• Title/Summary/Keyword: Development factor

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Stress Release Zone Around Sub-structure Constructed by Non-open Cut Methods (비개착공법으로 건설된 지하구조물 주변 지반 응력이완영역 규명)

  • Seo, Ho-Sung;Cho, Kook-Hwan
    • Journal of the Korean Society for Railway
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    • v.19 no.4
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    • pp.480-488
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    • 2016
  • For the development of areas around railway lines, subsurface construction using the non-open cut method under the railway has recently been increased. However, when a structure under a railway is constructed, the stress release of the ground is not considered an important factor in the design. In this study, laboratory tests were conducted to determine a zone of stress relaxation. Field tests using an inclinometer were performed to measure the horizontal displacement of the ground during non-open cut construction. The stress release zone and the subgrade stiffness were investigated by numerical analysis. The results of the laboratory tests indicated that the failure zone in the ground was similar to a Rankine's active earth pressure zone. The measured data from the inclinometer in the field tests showed that displacements started when a steel pipe was pushed into the ground. The results of numerical analysis show that lateral earth pressure was also close to Rankine's active earth pressure. The roadbed support stiffness of the soil around the structure decreased to 40% of the original value. The ground around the subsurface structure constructed using nonopen cut methods should be reinforced to maintain the running stability of train.

Detection of Human Papillomavirus and Expression of MHC Class I in Laryngeal Squamous Cell Carcinoma (후두편평세포암종에서 Human papillomavirus의 검출과 주조직적합복합체(Major Histocompatibility Complex: MHC) Class I 발현양상)

  • Oh, Byung-Kwon;Hwang, Chan-Seung;Hong, Young-Ho;Kim, Hoon;Kim, Chun-Gil;Min, Hun-Ki
    • Korean Journal of Bronchoesophagology
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    • v.3 no.1
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    • pp.70-78
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    • 1997
  • The development of preneoplastic and neoplastic squamous cell proliferations of body sites such as the skin, female lower genital tract, and larynx is strongly associated with specific types of human papillomaviruses (HPV). Antitumor $CD^{8+}$ cells recognize peptide antigens presented on the surface of tumor cells by major histocompatibility complex (MHC) class I molecules. The MHC class I molecule is a heterodimer composed of an integral membrane glycoprotein designated the alpha chain and a noncovalently associated, soluble protein called beta-2-microglobulin( $\beta$ -2-m). Loss of $\beta$-2-m generally eliminates antigen recognition by antitumor $CD^{8+}$ T cells. We evaluated the expression of $\beta$-2-m as a potential means of tumor escape from immune recognition and the presence of HPV DNA as a cause of laryngeal squamous cell carcinomas (SCCs). Laryngeal SCCs (n=39) were analyzed for MHC class I expression by immunohistochemistry and for presence of HPV by in situ hybridization technique. The results were as follows : 1) HPV DNA was detected in 10 (25.64%) out of 39 cases in laryngeal squamous cell carcinomas. 2) MHC class I down-regulation (heterogenous and negative expression) in HPV positive lesions was higher than HPV negative lesions. 3) The expression of MHC class I was related to cellular differentiation regardless of T-stage and nodal involvement. In conclusion, HPV was thought to be the etiological factor of SCC of larynx, and we found that the down-regulation of MHC class I was a common phenomenon In laryngeal SCC and may provide a way for tumor cells to escape from immune surveillance.

