• Journal of Technology Innovation
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• v.20 no.1
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• pp.235-262
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• 2012

Although a commercialization of developed technology is an important factor for firm's competitiveness, the success rate in technology commercialization is significantly low. This fact raises a need of an analysis on factors affecting success in technology commercialization. Thus, in this study, in order to determine the success factors of technology commercialization, statistical analysis is done on 4 different elements of Korean automobile industry firms: managerial group attitude, market orientation, technology quality, and government support; and developed a causal-relationship model of the above elements and commercialization. In the developed model, two moderating variables, corporate ability and industry classification, are added to determine the level of correlations respect to two moderating variables. As a result of hypothesis tests, market orientation, managerial attitude as an antecedent variable; and government support, technology quality as an antecedent variable, both have significant correlation with technology commercialization. For moderating variables, a corporate ability has moderating effects on the connections of managerial attitude, market orientation and technology commercialization; but an industry classification has a moderating effect only on the link between technology quality and government support. The results of this research serve a contribution to the development of R&D efficiency improvement by providing government with direction in science & technology policy.

• Radiation Oncology Journal
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• v.11 no.1
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• pp.43-50
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• 1993

We evaluated frequency and types of chromosomal aberrations by ionizing radiation in cancer patients treated with radiotherapy in our institution. Twenty-five patients with various types of carcinomas such as lung, uterine cervix, esophagus, rectum, head and neck and pancreatic cancers were studied immediately before and after external beam radiotherapy. The frequency of aberrant metaphase prior to treatment was $4.93{\%}$, which was higher than that of control group. Especially in lung cancer, the freuqency of aberrant metaphase was three times higher than control group. A comparison of chromosomal abnormalities observed before and after radiotherapy demonstrated that proportion of aberrant rnetaphases was significantly inreased to $22.13{\%}$. Major chromosomal aberrations like structural abnormalities showed remarkalbe increase from 65.45 to $88.45{\%}$ after the treatment. Also the numbers of chromosomal alterations per cell were increased by a factor of 6.5. Aberrations with two or more break points were more prominently increased, compared with aberrations with single break point. The number of chromosomal break points was noted to be higher than expected value in No.1, 3, 8 and 11 chromosomes and lower in No.13, 15, 17 and 21 chromosomes. Based on this study, we believe that the distribution of chromosomal breakage is related with gene and chromosomal rearrangement which could result in the development of cancers.

• Journal of Veterinary Clinics
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• v.27 no.3
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• pp.262-267
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• 2010

Magnesium ($Mg^{2+}$) is an essential co-factor for over 325 physiological and biochemical processes so that plays a central role of neuronal activity, cardiac excitability, neuromuscular transmission, muscular contraction, vasomotor tone, and blood pressure significantly related to physical performance. However, only limited information on blood ionized $Mg^{2+}$ ($iMg^{2+}$) regarding to physical exercise is available and the data from blood total $Mg^{2+}$ detection are inconsistent. This present study investigated the changes of blood $iMg^{2+}$ correlated with metabolic demands during acute high-intensive exhaustive physical exercise in rats. After exhausted swimming (3-4 hours), blood pH, glucose, $HCO_3{^-}$, oxygen and ionized $Ca^{2+}$ ($iCa^{2+}$) were significantly decreased, whereas lactate, carbon dioxide, $iMg^{2+}$, ionized $Na^+$ and ionized $K^+$ were significantly increased. During the exhausted swimming, the changes in $iMg^{2+}$ showed a significant negative correlation with changes in pH, glucose, $HCO_3^-$ and $iCa^{2+}$, however a significant negative correlation with changes in lactate and anionic gap. It is concluded that the acute high-intensive exhaustive physical exercise could produced hypermagnesemia, an increase in blood $iMg^{2+}$ via stimulation of $iMg^{2+}$ efflux following increase in intracellular $iMg^{2+}$ from muscle induced by metabolic and respiratory acidosis.

