• Korean Journal of Agricultural Science
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• v.23 no.1
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• pp.25-38
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• 1996

To investigate the stability problem of irrigation-drainage channel excavation slope on soft ground, analyzed the behavior of the soft ground with excavation slope by the limit equilibrium method and the finite element method, and compared with field tests. The results of this study were summarized as follows; 1. When rapid drawdown the water level, the crack was occurred by the effect of the excess pore water pressure, and the pore water pressure was decreased slowly. 2. As the width of excavation was larger, the crack width was larger. And, excavated depth was deeper, the progressive failure was appeared. 3. When the soft ground excavation was small-scale, the minimum safety factor was more effected by cohesion(1.0, 1.5, 2.0, 2.5, 3.0) than excavated slope inclination(1:l, 1:1.5, 1:2). 4. As excavation was progressed, the settlement occurred on the top-slope due to plastic domain, and heaving was occurred at the bottom of excavation. 5. The maximum shear stress was appeared greatly as the base part of slope went down. Because of the increase of the maximum shear stress, tension area occurred and local failure possibility was increased. 6. As the excavation depth was increased, the maximum shear strain was appeared greatly at the base of slope and distribution pattern was concentrated beneath the middle of slope.

• Management & Information Systems Review
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• v.23
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• pp.25-40
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• 2007

In the highly competitive and divers world of financial market, customer is the single most important factor to company's survival. Especially, creating a relationship with valued customers is a key to success. CRM provides the mean to retain high value customers. It takes a prospect of what customers expect. Utilizing those knowledge can help the products and service meet the customers' needs, thereby maximizing customer satisfaction and company's profit. In this report, I am going to suggest a few ways to develop successful CRM in the life insurance industry. First, CRM should innovate the way of communication to keep pace with Web 2.0 era. In other words, the customer's needs should be caught by real-time communication than traditional off-line market research. Thus, the functionality and specification of products can be decided by customer's direct choice so that the customers are able to purchase the understanding and experience of the products. Second, CRM project should consider whether the initial strategy plan can promise the stable growth of customer at the first step. When planning strategy, the project needs to identify what customer wants and how to fulfill the needs with stable growth of the customer. In addition, the CRM should be developed by realizing that customer centric benefits ultimately guarantee the growth of the organization. Third, CRM systems should enhance the organization's ability to take the customer's insight in a 360 degree view and to capture the voice of the customer directly. In order to develop the best matched product package, more precise customer segmentation should be ahead of market segmentation strategy. Forth, the biggest reward from CRM will be a customer royalty program. Many successful banks are already planning and practicing customer royalty strategy. A comprehensive analysis of customers and their behavior allow organization to identify high value potential customers' needs and determine a strategy required to meet those needs. Even life insurance companies such as Prudential Korea are developing products designed for royal customers. Fifth, understanding and managing the experience of customer called Customer Experience Management also can increase customer satisfaction. Measuring only customers' experience and adapting it to marketing strategy make products position in the gap between the customers' expectation and experience not required by market. A key component of CEM is its application across all organizational functions. At last, the direction of change and development of CRM can be defined from the conceptualization of information technology represented by Ubiquitous and Web 2.0. Instead of just managing customer information, companies should take the initiative in personalized system with customer oriented strategy. Furthermore, with the regular communication between CRM stakeholders (Sales-Marketing-IT), customer's demand should be directly reflected to enterprise strategy in real time.

• Journal of Sasang Constitutional Medicine
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• v.15 no.3
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• pp.88-99
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• 2003

Background and Objective : The status of development of instruments to assess the 'health status' reflecting the concept of Sasang Constitutional Medicine is still far from satisfaction, despite their importance in building basic data for health promotion, evaluation of effectiveness of treatment, health policy and so on. for these reasons the health scale of Sasang Constitutional Medicine shod be developed. Therefore as from of preliminary research, this study is to review the concept of health and symptoms in health status in Sasang Constitutional Medicine. Methods : It was researched as bibliologically with Dong-mu's chief medical writings such as ${\ulcorner}Dongyi$ Soose $Bowon{\lrcorner}$(東醫壽世保元)${\ulcorner}Dongyi$ Soose Bowon Sasang Chobongyun(東醫壽世保元四象草本卷)${\lrcorner}$ - Results and conclusion : 1. In Sasang Constitutional Medicine, it is suggested that Inherent vitality(命脈實數) has relations to health and Knowledge-Acting(知行) is a primary factor which affects health. And it is thought that Healthy condition(完實無病) is that human being has enough Healthy energy(保命之主) of Small viscera. 2. In Sasang Constitutional Medicine, it is thought that stool, urine, sweating and digestion become important indexes to measure the physical health state. 3. In Sasang Constitutional Medicine, it is thought that the mental health is in control of inclination of mind by golden mean(中庸) and in tranquillity of constant mind according to constitution. 4. In Sasang Constitutional Medicine, it is thought that the social health is state thar can do social acting harmoniously by keeping away from alcohol, sexual appetite, property and power.

