• Molecules and Cells
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• v.27 no.4
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• pp.397-401
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• 2009

Olig2 transcription factor is widely expressed throughout the central nervous system; therefore, it is considered to have multiple functions in the developing, mature and injured brain. In this mini-review, we focus on Olig2 in the forebrain (telencephalon and diencephalon) and discuss the functional significance of Olig2 and the differentiation properties of Olig2-expressing progenitors in the development and injured states. Short- and long-term lineage analysis in the developing forebrain elucidated that not all late Olig2+ cells are direct cohorts of early cells and that Olig2 lineage cells differentiate into neurons or glial cells in a region- and stage-dependent manner. Olig2-deficient mice revealed large elimination of oligodendrocyte precursor cells and a decreased number of astrocyte progenitors in the dorsal cortex, whereas no reduction in the number of GABAergic neurons. In addition to Olig2 function in the developing cortex, Olig2 is also reported to be important for glial scar formation after injury. Thus, Olig2 can be essential for glial differentiation during development and after injury.

• Journal of Agricultural Extension & Community Development
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• v.26 no.1
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• pp.17-30
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• 2019

Tourism motivation and involvement are important variables influencing visitors satisfaction. The study aims to identify the factors influencing visitors' satisfaction. Particularly, the study examine the moderating effects on tourism involvement between tourism motivation and visitors' satisfaction. Data were collected from 430 usable questionnaires among visitors of Gigisi local festival. Results of a factor analysis yielded three dimensions of tourism motivation which are family and local food, recreation and escape, and social factor. Results show that social factors among three dimensions of sense of community have significance for visitors satisfaction. And tourism involvement has a negative interactional effects as a moderator between recreation and escape motivation and involvement. It means that even though higher recreation and escape motivation, less likely to have visitors satisfaction if visitors have higher involvement in local festival. It was suggested that tourism motivation and involvement should be considered in local festival management and policy.

• Development and Reproduction
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• v.26 no.2
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• pp.79-90
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• 2022

Krüppel-like factor 10 (KLF10) regulates various cellular functions, such as proliferation, differentiation and apoptosis, as well as the homeostasis of several types of tissue. In the present study, we attempted a loss-of-function analysis of zebrafish Klf11a and Klf11b, which constitute human KLF10 homologs. Embryos injected with klf11b-morpholino (MO) showed developmental retardation and cell death, whereas klf11a-MO-injected embryos showed normal development. In klf11b-MO-injected embryos, a dramatic increase in the amount of zebrafish p53 mRNA might be the cause of the increase in that of bax. The degree of apoptosis decreased in the klf11b-MO and p53-MO co-injected embryos. These findings imply that KLF10 is a negative regulator of p53-dependent transcription, suggesting that the KLF10/p53 complex may play an important role in apoptosis for maintenance of tissue homeostasis during embryonic development.

• International Journal of Computer Science & Network Security
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• v.23 no.12
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• pp.145-150
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• 2023

The main purpose of the study is to identify the key aspects of modern innovative research in the field of education. In the modern informatized world, education is becoming a decisive factor in social development and an important component in the development of the human personality, increasing respect for human rights and freedoms. Today it is quite obvious that without the necessary education a person will not be able to provide himself with proper living conditions and realize himself as a person. The high level of education of the population is an important factor that positively influences the creation of favorable conditions for the full realization of the rights and freedoms of man and citizen. Today, active and interactive teaching methods are widely used. The use of interactive teaching methods ensures complete immersion of students in the learning process and is the main source of learning. The radical difference between traditional and interactive learning is that the student not only replenishes and strengthens his knowledge, but also complements and constructs new ones. The methodology includes a number of theoretical methods. As a result of the study, current trends and prerequisites of modern innovative research in the field of education were investigated.

• Journal of Korean Academy of Nursing
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• v.35 no.1
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• pp.95-103
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• 2005

Purpose: The purpose of this study was to develop an instrument of task performance evaluation for clinical nurses, thus testing the validity and the reliability of the scale. Method: Data was collected from 84 Head Nurses and 255 General Nurses. A conceptual framework, composed of 4 factors of meaning in task performance evaluation, was identified through review of the relevant literature. A total of 78 items were developed and were used on a five-point likert scale. Through factor analysis, items whose factor loading was below 0.50 were deleted, thus 35 items remained. To test the validity and reliability of the instrument, the SPSS 11.0 windows program was used. Result: The results of the factor analysis indicated that 4 factors were classified and the cumulative percent of variance was 67.54%. The results of the reliability test indicated that Cronbach's coefficient of the total 35 items was over 0.9176. The results of the factor analysis indicated that factor loadings of all items was over 0.50. Conclusively, the validity and the reliability of the scale were proven. Conclusion: This study was identified as a tool with a high degree of reliability and validity.

