• Title/Summary/Keyword: Developing Measurement

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Precise ultrasonic coating and controlled release of sirolimus with biodegradable polymers for drug-eluting stent

  • Joung, Yoon Ki;Jang, Bu Nam;Kang, Jong Hee;Han, Dong Keun
    • Biomaterials and Biomechanics in Bioengineering
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    • v.1 no.1
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    • pp.13-25
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    • 2014
  • In the current study, a drug-eluting stent coated with biodegradable polymers and sirolimus was developed by using an ultrasonic nanocoater and characterized in aspects of surface smoothness and coating thickness. In addition, in vitro release profiles of sirolimus by changing top coating layer with different biodegradable polymers were investigated. Smooth surfaces with variable thickness could be fabricated by optimizing polymer concentration, flow rate, nozzle-tip distance, gas pressure, various solvents and ultrasonic power. Smooth surface could be generated by using volatile solvents (acetone, chloroform, and methylene chloride) or post-treating with solvent vapor. Coating thickness could be controlled by varying injection volume or polymer concentration, and higher concentration could reduce the coating time while obtaining the same thickness. The thickness measurement was the most effectively performed by a conventional cutting method among three different methods that were investigated in this study. Release profiles of sirolimus were effectively controlled by changing polymers for top layer. PLGA made the release rate 3 times faster than PDLLA and PLLA and all top layers prevented burst release at the initial phase of profiles. Our results will provide useful and informative knowledge for developing drug-eluting stents, especially coated with biodegradable polymers.

Reduced Order Identification and Stability Analysis of DC-DC Converters

  • Ali, Husan;Zheng, Xiancheng;Wu, Xiaohua;Zaman, Haider;Khan, Shahbaz
    • Journal of Power Electronics
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    • v.17 no.2
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    • pp.453-463
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    • 2017
  • This paper discusses the measurement of frequency response functions for various dc-dc converters. The frequency domain identification procedure is applied to the measured frequency responses. The identified transfer functions are primarily used in developing behavioral models for dc-dc converters. Distributed power systems are based upon such converters in cascade, parallel and several other configurations. The system level analysis of a complete system becomes complex when the identified transfer functions are of high order. Therefore, a certain technique needs to be applied for order reduction of the identified transfer functions. During the process of order reduction, it has to be ensured that the system retains the dynamics of the full order system. The technique used here is based on the Hankel singular values of a system. A systematic procedure is given to retain the maximum energy states for the reduced order model. A dynamic analysis is performed for behavioral models based on full and reduced order frequency responses. The close agreement of results validates the effectiveness of the model order reduction. Stability is the key design objective for any system designer. Therefore, the measured frequency responses at the interface of the source and load are also used to predict stability of the system.

An Overview of the ICF's Use in Korea

  • Lee, Haejung;Song, Jumin
    • The Journal of Korean Physical Therapy
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    • v.27 no.5
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    • pp.356-363
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    • 2015
  • Purpose: The purpose of this study was to investigate the overview of the use of the ICF in Korea. Methods: An integrative literature review from its publication in 2001 to May, 2015 was conducted; studies published from 2001 to May, 2015 were searched using RISS, KISS, DBpia, KoreaMed, PubMed, and ISI databases. For inclusion in the review, a study had to be published as a scientific article, must have participation of Korean researchers and developed in Korea, and should provide use of ICF. Results: A total of 108 publications were identified, and 89 studies met the inclusion criteria. Most eligible studies were related to clinical fields (n=41) and areas with the disabled (n=32). Interestingly, several studies showed how to use and/or adapt ICF in clinical practice e.g. reviews and case studies, whereas in the area of the disabled, descriptive studies reported ICF concepts comparing with the current disability policies and laws in Korea. The usage of ICF was found to be at various levels: introducing the ICF concept and model, collecting data using the ICF checklist, coresets, as well as ICF codes itself and presenting results in the ICF framework, developing measurement tools based on ICF concepts. Conclusion: Since introduction of the ICF in 2001, the use of the ICF in Korea has increased in different professionals as well as in levels of its applications.