• 한국해양학회지
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• v.24 no.1
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• pp.52-61
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• 1989

The daily net primary production by phytoplankton and ammonium excretion by macrozooplankton (> $350{\mu}m$) were measured to understand the nitrogenous nutrient dynamics in the southern part of the East Sea of Korea. At most of the staions, water columns were well stratified and strongly developed pycnoclines and matching nutriclines could be found near the 20-60m. Total chlorophyll ranged between $1.22-3.24{\mu}g$ ChI/l and nano-fractions of chlorophyll ranged from 43.2 to 99.6% in the surface layer. The daily net primary production by phytoplankton ranged from 0.75 to 2.04 gC/$m^2$/d and averaged to be 1.5 gC/$m^2$/d. 1t is evidenced that the primary production and chlorophyll content are relatively high in frontal waters where the North Korean Cold Water meets with the East Korean Warm Water. The turnover time of nitrate in the euphotic zone ranged from 0.2 day to 1.6 day and averaged to be 0.8 day. The N:P ratio of the study area shows on the average 13.4 which indicates nitrogenous nutrient to be the limiting factor for phytoplankton growth. Ammonium excretion by macrowoplankton averaged out to 1.3mg at-N/$m^2$/d, and contributed 7.3% of daily total nitrogen requirement by phytoplankton in this area. Calculation of upward flux of nitrate to the surface mixed layer from the lower layer approximates 7% of nitrogen requirement by phytoplankton.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.20 no.1
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• pp.29-35
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• 2015

Dissolved nutrients in seawater are recognized as an essential biogeochemical factor for detecting global environmental changes. The importance of nutrient reference material for seawater has been increased greatly for the comparison of nutrient data, measured in different time and space in global ocean by various researchers with different levels in nutrient analysis skill. In this study, we described the homogeneity and stability of nutrient reference material for seawater using natural seawater, collected at a station of Shihwa Lake, at a coastal station near Uljin (surface water), and at a station over the Ulleung Basin (surface water and 1500 m depth water) and sterilized. Based on the homogeneity data, the nutrient reference materials has similar homogeneity compared to other nutrient reference materials. During 3-13 month period, there was no unidirectional trend of increase or decrease in nutrient concentration of newly developed nutrient reference material for seawater. However, a sustained measurement is required to check stability for longer period.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2013.04a
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• pp.835-841
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• 2013

Modern solid-state gyroscopes (HRG) with hemispherical resonators from high-purity quartz glass and special surface superfinishing and ultrathin gold coating become the best instruments for precise-grade inertial reference units (IRU) targeting long-term space missions. Designing of these sensors could be a notable contribution into development of Korea as a space nation. In participial, 40mm diameter thin-shell resonator from high-purity fused quartz, fabricated as a single-piece with its supporting stem has been designed, machined, etched, tuned, tested, and delivered by STM Co. (ATS of Ukraine) several years ago; an extremely-high Q-factor (upto 10~20 millions) has been shown. Understanding of the best way how to match such a unique sensor with inner glass assembly of the gyro means how to use the high potential in a maximal extent; and this has become the urgent task. Inner quartz glass assembly has a very thin indium (In) layer soldered the resonator and its silica base (case), but effects of internal resonances between operational modal pair of the shell-cup and its side (parasitic) modes can notable degrade the potential of the sensor as a whole, instead of so low level of resonator's intrinsic losses. Unfortunately, there are special combinations of dimensions of the parts (so-called, "resonant sizes"), when intensive losses of energy occurs. The authors proposed to use the length of stem's fixture as an additional design parameter to avoid such cases. So-called, a cyclic scheme of finite element method (FEM) and ANSYS software were employed to estimate different combinations of gyro assembly parameters. This variant has no mismatches of numerical origin due to FEM's discrete mesh. The optimum length and dangerous "resonant lengths" have been found. The special attention has been paid to analyses of 3D effects in a cup-stem transient zone, including determination of a difference between the positions of geometrical Pole of the resonant hemisphere and of its "dynamical Pole", i.e., its real zone of oscillation node. Boundary effects between the shell (cup) and 3D short "beams" (inner and outer stems) have been ranged. The results of the numerical experiments have been compared with the classic model of a quasi-hemispherical shell band with inextensional midsurface, and the solution using Rayleigh's functions of the $1^{st}$ and $2^{nd}$ kinds. To guarantee the truth of the recommended sizes to a designer of the real device, the analytical and FEM results have been compared with experimental data for a party of real resonators. The consistency of the results obtained by different means has been shown with errors less than 5%. The results notably differ from the data published earlier by different researchers.

• Journal of the Korean Wood Science and Technology
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• v.39 no.3
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• pp.269-280
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• 2011

Today, global warming is one of main problems all over the world. The cause of the global warming is carbon dioxide outbreak by the rapidly increasing energy use. Therefore, it is necessary to save energy in each industrious field. It was investigated that the half of total energy consumption over the world was used for construction and building. Therefore, the saving of the building energy plays a significant role in decreasing total energy consumption. With the considerable increase in building energy consumption, a green building rating system and certification are required to reduce building energy consumption and $CO_2$ emissions. Of various elements reducing building energy, the thermal conductivity of materials affects the energy consumption as a basic element, which is directly related with reducing energy consumption. In particular, as the thermal conductivity of finishing materials is an important factor to decide heating energy efficiency of floor heating system, the investigation and development are necessary.

