• Title/Summary/Keyword: Developing Sequence

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Developing Stock Pattern Searching System using Sequence Alignment Algorithm (서열 정렬 알고리즘을 이용한 주가 패턴 탐색 시스템 개발)

  • Kim, Hyong-Jun;Cho, Hwan-Gue
    • Journal of KIISE:Computer Systems and Theory
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    • v.37 no.6
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    • pp.354-367
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    • 2010
  • There are many methods for analyzing patterns in time series data. Although stock data represents a time series, there are few studies on stock pattern analysis and prediction. Since people believe that stock price changes randomly we cannot predict stock prices using a scientific method. In this paper, we measured the degree of the randomness of stock prices using Kolmogorov complexity, and we showed that there is a strong correlation between the degree and the accuracy of stock price prediction using our semi-global alignment method. We transformed the stock price data to quantized string sequences. Then we measured randomness of stock prices using Kolmogorov complexity of the string sequences. We use KOSPI 690 stock data during 28 years for our experiments and to evaluate our methodology. When a high Kolmogorov complexity, the stock price cannot be predicted, when a low complexity, the stock price can be predicted, but the prediction ratio of stock price changes of interest to investors, is 12% prediction ratio for short-term predictions and a 54% prediction ratio for long-term predictions.

Biogeographic pattern of four endemic Pyropia from the east coast of Korea, including a new species, Pyropia retorta (Bangiaceae, Rhodophyta)

  • Kim, Sun-Mi;Choi, Han-Gu;Hwang, Mi-Sook;Kim, Hyung-Seop
    • ALGAE
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    • v.33 no.1
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    • pp.55-68
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    • 2018
  • Foliose species of the Bangiaceae (Porphyra s. l.) are very important in Korean fisheries, and their taxonomy and ecophysiology have received much attention because of the potential for developing or improving aquaculture techniques. Although 20 species of foliose Bangiales have been listed from the Korean coast, some of them remain uncertain and need further comparative morphological studies with molecular comparison. In this study, we confirm the distribution of four Pyropia species from the east coast of Korea, Pyropia kinositae, P. moriensis, P. onoi, and P. retorta sp. nov., based on morphology and rbcL sequence data. Although P. onoi was listed in North Korea in old floral works, its occurrence on the east coast of South Korea is first revealed in this study based on molecular data. P. kinositae and P. moriensis, which were originally described from Hokkaido, Japan, are first reported on the east coast of Korea in this study. Pyropia retorta sp. nov. and P. yezonesis share a similar thallus color and narrow spermatangial patches in the upper portion of the frond, and they have a sympatric distribution. However, P. retorta can be distinguished by the curled or twisted thalli and by molecular data. The biogeographic pattern of the two native species, P. kinositae and P. retorta, suggests that the east coast of Korea may have been a place of refugia during the Last Glacial Maximum (LGM), and then recolonized to the northern part of Japan through the restored East Korean Warm Current after the LGM.

DNA Repair Gene ERCC1 and XPD Polymorphisms Predict Glioma Susceptibility and Prognosis

  • Chen, Da-Qing;Yao, Dong-Xiao;Zhao, Hong-Yang;Yang, Shu-Juan
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.6
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    • pp.2791-2794
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    • 2012
  • Aims: We conducted a case-control study in a Chinese population to clarify the association between polymorphisms in ERCC1 and XPD and susceptibility and survival of glioma. Methods: A total of 393 cases and 410 controls were selected from March 2007 to December 2011. Genotyping of ERCC1 and XPD was conducted by TaqMan assays using the ABI Prism 7911HT Sequence Detection System. All analyses were performed using the STATA statistical package. Results: Polymorphisms in ERCC1 118C/T, ERCC1 8092C/A and XPD Asp312Asn showed no statistically significant difference between glioma cases and controls. However, individuals with the XPD 751Gln/Gln genotype had an increased risk of developing glioma compared with those with the Lys/Lys genotype (adjusted OR=1.64, 95% CI: 1.06-2.89). The ERCC1 118T/T genotype was associated with significantly higher median survival than the ERCC1 C/C genotype (HR=0.67, 95%CI=0.35-0.96). In addition, individuals with XPD 751Gln/Gln had a lower median survival time than XPD Lys/Lys carriers (HR=0.54, 95%CI=0.37-0.93). Conclusion: In conclusion, we observed that the XPD 751Gln/Gln genotype is associated with glioma susceptibility, and ERCC1 118 T/T and XPD 751Gln/Gln genotypes confer a significantly better prognosis.