• Korean Journal of Environment and Ecology
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• v.27 no.6
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• pp.757-764
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• 2013

This study was conducted to determine factors causing urban temperature rises in a mixed urban and rural city in Korea. The study site was Miryang City. For this study, temperature changes over a 36 year period from 1974 to 2010, as well as changes made in the urban environment of the city were examined. Changes in the urban environment included data pertaining to both urban development and changing land use, as well as the changing lifestyle patterns of the populace. The study showed that a rise in the average annual temperature and the average annual mean-maximum temperature were statistically significant and the greatest determining factor for the temperature rise was a corresponding decrease in arable land. The study also showed that the decrease in cultivated land was directly and significantly related to an expansion of regional urbanization. There is a direct relationship between the decrease in cultivated land and an increase in the annual-mean-maximum temperature compared with annual-mean temperature. This increase can be explained as arable land works as an "island" of cooler temperatures in the hottest times of the day. A decrease of $1km^2$ of arable land is expected to cause an increase of $0.08^{\circ}C$ of annual-maximum-mean temperature and $0.06^{\circ}C$ of annual-mean temperature.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.26 no.4
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• pp.217-224
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• 2014

Cochlodinium polykrikoides is a typical harmful algal species which generates the red-tide in the coastal zone, southern Korea. Accurate algal growth model can be established and then the prediction of the red-tide occurrence using this model is possible if the information on the optimal growth model parameters are available because it is directly related between the red-tide occurrence and the rapid algal bloom. However, the limitation factors on the algal growth, such as light intensity, water temperature, salinity, and nutrient concentrations, are so diverse and also the limitation function types are diverse. Thus, the study on the algal growth model development using the available laboratory data set on the growth rate change due to the limitation factors are relatively very poor in the perspective of the model. In this study, the growth model on the C. polykrikoides are developed and suggested as the optimal model which can be used as the element model in the red-tide or ecological models. The optimal parameter estimation and an error analysis are carried out using the available previous research results and data sets. This model can be used for the difference analysis between the lab. condition and in-situ state because it is an optimal model for the lab. condition. The parameter values and ranges also can be used for the model calibration and validation using the in-situ monitoring environmental and algal bloom data sets.

• Development and Reproduction
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• v.5 no.2
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• pp.181-187
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• 2001

Seasonal changes and circadian rhythm of plasma prolactin(PRL) concentration in mammals are mediated by melatonin. Pinealectomy or denervation of the pineal gland produces an increase in plasma PRL level. In the rat placenta several members of the PRL family gene are expressed during the late pregnancy. However, the full spectrum of their expression mechanisms and regulatory factors are not elucidated yet. Present study aimed to investigate the local expression of the melatonin receptor la(Me $l_{la}$ ) gene and the effect of melatonin on expression of prolactin-like protein A(PLP-A), a member of the PRL-family gene in the rat placenta. According to the RT-PCR, northern blot and in situ hybridization experiments, Me $l_{la}$ gene was locally expressed in the rat placenta, Me $l_{la}$ mRNA was localized mainly in the placental junctional and labyrinth zones. Interestingly, junctional zone of the placenta showed strong expression of Me $l_{la}$ at daytime(16:00) than at nighttime(22:00). Melatonin agonist, chlorornelatonin decreased the PLP-A mRNA levels in the rat placenta. These results suggest that melatonin coupled with Me $l_{la}$ , may act as a regulation factor that mediates the expression of the PLP-A gene in the rat placenta.

• Development and Reproduction
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• v.7 no.2
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• pp.95-103
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• 2003

Intracellular calcium is an important physiological factor in most cells, and ruthenium red and ryanodine play an important role as calcium modulators. Ruthenium red inhibits calcium-induced calcium release(CICR) from the intracellular calcium store. Ryanodine activates calcium release through ryanodine channel. The present experiment was performed to investigate the effects of two modulators on calcium ion metabolism and to determine their dose-dependency in oocyte and early embryo of mouse. Intracellular calcium ion concentration was measured in realtime by using confocal laser scanning microscope(CLSM) after loading of Fluo-3/AM in mouse oocytes and early embryos. Ruthenium red decreased intracellular calcium ion concentration in oocytes and early embryos at its high concentration(30, 300 $\mu$M). Ryanodine increased intracellular calcium ion concentration in oocytes and early embryos in low concentration(0.01 $\mu$M) but decreased that at higher concentrations(1, 10 $\mu$M). These results indicate that two modulators affected calcium ion metabolism in oocyte and early embryo of mouse, and their dose-dependency was different from somatic cell including myocytes.

