• Title/Summary/Keyword: Diagnostic Pattern

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Cytologic Features of Well Differentiated Hepatocellular Carcinoma (분화도가 높은 간세포암종의 세침흡인 세포학적 소견 - 비종양성 병변과의 감별 -)

  • Khang, Shin-Kwang;Lee, Seung-Sook;Cho, Kyung-Ja;Ha, Hwa-Jeong
    • The Korean Journal of Cytopathology
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    • v.8 no.1
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    • pp.1-10
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    • 1997
  • The fine needle aspiration biopsy(FNAB) has become a popular method to diagnose mass lesions of the liver. Although many reports have listed FNAB criteria to be used to diagnose hepatocellular carcinoma(HCC), a diagnostic dilemma still exists at the extreme ends of the spectrum, particularly for well differentiated HCC. The authors reviewed a series of FNAB specimens of the liver to distinguish well differentiated HCC from nonneoplastic liver. Fifteen cytologic features were examined in this study: high cellularity, large sheet formation, trabecular pattern, acinar pattern, dispersed pattern, irregular arrangement, increased nuclear/cytoplasmic ratio, naked nuclei, irregular chromatin, irregular nuclear contour, multinucleation, uniform macronucleoli, multiple nuclei, uniform small cytoplasm and monotony of atypia. These features were examined in a series of 76 FNAB specimens. Fifty two specimens were from patients with HCC and 24 specimens were from patients with nonneoplastic lesion or tumors other than HCC containg adequate amount of nonneoplastic hepatocytes in smear. All specimens were coded as to the presence or absence of the above cytologic features. With the use of step-wise logistic regression analysis, three features were identified as the key cytologic features predictive of HCC: irregular chromatin, monotony of atypia and absence of large sheet formation. When these criteria were used, the sensitivity diagnosing HCC by FNAB was 94.2%, specificity 100%, positive predictive value 100% and negative predictive value was 88.9%.

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Spiral Structure and Mass Inflows in Barred-Spiral Galaxies

  • Kim, Yonghwi;Kim, Woong-Tae
    • The Bulletin of The Korean Astronomical Society
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    • v.38 no.2
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    • pp.39.1-39.1
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    • 2013
  • We use high-resolution hydrodynamic simulations to study nonlinear gas responses to imposed non-axisymmetric stellar potentials in barred-spiral galaxies. The gas is assumed to be infinitesimally thin, isothermal, and unmagnetized. We consider various spiral-arm models with differing strength and pattern speed, while fixing the bar parameters. We find that the extent and shapes of spiral shocks as well as the related mass drift depend rather sensitively on the pattern speed. In models where the arm pattern is rotating more slowly than the bar, the gaseous arms extend from the bar ends all the way to the outer boundary, with a pitch angle slightly smaller than that of the stellar counterpart. The arms drive mass inflows at a rate of ${\sim}0.5-2.5M{\odot}/yr$ to the bar region to which the shock dissipation, external torque, and self-gravitational torque contribute about 50%, 40%, and 10%, respectively. About 85% of the inflowing mass is added to bar substructures such as an inner ring, dust lanes, and a nuclear ring. while the remaining 15% encircles the bar region. On the other hand, models where the arms corotate with the bar exhibit mass outflows, rather than inflows, over most of the arm region. In these models, spiral shocks are much more tightly wound than the stellar arms and cease to exist in the region where $M{\bot}/sinp*{\geq}25-40$, where $M{\bot}$ denotes the Mach number of a rotating gas perpendicular to the arms with pitch angle p*. We demonstrate that the distributions of line-of-sight velocities and densities can be a useful diagnostic tool to distinguish if the arms and bar corotate or not.

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Corelationship Study between Hwa-Byung and Type A Behavior Pattern, Cardiovascular Disease (화병과 A형 행동유형 및 심혈관질환과의 관련성 연구)

  • Jeong, Ha-Ryong;Koh, Sang-Baek;Park, Jong-Ku;Yu, Jun-Sang;Kong, Kyung-Hwan;Lee, Jae-Hyok
    • Journal of Oriental Neuropsychiatry
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    • v.22 no.2
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    • pp.27-37
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    • 2011
  • Objectives : The purpose of this research is to investigate the corelationship between Hwa-Byung and type A behavior pattern (TABP), cardiovascular disease. Methods : 637 people participated in the community based cohort study in Wonju City of South Korea from July 2nd to August 30th in 2006. Educated investigators checked up EKG and surveyed Hwa-Byung Diagnostic Interview Schedule(HBDIS), Framingham Type A Pattern Score(FTA score). Collected data were analyzed by the chi-square test & t-test. Results : 1. TABP, Hwa-Byung group was 24(70.6%), non Hwa-Byung group was 288(27.8%) p-value was 0.016. Difference of the two group was valid. 2. FTA score, Hwa-Byung group was $5.77{\pm}2.25$, non Hwa-Byung group was $4.41{\pm}2.30$, p-value was 0.002. Difference of the two group was valid. Conclusions : TABP ratio, FTA score was high in Hwa-Byung group compared with non Hwa-Byung group.