The Stability, and Efficacy Against Penicillin-Resistant Enterococcus faecium, of the Plectasin Peptide Efficiently Produced by Escherichia coli

  • Chen, Xin;Wen, Yaoan;Li, Ling;Shi, Jiawei;Zhu, Zhe;Luo, Yuwen;Li, Yun;Chen, Rui
    • Journal of Microbiology and Biotechnology
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    • v.25 no.7
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    • pp.1007-1014
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    • 2015
  • Plectasin, the first defensin extracted from a fungus (the saprophytic ascomycete Pseudoplectania nigrella), is attractive as a prospective antimicrobial agent. The purpose of this study was to establish a bacterium-based production system and evaluate the antimicrobial activity of the resulting plectasin. A gene encoding plectasin, with the codon preference of Escherichia coli, was optimized based on its amino acid sequence, synthesized using genesplicing with overlap extension PCR, and inserted into the expression vector pGEX-4T-1. The fusion protein was expressed in the soluble fraction of E. coli and purified using glutathione Stransferase affinity chromatography. Plectasin was cleaved from the fusion protein with thrombin and purified by ultrafiltration. The purified plectasin showed strong, concentrationdependent antimicrobial activity against gram-positive bacteria, including antibiotic-resistant bacteria, especially penicillin-resistant Enterococcus faecium. This antimicrobial activity was equal to chemically synthesized plectasin and was maintained over a wide range of pH and temperatures. This soluble recombinant expression system in E. coli is effective for producing plectasin at a relatively lower cost, and higher purity and efficiency than prior systems, and might provide a foundation for developing a large-scale production system. Overall, plectasin shows potential as a novel, high-performance, and safe antibiotic for the treatment of refractory diseases caused by drug-resistant bacterial strains.

Analysis on the Flexural Behavior of Existing Reinforced Concrete Frame Structures Infilled with L-Type Precast Wall Panel (L형 프리캐스트 콘크리트 벽패널로 채운 기존 철근 콘크리트 골조 구조물의 휨 거동 분석)

  • Yu, Sung-Yong;Ju, Ho-Seong;Son, Guk-Won
    • Journal of the Korean Society for Advanced Composite Structures
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    • v.6 no.2
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    • pp.52-62
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    • 2015
  • This study aims at developing a new seismic resistant method by using precast concrete wall panels for existing low-rise, reinforced concrete beam-column buildings such as school buildings. Three quasi-static hysteresis loading tests were performed on one unreinforced beam-column specimen and two reinforced specimens with U-type precast wall panels. Top shear connection of the PC panel was required to show the composite strength of RC column and PC wall panel. However, the strength of the connection did not influence directly on the ultimate loading capacities of the specimens in the positive loading because the loaded RC column push the side of PC wall panel and it moved horizontally before the shear connector receive the concentrated shear force in the positive loading process. Under the positive loading sequence(push loading), the reinforced concrete column and PC panel showed flexural strength which is larger than 97% of the composite section because of the rigid binding at the top of precast panel. Similar load-deformation relationship and ultimated horizontal load capacities were shown in the test of PR1-LA and PR1-LP specimens because they have same section dimension and detail at the flexural critical section. An average of 4.7 times increase in the positive maximum loading(average 967kN) and 2.7 times increase in the negative maximum loading(average 592.5kN) had resulted from the test of seismic resistant specimens with anchored and welded steel plate connections than that of unreinforced beam-column specimen. The maximum drift ratios were also shown between 1.0% and 1.4%.

Analysis of the Bacterial Community in Ojingeo-jeotgal and Selection of Bacillus Species Inhibiting the Growth of Food Pathogens (오징어젓갈 Bacteria 군집분석 및 식중독균 생육저해 Bacillus 균주 선발)

  • Kim, Hye-Rim;Han, Seulhwa;Lee, Bitnara;Jeong, Do-Won;Lee, Jong-Hoon
    • Microbiology and Biotechnology Letters
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    • v.41 no.4
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    • pp.462-468
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    • 2013
  • Jeotgal is a generic term given to the high-salt-fermented seafood of Korea. This study aimed at developing an overview of the bacterial community present in Ojingeo-jeotgal, a highly consumed type of jeotgal, which is made with squid. Bacteria were isolated and purified from two samples on six different kinds of media and identified by 16S rRNA gene sequence analysis. Among the 121 total isolates, the most dominant genus was Bacillus, followed by coagulase-negative staphylococci (CNS) and lactic acid bacteria (LAB). CNS were detected in both samples, but LAB were observed in only a single sample. Six strains of Bacillus species inhibiting the growth of food pathogens, Staphylococcus aureus and Vibrio parahaemolyticus, were selected from the 121 isolates. These were found to inhibit the growth of both pathogens in addition to displaying proteolytic activities on media containing 6% NaCl and 2% skim milk.

Improvement of Rapid Sand Filtration to Two Stage Dual Media Filtration System in Water Treatment Plant (정수처리장내 급속모래 여과지의 이단복합여과시스템으로의 개량)

  • Woo, Dal-Sik;Hwang, Kyu-Won;Kim, Joon-Eon;Hwang, Byung-Gi;Jo, Kwan-Hyung
    • Journal of Environmental Health Sciences
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    • v.37 no.2
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    • pp.141-149
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    • 2011
  • This study aimed for developing a two stage dual media filtration system. It has a sand and activated carbon layer above the under-drain system, and a sand layer above the middle-drain system for pretreatment. When retrofitting an old sand filter bed or designing a new one, this technology can substitute the existing sand filter bed without requiring a new plant site. The removal rate of total particle is 93, and 3~7 ${\mu}m$ and 5~15 ${\mu}m$ particles are all 97%. These high removal efficiencies of each pollutant due to adsorption and biological oxidation in activated carbon filter layer. The best backwashing method of two stage dual media filtration system is ascertained by air injection, air + water injection and water injection sequence. In this study, a pilot plant of two stage and dual filtration system was operated for 4 months in water treatment plant. The stability of turbidity was maintained below 1 NTU. The TOC, THMFP and HAAFP were removed about 90% by two stage and dual media filtration system, which is almost 2 times higher than existing water treatment plant.

