• 대한미생물학회지
• /
• 제21권1호
• /
• pp.113-120
• /
• 1986

In Korea 8 tsutsugamushi disease patients were reported among the United Nations Forces personnel during 1951-54, but the disease was not known among the native Koreans. In Chinhae, patients with fever, chills, headache and rash were observed in every late autumn to early winter for many years, but etiologic diagnosis was not made. In 1985, there were 34 such patients. The authors were able to determine the disease as tsutsugamushi disease by observing the pathognomic eschar in 4 patients and demonstrating antibodies against Proteus OXK and Rickettsia tsutsugamushi antigens in 21 patients. The patients were mostly females of over 30 years of age. It was considered that most of them contracted the infection while doing farm works or picnic at the outskirts of Chinhae city and the adjacent areas. They were treated with chloramphenicol and no fatalities were observed.

• 종양간호연구
• /
• 제9권1호
• /
• pp.60-66
• /
• 2009

Purpose: The purpose of this study was to analyse the level of sexual function among breast cancer survivors as compared with that among healthy women. Method: A total of 208 women participated in this study: 103 breast cancer survivors attending self-help group and 105 community-residing healthy women in G city. A self-reported questionnaire with the Female Sexual Function Index (FSFI) was used to obtain data. Data were analyzed using the SPSS Win 14.0 $K^+$ for descriptive statistics, t-test, and two-way ANOVA. Results: The sexual function score of breast cancer survivors was significantly lower than that of healthy women, respectively $14.9{\pm}9.9$ and $20.6{\pm}11.1$ (p<0.001). The sexual function of recurrent breast cancer survivors was significantly lower than that of women without recurrence. However, there were no significant differences in the sexual function score according to the cancer stage, period since diagnosis, and types of cancer treatment modality. Conclusion: The findings indicate the importance of sex-related counseling and educational programs to improve the quality of life of breast cancer survivors.

• Journal of Genetic Medicine
• /
• 제18권2호
• /
• pp.121-126
• /
• 2021

Chronic progressive external ophthalmoplegia (CPEO) is a complex slowly progressive mitochondrial disorder characterized by extraocular muscle weakness with or without multisystem involvement. The mainstay of therapy in a patient with CPEO is supportive. However, in moderate cases, surgery might be indicated including surgeries for ptosis and strabismus. In this article, we report a Saudi patient with CPEO due to compound heterozygous variants in the DNA polymerase gamma (POLG) gene c.2246T>C p.(Phe749Ser) and c.1735C>T p.(Arg579Trp), which are classified as pathogenic. Proper diagnosis with genetic testing confirmation is important to guide the management and counsel the patient about the prognosis and the management options. The patient was successfully managed with bilateral frontalis sling and illustrates the importance of surgical intervention to improve vision and cosmetic appearance in patients with CPEO. We emphasize the importance of multidisciplinary care in the management of cases of mitochondriopathy, especially CPEO.

• Child Health Nursing Research
• /
• 제14권3호
• /
• pp.285-294
• /
• 2008

Purpose: This study was done to estimate the prevalence of atopic dermatitis (AD) and its risk factors for AD in children living in the community. Method: Random samples of 10,236 were selected from 43 kindergarten (1,418) and 57 elementary (8,718) students in K city. Data from 1,079 (kindergarten children) and 7,271 (elementary) students were used in the final analysis. The Korean-translated modified version of the International Study of Asthma and Allergies in Childhood (ISSAC) questionnaire was used in this cross-sectional survey. Parents answered the survey questionnaire. Results: The lifetime and last 12-month prevalence of AD were 40.15%; 30.86% in kindergarten children and 33.56%; 25.37% in elementary children. The lifetime and last 12-month prevalence of AD diagnosis were 40.8%; 18.68% in kindergarten children and 34.36%; 12.63% in elementary children. The lifetime prevalence of AD treatment was 25.93% in kindergarten children and 22.07% in elementary children. Multivariate logistic regression analysis revealed that risk factors for AD were age, allergic disease, age of house, carpets, pets. Conclusion: The study suggests that prevalence of AD has increased among children in the community. These data can be used to manage possible risk factors that are predictors of childhood AD.

• International journal of advanced smart convergence
• /
• 제11권4호
• /
• pp.104-119
• /
• 2022

Life safety awareness level diagnosis is necessary for customized safety education and continuous safety awareness. As the starting stage of safety education for each life cycle, a scale that has verified the reliability and validity of high school students' life safety awareness has not yet been developed. In this context, the purpose of this study is to develop and validate the life safety awareness scale of high school students and to analyze interindividual differences. Questionnaire data was collected from April to June 2022 from 834 students in the first, second, and third grades of high schools in △△ city in Jeollabuk-do. A final 25-item scale was developed using the preliminary survey, preliminary test, the main test, descriptive statistical analysis, and exploratory and confirmatory factor analysis. This scale consists of four sub-factors: 'safety prevention', 'safety knowledge', 'safety preparation', and 'safety protection'. Good reliability and validity were verified by analysis of content validity and construct validity. The generalizability of the scale was verified by crossover validation between the search group and the crossover group. Based on the interindividual differences analysis, although there was a difference between genders in life safety awareness, there was no difference by grade level and academic achievement. This study is significant in developing the first valid scale that can measure high school students' life safety awareness and providing the necessity and rationale for life safety education by life cycle considering individual gender differences.