An Iris Detection Algorithm for Disease Prediction based Iridology (홍채학기반이 질병예측을 위한 홍채인식 알고리즘)

  • Cho, Young-bok;Woo, Sung-Hee;Lee, Sang-Ho
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.21 no.1
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    • pp.107-114
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    • 2017
  • Iris diagnosis is an alternative medicine to diagnose the disease of the patient by using different of the iris pattern, color and other characteristics. This paper proposed a disease prediction algorithm that using the iris regions that analyze iris change to using differential image of iris image. this method utilize as patient's health examination according to iris change. Because most of previous studies only find a sign pattern in a iris image, it's not enough to be used for a iris diagnosis system. We're developed an iris diagnosis system based on a iris images processing approach, It's presents the extraction algorithms of 8 major iris signs and correction manually for improving the accuracy of analysis. As a result, PNSR of applied edge detection image is about 132, and pattern matching area recognition presented practical use possibility by automatic diagnostic that presume situation of human body by iris about 91%.

The Development of Instrument of Korean Medical Pattern Identification and Functional Evaluation for Five Organ (한의 오장 변증·평가 설문지 개발을 위한 신뢰도 및 타당도 평가)

  • Jang, Eunsu;Kim, Yunyoung;Park, Yang Chun;Jeon, Ju Hyun;Jung, In-Chul
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.31 no.3
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    • pp.173-181
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    • 2017
  • The aim of this study was to identify the reliability and the validity of Five Organs Questionnaire (FOQ). In this study, 335 data was collected from early adulthood of A-city, D-city and C-city in South Korea from Dec. 2016 to Jan. 2017, and the collected data was analyzed with SPSS 23.0 software. The result showed that the Cronbach's ${\alpha}$ of five organs was 0.775-0.853. The reliabilities of test and retest Intra Correlation Coefficient (ICC) for the five organs were .891-.929 in pattern identification and .874-.930 in functional evaluation, respectively. Each organ was divided by two factors, and the factor loadings of Liver, Heart, Spleen, Lung and Kidney were 52.973%, 54.534%, 57.060%, 53.803%, and 46.337%, respectively. The functional evaluation of five organs was associated with self-rated health status as r was -.443 to -.583(p<.001), and quality of life as r was -.5.17 to -.716(p<.001), respectively. The test-retest diagnostic agreement was 67.2% and Kappa was 0.562. This study revealed that FOQ is a reliable and valid questionnaire.

A Study on Bloodletting Therapy of Huangdineijing (『황제내경(黃帝內經)』의 자락요법(刺絡療法)에 대한 연구)

  • Choi, Back-ryul;Lyu, Jeong-ah
    • Journal of Korean Medical classics
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    • v.29 no.3
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    • pp.13-40
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    • 2016
  • Objectives : The practice of bloodletting therapy has taken place for several millenia all over the world. The therapy is still one of the most popular oriental treatments in Korea. This paper studies bloodletting therapy in Huangdineijing to provide the Korean Medicine doctors with knowledge of the therapy to effectively utilize it in their clinics. Methods : The author studied all of the diseases treated by bloodletting therapy in Huangdineijing, and placed them into three categories: the visceral and bowel diseases, the meridian diseases, and miscellaneous diseases. The author reviewed reference documents that show clinical experiences of using the therapy and the results from the research on the therapy's therapeutic dynamics. Results : The treatment principals such as diagnostic methods, meridian points selection, acupuncture methods, and tools for the bloodletting therapy were provided. Most of the diseases treated by the therapy were identified by the visceral pattern identification or meridian pattern identification except miscellaneous diseases. The characteristics of the diseases treated by the therapy were studied and the diseases were placed into categories such as fever, pain, qi counterflow, first-aid, mental disease, and deep-seated disease. Theoretical basis of the mechanism of bloodletting therapy was drawn from several researches and a number of clinical theses related to bloodletting therapy. Conclusions : Results of this study on bloodletting therapy in Huangdineijing could be a useful knowledge for the Korean medicine doctors to be utilized their clinics. Future studies on this type of therapy should be performed to identify the diseases that may be effectively treated by bloodletting therapy.