• Journal of Navigation and Port Research
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• v.39 no.5
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• pp.423-429
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• 2015

The expansion on the scale of international trade and rapid economic growth in Northeast Asia have caused intense competition among global companies for securing international logistics center in Northeast Asia. Analyzing location competitiveness for international logistics center in Northeast Asia, this paper aims to extract implications for enhancing locational competitiveness. Employing the relative importance among location selection factors extracted from AHP analysis in prior study, we evaluated the major five port-cities in Northeast Asia including Busan, Gwangyang, Shanghai, Qingdao and Tokyo. In the evaluations, Shanghai (3.926) ranked as the first, followed by Busan (3.859), Qingdao (3.555), Tokyo (3.013) and Gwangyang (2.915). Furthermore, the causal relationships between determinants for location choice decision (logistics factor, cost factor, market factor, service factor and environmental factor) and dependent variables (competitiveness of international logistics center, potentiality to growth, present intention to move into and future plan to move into) were analyzed to provide implications. Results provide useful insights for further improvements, and helps strategic agenda for future development of port-cities.

• Proceedings of the KSME Conference
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• 2001.06d
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• pp.840-845
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• 2001

Development of a small gas-turbine combustor for 100kW class APU(Auxiliary Power Unit) has been performed. This combustor is a reverse-annular type and has a tangential swirler in the liner head to improve the fuel/air mixing and flame stability. Three main and three pilot fuel injectors of the simplex pressure-swirl type are used. The performance target at the design condition includes a turbine inlet temperature of 1170K, a combustion efficiency of 99%, a pattern factor of 30%, and an engine durability of 3000 hours. Under developing the combustor, we conducted performance test of our first prototype(TS1) with some variants. As a result of the test, the performance targets of the combustor are satisfied except that the pattern factor is about 4% higher than target value. So, we redesigned the second prototype(TS2) and conduct performance test with the critical focus on pattern factor and exit mean temperature. We adopted TS2 four variant to check the improvement of pattern factor. As the result, the pattern factors of several variants were satisfied with the performance target. Finally, We chose the TS2A variant as a final combustor for our APU model.

• Journal of Korean Academy of Nursing
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• v.31 no.3
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• pp.369-379
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• 2001

Purpose: The purpose of this study was to develop the Nurse Presence Scale and to test the reliability and validity of the instrument. Method: The subjects verifying the scale's reliability and validity were adult patients being treated in three artificial kidney unit in Pusan and Taegu from August 1 to October 15, 2000. The data was analyzed by the SPSS/WIN 8.0 program. Result: A factor analysis and was conducted items that had a factor loading more than .40, and an eigen value more than 1.0 were seleclted. The factor analysis classified a total of seven factors statistically, but the seventh factor was excluded because community was less than 4%. Therefore, there were six factors, and its communality was 62%. The explanation of domain and factors based on the conceptual framework and item content are as follows: The first factor was 'interaction' in emotional areas, the second domain was 'empathy' in cognitive areas, the third was 'attention' in emotional areas, the fourth was 'openness' in emotional areas, the fifth was 'sensitivity' in behavioral areas, and the sixth was 'physical assist' in behavioral areas. Cronbach's α coefficient to test reliability of the scale was .9766 for a total 49 items. Conclusion: The Scale for Nurse Presence developed in the study was identified as a tool with a high degree of reliability and validity. Therefore, this scale can be effectively utilized for the evaluation of nurse presence in clinical settings.

• Korean journal of food and cookery science
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• v.22 no.1 s.91
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• pp.96-104
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• 2006

This study evaluated the menus of native foods menu in the Jeonju city area in order to present possible improvements. The study examined twenty native food restaurants that target the visitors to the Jeonju city area from July 20 to August 12, 2005. These restaurants specialize in Jeonjubibimbap, Kongnamulgukbap, Hanjeongsik, and Dolsotbibimbap, which are all native foods of Jeonju. Restaurant patrons were randomly selected on leaving the study aim was explained, and questionnaires were distributed. of 200 papers, only 109 were suitable for statistical analysis. First, four factors of menu evaluation were drawn out: inner shape factor of food, outer shape factor of food, sanitation factor, and service factor. Second, the analysis showed statistically significant difference at the 5% significance level in age, job, and monthly income. Third, regression analysis between the factors on menu evaluation and the variables on their intention to visit the restaurant again, indicated that the inner shape factor of food influenced the intention to visit again. It is expected that these study results will assist the employees, restaurant managers, and chefs in making the best practical use of the basic ingredients to promote food quality and increase sales, which will lead to the further development of Jeonju city.

• Research in Community and Public Health Nursing
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• v.19 no.2
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• pp.247-259
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• 2008

Purpose: This study was conducted to develop a teacher-efficacy scale which is adequate for heath education teachers. Method: A preliminary questionnaire was made based on the hypothetical factors. A total of 364 health education teachers answered to the preliminary test, and the potential factors of teacher-efficacy were checked out by exploratory factor analysis (EFA). In the main test 378 health education teachers answered, the factor structure was drawn by EFA, and confirmatory factor analysis (CFA) was conducted to test and the fitness of the factor model. Results: Through the preliminary test, 5 potential factors were found, which were instruction, health-service, administrative task, interpersonal relationship, and community connection. Also, 48 items were reduced to 31 items. Through the main test, from the 34 items were extracted 4 factors with 24 items, And then teacher-efficacy scale was developed, which included the subscales of instruction efficacy, health-service efficacy, task-interpersonal efficacy, and community connection efficacy. Conclusion: Different from that for other subject teachers, the factor structure for health teachers had 4 factors with 24 items. The scale developed in this study is consistent with health teachers' work areas, and for this reason, has significance as a adequate and valid scale to measure teacher-efficacy of health education teachers.