Space Radiation Measurement on the Polar Route onboard the Korean Commercial Flights

  • Hwang, Jung-A;Lee, Jae-Jin;Cho, Kyung-Suk;Choi, Ho-Sung;Rho, Su-Ryun;Cho, Il-Hyun
    • Journal of Astronomy and Space Sciences
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    • v.27 no.1
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    • pp.43-54
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    • 2010
  • This study was performed by the policy research project of Ministry of Land, Transport and Maritime Affairs, which title is "Developing safety standards and management of space radiation on the polar route". In this research, total six experiments were performed using Korean commercial flights (B747). Three of those are on the polar route and the other three are on the north pacific route. Space radiation exposure measured on the polar route is the average 84.7 uSv. The simulation result using CARI-6M program gives 84.9 uSv, which is very similar to measured value. For the departure flight using the north pacific route, the measured space radiation is the average 74.4 uSv. It seems that is not so different to use the polar route or not for the return flight because the higher latitude effect causing the increase of space radiation is compensated by the shortened flight time effect causing decreasing space radiation exposure.

Fundamental Study on Developing the Technology for the Removal of Fluorescent Whitening Agents from the Process Water (공정수에 존재하는 형광증백제의 제거 기술에 대한 기초연구)

  • Lee, Ji-Young;Youn, Hye-Jung;Lee, Hak-Lae
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.41 no.1
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    • pp.24-29
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    • 2009
  • The use of fluorescent whitening agents (FWAs) increases as the demand for the whiter and brighter printing papers increases. FWAs are used as internal and surface treatment chemicals. FWAs that are not used properly in the papermaking process, however, remain in the process water and may demage the paper quality and processes. In this study, a new idea to eliminate FWAs from the process water, consisted of the floc formation of FWAs with cationic chemicals, such as cationic polyelectrolytes and alum, and the removal of the floc by screening or sedimentation, was proposed. Flocculation of FWAs, that is the first step to remove FWAs from the process water, was investigated using turbidity and particle size measurement. Relationship between turbidity and particle size showed that the turbidity could reflect the particle size change of FWA flocs and was proper for the evaluation of flocculation phenomena. Poly-DADMAC was more efficient than PEI to induce the flocculation of FWAs. Alum was effective chemical for the flocculation and sedimentation of FWAs.

The Design and fabrication of Capacitive Humidity Sensor Having Interdigital Electrodes and Its Signal Processing Circuit (빗살전극형 정전용량형 습도센서와 그 신호처리회로의 설계 제작)

  • Kang, Jeong-Ho;Lee, Jae-Yong;Kim, Woo-Hyun
    • The Transactions of the Korean Institute of Electrical Engineers P
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    • v.55 no.1
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    • pp.26-30
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    • 2006
  • For the purpose of developing capacitive humidity sensor having interdigital electrodes, interdigital electrode was modeled and simulated to obtain capacitance and sensitivity as a function of geometric parameters like the structural gap and thickness. For the development of ASIC, switched capacitor signal processing circuits for capacitive humidity sensor were designed and simulated by Cadence using $0.25{\mu}m$ CMOS process parameters. The signal processing circuits are composed of amplifier for voltage gain control, and clock generator for sensor driving and switch control. The characteristics of the fabricated sensors are; 1) sensitivity is 9fF/%R.H., 2) temperature coefficient of offset(TCO) is $0.4%R.H./^{\circ}C$, 3) nonlinearity is 1.2%FS, 4) hysteresis is 1.5%FS in humidity range of $3%R.H.{\sim}98%R.H.$. The response time is 50 seconds in adsorption and 70 seconds in desorption. Fabricated process used in this capacitive humidity sensor having interdigital electrode are just as similar as conventional IC process technology. Therefore this can be easily mass produced with low cost, simple circuit and utilized in many applications for both industrial and environmental measurement and control system, such as monitoring system of environment, automobile, displayer, IC process room, and laboratory etc.

An Experimental Study on the Break-up Characteristics of Twin-Fluid Nozze According to tile Variations of Feeding Mass-ratio (공급 질량비 변화에 따른 2유체 노즐의 액주분열특성에 관한 실험적 연구)

  • Kang, S.J.;Oh, J.H.;Rho, B.J.
    • Journal of ILASS-Korea
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    • v.1 no.1
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    • pp.63-75
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    • 1996
  • The purpose of this study is to investigate the break-up characteristics by taking advantage of a two-phase coaxial nozzle. Air and water are utilized as working fluids and the mass ratio air/water has been controlled to characterize the atomization, diffusion and development of mixing process. By way of a photographic technique, conventional developing structures and diffusion angles have been analyzed systematically with variations of mass ratios. The turbulent flow components of the atomized particles were measured by a two channel LDV system and the data were treated by an on-lined measurement equipment. According to the photographic results the spreading angles decreased because the axial inertia moment was relatively higher than the lateral one with respect to the increase of mass ratio. It is found the jet flow diffuses linearly in a certain limit region while the atomizing characteristics, in terms of the distributions of particle diameters did not show particular differences. It may be expected that these fundamental results can be used as reference data in studying the atomization, breakup and diffusions.