• 대한간호학회지
• /
• 제41권3호
• /
• pp.411-422
• /
• 2011

Purpose: The aim of this study was to clarify the actual condition of elders with dementia who were registered in the Seoul Dementia Management Project. Methods: Data were collected from 5,312 elderly patients with dementia. Demographic included characteristics, comorbidity, and healthy lifestyle habits; data from the Seoul Dementia Management Project. Results: First, demographic characteristics were as follows; mean age at the time of definite diagnosis was 78.0 yr. There were slightly more women (69.3%), and 4.55 yr was the average length of education with 41.4% being illiterate or uneducated patients. Second, there were several comorbidities including hypertension (61.7%), diabetes mellitus (31.8%), hypercholesterolemia (10.2%), heart disease (11.1%), obesity (4.2%), and stroke (21.4%). Third, alcoholic history was found in 11.8% of the patients, and smoking in 9.8%. Regular exercise was done by only 29.1% of the patients with dementia. Finally, significant differences between men and women were found for the following; age, education, medical security, hypertension, diabetes mellitus, stroke, alcoholic consumption, smoking, and regular exercise. Conclusion: Authors expect that the present data will be used for establishment of dementia associated projects and policies.

• Asian Pacific Journal of Cancer Prevention
• /
• 제15권2호
• /
• pp.891-894
• /
• 2014

This study is aimed to investigate the role of paired boxed gene 1 (PAX1) methylation analysis by methylation-sensitive high-resolution melting (MS-HRM) in the detection of high grade lesions in atypical squamous cells cannot exclude high-grade squamous intraepithelial lesion (ASC-H) and compared its performance with the Hybrid Capture 2 (HC2) human papillomavirus (HPV) test. In our study, 130 cases with a diagnosis of ASC-H from the cervical cytological screening by Thinprep cytologic test (TCT) technique were selected for triage. Their cervical scrapings were collected and evaluated by using PAX1 methylation analysis (MS-HRM) and high-risk HPV DNA test (HC2), followed by colposcopy and cervical biopsy. Chi-square test were used to test the differences of PAX1 methylation or HPV infection between groups. In the detection of CIN2+, the sensitivity, specificity, the PPV, NPV and the accuracy of PAX1 MS-HRM assay and high-risk HPV (HR-HPV) tests were respectively 80.6% vs 67.7%, 94.9% vs 54.5%, 83.3%, vs 31.8%, 94.0% vs 84.4%, and 91.5% vs 57.7%. The PAX1 MS-HRM assay proved superior to HR-HPV testing in the detection of high grade lesions (CIN2+) in ASC-H. This approach could screen out the majority of high grade lesion cases of ASC-H, and thus could reduce the referral rate to colposcopy.

• 대한정형도수물리치료학회지
• /
• 제13권1호
• /
• pp.18-25
• /
• 2007

Objective: The Purpose of this study is the factive and descriptive research to identify the factors affecting the functional disability of the chronic low back pain patients. We investigated the effect of ODI by the Questionnaire and questioned an 70 patients who were back pain unit at G university hospital in D city from March to May, 2007. The functional disorder in this study were based on the Oswestry Disability Index(ODI) lower back pain disability questionnaire by fairbank(1980), and these data were proceeded by using SPSS/WIN version 10.0. Result: 1. The functional disorder in accordance with age, gender, academic background, occupation, diagnosis, pain cause, pain experience, treatment duration had no significantly similar difference statistically(p>0.05). 2. The functional disorder in accordance with duration of painful generation had statistically significance(P<0.05). Conclusion: we could verify that duration of painful generation affect on the factors affecting the functional disability of the low back pain patients.

• 대한지역사회영양학회지
• /
• 제5권4호
• /
• pp.608-614
• /
• 2000

The purpose of this study was to evaluate the relative importance among various biological and environmental factors on refractive errors. Various factors such as diseases, health related behavior such as drinking, smoking and exercise, as well as dietary factors were considered as a possible determinant. Surveys of 492 residents over 20 years of age in Kuri city were conducted during 1998. The survey included a refractive error test adopting a autokerato-refractometer, dietary survey using a 24 hour recall method, disease survey including blood and other diagnosis tests, and a health behavior survey using questionnaires with variables of smoking, drinking, and exercise. A stepwise logistic regression analysis was adopted to analyse the relative importance among independent variables of health behaviors, disease, and dietary factors on ametropias. As a result, in the case of myopia, liver dysfunction appeared to be the most important factors followed by the health related behavior of smoking and exercise as the second most important factors. Nutrient factors such as carotene and protein appeared to be the third most important factors. Similar results had been shown in the case of the hyperopia. In summary, liver dysfunction and the health related behaviors of drinking and smoking appeared to be more influential factors on abnormal eye sight of myopia and hyperopia than dietary factors.

• Parasites, Hosts and Diseases
• /
• 제59권3호
• /
• pp.319-324
• /
• 2021

Incidence of tsutsugamushi disease (scrub typhus) caused by Orientia tsutsugamushi, is steadily increasing. It is a mite-borne disease transmitted by chigger mites. In this study, the chigger mites were collected from field small mammals in Hwaseong-si (city), Gyeonggi-do (province), Korea, 2019 and 2020. The field small mammals captured were 56 Apodemus agrarius (94.9%) and 3 Crocidura lasiura (5.1%). A total of 7,531 chigger mites were collected from the captured small mammals. Using PCR test, 153 chigger mite pools were examined and 17 pools were reported positive for O. tsutsugamushi. The O. tsutsugamushi were identified to 5 strains; Jecheon strain was most prevalent, followed by Boryong strain. The other strains were OI011, Taguchi, and Shimokoshi. Collectively, these results provide essential regional information on mite-borne tsutsugamushi disease in the Hwaseong-si, and further contribute to bring awareness and rapid diagnosis for the tsutsugamushi disease.