An Empirical Study on Critical Success Factors in Implementing the Web-Based Distance Learning System : In Case of Public Organization. (사이버교육 효과의 영향요인에 관한 실증적 연구: 공공조직을 중심으로)

  • 정해용;김상훈
    • The Journal of Information Systems
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    • v.11 no.1
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    • pp.51-74
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    • 2002
  • The purpose of this study is to empirically investigate critical success factors for effective implementation of web-based distance learning system. First of all, four critical success factors are theoretically derived from reviewing previous research. They are: (1) learner-related factor including the variables such as teaming ability, learning attitude, and attending motivation, (2) environmental factor including the variables of physical and mental support for learners, (3) instructional design factor represented by one variable, the degree of appropriateness of learning contents, and (4) the factor concerning the level of self-directed learning readiness embracing the variables such as curiosity for learning, openness towards challenge of learning and affection for learning. Subsequently, the relationships between these four critical success factors and the degree of learning satisfaction are empirically investigated. The data for empirical analysis of the research are collected from 1,020 respondents who have already passed the web-based distance learning courses which have been implemented in Information and Communication Officials Training Institute. Out of 1,020 responded questionnaires, 875 data were available for statistical analyses. The main results of this study are as follows. Firstly, the most important factor for successful implementation of the web-based distance learning system is shown to be the instructional design factor, and in the next place, the self-directed learning readiness factor, the environmental factor and the learner-related one in sequence. Secondly, additional analysis of the variables included in the instructional design factor shows that availability of practical information and knowledge is the most influencing variable, and next, interesting composition of contents, reasonable learning amount, optimal level of instruction, and understandable explanation are significantly important in the descending order. Lastly, among learning motivators, strong intention of acquiring business knowledges and skills is found to be the most important satisfier in the web-based distance learning. The theoretical contribution of this study is to derive a comprehensive model of critical success factors for implementing the web-based distance learning system. And, the practical implication of this study is to propose efficient and effective guidelines for developing and operating the web-based distance learning system in the various kinds of organizations.

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KSR-III 비행시험 발사 시나리오 개발

  • Shin, Myoung-Ho;Seo, Jin-Ho;Kim, Kwang-Soo;Hong, Il-Hi
    • Aerospace Engineering and Technology
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    • v.2 no.1
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    • pp.140-152
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    • 2003
  • Scenario is a guiding principle of launch operation and control for rocket and ground support system. Therefore, developing a scenario is the first step to prepare for rocket launch, which is a critical task for success of KSR-III flight test. The launch scenario for KSR-III flight test is a procedural sequence of command and control signals to be given to rocket and ground support systems. In this paper, the UML object modeling method is applied to development of a launch scenario. First, the subsystems of the launch system are modeled by objects, and then the interfaces between each two subsystems are modeled by association links. The finally obtained object diagram of KSR-III launch system is used to analyzing flow of data and commands and control signals, and interactions. The scenario includes the sequences of pre-launch/launch operations and emergency operations.

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Mitochondrial D-Loop Variations for Discrimination of Commercial Korean Native Chicken Populations

  • Sultana, Hasina;Hoque, Md. Rashedul;Seo, Dong-Won;Kang, Bo-Seok;Heo, Kang-Nyeong;Jo, Cheorun;Lee, Jun-Heon
    • Korean Journal of Poultry Science
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    • v.39 no.4
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    • pp.311-315
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    • 2012
  • The increasing demand for Korean native chicken meat indicates that the discovery of haplotypes is very important from both economic and conservation points of view. In this study, mtDNA D-loop sequences from two crossbred Korean native chicken populations of 138 individuals were investigated. Twenty six nucleotide substitutions were identified from sequence analysis and were classified into 12 haplotypes. The haplotype H_8 represents 73.47% of Woorimatdag (chicken population) sequences, which were identified in all five Woorimatdag chicken populations investigated. The H_7 haplotype (Dhap1) for D population covers 45% sequences, which indicate maternal inheritance from black Korean native chicken. On the other hand, Chap3 and Chap4 for C population are specific haplotypes, as H_5 and H_2, respectively. Based on the network profiles, six SNPs (C199T, A239G, G242A, A291G, T330C and C391A) of the D-loop region are effective markers for discrimination between Woorimatdag and Hanhyup chicken populations. Also, the phylogenetic analyses of Woorimatdag and Hanhyup chicken populations were used to identify the genetic relationships among the haplotypes. The results presented here can be used for developing molecular markers to discriminate between two commercial Korean native chickens.