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Flash Flood Risk Assessment using PROMETHEE and Entropy Method (PROMETHEE와 Entropy 기법을 이용한 돌발홍수 위험도 평가)

  • Lee, Jung-Ho;Jun, Hwan-Don;Park, Moo-Jong;Jung, Jae-Hak
    • Journal of the Korean Society of Hazard Mitigation
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    • v.11 no.3
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    • pp.151-156
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    • 2011
  • Previously most of flood prevention efforts have been made for relatively large watersheds near to channel flow. However, as economical development and the expansion of leisure areas to mountainous region, human casualty by flash flood occurs frequently, requiring additional prevention activity. Therefore, to reduce the damage of human lives and property by flash flood, we develop an assessment method for flash flood occurrence for mountainous areas considering various factors involving it. PROMETHEE(Preference Ranking Organization METHod for Enrichment Evaluations) which is one of the MCDM(Multi-Criteria Decision Making) was adopted to assess the contribution of each factor to the risk of the flash flood in the mountainous area. The main evaluation criteria are classified into three categories, namely, the regional and rainfall characteristics, and geographical features. Also, the Entropy method is used to determine the weight of each evaluation criteria without survey. The suggested method based on PROMETHEE with Entropy method is applied to BongHwa region to verify its applicability. After applied, the method successfully assesses the relative risk of flash flood occurrence of each sub region in the BongHwa region. Out of the seventeen sub-regions, five, seven and five of them are evaluated as high-risk, medium-risk, and low-risk, respectively. To verify the results, we searched the historical data of flash flood and the flash flood had occurred in one of high-risk sub-regions at 2008.

A study for recycling plan of excavated soil and filter cake of slurry shield TBM for road construction (도로공사 이수식 쉴드 TBM 굴착토 및 필터케이크 재활용방안 연구)

  • Nam, Sung-min;Park, Seo-young;Ahn, Byung-cheol
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.24 no.6
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    • pp.599-615
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    • 2022
  • In order to excavate underground tunnel most safely such as Han river, the slurry shield TBM method is applied to cope with face of high water pressure for many metro projects. In downtown subway project most of excavated soil is discharged externally whereas in road construction excavated soil is used as filling materials so it becomes important factor for success of the project. After excavated soil, weathered rock and soft rock are discharged with bentonite through discharge pipe to slurry treatment plant then those soils are separated in separation plant according to those size. Fine grained soil has been discarded together with filter cake but it is not toxic and can be mixed with coarse aggregate in proper ratio so this study is performed to find use of qualified filling material to meet quality standard. Therefore, in this study, legal standards and quality standards for the utilization of excavated soil of the slurry shield TBM method were examined and test was conducted to derive recycling way for filter cake and aggregate. And a plan for using it as a filling material for road construction was derived. Because bentonite is a clay composed of montmorillonite, and the excavated soil in the tunnel is also non-toxic, disposal of this material can waste social cost so it is expected to be helpful in the underground space development project that carries out the TBM project by recycling it as a valuable resource.

Applicability on Wet-land for Management of NPS in Organic Matter and Nutrients from Agriculture and Livestock Farm Area (가축 사육 농업지역 강우유출수 내 유기물 및 영양염류 관리를 위한 인공습지 적용성 평가)

  • Im, Jiyeol;Kang, Chaewon;Gil, Kyungik
    • Journal of Wetlands Research
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    • v.23 no.4
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    • pp.372-380
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    • 2021
  • Non-point source pollutants and high-concentration livestock wastewater are reported as major factor of water pollution in water system and wet-land. So, LID is suggested as a method to manage of them. wet-lands is presented as effective method for management of NPS from agriculture and livestock farm area based on various NPS reduction mechanism. In this research, the application of wet-lands was evaluated based on monitoring and modeling of agriculture and livestock farm in J city, Jeollabuk-do. As a resutl, EMC during rainfall event was found to be about 27 times higher than dry season based on a BOD. indicating that the management of non-point pollutants is urgent. Modeling-based wet-land reduction efficiency was BOD 57.5%, TN 48.9% and Tp 64.2%. However, removal efficiency of wet-land tends to decrease during the winter and large amounts of rainfall runoff occur, it is necessary to manage of wet-land. Based on the results of this research, wet-land could be proposed as an alternative to stable management of NPS in agriculture and livestock farm area.