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Estimation of Interfacial Adhesion through the Micromechanical Analysis of Failure Mechanisms in DLC Film

  • Jeong, Jeung-Hyun;Park, Hae-Seok;Ahn, Jeong-Hoon;Dongil Kwon
    • The Korean Journal of Ceramics
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    • v.3 no.2
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    • pp.73-81
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    • 1997
  • In this paper, it is intended to present more reproducible and quantitative method for adhesion assemssement. In scratch test, micromechanical analysis on the stress state beneath the indenter was carried out considering the additional blister field. The interface adhesion was quantified as work of adhesion through Griffith energy approach on the basis of the analyzed stress state. The work of adhesion for DLC film/WC-Co substrate calculated through the proposed analysis shows the identical value regardless of distinctly different critical loads measured with the change of film thickness and scratching speed. On the other hand, uniaxial loading was imposed on DCL film/Al substrate, developing the transverse film cracks perpendicular to loading direction. Since this film cracking behavior depends on the relative magnitude of adhesion strength to film fracture strength, the quantification of adhesion strength was given a trial through the micromechanical analysis of adhesion-dependence of film cracking patterns. The interface shear strength can be quantified from the measurement of strain $\varepsilon$s and crack spacing $\lambda$ at the cessation of film cracking.

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A Study on the Measurement and Improvement of Service Quality using QFD in the Internet Shoppingmall (QFD를 이용한 인터넷 쇼핑몰의 서비스 품질 측정 및 개선에 관한 연구)

  • Jung Sang-Chul;Yoo Hae-Rim;Kim Myeong-Suk
    • Journal of Information Technology Applications and Management
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    • v.11 no.4
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    • pp.181-208
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    • 2004
  • By the developing of Internet. the environments of the company have rapidly been changed. Especially. managers in the Internet shoppingmall have been try to provide excellent e-Services to their customers. e-Service i~ defined comprised of all interactive services that are delivered on the Internet uSing advanced telecommunications. information, and multimedia technologies. but according to study of e-Satisfy. com[2000]. customer service through internet is still neither effective nor efficient and poor service will impact on company's profit but excellent service can improve their value and quality of the service or product. In order to customer-oriented e-Services. this study suggested the QFD linked with e-Service quality model for the Internet shoppingmall service system. which can help determine design characteristics being relevant to customer's e-Service quality requirements. this hybrid model have two stages. In the first stage. we do measure service quality and find priorities of service quality attribute by purchase process. and in the second stage. on the basis of priority of e-Service quality attributes, we find design characteristics to maximize customer satisfaction. From this study, we provide internet shoppingmall managers with the implications for improvement of service quality, measuring quality of e-service, providing design characteristics for customer-oriented service quality.

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An Empirical Study on the Korean Photonics Industrial Cluster Effects : Focusing on Absorptive Capacity and Corporate Performance (광주 광산업 클러스터 효과에 관한 연구 : 조직의 흡수역량과 기업성과에 미치는 영향에 관한 실증연구)

  • Bae, Jae-Kwon;Koo, Chul-Mo
    • Journal of Information Technology Applications and Management
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    • v.19 no.2
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    • pp.117-134
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    • 2012
  • Cluster industries are geographically concentrated and inter-connected by the flow of goods and services, which is stronger than the flow linking them to the rest of the economy. Photonics industries are one of the fastest growing high-tech industries in the world today. Especially, the city of Gwangju(South Korea) industrial cluster, a specialized complex in photonics industry, produced remarkable results in developing high-quality technologies since it launched the cluster program in 2005. Gwangju photonics industrial cluster will be ranked top level of the world photonics industry. In this sense, this study is aimed at proposing a new research model in which corporate performance influence factors of photonics industrial cluster (i.e., business environment, cooperative relationship, and industry-university-research institute partnership) affect absorptive capacity positively, leading to corporate performance eventually. This study developed a research model to explain the Korean photonics industrial cluster effects, and collected 91 survey responses from photonics based company managers in industrial cluster complex. To prove the validity of the proposed research model, PLS analysis is applied with valid 91 questionnaires. By employing PLS technique, the measurement reliability and validity of research variables are tested and the path analysis is conducted to do the hypothesis testing. In brief, the finding of this study suggests that corporate performance influence factors of photonics industrial cluster affect absorptive capacity positively, and corporate performance as well.