Three Cases of Fever Unknown Origin with Lymphoproliferative Features and a Unique Pattern of 18-FDG Uptake on the Fusion PET/CT

  • Yun, Dae-Young;Hong, Young-Hoon;Jung, Yong-Uk;Oh, Myung-Jin;Lee, Choong-Ki
    • Journal of Yeungnam Medical Science
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    • v.25 no.1
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    • pp.64-71
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    • 2008
  • Evaluation of a fever of unknown origin (FUO) is complex. Recently, PET scanning has been approved for screening in FUO evaluation. We treated three cases of FUO associated with increased FDG uptake in the bone marrow of the femur and tibia on the fusion PET/CT; all three had the same pattern of uptake. Bone marrow biopsies revealed mature lymphocyte and histiocyte infiltration and myxoid changes in one case, and cortical bone involvement in another case. The cases were all young females who had fever with neutropenia and relative lymphocytosis that lasted for several weeks and then remitted spontaneously. Even though the results of the studies were not diagnostic, the unique uptake pattern on PET/CT and the histology might be related to the cause of the illness and should be studied further to assess the association with classic FUO.

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Taxonomic Study of genus Sedum and Phedimus (Crassulaceae) in Korea Based on External Morphology (외부형태 형질에 근거한 한국산 돌나물과내 돌나물속과 기린초속의 분류학적 고찰)

  • Moon, Ae-ra;Jang, Chang-gee
    • Korean Journal of Plant Resources
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    • v.33 no.2
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    • pp.116-129
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    • 2020
  • The genus Sedum comprises about 400 taxa with worldwide distribution, and about 20 taxa of the genus Phedimus distributed from Asia to Europe. According to some taxonomists, Phedimus and Sedum are two separate genera of the family Crassulaceae; however, in Korea Phedimus has been treated as a subgenus Aizoon within the genus Sedum. This ambiguous taxonomic treatment of the genus Phedimus needs further confirmation. In the study, we investigated morphological characteristics such as the whole plant height, leaf morphology, and seed coat features of these two genera. We believe that these characters are very important to distinguish Phedimus and Sedum. The result indicated that the seed surface pattern was the most useful diagnostic character. The Sedum had a hexagonal pattern with a single nipple protrusion, whereas the Phedimus had a rectangular pattern with papilla on both ends. The results of this study strongly support the separation of Phedimus from Sedum and thus Phedimus need to be treated as an independent genus.

Study of The Diagnostic Indicators of Deficiency of Eum Pattern Identification In Stroke Patients (중풍환자의 음허변증 진단지표에 관한 연구)

  • Kang, Kyung-Won;Go, Ho-Yeon;Kang, Byeong-Kab;Kim, Jeong-Chul;Go, Mi-Mi;Kim, Bo-Young;Seol, In-Chan;Lee, In;Jo, Hyun-Kyung;Choi, Sun-Mi
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.21 no.6
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    • pp.1655-1659
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    • 2007
  • The purpose of this study was to investigate that which symptoms are adequate indicator of the deficiency of Eum pattern in the stroke patients. In the time period Dec. 2006 to Aug. 2007, 479 patients with a first-ever stroke admitted in the department of Internal Medicine of 12 Oriental Medical Hospitals were included. Patients were hospitalized within 1 months after the onset of stroke. Stroke patients had been interviewed by resident who studied standard operation procedures in Fundamental Study for Standardization and Objectification of Differentiation and Pattern Identification of Syndrome of Oriental Medicine for Stroke. Eum-deficiency patients was confirmed by medical specialist diagnosis, resident diagnosis, case report form analysis without a dissenting voice. Deficiency of Eum group included 65 case, Non Eum group 414 case out of 479 patients. dryness of mouth, short and rapid purse, white face and reddish zygoma, mirror-like tongue were higher among Eum group. Eum and Non Eum patients do not significantly differ in reddened tongue, dryness in tongue, night sweat, palpitation, afternoon tidal heat, palmar heat, sores of the mouth or tongue. This study was insufficiency because sample size is very small. More data from prospective cohort studies will help to Korean Standard Differentiation of the Symptoms and Signs for the Stroke.

Application of Excitation Moment for Enhancing Fault Diagnosis Probability of Rotating Blade (회전 블레이드의 결함진단 확률제고를 위한 가진 모멘트 적용)

  • Kim, Jong Su;Choi, Chan Kyu;Yoo, Hong Hee
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.38 no.2
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    • pp.205-210
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    • 2014
  • Recently, pattern recognition methods have been widely used by researchers for fault diagnoses of mechanical systems. A pattern recognition method determines the soundness of a mechanical system by detecting variations in the system's vibration characteristics. Hidden Markov models (HMMs) and artificial neural networks (ANNs) have recently been used as pattern recognition methods in various fields. In this study, a HMM-ANN hybrid method for the fault diagnosis of a mechanical system is introduced, and a rotating wind turbine blade with a crack is selected for fault diagnosis. The existence, location, and depth of said crack are identified in this research. For improving the diagnostic accuracy of the method in spite of the presence of noise, a moment with a few specific frequencies is applied to the structure.