A Study on Method to prevent Collisions of Multi-Drone Operation in controlled Airspace (관제 공역 다중 드론 운행 충돌 방지 방안 연구)

  • Yoo, Soonduck;Choi, Taein;Jo, Seongwon
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.21 no.5
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    • pp.103-111
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    • 2021
  • The purpose of this study is to study a method for preventing collisions of multiple drones in controlled airspace. As a result of the study, it was proved that it is appropriate as a method to control drone collisions after setting accurate information on the ROI (Region of Interest) area estimated based on the expected drone path and time in the control system as a method to avoid drone collision. As a result of the empirical analysis, the diameter of the flight path of the operating drone should be selected to reduce the risk of collision, and the change in the departure time and operating speed of the operating drone did not act as an influencing factor in the collision. In addition, it has been demonstrated that providing flight priority is one of the appropriate methods as a countermeasure to avoid collisions. For collision avoidance methods, not only drone sensor-based collision avoidance, but also collision avoidance can be doubled by monitoring and predicting collisions in the control system and performing real-time control. This study is meaningful in that it provided an idea for a method for preventing collisions of multiple drones in controlled airspace and conducted practical tests. This helps to solve the problem of collisions that occur when multiple drones of different types are operating based on the control system. This study will contribute to the development of related industries by preventing accidents caused by drone collisions and providing a safe drone operation environment.

Prediction of calcium and phosphorus requirements for pigs in different bodyweight ranges using a meta-analysis

  • Jeon, Se Min;Hosseindoust, Abdolreza;Ha, Sang Hun;Kim, Tae Gyun;Mun, Jun Young;Moturi, Joseph;Lee, SuHyup;Choi, Yo Han;Lee, Sang Deok;Sa, Soo Jin;Kim, Jin Soo
    • Journal of Animal Science and Technology
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    • v.63 no.4
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    • pp.827-840
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    • 2021
  • Several studies have focused on Ca and P requirements for pigs. These requirements are estimated from their retention and bone formation. However, modern pig breeds have different responses to dietary Ca and P than traditional breeds, and their requirements are expected to change on an annual basis. Besides individual Ca and P needs, the Ca to P ratio (Ca/P) is an important factor in determining requirements. This study aimed to implement a linear and quadratic regression analysis to estimate Ca and P requirements based on average daily gain (ADG), apparent total tract digestibility (ATTD) of Ca (ATTD-Ca), ATTD of P (ATTD-P), and crude protein (CP) digestibility. Results show that Ca/P had linear and quadratic effects on ADG in the phytase-supplemented (PS) group in both the 6-11 kg and 11-25 kg categories. In the latter category, the CP digestibility was linearly increased in response to increasing Ca/P in the without-phytase (WP) group. In the 25-50 kg category, there was a linear response of ADG and linear and quadratic responses of CP digestibility to Ca/P in the PS group, while a linear and quadratic increase in CP digestibility and a quadratic effect on ATTD-Ca were observed in the WP group. In the 50-75 kg category, Ca/P had significant quadratic effects on ADG in the PS and WP groups, along with significant linear and quadratic effects on ATTD-Ca. In addition, Ca/P had significant quadratic effects on ATTD-P and led to a significant linear and quadratic increase in the CP digestibility in the WP group. In the 75-100 kg category, analysis showed a significant decrease in ATTD-Ca and ATTD-P in the PS and WP groups; in the latter, ATTD-P and ATTD-Ca were linearly decreased by increasing Ca/P. In conclusion, our equations predicted a higher Ca/P in the 6-25 kg bodyweight categories and a lower Ca/P in the 50-100 kg category than that recommended in the literature.