• Korean Journal of Food Science and Technology
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• v.41 no.3
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• pp.258-264
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• 2009

The principal objective of this study was to estimate the measurement uncertainty associated with determination of deoxynivalenol (DON), a mycotoxin generated by Fusarium strain, in food. In service of this goal, wheat as a food matrix was analyzed via high performance liquid chromatography-ultraviolet (HPLC-UV) detection using an immunoaffinity column for clean-up. The uncertainty sources in the measurement process were identified by sample weight, final volume, and sample concentration in extraction volume with components including standard stock solution, working standard solution, 5 standard solutions, calibration curve, matrix, and instrument. The expanded uncertainty for DON at a concentration of 300 ${\mu}g/kg$ was estimated as 71.62 ${\mu}g/kg$ using a coverage factor of two, which provides a confidence level of approximately 95%. The most influential component in the uncertainty sources was the recovery of the wheat matrix, followed by the calibration curve. These results indicate that all efforts may be directed toward reducing the uncertainties of the recovery of the wheat matrix and the calibration curve to obtain a reliable HPLC-UV method for DON analysis in wheat.

• The Korean Journal of Health Service Management
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• v.1 no.1
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• pp.59-74
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• 2007

Considering the characteristics of the Korean family which maintain a close connection with their patients from the moment of their falling sick to hospitalization to discharge, the family is the most important environmental factor of the social supporting system, and is the important object of the client as well as activity system. The medical social work intends to meet the practical needs of aged chronic patients, providing them and their family with a professional human service. The end of this study is to find out the hardships of both the aged chronic patients and their family as well as their needs for the social welfare service, and to search out the way of comprehensive social work service. The summary of the analysis of the survey is as follows: 1. The needs of aged chronic patients are divided into those of the solution of the problems of falling ill, social welfare program and discharge. Those needs arc affected by the various factors of the types of hospitals, the patients' age, the kinds of insurance, and the supporting systems, etc. Accordingly, the assessment of the needs of the patients are asked to be done comprehensively in accordance with the kinds of diseases and social environments. 2. The importance of the family to the aged chronic patients is evident. The family plays a decisive role in the patients' hospitalization and discharge, the family being an important supporting system and making it necessary to take an approach to client system. The family has difficulty in getting connection of community resources, in adapting to social life after the patient's discharge, and in paying the treatment. The family suffers the secondary hardships more than the burden of the treatment expenses. 3. For this reason various interventions are needed to reduce the stress caused by supporting and nursing patients. Thus the social welfare service for the aged chronic patients and their family needs the following prepositions: 1. It is the characteristics of the aged chronic patients that they need continuous care and that the strengths of the patients and their family cannot be too much emphasized, and that comprehensive assessment based on the connection 'with the community and the mutual interchange 'with the environment, is much emphasized. 2. The family of the aged chronic patient is a resources system as well as a client one. 3. Another characteristic of the aged chronic patients is that with the resources connection in mind, it needs an active intervention of social workers in the community. With these prepositions considered, the development of practical social work service for the aged chronic patients is thought urgently needed.

• Journal of Life Science
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• v.22 no.8
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• pp.1107-1113
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• 2012

In this experiment, the effects of Pueraria thunbergiana extracts on the activation of immune cells were studied. An immune cell-activating factor was partially purified from P. thunbergiana by means of physiological saline extraction, acetone precipitation, and heating inactivation. P. thunbergiana extracts increased the proliferation of spleen cells and induced the production of IL-2, IL-6, TNF-${\alpha}$, and IFN-${\gamma}$ by spleen cells. Also, they increased the proliferation of purified B cells and the production of IgM antibody in a dose-dependent fashion. The extract self-induced NO synthesis in a mouse macrophage cell line (RAW264.7). When cell lines were treated with extracts, the cytokines' (IL-$1{\beta}$, IL-6, and TNF-${\alpha}$) production was markedly increased. Therefore, P. thunbergiana extract can self-activate spleen cells, B cells, and macrophages. These results might be useful in further studies into a possible immune-activating agent derived from P. thunbergiana for the development of functional foods and drugs.