• Development and Reproduction
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• v.10 no.2
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• pp.85-92
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• 2006

Progesterone(P4) is an important intermediate in the synthesis of androgens and estrogens. Furthermore, P4 itself plays a crucial role in ovulation, atresia and luteinization, and is essential for the continuation of early pregnancy in all mammalian species. In spite of the hormone's physiological importance, the exact action mechanism(s) of P4 in mammalian ovary has not been fully understood yet. In this context, a decades-long controversy regarding the identity of receptors that mediate non-genomic, transcription-independent cellular responses to P4 is presently attracting huge scientific interests. P4 may exert its action in mammalian ovary by several ways: 1) the well-documented genomic pathway, involving hormone binding to so-called classic cytosolic receptor(PGR) and subsequent modulation of gene expression by the ligand-receptor complex as transcription factor. 2) pathways are operating that do not act on the genome, therefore refered to as non-genomic actions. The prominent characteristics of the non-genomic P4 actions are: (i) rapid, (ii) insensitive to transcription inhibitors, (iii) transduced by membrane associated molecules. In particular, the non-genomic P4 actions could be mediated by: (a) classic genomic P4 receptor(PGR) that localizes at or near the plasma membrane, (b) a family of membrane progestin receptors(MPR $\alpha$, MPR $\beta$ and MPR $\gamma$), (c) progesterone receptor membrane component I(PGRMC1), and (d) a membrane complex composed of serpine I mRNA binding protein(SERBP1). The present review summarized these rapid signaling pathways of P4 in the mammalian ovary.

• Development and Reproduction
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• v.2 no.1
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• pp.21-27
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• 1998

The present study was performed to analyze the gene expressions of pituitary adenylate cyclase-activating polypeptide(PACAP) and its receptor in the rat uterus, a candidate for novel extrahypothalamic source and target. The PACAP cDNA fragments corresponding to the common exon region which is found in both the rat hypothalamus and testis were produced from all tissue samples including the rat uterus by reverse transcriptionpolymerase chain reaction (RT-PCR). No PCR product was amplified from the rat hypothalamic, pituitary, ovarian and uterine samples when the 5' primer corresponding to the testis-specific exon 1 region was used, while the predicted size of product was detected from the testis sample. RT-PCR using the uterine RNA and specific primers for the PACAP receptor yielded products with predicted sizes. Transcripts for the rat uterine PACAP receptor were identified as type I isoforms with hip-hop and hip- or hop-type inserts. After pregnant mare's serum gonadotropin (15 IU) treatment of immature rats (day 25), the level of PACAP mRNA was increased in 24 h and 48 h group, and was declined to the lowest in 72 h group. The present study shows the presence of transcripts for PACAP and its receptor isoform in the rat uterus. These finding ssuggest that the uterine PACAP ight act as a novel autocrine and/or paracrine factor via its specific receptors on the reglulation of rat uterine function and physiology during the reproductive cycle.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.364-364
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• 2017

Saemangeum reclaimed land is a part of Saemangeum Development Project. Most of the persistent problems of Saemangeum reclaimed land remain to be related to soil salinity. Soil salinity is a major abiotic factor related to microbial community structure and also fungi have been reported to be more sensitive to salinity stress than bacteria. The aim of this study was conducted to investigate the effect of soil salinity levels on the microbial communities in Saemangeum reclaimed land using 454 pyrosequencing analysis. Soil samples was collected from 12 sites of in Saemangeum reclaimed land. For pyrosequencing, 27F/518R (bacteria) and ITS3/ITS4 (fungi) primers were used containing the Roche 454 pyrosequencing adaptor-key-linker (underlined) and unique barcodes (X). Pyrosequencing was performed by Chun's Lab (Seoul, Korea) using the standard shotgun sequencing reagents and a 454 GS FLX Titanium sequencing System (Roche, Inc.). In the soil samples, Proteobacteria (bacteria) and Ascomycota (fungi) shows the highest relative abundance in all the soil sample sites. Proteobacteria, Bacteroidetes, Plantomycetes, Gemmatimonadetes and Parcubacteria were shown to have significantly higher abundance in high salinity level soils than low salinity level soils, while Acidobacteria and Nitrospirae has significantly higher relative abundance in low salinity level soils. The abundance of fungal, Ascomycota has the highest relative abundance in soil samples, followed by Basidiomycota, Chlorophyta, Zygomycota and Chytridiomycota. Basidiomycota, Zygomycota, Glomeromycota and Cerozoa were show significantly higher relative abundance in low salinity level soils. The principal coordinate analysis (PCoA) and correlation analysis shown to salinity-related soil parameters such as ECe, Na+, SAR and EPS were affected to bacterial and fungal community structure. Proteobacteria, Bacteroidetes, Plantomycetes exhibited significantly positive correlation with soil salinity, while Acidobacteria exhibited significantly negative correlation. In the case of fungal community, Basidiomycota and Zygomycota were seen show significantly negative correlation with salinity related soil parameters. These results suggest that provide understanding effect of soil salinity on microbial community structure and correlation of microbial community with soil parameters in Saemangeum reclaimed land.