Recent Research Trends of Cryopreservation Technology Based on Microalgae Chlorophyta (미세조류 동결보존 기술 개발의 최근 연구 동향)

  • Yim, Jun-Ho;Seo, Yong Bae;Kim, Seon Min;Jeon, Young Jae
    • Journal of Life Science
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    • v.31 no.10
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    • pp.960-968
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    • 2021
  • Since microalgae research started on late 18 century, they have been recognized as one of the most important bioresources used in bioindustry. Owing to the large efforts paid to industrial application of this microorganisms, their importance on food/feed and bioactive compounds has been further extending into the environmental research areas including alternative energy resources, mitigation of the carbon emission, and waste-water treatment. However, despite the importance on their industrial application, the fundamental research field related to the long-term preservation of microalgae culture has not received much attention. However, a less labor intensive and cost-efficient preservation technology enabling biologically active and stable microalgae-culture provides a key success factor in the biotechnological application. Therefore, this study investigated various cutting-edge microalgae cryopreservation technologies currently developed so far, mainly targeting Chlorophyta, which occupies the largest taxon in the classification system of microalgae. In addition, for the development of successful cryopreservation technique, the key factors such as temperature control effect and preservative effect during cryopreservation of microalgae culture were investigated. In addition, the problems with current preservation technology that is being used in Korean domestic biological resource banks and the international microalgal resource banks are described. According to our investigation, currently no standard method for long-term preservation of microalgae is available due to their various morphological and physiological characteristics. To overcome such issues, much more efforts on fundamental research area on the identification of specific biomarker used for microalgae taxonomical classification and further systemic approaches based on strain-specific cryopreservation methods needed.

Determinants of Hotel Customers' Use of the Contactless Service: Mixed-Method Approach (호텔 고객의 비대면 서비스 이용의도의 영향요인에 대한 연구)

  • Chung, Hee Chung;Koo, Chulmo;Chung, Namho
    • Knowledge Management Research
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    • v.22 no.3
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    • pp.235-252
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    • 2021
  • The development of information and communication technology and COVID-19 have caused an unusual change in the hotel industry, and the demand for the contactless services such as service robots from hotel customers has surged. Therefore, this study investigates the perception of hotel customers on contactless services by applying a mixed-method analysis. Specifically, this study identified the causal correlations between variables through the structural equation model, and further applied the fuzzy set qualitative comparison analysis to derive patterns of variables that form the intention to use the non-face-to-face services. As a result of the analysis, it was shown that service experience co-creation, palyfulness, personalization, and trust had a significant effect on intention to use through the contactless service use desire. On the other hand, in the results of fuzzy-set qualitative comparison analysis, playfulness was derived as a core factor in all patterns. Based on these analysis results, this study provides academic basis for in-depth understanding of hotel customers' perception of contactless service and specific guidelines for hotel managers on the contactless service strategies in the era of COVID-19 pandemic.

A Study on the Characteristics of Blockchain-Based Financial Platform and the Intention to Use (블록체인 기반 금융 플랫폼 특성과 사용 의도에 관한 연구)

  • Lee, Sangho;Cho, Kwangmoon
    • Journal of Internet of Things and Convergence
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    • v.7 no.3
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    • pp.81-90
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    • 2021
  • In this study, the effect of user characteristics and technical characteristics of a blockchain-based financial platform on the intention to use of financial consumers was analyzed. Also, in this influence relationship, we analyzed what kind of causal relationship between relative advantage and perceived risk on intention to use. From June 1 to July 30, 2021, a non-face-to-face self-filling online survey was conducted with a sample of subjects who had experience using a financial platform grafted with blockchain technology, and the study was conducted in 187 copies. For statistical processing, frequency analysis, exploratory factor analysis, reliability analysis, correlation analysis, multiple regression analysis and 3-step mediated regression analysis were performed using SPSS 21.0 program. The significance level of the statistical value was set to less than 95%. The research results are as follows. First, it was found that innovativeness and usefulness affect the intention to use in the user characteristics. Second, in the technical characteristics, compatibility and reliability were found to affect the intention to use. Third, it was found that relative advantage and perceived risk play a partial mediating role in the relationship between user characteristics and intention to use. Fourth, it was found that relative advantage and perceived risk play a partial mediating role in the relationship between technical characteristics and intention to use. Fifth, it was found that there were differences in the ubiquity of user characteristics, compatibility of technical characteristics and intention to use according to the experience of using the certificate. The results of this study can contribute to the development of a financial platform based on the Internet of Things.