특성 측정)

  • Ko, Kwanhwi;Seo, Younghee;Im, Seongmin;Lee, Hongki;Park, Ji Young;Chang, Won Seok;Kim, Donghyun
    • Korean Journal of Optics and Photonics
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    • v.33 no.6
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    • pp.331-337
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    • 2022
  • Raman spectroscopy is an optical technique that can identify molecules in a label-free manner, and is therefore heavily investigated in various areas ranging from biomedical engineering to materials science. Probe-based Raman spectroscopy can perform minimally invasive chemical analysis, and thus has potential as a real-time diagnostic tool during surgery. In this study, Raman experimentation was calibrated by examining the Raman shifts with respect to the concentrations of chemical substances. Raman signal characteristics, targeted for normal mice and cerebral tissues of the 5xFAD dementia mutant model with accumulated amyloid beta plaques, were measured and analyzed to explore the possibility of diagnosis of Alzheimer's disease. The application to the diagnosis of dementia was cross-validated by measuring Raman signals of amyloid beta. The results suggest the potential of Raman spectroscopy as a diagnostic tool that may be useful in various areas of application.

Effect of epidural corticosteroid injection on magnetic resonance imaging findings

  • Kim, Min Soo;Jeong, Tae Yoon;Cheong, Yu Seon;Jeon, Young Wook;Lim, So Young;Kang, Seong Sik;Kim, In Nam;Chang, Tsong Bin;Seong, Hyun Ho;Hwang, Byeong Mun
    • The Korean Journal of Pain
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    • v.30 no.4
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    • pp.281-286
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    • 2017
  • Background: Magnetic resonance imaging (MRI) of the spine is the preferred diagnostic tool for pathologic conditions affecting the spine. However, in patients receiving epidural corticosteroid injection (ESI) for treatment of spinal diseases, there is a possibility of misreading of MR images because of air or fluid in the epidural space after the injection. Therefore, we defined the characteristics of abnormal changes in MRI findings following an ESI in patients with low back pain. Methods: We reviewed the medical records of 133 patients who underwent MRI of the lumbar spine within 7 days after ESI between 2006 and 2015. All patients were administered an ESI using a 22-gauge Tuohy needle at the lumbar spine through the interlaminar approach. The epidural space was identified by the loss of resistance technique with air. Results: The incidences of abnormal changes in MRI findings because of ESI were 54%, 31%, and 25% in patients who underwent MRI at approximately 24 h, and 2 and 3 days after ESI, respectively. Abnormal MRI findings included epidural air or fluid, needle tracks, and soft tissue changes. Epidural air, the most frequent abnormal finding (82%), was observed in 41% of patients who underwent MRI within 3 days after injection. Abnormal findings due to an ESI were not observed in MR images acquired 4 days after ESI or later. Conclusions: Pain physicians should consider the possibility of abnormal findings in MR images acquired after epidural injection using the interlaminar approach and the loss of resistance technique with air at the lumbar spine.

THE EVALUATION OF SELLA TURCICA ON THE SHAPE AND VOLUME IN CLASS III PATIENTS : The Possibility of Sella Turcica as Class III Growth Prediction Indicator (성인 III급 부정교합자의 SELLA TURCICA의 형태 및 크기에 관한 연구 : SELLA TURCICA부피의 III급 부정교합 예측 지표로서의 가능성)

  • Yang, Won-Sik;Ha, Tai-Heon
    • The korean journal of orthodontics
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    • v.28 no.2 s.67
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    • pp.203-217
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    • 1998
  • Sella turcica contains pituitary gland that has influence on craniofacial growth. So, if the volume of sella turcica correlate to the function of Pituitary gland, we can assume that the volume of sella turcica in skeletal Class III patients has some difference to that of normal occlusion group. The purpose of this study was to evaluate the difference of shape and volume of sella turcica between normal occlusion group and Class III patients. The shape of sella turcica was Classified by Inaba method and the volume of sella turcica was measured in lateral and P-A cephalograms by Di Chiro method. To find out the possibility of the volume of sella turcica as diagnostic aid to predict Class III growth pattern, the correlation coefficients between the volume of sella and cephalometric variables were calculated. The results were as follows. 1. The volume of sella turcica in Class III patients is larger than that of normal occlusion groups 2. The volume of sella turcica in female was larger than that of male in Class III patients 3. The volume of sella turcica has close correlation with APDI, ANB, SNA, SNB, ODI, gonial angle, post. cranial base length 4. Sella Index (volume of sella / ant. cranial base length) can be a more accurate indicator that represent Class III growth pattern than volume of sella itself. 5. The morphologic pattern of sella turcica had no significant difference between two groups.

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Development of a Diagnostic Index on the Approach of Typhoon Affecting Korean Peninsula (한반도에 영향을 주는 태풍의 접근 진단 지수 개발)

  • Choi, Ki-Seon;Kim, Tae-Ryong
    • Journal of the Korean earth science society
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    • v.32 no.4
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    • pp.347-359
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    • 2011
  • This study has developed the index for diagnosis on possibility that typhoons (TYs) affect Korea. This index is closely related to the strength of the western North Pacific high (WNPH), which is calculated as a difference in meridional wind between at the highest correlation area (around Korea) and at the lowest correlation area (sea southeast of Japan) through a correlation analysis between TC frequency that affects Korea and 500 hPa meridional wind. In low frequency years that selected from Korea affecting TC index, anomalous northeasterly is strengthened from Korea to the South China Sea because the center of anomalous anticyclonic circulation is located to northwest of Korea. Thus, TCs tend to move westward from the sea east of the Philippines to the mainland China. On the other hand, in high frequency years, anomalous southwesterly serves as steering flow that more TCs move toward Korea because the center of anomalous anticyclonic circulation is located to sea east of Japan. Consequently, this study suggests that if this index is calculated using real time 500 hPa meridional winds that forecasted by dynamic models during the movement of TCs, the possibility that TCs approach Korea can be diagnosed in real time.